Apoptosis inducing factor is involved in initiating a caspase-independent pathway of apoptosis (positive intrinsic regulator of ... Apoptosis inducing factor is a flavoprotein. It also acts as an NADH oxidase. Another AIF function is to regulate the ... Apoptosis Inducing Factor (AIF) is a protein that triggers chromatin condensation and DNA fragmentation in a cell in order to ... Human genes encoding apoptosis inducing factor isozymes include: AIFM1 AIFM2 AIFM3 The apoptotic function of AIFs has been ...

... phosphorylated eukaryotic initiation factor 2,i,α,/i, (eIF2,i,α,/i,), phosphorylated protein endoplasmic-reticular- ... Furthermore, we found that GS-002 induced more cell apoptosis in ATF-3-overexpressing cells. These results suggest that the ... is rapidly upregulated under various stress conditions and plays an important role in inducing cancer cell apoptosis. NBM-TP- ... we found that GS-002 significantly inhibited cell proliferation and induced cell apoptosis in dose-dependent manners. Several ...

Interleukin 1β and Tumour Necrosis Factor α Induce Apoptosis in Renal Mesangial Cells In Vitro E Justice; E Justice ... E Justice, E Stylianou, J Savill; Interleukin 1β and Tumour Necrosis Factor α Induce Apoptosis in Renal Mesangial Cells In ... Interleukin-17D produced by alveolar epithelial type II cells alleviates LPS-induced acute lung injury via the Nrf2 pathway ... Myeloid cell-specific deletion of epidermal growth factor receptor aggravates acute cardiac injury ...

The antimicrobial peptide LL-37 triggers release of apoptosis-inducing factor and shows direct effects on mitochondria. *Mark ... for 2 h triggers release of the mitochondrial protein apoptosis-inducing factor (AIF) to the cytosol, whereas LL-37 causes no ... for 2 h triggers release of the mitochondrial protein apoptosis-inducing factor (AIF) to the cytosol, whereas LL-37 causes no ... for 2 h triggers release of the mitochondrial protein apoptosis-inducing factor (AIF) to the cytosol, whereas LL-37 causes no ...

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) efficiently induces apoptosis in glioma cell lines (3) but not ... Xiao C, Yang BF, Asadi N, Beguinot F, Hao C. Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing ... Human Astrocytoma Cells of WHO Grades I to IV for Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis ... Human Astrocytoma Cells of WHO Grades I to IV for Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis. ...

... induces apoptosis by binding to and inhibiting the antiapoptotic proteins Bcl-2 and Bcl-xL.57 Hypoxia induced apoptosis ... HIF-2α deficiency does not protect cells from hypoxia induced apoptosis as HIF-1α does.52 Whether HIF-3α induces apoptosis has ... hypoxia induced apoptosis is prevented. However, hypoxia by itself can also prevent apoptosis by inducing the expression of the ... 46 Increased IAP-2 expression is induced by the hypoxia induced transcription factor nuclear factor κB (NF-κB), and its ...

The Role of NF-κB as a Survival Factor in Environmental Chemical-Induced Pre-B Cell Apoptosis. Koren K. Mann, Stefan Doerre, ... The Role of NF-κB as a Survival Factor in Environmental Chemical-Induced Pre-B Cell Apoptosis. Koren K. Mann, Stefan Doerre, ... The Role of NF-κB as a Survival Factor in Environmental Chemical-Induced Pre-B Cell Apoptosis. Koren K. Mann, Stefan Doerre, ... Here, the role of NF-κB, a lymphocyte survival factor, in PAH-induced preB cell apoptosis was assessed. Analysis of DNA-binding ...

A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis. In: ... A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis. / ... A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis. ... T1 - A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis ...

Factor-Related Apoptosis-Inducing Ligand R2 and Increased Decoy Receptor Tumor Necrosis Factor-Related Apoptosis-Inducing ... Factor-Related Apoptosis-Inducing Ligand R2 and Increased Decoy Receptor Tumor Necrosis Factor-Related Apoptosis-Inducing ...

Tumor necrosis factor-related apoptosis-inducing ligand, NK: Natural killer, DC: dendritic cells, IFN: interferon, DISC: death ... inducing signaling complex, FADD : Fas associated death domain . ... Tumor necrosis factor-related apoptosis-inducing ligand, NK: ... is a type II transmembrane protein and is responsible for initiating apoptosis. Macrophages, natural killer (NK), dendritic ... "Tumor necrosis factor-related apoptosis- inducing ligand polymorphism.". Sohag Medical Journal, 27, 3, 2023, 53-56. doi: ...

