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*  Lassa Fever: Symptoms, Prevention And Treatment By WHO
Lassa fever is an acute viral haemorrhagic illness caused by Lassa virus, a member of the arenavirus family of viruses. It is ...
http://www.healthfitnessresource.com/th/lassa-fever-symptoms-prevention-and-treatment-by-who/
*  Table - Detection of Lassa Virus, Mali - Volume 16, Number 7-July 2010 - Emerging Infectious Disease journal - CDC
To determine whether Lassa virus was circulating in southern Mali, we tested samples from small mammals from 3 villages, including Soromba, where in 2009 a British citizen probably contracted a lethal Lassa virus infection. We report the isolation and genetic characterization of Lassa virus from an area previously unknown for Lassa fever.
https://wwwnc.cdc.gov/eid/article/16/7/10-0146-t1
*  Genetic analysis of heptad-repeat regions in the G2 fusion subunit of the Junin arenavirus envelope glycoprotein (Journal...
Title: Genetic analysis of heptad-repeat regions in the G2 fusion subunit of the Junin arenavirus envelope glycoprotein ... These findings support the inclusion of the arenavirus GP-C among the Class I viral fusion proteins and suggest pharmacologic ... Journal Article: Genetic analysis of heptad-repeat regions in the G2 fusion subunit of the Junin arenavirus envelope ... Taken together, our results indicate that {alpha}-helical coiled-coil structures are likely critical in promoting arenavirus ...
https://www.osti.gov/scitech/biblio/20779443
*  arenavirus
In rodents, arenavirus infection is typically asymptomatic. When arenaviruses infect humans, severe disease can result, such as ... The arenavirus glycoprotein, GP, is known to bind to TfR1. Ten GP amino acids were identified that are under positive selection ... Whether these novel arenaviruses actually cause snake IBD is not proven by this work. This question is underscored by the ... Three of these amino acids are located on the part of TfR1 that binds arenaviruses, and three are at the binding site for the ...
http://www.virology.ws/tag/arenavirus/
*  Virus di Chapare, un arenavirus recentemente scoperto
... il nuovo arenavirus di Chapare produce i sintomi emorragici clinici simili a quelli connessi con altri Nuovi arenavirus del ... "Dobbiamo imparare più circa questo virus: come è collegato con gli altri arenavirus, come causa la malattia, dove vive in ... un arenavirus precedentemente non riconosciuto, scoperto nei campioni del siero da un paziente in Bolivia rurale che finalmente ... di Sequenza dei segmenti specifici del virus più successivamente lo ha confermato come membro unico di Nuovi Arenavirus del ...
https://www.news-medical.net/news/2008/04/17/54/Italian.aspx
*  Breaking down arenavirus cell entry | Projects | H2020 | CORDIS | European Commission
Breaking down arenavirus cell entry. From 2015-10-01 to 2017-09-30 , BRACE Website ... Focusing on arenaviruses, these genome-wide surveys will reveal host factors indicative of virus entry tactics never observed ... examine in detail the virus-host interplay with these factors and will identify promising new antiviral targets for arenavirus ...
https://cordis.europa.eu/project/rcn/195945_en.html
*  Cleavage of the Glycoprotein of Arenaviruses | SpringerLink
The arenaviruses are a large family of emerging negative-stranded RNA viruses that include several severe human pathogens ... Old World arenaviruses New World arenaviruses Lassa virus Machupo virus Junin virus Glycoprotein Proprotein convertases ... Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategies ... A new arenavirus in a cluster of fatal transplant-associated diseases. N Engl J Med. 2008;358:991-8.CrossRefPubMedGoogle ...
https://link.springer.com/chapter/10.1007%2F978-3-319-75474-1_3
*  Viruses | Free Full-Text | Envelope Glycoprotein of Arenaviruses
Arenaviruses are comprised of two RNA genome segments and four proteins, the polymerase L, the envelope glycoprotein GP, the ... In a first part of our review, we cover basic aspects and newer developments in the biosynthesis of arenavirus GP and its ... A second part will then highlight the potential of SKI-1/S1P-mediated processing of arenavirus GPC as a novel target for ... A crucial step in the arenavirus life-cycle is the biosynthesis and maturation of the GP precursor (GPC) by cellular signal ...
http://mdpi.com/1999-4915/4/10/2162/xml
*  Viruses | Free Full-Text | Animal Models, Prophylaxis, and Therapeutics for Arenavirus Infections
The majority of these viruses are rodent-borne and the arenavirus family can be divided into two groups: the Lassa-Lymphocytic ... Arenavirus-induced disease may include characteristic symptoms ranging from fever, malaise, body aches, petechiae, dehydration ... Supportive care and ribavirin remain the predominant strategies for treating most of the arenavirus-induced diseases. Therefore ... This article reviews the current arenavirus animal models and prophylactic and therapeutic strategies under development to ...
