Paperbase
Transcription activation by a variety of AraC/XylS family activators does not depend on the class II-specific activation ... the effector profile of this transcriptional regulator and the σ factor used by RNA polymerase to stimulate transcription from ... Mutational analysis of the highly conserved C-terminal residues of the XylS protein, a member of the AraC family of ... PhhR Binds to Target Sequences at Different Distances with Respect to RNA Polymerase in Order to Activate Transcription 10.1016 ...
Bacterial meningitis in the early postnatal mouse studied at single-cell resolution | eLife
With infection, a reduction is also seen for ERG, a pan EC transcription factor (Figure 5F and H). These data are consistent ... Arac et al., 2014). ... is both mediated by and up-regulates the transcription factor ... visualized with nuclear immunostaining for transcription factor PU.1 and cytoplasmic staining for CD206, show cytoplasmic ... 1983) Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid Science 219:983-985. ...
2016 Publications
2016) Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity. Proc Natl Acad Sci U ... 2016) Analysis of Amino Acid Substitutions in AraC Variants that Respond to Triacetic Acid Lactone. Protein Sci . 10.1002/pro. ... RIViT-seq technology could speed up associating transcription factors with their target genes. More ... 2016) Functional Metagenomics of Spacecraft Assembly Cleanrooms: Presence of Virulence Factors Associated with Human Pathogens. ...
Inactivation of the ptsI gene encoding enzyme I of the sugar phosphotransferase system of Streptococcus salivarius: effects on...
... but also indicate that additional factors may be important in regulating urease gene expression. ... When cells are cultivated at acidic pH values, the urease genes become derepressed and transcription is enhanced when cells are ... When cells are cultivated at acidic pH values, the urease genes become derepressed and transcription is enhanced when cells are ... a member of the AraC family of transcriptional activators. J Bacteriol 175:3459-3467 ...
US Patent for Cationic lipids for intracellular delivery of biologically active molecules Patent (Patent # 5,459,127 issued...
RNA-stabilizing factors and other transcription and translation regulating factors, antisense oligonucleotides, ribozymes, and ... araC), nucleosides such as acyclovir and gancyclovir having an acyclic ribose group, or the same nucleoside analogues as ... growth factors such as epidermal growth factor, growth hormone releasing factor, neural growth factor, and hormones such as ... tumor necrosis factor, tissue plasminogen activator, factor VIII, erythropoietin, ...
Detection of the bcl-2 t(14;18) Translocation and Proto-Oncogene Expression in Primary Intraocular Lymphoma | IOVS | ARVO...
Expression of immunoglobulin transcription factors in primary intraocular lymphoma and primary central nervous system lymphoma ... Systemic: thiotepa, vincristine Intrathecal: Ara-C). +. Systemic: MTX Intrathecal: MTX, Ara-C Radiation ×2: 30 and 49 Gy. 84+. ... Systemic: thiotepa, vincristine Intrathecal: Ara-C). +. Systemic: MTX Intrathecal: MTX, Ara-C Radiation ×2: 30 and 49 Gy. 84+. ... Systemic: dexamethasone; Intrathecal: Ara-C. +. Systemic: BCNU, cisplatin, temozolomide, Ara-C Intrathecal: MTX, BCNU ...
US Patent Application for ENGINEERED T CELLS AND TUMOR-INFILTRATING LYMPHOCYTES TO INCREASE TUMOR KILLING Patent Application ...
... transcription activation activity, transcription repression activity, transcription release factor activity, histone ... "Ara-C"); cyclophosphamide; taxoids, e.g., paclitaxel and docetaxel gemcitabine; 6-thioguanine; mercaptopurine; platinum ... hypoxia inducible factors (e.g., HIF-1 and HIF-2), Nuclear Factor-Kappa B (NF-B), Notch receptors (e.g., Notch1-4), c-Met, ... Epidermal Growth Factor receptor (EGFR) (in particular, EGFRvIII), platelet derived growth factor receptor (PDGFR), vascular ...
Acute Myeloid Leukemia (AML): Practice Essentials, Pathophysiology, Etiology
9] GATA2 is a transcription factor crucial for hematopoietic differentiation and lymphatic formation. Germline GATA2 mutations ... A phase 2 randomized study of low dose Ara-C with or without glasdegib (PF-04449913) in untreated patients with acute myeloid ... The prognosis depends on several factors. Increasing age is an adverse factor, because older patients more frequently have a ... A high BMI is a risk factor in younger patients with de novo acute myelogenous leukemia. Eur J Haematol. 2015 Aug 16. [QxMD ...
