Browsing University of Nottingham Research Data Management Service by Author "Tanasescu, Radu"
Predictors of outcome of aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder in the United Kingdom Midlands ...
Magiran | فهرست مطالب «Nasim Nehzat»
Anti-myelin Oligodendrocyte Glycoprotein in Aquaporin-4 Negative Neuromyelitis Optica Spectrum Disorder ... International Journal of Preventive Medicine, Volume:12 Issue: 2, Feb 2021, P 4 ... Current Journal of Neurology, Volume:21 Issue: 4, Autumn 2022, PP 206 -210 ...
Plus it
2004) Potassium channel subunit Kv3.2 and the water channel aquaporin-4 are selectively localized to cerebellar pinceau. Brain ... 4G,H). These differences in slope were on the cusp of significance (ANOVA; p = 0.05). We then assessed differences in the F-I ... 4D). The spike rise time, however, did not undergo a significant change (Fig. 4E). In summary, the spike width and height ... Figure 4. Spike waveform properties and frequency as a function of injected current (F-I relation) in large, glutamatergic DCN ...
Astrocytes: the neglected stars in the central nervous system and drug addiction
Meanwhile, the endfeet which express water channel aquaporin 4 (AQP4) and Kir4.1 K+ channel play a special role in ion and ... Lv, Y, Jing, MY, Li, PY, Zhao, TY, Pang, C, Lu, GY, et al.. Aquaporin-4 deletion attenuates opioid-induced addictive behaviours ... Allen, NJ, Bennett, ML, Foo, LC, Wang, GX, Chakraborty, C, Smith, SJ, et al.. Astrocyte glypicans 4 and 6 promote formation of ... 4]), indicating that astrocyte may also play a part in drug memory as well, which may open a completely new area in ...
White Matter Water Diffusion Changes in Primary Sjögren Syndrome | American Journal of Neuroradiology
Loss of aquaporin 4 in lesions of neuromyelitis optica: distinction from multiple sclerosis. Brain 2007;130:1224-34. ... Recently, an autoantibody targeting the water channel protein aquaporin-4 (anti-aquaporin-4) has been discovered in ... Comparison of clinical, immunological and neuroimaging features between anti-aquaporin-4 antibody-positive and antibody- ... and there is evidence of an increased prevalence of anti-aquaporin-4 antibodies in patients with pSS.36⇓-38 Loss of myelin ...
Danicopan (ALXN2040) Add-On to ULTOMIRIS® (ravulizumab-cwvz) or SOLIRIS® (eculizumab) Met Primary Endpoint in ALPHA Phase III...
adults with a disease called neuromyelitis optica spectrum disorder (NMOSD) who are anti-aquaporin-4 (AQP4) antibody positive. ...
Fatal Familial Insomnia - Symptoms, Signs, Stages, Diagnosis, Treatment
Acute Disseminated Encephalomyelitis: Background, Pathophysiology, Epidemiology
Anti-aquaporin 4 antibody-positive acute disseminated encephalomyelitis. Brain Dev. 2014 May 16. [QxMD MEDLINE Link]. ... CNS aquaporin-4 autoimmunity in children. Neurology. 2008 Jul 8. 71(2):93-100. [QxMD MEDLINE Link]. ... Residual focal neurologic deficits remain in 4-30%. [54, 47, 58, 60, 61, 62, 55, 63, 85] Neurocognitive deficits after acute ... 4] Moreover, ADEM-associated concentrations of certain of these neutrophils (CXL7 neutrophil activator and the CL1, CCL17, and ...
Publications
Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein Autoantibody Status Predict Outcome of Recurrent Optic Neuritis. ... Brainstem and cerebellar involvement in MOG-IgG-associated disorder versus aquaporin-4-IgG and MS. J Neurol Neurosurg ... CNS Demyelinating Attacks Requiring Ventilatory Support With Myelin Oligodendrocyte Glycoprotein or Aquaporin-4 Antibodies. ... 2013 Jul; 6 (4):249-68 View PubMed. * Tillema JM, Hopkins S, Rodriguez M, Leach JL. Imaging of multiple sclerosis and related ...
Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets | Protocol (Translated to Portuguese)
Thesis/Theses examined by Egensperger, Rupert
Orphan Drug Market: Rare Diseases, Large Costs | Optum
"Epidemiology of aquaporin‐4 autoimmunity and neuromyelitis optica spectrum" Accessed at: https://www.ncbi.nlm.nih.gov/pmc/ ... In June 2019, the FDA approved use of Soliris® (eculizumab) to treat NMOSD.4 Originally developed to treat an unrelated blood ...
neuromyelitis NMO Archives - Guthy - Jackson CF
Background The presence of antibodies to aquaporin-4 (AQP4) has been identified as a key characteristic of neuromyelitis optica ... Original Article Neuromyelitis optica IgG does not alter aquaporin-4 water permeability, plasma membrane M1/M23 isoform content ... MONTREAL-Imaging studies of patients with neuromyelitis optica (NMO)-spectrum disorders reveal that effects of the aquaporin-4 ... Neuromyelitis optica IgG does not alter aquaporin-4 water permeability, plasma membrane M1/M23 isoform content, or ...
Science and Health Research Opportunities
Of particular interest is the water channel aquaporin-4 (AQP4) which mislocalises in epilepsy. AQP4 is generally expressed in ... 4-substituted gamma-lactone, a treatment for glaucoma and dry mouth). ...
Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain | Nature Neuroscience
b-d) Quantification (mean ± 95% CI) of aquaporin-4-positive (AQP4+) astrocytic endfoot coverage (t-test, equal variance: t = ... a) Confocal microscopy of immunolabeled aquaporin-4-positive astrocytic endfoot coverage of microvessels (lectin), GFAP- ... Figure 4: Diminished brain tissue oxygen levels and oxygen delivery in young pericyte-deficient Pdgfrb+/− mice.. ... c) Quantification (mean ± 95% CI) of CD13-positive pericyte coverage of cortical capillaries in 4 Pdgfrb+/+ and 4 Pdgfrb+/− ...
AquaGlo Plus Abrasion-Free Hydra Peeling Liquid
Uplizna (Inebilizumab-cdon Injection): Uses, Dosage, Side Effects, Interactions, Warning
... aquaporin-4 (AQP4) antibody positive.. DOSAGE AND ADMINISTRATION. Assessments Prior To First Dose Of UPLIZNA. Hepatitis B Virus ... Table 4 : Efficacy Results in Study 1 in anti-AQP4 Antibody Positive NMOSD Patients ... In Study 1 [see Clinical Studies], CD20+ Bcell counts were reduced below the lower limit of normal by 4 weeks in 100% of ... Advise patients to complete any required vaccinations at least 4 weeks prior to initiation of UPLIZNA. Administration of live- ...
MTHFR Research - Joyful Living Services
Aquaporin Chart Nobel peace prize winner Dr. Peter Agre MDs work on aquaporin has now began to be researched and correlated to ... In this chart you will find markers for tendencies based on aquaporin error. ... 4 ounces per bottle. For low Vitamin D, Thyroid. Most neurotransmitters are found in the small intestine and created there. TSH ... L- Glutamine Powder - 4750 mg, L-Alanyl-L-Glutamine - 250 mg, Aloe Vera P.E. 200:1 - 250mg, Marshmallow Root Powder Extract 4:1 ...
Optic neuritis - Symptoms, diagnosis and treatment | BMJ Best Practice US
Molecular mechanisms governing aquaporin relocalisation | Lund University Publications
Molecular mechanisms governing aquaporin relocalisation. *Mark. Markou, Andrea ; Unger, Lucas ; Abir-Awan, Mohammed ; Saadallah ... AQP, Aquaporin, Membrane trafficking, Osmosis. in Biochimica et Biophysica Acta - Biomembranes. volume. 1864. issue. 4. article ... The aquaporins (AQPs) form a family of integral membrane proteins that facilitate the movement of water across biological ... The aquaporins (AQPs) form a family of integral membrane proteins that facilitate the movement of water across biological ...