http://mdpi.com/1999-4915/4/9/1802
*  Arenavirus | Article about arenavirus by The Free Dictionary
Find out information about arenavirus. A family of ribonucleic acid animal viruses consisting of a single genus, Arenavirus, ... having an enveloped, spherical pleomorphic form Explanation of arenavirus ... redirected from arenavirus). Also found in: Dictionary, Thesaurus, Medical, Wikipedia.. Related to arenavirus: bunyavirus ... Human infection with an arenavirus is likely to be very uncommon.. Arenavirus Infection Linked to Deaths in California ...
http://encyclopedia2.thefreedictionary.com/arenavirus
*  Receptor determinants of zoonotic transmission of New World hemorrhagic fever arenaviruses | PNAS
2002) Arenaviruses I: The epidemiology molecular and cell biology of arenaviruses. Curr Top Microbiol Immunol 262:V-XII.. ... 2002) Arenaviruses II: The molecular pathogenesis of arenavirus infections. Curr Top Microbiol Immunol 263:V-XII.. ... Rodents of the Muridae family are the natural hosts of most arenaviruses, and the geographic distribution of each arenavirus is ... Arenavirus) composed of at least 24 viruses (2, 3). Based on their antigenic properties, arenaviruses have been classified into ...
https://www.pnas.org/content/105/7/2664?ijkey=bf4cc233727c2057a5358f6879445a148a72c8f2&keytype2=tf_ipsecsha
*  Arenavirus - Wikipedia
At least eight arenaviruses are known to cause human disease. The diseases derived from arenaviruses range in severity. Aseptic ... The life cycle of the arenavirus is restricted to the cell cytoplasm. Within the family Arenaviridae, arenaviruses were ... Virus Pathogen Database and Analysis Resource (ViPR): Arenaviridae Arenaviruses "Arenavirus". NCBI Taxonomy Browser. 11618. ... Most of the Arenaviruses caught by humans are within their own homes when these rodents seek shelter. The virus can be caught ...
https://en.wikipedia.org/wiki/Arenavirus
*  Viruses | Free Full-Text | Pathogenic Mechanisms Involved in the Hematological Alterations of Arenavirus-induced Hemorrhagic...
In this article, we present the current knowledge about the hematological alterations present in VHF induced by arenaviruses, ... caused by arenaviruses are acute diseases characterized by fever, headache, general malaise, impaired cellular immunity, ... In the rodent, arenaviruses usually establish a persistent chronic infection with few symptoms [1]. However, arenaviruses may ... Rodas, J.D.; Salvato, M.S. Tales of mice and men: Natural history of arenaviruses. Rev. Col. Cienc. Pec. 2006, 19, 382-400. [ ...
http://www.mdpi.com/1999-4915/5/1/340/htm
*  Novel Arenavirus Infection in Humans, United States - Volume 17, Number 8-August 2011 - Emerging Infectious Diseases journal -...
The arenaviruses (family Arenaviridae, genus Arenavirus) known to occur in North America include Whitewater Arroyo virus (WWAV ... Delgado S, Erickson BR, Agudo R, Blair PJ, Vallejo E, Albariño CG, Chapare virus, a newly discovered arenavirus isolated from a ... Fulhorst CF, Milazzo ML, Armstrong LR, Childs JE, Rollin PE, Khabbaz R, Hantavirus and arenavirus antibodies in persons with ... Human infection with arenaviruses in the Americas. Curr Top Microbiol Immunol. 2002;262:65-74.PubMed ...
https://wwwnc.cdc.gov/eid/article/17/8/11-0285_article
*  Viruses | Free Full-Text | Serological Assays Based on Recombinant Viral Proteins for the Diagnosis of Arenavirus Hemorrhagic...
However, these arenaviruses are classified as BSL-4 pathogens, thus making it difficult to develop diagnostic techniques for ... We recently developed arenavirus neutralization assays using vesicular stomatitis virus (VSV)-based pseudotypes bearing ... arenavirus recombinant glycoproteins. The goal of this article is to review the recent advances in developing laboratory ... is of great importance to detect these pathogens rapidly and specifically in order to minimize the risk and scale of arenavirus ...
https://www.mdpi.com/1999-4915/4/10/2097
*  The American Journal of Tropical Medicine and Hygiene | Arenavirus antibody in rodents indigenous to coastal southern...
This study provides the first evidence that New World arenaviruses occur in Los Angeles and Orange counties and northwestern ... and the first evidence that Peromyscus and Reithrodontomys species are naturally infected with New World arenaviruses. ... purpose of this study was to extend our knowledge on the geographic and natural rodent host ranges of New World arenaviruses in ... f Arenavirus antibody in rodents indigenous to coastal southern California. * S G Bennett, M L Milazzo, J P Webb Jr, C F ...
http://www.ajtmh.org/content/journals/10.4269/ajtmh.2000.62.626
*  New arenavirus discovered as cause of hemorrhagic fever outbreak in South Africa ... ( May 28 2009Scientists at Columbia Un...)
