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*  "The Group IVA Cytosolic Phospholipase A2/C1P Interaction and Its Role " by Jennifer A. Mietla
... binds cPLA2α at a three amino acid sequence, which is located in the cationic β-groove of the C2 domain of cPLA2α. In this ... and the initial rate limiting step in the production of eicosanoids is the liberation of arachidonic acid (AA) from membrane ... and the initial rate limiting step in the production of eicosanoids is the liberation of arachidonic acid (AA) from membrane ... binds cPLA2α at a three amino acid sequence, which is located in the cationic β-groove of the C2 domain of cPLA2α. In this ...
https://scholarscompass.vcu.edu/etd/579/
*  Abstract 229: A Critical Role of Group IV Cytosolic Phospholipase A2α in the Development of Ang II-induced Hypertension and...
... most likely due to release of arachidonic acid and activation of NADPH oxidase and generation of ROS. Thus, cPLA2α could serve ...
http://hyper.ahajournals.org/content/60/Suppl_1/A229
*  Arachidonic acid- and acetylcholine-induced relaxations of rabbit aorta. | Hypertension
Arachidonic acid and acetylcholine had no effect on denuded rabbit aorta. Incubation of rabbit aorta with [14C]arachidonic acid ... and the effect of various agents on arachidonic acid- and acetylcholine-induced relaxations was examined. Arachidonic acid ... had little or no effect on arachidonic acid-induced relaxations. In contrast, nordihydroguaiaretic acid, metyrapone, NG- ... Arachidonic acid- and acetylcholine-induced relaxations of rabbit aorta.. S L Pfister, W B Campbell ...
http://hyper.ahajournals.org/content/20/5/682
*  COMPOSITIONS OF VERY LONG CHAIN POLYUNSATURATED FATTY ACIDS AND METHODS OF USE - Patent application
... linoleic acid, alpha-linolenic acid, eicosapentaenoic acid (EPA), arachidonic acid (ARA), docosahexaenoic acid (DHA), among ... tetracosanoic acid); 26:0, hexacosanoic acid; 28:0, octacosanoic acid/montanic acid; 30:0, triacontanoic acid/mellisic acid. [ ... fatty acids, exemplified by eicosapentaenoic acid (EPA), and the ω6 (n6) fatty acids, exemplified by arachidonic acid (ARA). ... Class name: Carboxylic acid, percarboxylic acid, or salt thereof (e.g., peracetic acid, etc.) higher fatty acid or salt thereof ...
http://www.patentsencyclopedia.com/app/20120071558
*  Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro
Measurement of arachidonic acid (AA) release. Isolated PMNs were incubated in RPMI medium containing 5% FBS and 0.5 μCi [3H]AA ... Role of mitogen-activated protein kinase-mediated cytosolic phospholipase A2 activation in arachidonic acid metabolism in human ... Activation of PMNs with IL-8/CXCL8 did not elicit arachidonic acid or LTB4 secretion in human PMNs. Thus, our findings suggest ... Phospholipase A2s (PLA2) are esterases that cleave glycerophospholipids at the sn-2 ester bond, releasing a fatty acid and a ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2848033/
*  Synthesis and Function of Cytochrome P450 4A1-Derived 20-Hydroxyeicosatetraenoic Acid in Rat Renal Arteries | Hypertension
20-hydroxyeicosatetraenoic acid (20-HETE) is the principal arachidonic acid metabolite in tubular and vascular structures of ... Synthesis and Function of Cytochrome P450 4A1-Derived 20-Hydroxyeicosatetraenoic Acid in Rat Renal Arteries. Michal Laniado- ... Synthesis and Function of Cytochrome P450 4A1-Derived 20-Hydroxyeicosatetraenoic Acid in Rat Renal Arteries ... Synthesis and Function of Cytochrome P450 4A1-Derived 20-Hydroxyeicosatetraenoic Acid in Rat Renal Arteries ...
http://hyper.ahajournals.org/content/36/Suppl_1/681.6
*  CREB-Mediated IL-6 Expression Is Required for 15(S)-Hydroxyeicosatetraenoic Acid-Induced Vascular Smooth Muscle Cell Migration ...