Ocular manifestations in systemic lupus erythematosus | British Journal of Ophthalmology
Aquaporin-4 antibodies (NMO-IgG) as a serological marker of neuromyelitis optica: a critical review of the literature. Brain ... Seroprevalence and specificity of NMO-IgG (anti-aquaporin 4 antibodies) in patients with neuropsychiatric systemic lupus ... testing for the aquaporin-4 autoantibody would help confirm the correct diagnosis of neuromyelitis optica.71 ,72 Ischaemic ... 4Harvard Medical School, Boston, Massachusetts, USA. *Correspondence to Dr C Stephen Foster, Massachusetts Eye Research and ...
Current Issue | Journal of Neurology, Neurosurgery & Psychiatry
Original research: Early rituximab treatment reduces long-term disability in aquaporin-4 antibody-positive neuromyelitis optica ... 4 May, 2023) Ryoichi Nakamura, Genki Tohnai, Masahiro Nakatochi, Naoki Atsuta, Hirohisa Watanabe, Daisuke Ito, Masahisa Katsuno ...
2017
Jainism, Science, and Intermittent Fasting
Intermittent Fasting Protects against Alzheimers Disease Possible through Restoring Aquaporin-4 Polarity. Front Mol Neurosci. ... Intermittent Fasting Protects against Alzheimers Disease Possible through Restoring Aquaporin-4 Polarity. Front Mol Neurosci. ... 4. Mattson MP, Longo VD, Harvie M. Impact of intermittent fasting on health and disease processes. Ageing Res Rev. 2016; 39:46- ... 4. Mattson MP, Longo VD, Harvie M. Impact of intermittent fasting on health and disease processes. Ageing Res Rev. 2016; 39:46- ...
JCI Insight -
Brain-wide glymphatic enhancement and clearance in humans assessed with MRI
Association of perivascular localization of aquaporin-4 with cognition and Alzheimer disease in aging brains. JAMA Neurol. 2017 ... Astrogliosis impaired aquaporin-4 dystrophin systems in idiopathic normal pressure hydrocephalus. [published online ahead of ... Test of the glymphatic hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain ... Geir Ringstad,1,2 Lars M. Valnes,3 Anders M. Dale,4,5,6 Are H. Pripp,7 Svein-Are S. Vatnehol,8 Kyrre E. Emblem,9 Kent-Andre ...
Mark H. Ellisman - Publications
Potassium channel subunit Kv3.2 and the water channel aquaporin-4 are selectively localized to cerebellar pinceau. Brain ... 4: 426-427. DOI: 10.1017/S143192760002225X 0.703. 1997. Perkins GA, Renken CW, Song JY, Frey TG, Young SJ, Lamont S, Martone ME ... 12: 51-4. PMID 25419960 DOI: 10.1038/Nmeth.3179 0.362. 2015. Bushong EA, Johnson DD, Kim KY, Terada M, Hatori M, Peltier ST, ... 4: 450-451. DOI: 10.1017/S1431927600022376 0.665. 1998. Lenzi D, Runyeon JW, Crum J, Ellisman MH, Roberts WM. Tomographic ...
Maryann E. Martone - Publications
Potassium channel subunit Kv3.2 and the water channel aquaporin-4 are selectively localized to cerebellar pinceau. Brain ... 4: 450-451. DOI: 10.1017/S1431927600022376 0.549. 1997. Perkins GA, Renken CW, Song JY, Frey TG, Young SJ, Lamont S, Martone ME ... 22: 4-7. DOI: 10.1109/Mcse.2020.2969730 0.332. 2020. Hsu C, Bandrowski AE, Gillespie TH, Udell J, Lin K, Ozyurt IB, Grethe JS, ... 4: 20. PMID 24093723 DOI: 10.1186/2041-1480-4-20 0.333. 2013. Larson SD, Martone ME. NeuroLex.org: an online framework for ...
KoreaMed
The Role of Aquaporin-4 in Cerebral Edema Formation after Focal Cerebral Ischemia in Rats Song YJ, Bae HR, Ha SU, Huh JT ... OBJECTIVE: To elucidate the role of aquaporin-4(AQP4) in cerebral edema formation, we studied the expression and subcellular ... 4. Implication of Neurological Pupil Index for Monitoring of Brain Edema Kim TJ, Ko SB ...
Soliris | European Medicines Agency