Rac1 AT1 required for Ang2-AT2 Activities for Cardiomyocytes and ECs where Tyr TAT and TAC Kinases required for Preventing...
Where, PG may stimulate IGFBP-5 gene transcription via a novel mechanism involving PR and CACCC-binding factors [41]. Previous ... Also, the increase in retinal GS elicited by Cytosine arabinoside (Ara-C) Ara-C is achieved through mechanisms which are quite ... heparin-binding epidermal growth factor-like growth factor (hbEGF), epidermal growth factor receptor (EGFR), erbB2, and insulin ... 1999) Progesterone Stimulation of Human Insulin-like Growth Factor-binding Protein-5 Gene Transcription in Human Osteoblasts Is ...
Frontiers | Hello from the Other Side: How Autoantibodies Circumvent the Blood-Brain Barrier in Autoimmune Encephalitis
Knowland D, Arac A, Sekiguchi KJ, Hsu M, Lutz SE, Perrino J, et al. Stepwise recruitment of transcellular and paracellular ... Blood-brain barrier function can be impaired by several factors including inflammatory cytokines, hormones (e.g., epinephrine ... TNF-α also induces formation of gaps between cell junctions by upregulating transcription of NF-κB and myosin light chain ... two factors that promote degradation of Claudin-5, Occludin, and ZO-1 (112, 113). ...
Characterisation of multiple heavy metal resistance loci in the genome of the novel species Cupriavidus neocaledonicus STM 6070...
CIENCIASMEDICASNEWS: NCI Drug Dictionary - National Cancer Institute | d/D/1
Nrf2, a leucine zipper transcription factor, plays a key role in redox homeostasis and cytoprotection against oxidative stress ... A chemotherapy regimen consisting of dexamethasone, high-dose cytarabine (ARA-C) and cisplatin (Platinol), used for the ... growth factors such platelet-derived growth factor (PDGF) on cell membranes, immobilizing growth factors on cell membranes and ... The intracellular protein IkappaBalpha functions as a primary inhibitor of the proinflammatory transcription factor NF-kappaB. ...
MRT67307 | Assay Way
Furthermore, we investigated the roles of nuclear factor (NF)-kB, IFN regulatory factor (IRF) 3 and IFN-b in the induction of ... Knowland, D., Arac, A., Sekiguchi, K., Hsu, M., Lutz, S.E., Perrino, J., Steinberg, G.K., Barres, B.A., Nimmerjahn, A., Agalliu ... RNA extraction and quantitative real-time reverse transcription (RT)-PCR. Total RNA was extracted from the cells after ... Furthermore, we investigated the roles of nuclear factor (NF)-kB, IFN regulatory factor (IRF) 3 and IFN-b in the induction of ...
Download A Short History Of Society: The Making Of The Modern World
Genome-Wide Characterization and Expression Analysis of income TGA Transcription Factors Identified a Novel TGA Gene Involved ... 33 model ARAC Research and Extension Day Handbook, Devonport, Tasmania, unionization users) rising the thumb strong revenue and ... factor America: The World War II Home Front. Johnston, Louis and Samuel H. Freedom from download a short history of society: ... low factor on the Arctic and the social anecdotal Unemployment on the Baltic. Western Europe x download a short history of ...
Characterization of AcrD, a Resistance-Nodulation-Cell Division-type multidrug efflux pump from the fire blight pathogen...
For immature pear infections, we first determined the expression of the sigma factor HrpL, which coordinates the transcription ... Expression of BaeR was achieved by using the vector pBAD24 where the expression is controlled by the PBAD promoter and araC. ... which controls a small set of adaptive factors involved in a unique envelope stress response in E. coli[23]. A BLASTP search ... indicating a growth phase-dependent transcription with the highest expression in the early exponential phase, acrD showed ...
immune-source.com
... p53 quickly devices transcription-independent apoptosis prior to the account activation of the transcription-dependent pathway ... Just category IA digestive support enzymes had been evidently suggested as a factor in human types of cancer. School IA PI3K ... JNJ-26854165 synergizes with AraC or perhaps doxorubicin to help cause p53-mediated apoptosis. To further determine the actual ... The year just gone to get a current review of your factor connected with ?7 nAChRs around mental digesting associated with ...
2020 Director's Challenge Awards | NIH Office of Intramural Research
The new technology achieves position-selective labeling of RNA (PLOR) by immobilizing the DNA template for transcription on a ... There is also increasing interest in factors associated with progression from pre-malignant states (including germline ... Animal Research Advisory Committee (ARAC). *Dual Use Research of Concern (DURC) Committee ... to incorporate non-canonical nucleotides in a site-specific manner during the course of conventional in vitro transcription. ...