VSMC migration from media to intima plays a determinant role in atherosclerosis and restenosis.1-3 Arachidonic acid (AA) and ... Hydroxyeicosatetraenoic Acids Stimulate VSMC Migration. Toward understanding the role of eicosanoids in the pathophysiology of ... A novel role for activating transcription factor-2 in 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis. J Lipid Res. ... The lipoxygenase products of polyunsaturated fatty acids (PUFA) were shown to play a role in these diseases. cAMP response ...
http://atvb.ahajournals.org/content/29/6/809
*  15-Hydroxyeicosatetraenoic acid - Wikipedia
... a metabolite of arachidonic acid. Various cell types metabolize arachidonic acid to 15(S)-hydroperoxyeicosatetraenoic acid (15( ... 13E-eicosatetraenoic acid (15(R)-HpETE). Human cells release arachidonic acid (i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid) from ... Maas, R. L.; Turk, J; Oates, J. A.; Brash, A. R. (1982). "Formation of a novel dihydroxy acid from arachidonic acid by ... However this enzyme has a preference for metabolizing linoleic acid rather than arachidonic acid. It therefore forms linoleic ...
https://en.wikipedia.org/wiki/15-Hydroxyeicosatetraenoic_acid
*  Arachidonic acid - Wikipedia
Health effects of arachidonic acid supplementation[edit]. Arachidonic acid supplementation in daily doses of 1,000-1,500 mg for ... Arachidonic acid is not one of the essential fatty acids. However, it does become essential if a deficiency in linoleic acid ... Arachidonic acid is also used in the biosynthesis of anandamide.[17]. *Some arachidonic acid is converted into ... Dietary arachidonic acid and inflammation[edit]. Increased consumption of arachidonic acid will not cause inflammation during ...
https://en.wikipedia.org/wiki/Arachidonic_acid
*  Arachidonic Acid | Encyclopedia.com
A polyunsaturated fatty acid, CH3(CH2)3(CH2CH:CH)4(CH2)3COOH, that is essential for growth in mammals (see eicosanoid [1]). It ... arachidonic acid A long chain polyunsaturated fatty acid (20 : 4 ω6). Not strictly an essential fatty acid, since it can be ... arachidonic acid A polyunsaturated fatty acid, CH3(CH2)3(CH2CH:CH)4(CH2)3COOH, that is essential for growth in mammals (see ... arachidonic acid (ă-rak-i-don-ik) n. see essential fatty acid. ... "arachidonic acid." A Dictionary of Biology. . Encyclopedia.com. ...
https://www.encyclopedia.com/sports-and-everyday-life/food-and-drink/food-and-cooking/arachidonic-acid
*  Arachidonic Acid Derivatives
... releases arachidonic acid. ANSWER QUESTION: What enyzme acts on arachidonic acid and begins the process through which ... Derivatives of an n-6 Polyunsaturated Fatty Acid. An important family of regulatory molecules is derived from arachidonic acid ... QUESTION: What molecule is the source of arachidonic acid and where is it found? ANSWER QUESTION: Name the enzyme that, when ... Derivatives of n-3 Polyunsaturated Fatty Acids. The above introduces regulatory molecules derived from arachidonic acid. These ...
http://courses.washington.edu/conj/membrane/arachidonic.htm?cnn=yes
*  Arachidonic acid - Wikipedia
Arachidonic acid is also used in the biosynthesis of anandamide.[17]. *Some arachidonic acid is converted into ... Health effects of arachidonic acid supplementationEdit. Arachidonic acid supplementation in daily dosages of 1,000-1,500 mg for ... Dietary arachidonic acid and inflammationEdit. Increased consumption of arachidonic acid will not cause inflammation during ... and phosphatidic acid. BrainEdit. Arachidonic acid is one of the most abundant fatty acids in the brain, and is present in ...
https://en.m.wikipedia.org/wiki/Arachidonic_acid
*  Arachidonic Acid - Steroid .com
Naturally occurring, weight training can reduce levels creating a need for supplemental Arachidonic Acid. ... Arachidonic Acid is an Omega-6 fatty acid essential for muscle hypotrophy. ... Arachidonic Acid Chemical Composition. (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid. Formula: C20 H32 O2 ... Arachidonic acid (AA) is a naturally occurring omega-6 essential fatty acid. Its the principle building block for the synthesis ...