... arenavirus,discovered,as,cause,of,hemorrhagic,fever,outbreak,in,South,Africa,and,Zambia,medicine,medical news today,latest ... The previously unknown arenavirus, which was identified using genetic extracts of blood and liver from the victims and through ... A detailed genetic analysis of this novel arenavirus, named Lujo virus, after the sites of the outbreak (Lusaka, Zambia, and ... New arenavirus discovered as cause of hemorrhagic fever outbreak in South Africa and Zambia ...
http://www.bio-medicine.org/medicine-news-1/New-arenavirus-discovered-as-cause-of-hemorrhagic-fever-outbreak-in-South-Africa-and-Zambia-47683-1/
*  Novel Arenavirus Isolates from Namaqua Rock Mice, Namibia, Southern Africa - Volume 21, Number 7-July 2015 - Emerging...
We report the identification, isolation, and genetic characterization of 2 novel arenaviruses from Namaqua rock mice in Namibia ... These findings extend knowledge of the distribution and diversity of arenaviruses in Africa. ... Arenaviruses are feared as agents that cause viral hemorrhagic fevers. ... Ishii A, Thomas Y, Moonga L, Nakamura I, Ohnuma A, Hang'ombe B, Novel arenavirus, Zambia. Emerg Infect Dis. 2011;17:1921-4. DOI ...
https://wwwnc.cdc.gov/eid/article/21/7/14-1341_article
*  Arenavirus life cycle. 1. Cellular entry is mediated by | Open-i
1. Cellular entry is mediated by different cellular receptors (αDG for OW and NW clade C arenaviruses; TfR1 for NW Clade B). ... Why some arenaviruses can cause virulent human infections while others cannot, even though they are isolated from the same ... Why some arenaviruses can cause virulent human infections while others cannot, even though they are isolated from the same ... Mentions: The life cycle of arenaviruses starts with virus attachment and entry into cells (Figure 3). The OW and NW clade C ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4493475_pathogens-04-00283-g003&req=4
*  Welcome to CDC stacks | Novel Arenavirus Isolates from Namaqua Rock Mice, Namibia, Southern Africa - 31823 | Emerging...
Arenavirus Dispatch Emerging Diseases Namibia Novel Arenavirus Isolates From Namaqua Rock Mice, Namibia, Southern Africa Rock ... Two arenaviruses were detected in pygmy mice (Mus spp.) by screening 764 small mammals in Ghana. The Natal multimammate mouse ( ... Arenaviruses are feared as agents that cause viral hemorrhagic fevers. We report the identification, isolation, and genetic ... An infectious arenavirus was isolated from 5 of 27 California mice but none of the 7 other rodents... ...
https://stacks.cdc.gov/view/cdc/31823
*  Identification of Amino Acid Residues Critical for the Anti-Interferon Activity of the Nucleoprotein of the Prototypic...
Human infection with Arenaviruses in the Americas, p. 65-74. In M. B. Oldstone (ed.), Arenaviruses I, vol. 262. Springer-Verlag ... Arenavirus NP amino acid sequences. Sequence homology among different arenavirus NPs was based on the following sequences: LCMV ... This anti-IFN activity is shared by all arenaviruses so far examined, with exception of the New World arenavirus Tacaribe virus ... Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA. Proc. Natl. Acad. Sci. USA 103:4663-4668. [PubMed] ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2772779/
*  The American Journal of Tropical Medicine and Hygiene | Prevalence of Antibodies to Arenaviruses in Rodents from the Southern...
Antibody to at least one arenavirus was found in 220 (3.1%) of 7,106 rodents tested. The antibody-positive animals included Mus ... The results suggest that arenaviruses are widely distributed in the southern United States and that one or more indigenous ... arenaviruses are associated with Neotoma spp. in North America. ... geographic distribution and rodent host range of arenaviruses ... Prevalence of Antibodies to Arenaviruses in Rodents from the Southern and Western United States: Evidence for an Arenavirus ...
http://www.ajtmh.org/content/journals/10.4269/ajtmh.1996.54.570
*  Development of a New Tacaribe Arenavirus Infection Model and Its Use to Explore Antiviral Activity of a Novel Aristeromycin...
In vitro anti-arenavirus activity of MY-24. The activity of the aristeromycin derivative, MY-24, was investigated in several ... Ribavirin, included as a positive control, was active in the range of 8-16 µM versus the same panel of arenaviruses. MY-24 had ... Tacaribe virus (TCRV) is a nonpathogenic member of clade B that is closely related to the VHF arenaviruses at the amino acid ... Differential inhibition of type I interferon induction by arenavirus nucleoproteins. J Virol. 2007;81:12696-12703. [PMC free ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2940843/
*  Arenavirus taxonomy: a review
Murphy, Frederick A. (‎1975)‎. Arenavirus taxonomy: a review. Bulletin of the World Health Organization, 52 (‎4-6)‎, 387 - 391 ...
https://apps.who.int/iris/handle/10665/261084