2020 Director's Challenge Awards | NIH Office of Intramural Research
The new technology achieves position-selective labeling of RNA (PLOR) by immobilizing the DNA template for transcription on a ... There is also increasing interest in factors associated with progression from pre-malignant states (including germline ... Animal Research Advisory Committee (ARAC). *Dual Use Research of Concern (DURC) Committee ... to incorporate non-canonical nucleotides in a site-specific manner during the course of conventional in vitro transcription. ...
Bali H'ai | Robert Craft | The New York Review of Books
McPhees Balinese transcriptions undeniably influenced Brittens The Prince of the Pagodas, which makes more interesting use of ... especially when primed with glasses of arac, which he "tossed down with the sudden quickness of a lizard that has seen a fly." ... mentions what must have been a contributing factor, that McPhee "drank heavily and had an ugly temper when drunk" (he died of ... a performance by Béla Bartók and his wife at Amherst College in 1942 of some of the Balinese two-piano transcriptions6-and many ...
Emerging therapies for acute myeloid leukemia | Journal of Hematology & Oncology | Full Text
Acetylation of histones relaxes the condensed chromatin and exposes the promoter regions of genes to transcription factors. On ... Vosaroxin and vosaroxin plus low-dose Ara-C (LDAC) vs low-dose Ara-C alone in older patients with acute myeloid leukemia. Blood ... Efficacy of a type I FLT3 inhibitor, crenolanib, with idarubicin and high-dose ara-C in multiply relapsed/refractory FLT3+ AML ... Bromodomain and extraterminal (BET) proteins play a major role in the epigenetic regulation of gene transcription by binding to ...
bims-mibica 2022-11-20 papers
Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis. ... A genome-wide CRISPR knockout screen investigating resistance to doxorubicin and cytarabine (Dox/AraC) in human AML cell lines ... Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis. ... Mechanistically, acetyl-CoA synthesis was repressed by the transcription factors TEAD2 and E2A, previously unknown to control ...
Pre GI: BLASTP Hits
Transcription activator in PHB biosynthesis, AraC family. 4e-10. 65.9. NC_012560:2348202:2371675. 2371675. 2372721. 1047. ... their metabolic versatility as they can grow under a variety of growth conditions and do not need any organic growth factors. ... Transcription activator in PHB biosynthesis, AraC family. 4e-10. 65.9. NC_010511:4415731:4425985. 4425985. 4426191. 207. ... AraC family transcription regulator protein. 3e-10. 66.2. NC_011894:2503639:2511673. 2511673. 2511990. 318. Methylobacterium ...
Mantle Cell Lymphoma: Practice Essentials, Overview, Pathophysiology
In a study of sox11, a transcription factor involved in embryonic neurogenesis and tissue remodeling, Chen et al concluded that ... Modified VR-CAP/R+ara-C (bortezomib, rituximab, cyclophosphamide, doxorubicin, and prednisone, alternating with rituximab and ... No causative factor has been identified for mantle cell lymphoma (MCL) or for most patients with non-Hodgkin lymphoma (NHL) of ... In addition to age (ie, ,65 y), beta2-microglobulin was found to be a very strong prognostic factor, especially in patients ...
Cancer World 50 by European School of Oncology - Issuu
2011) High dose (HD-AraC) vs. standard dose cytosine arabinoside (SD-AraC) during induction and IL-2 vs. observation after ... One factor may be that we do not have good enough indicators to select the right treatment for patients during the last three ... description of the mechanism of retroviral transcription. But by that point in the book the reader has already been drawn into ... Therefore, the limiting factor genetics who received gemtuzumab in such patients will be the limits of had an improved overall ...
NVP-ADW742 - Crenolanib Inhibitor
Increased expression of insulin-like growth factor I is associated with Ara-C resistance in leukemia. Tohoku J Exp Med 2006; ... MAPK pathway, activation of ERK1 and ERK2 leads to various effects on transcription and metabolism, affecting cellular survival ... Insulin-like growth factors and neoplasia. Nat Rev Cancer 2004; 4(7): 505-518.. [46]Baserga R. The insulin-like growth factor-I ... Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human ...
Shop Merleau Ponty For Architects 2017
overpay our shop merleau factor of Death Photojournalist Mike Burke is led his growth into every % % and Agnathia on % - and be ... the ara-C-induced King Ghidorah. encoding the facts of Avengers: shop merleau ponty for, Spider-Man must Environ up to receive ... nt Here eXternal transcription( VLBI) village likely was an amyloid risk foot physiological to also 1 system( generations)( Ma ...