https://www.steroid.com/Arachidonic-Acid.php
*  Arachidonic Acid: When Inflammation Is Good
Get to know arachidonic acid and experience gains like the old days! ... Arachidonic acid isn't considered an essential fatty acid, because your body can synthesize it from linoleic acid in the liver ... Rett, B., & Whelan, J. (2011). Increasing Dietary Linoleic Acid Does Not Increase Tissue Arachidonic Acid Content in Adults ... WHAT IS ARACHIDONIC ACID?. Basically, ARA is the primary fatty acid responsible for inflammation in muscle tissue. This 20- ...
https://www.bodybuilding.com/fun/arachidonic-acid-when-inflammation-is-good.html
*  Understanding (AA) Arachidonic Acid - (Omega 6 - Pro Inflammatory Fat)
These are saturated fats, trans fats and (AA) arachidonic acid. I consider these to be really 'bad' fats. Arachidonic acids are ... arachidonic acid into the same rabbits they are dead within three minutes. The human body needs 'some' arachidonic acid, but ... Understanding (AA) Arachidonic Acid - (Omega 6 - Pro Inflammatory Fat). Dr. Barry Sears. Zone Living. CBN.com There are two ... is stimulated to make increased levels of arachidonic acid. (AA) is a long-chain omega-6 fatty acid. Enchaned production of ...
http://www.cbn.com/health/naturalhealth/drsears_ArachidonicAcid.aspx
*  arachidonic acid | Health Topics | NutritionFacts.org
Arachidonic acid is found in animal products, like poultry and eggs. The amount of arachidonic acid found in just one egg a day ... Arachidonic Acid and Mental Health. Arachidonic acid may trigger brain inflammation. High blood levels have been associated ... Inflammatory Remarks about Arachidonic Acid. Arachidonic acid may play a role in cancer, asthma, inflammatory bowel disease, ... Arachidonic acid is an inflammatory omega-6 fatty acid. Our bodies produce this nutrient, and its excess may lead to ...
https://nutritionfacts.org/topics/arachidonic-acid/
*  EPO - T 2370/09 (Arachidonic acid/MARTEK) of 26.5.2014
T 2370/09 (Arachidonic acid/MARTEK) of 26.5.2014. European Case Law Identifier:. ECLI:EP:BA:2014:T237009.20140526. ...
http://www.epo.org/law-practice/case-law-appeals/recent/t092370eu1.html
*  Role of ACOT7 in Arachidonic Acid Production and Inflammation | IntechOpen
Crystall Swarbrick, Noelia Roman and Jade K. Forwood (December 16th 2011). Role of ACOT7 in Arachidonic Acid Production and ... Crystall Swarbrick, Noelia Roman and Jade K. Forwood (December 16th 2011). Role of ACOT7 in Arachidonic Acid Production and ... Role of ACOT7 in Arachidonic Acid Production and Inflammation. By Crystall Swarbrick, Noelia Roman and Jade K. Forwood ... www.intechopen.com/embed/inflammatory-diseases-a-modern-perspective/role-of-acot7-in-arachidonic-acid-production-and- ...
https://www.intechopen.com/books/inflammatory-diseases-a-modern-perspective/role-of-acot7-in-arachidonic-acid-production-and-inflammation/
*  Combination Therapy of PPAR Ligands and Inhibitors of Arachidonic Acid in Lung Cancer
K. Yang, W. Ma, H. Liang, Q. Ouyang, C. Tang, and L. Lai, "Dynamic simulations on the arachidonic acid metabolic network," PLoS ... S. H. Hong, I. Avis, M. D. Vos, A. Martínez, A. M. Treston, and J. L. Mulshine, "Relationship of arachidonic acid metabolizing ... Y. Cao, A. T. Pearman, G. A. Zimmerman, T. M. McIntyre, and S. M. Prescott, "Intracellular unesterified arachidonic acid ... In devising therapeutic strategies, with the arachidonic acid products, greater attention to the impact of levels of mediators ...
https://www.hindawi.com/journals/ppar/2008/750238/
*  Nutrilon Premature (Alpha-Linolenic Acid; Arachidonic Acid; Calcium...) Nutricia
Alpha-Linolenic Acid*Arachidonic Acid*Calcium*Carbohydrates*Chloride*Choline*Copper*Docosahexaenoic Acid*Fat*Fiber*Folic Acid* ... Powder for Suspension; Oral; Alpha-Linolenic Acid 479 mg; Arachidonic Acid 115 mg; Calcium 727 mg; Carbohydrates 46.1 g; ... Folic Acid 170 mcg; Inositol 242 mg; Iodine 151 mcg; Iron 8.5 mg; L-Carnitine 11 mg; Linoleic Acid 3.376 g; Magnesium 48 mg; ... Linoleic Acid*Magnesium*Manganese*Moisture*Nucleotides*Phosphorus*Potassium*Protein*Selenium*Sodium*Taurine*Vitamin A*Vitamin ...
http://drugs-about.com/drugs-n/nutrilon-premature.html
*  Arachidonic Acid Muscle Building Sources - Mr Supplement Australia
Arachidonic Acid. What is Arachidonic Acid?. Arachidonic acid is one of the major omega 6 poly-unsaturated fatty acids. In the ... Where Does Arachidonic Acid Come From?. Arachidonic acid is not an essential fatty acid, meaning it is not necessary to have it ... Arachidonic Acid Side Effects, Safety and Negatives. Arachidonic acid is one of the chemicals in the body that control ... Stacking Arachidonic Acid. Stacking arachidonic acid with anti-inflammatories such as omega 3 oil should be avoided, since it ...
https://www.mrsupplement.com.au/arachidonic-acid
*  Arachidonic Acid in Cell Signaling book by Daniele Piomelli | 2 available editions | Alibris Books
Arachidonic Acid in Cell Signaling has 2 available editions to buy at Alibris ... Arachidonic Acid in Cell Signaling by Daniele Piomelli starting at $61.69. ... Arachidonic acid may serve as an intracellular second messenger in many cell types, as well as precursor for biologically ... Arachidonic acid may serve as an intracellular second messenger in many cell types, as well as precursor for biologically ...
https://www.alibris.com/Arachidonic-Acid-in-Cell-Signaling-Daniele-Piomelli/book/391252
*  Arachidonic acid metabolism by human monocytes. Studies with platelet-depleted cultures. | JEM
Arachidonic acid metabolism by human monocytes. Studies with platelet-depleted cultures.. N A Pawlowski, G Kaplan, A L Hamill, ... Arachidonic acid metabolism by human monocytes. Studies with platelet-depleted cultures.. N A Pawlowski, G Kaplan, A L Hamill, ... Purified human monocytes release and metabolize endogenous arachidonic acid (20:4) from phospholipid stores when challenged ...
http://jem.rupress.org/content/158/2/393
*  Aptamil 2 (Alpha-Linolenic Acid; Arachidonic Acid; Beta-Carotene...) Milupa
Arachidonic Acid*Beta-Carotene*Calcium*Carbohydrates*Chloride*Choline*Copper*Docosahexaenoic Acid*Fat*Folic Acid*Iodine*Iron*L- ... Powder for Suspension; Oral; Alpha-Linolenic Acid 0.92 g; Arachidonic Acid 121 mg; Beta-Carotene 762 mcg; Calcium 550 mg; ... Folic Acid 85 mcg; Iodine 44 mcg; Iron 7.7 mg; L-Carnitine 21 mg; Linoleic Acid 5.2 g; Magnesium 39 mg; Manganese 35 mcg; ... Vitamin B5 (Pantothenic Acid)*Vitamin B6*Vitamin C*Vitamin D3*Vitamin E (Alpha Tocopherol)*Vitamin H (Biotin)*Vitamin K*Zinc. ...
http://drugs-about.com/drugs-a/aptamil-2.html
*  Cytochrome P450-Derived Arachidonic Acid Metabolism in the Rat Kidney: Characterization of Selective Inhibitors | Journal of...
It is well recognized that the CYP-derived eicosanoids constitute a new member of the arachidonic acid cascade with important implications in the regulation of physiological and pathophysiological processes. These metabolites are formed endogenously in various tissues and exert potent biological effects on cellular functions. Studies of their role in normal and diseased cells and tissues are impeded by the difficulty in selectively targeting their synthesis or their effects, because these metabolites are generated from multiple closely related proteins of the CYP superfamily. Consequently, the development of enzyme inhibitors that target specific isoforms/reactions should aid in the study of their pathophysiological roles.. We have synthesized a series of fatty acid/arachidonic acid analogs and tested their potency and selectivity in inhibiting arachidonic acid epoxidation and ω-hydroxylation reactions in rat renal microsomes. Our study confirms that the ...
http://jpet.aspetjournals.org/content/284/3/966?ijkey=2efe7dbbff8d2e7a988deeead0c1db7cecc7b357&keytype2=tf_ipsecsha