Rat AIF(Apoptosis Inducing Factor) ELISA Kit. Rat AIF(Apoptosis Inducing Factor) ELISA Kit. To Order Contact us below: ... Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Apoptosis Inducing Factor ... Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Apoptosis Inducing Factor ... Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Apoptosis Inducing Factor ...

Introduction of these peptides into mammalian tumor cells caused the rapid onset of apoptosis, an outcome that correlates with ... A variety of studies implicate the E2F transcription factor as a critical regulator of the mammalian cell cycle. The E2F ... Apoptosis induced m mammalian cells by small peptides that functionally antagonize the rb-regulated e2f transcription factor ... Apoptosis induced m mammalian cells by small peptides that functionally antagonize the rb-regulated e2f transcription factor ...

This study investigated if tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) immunohistochemical expression in ... Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Expression Correlates to Temporomandibular Joint Disk Degeneration. ... This study investigated if tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) immunohistochemical expression in ... "Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Expression Correlates to Temporomandibular Joint Disk Degeneration" ( ...

Correction: Neutralization of tumor necrosis factor-related apoptosis-inducing ligand reduces spinal cord injury damage in mice ...

TNF-Related Apoptosis-Inducing Ligand, Tumor Necrosis Factor-alpha. Abstract. Tumor necrosis factor-related apoptosis-inducing ... Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor ... Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor ... TNF-Related Apoptosis-Inducing Ligand, Receptors, Tumor Necrosis Factor, Surface Plasmon Resonance, ...

... inhibits human adipocyte differentiation via caspase-mediated downregulation of adipogenic transcription factors. ...

... all of which in turn support oxidative phosphorylation and reduce apoptosis-inducing factor (AIF), mPTP, cytochrome c (Cyt-c), ... H. Zhou, P. Zhu, J. Guo et al., "Ripk3 induces mitochondrial apoptosis via inhibition of FUNDC1 mitophagy in cardiac IR injury ... "NAD+-dependent SIRT1 deactivation has a key role on ischemia-reperfusion-induced apoptosis," Vascular Pharmacology, vol. 70, pp ... Q.-L. Zhou, F. Teng, Y.-S. Zhang, Q. Sun, Y.-X. Cao, and G.-W. Meng, "FPR1 gene silencing suppresses cardiomyocyte apoptosis ...

... is an apoptosis-inducing membrane receptor for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). In this study, ... Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent ... 2006). Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP- ... Taken together, the present study demonstrates that curcumin enhances TRAIL-induced apoptosis by CHOP-independent upregulation ...

Focal cerebral ischemia activates the nuclear protein poly(ADP-ribose) polymerase (PARP). Apoptosis-inducing factor (AIF) is a ... N2 - Focal cerebral ischemia activates the nuclear protein poly(ADP-ribose) polymerase (PARP). Apoptosis-inducing factor (AIF) ... AB - Focal cerebral ischemia activates the nuclear protein poly(ADP-ribose) polymerase (PARP). Apoptosis-inducing factor (AIF) ... abstract = "Focal cerebral ischemia activates the nuclear protein poly(ADP-ribose) polymerase (PARP). Apoptosis-inducing factor ...

Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells. ... Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells. / ... Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells. In ... Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells. ...

Contributions of poly(ADP-ribose) polymerase-1 and -2 to nuclear translocation of apoptosis-inducing factor and injury from ... Contributions of poly(ADP-ribose) polymerase-1 and -2 to nuclear translocation of apoptosis-inducing factor and injury from ... Contributions of poly(ADP-ribose) polymerase-1 and -2 to nuclear translocation of apoptosis-inducing factor and injury from ... Contributions of poly(ADP-ribose) polymerase-1 and -2 to nuclear translocation of apoptosis-inducing factor and injury from ...

Dive into the research topics of Generation of a novel proform of tumor necrosis factor-related apoptosis-inducing ligand ( ... Generation of a novel proform of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein that can be ...

... and dependence on apoptosis-inducing factor (AIF). AA005 treatment also reduced expression of mitochondrial Complex I ... and induces gastric cancer cell death. However, the mechanisms underlying its cell-death-inducing activity are unclear. We used ... AA005 induces a unique type of cell death in colorectal adenocarcinoma cells, characterized by lack of caspase-3 activation or ... Our work provided new mechanisms for AA005-induced cancer cell death and novel clues for cancer treatment via AIF dependent ...

RT-induced damage to cancer cells leads to different outcomes, such as survival, senescence, or death. During RT, alterations ... tumor necrosis factor-related apoptosis-inducing ligand; TIGIT, T cell immune receptor with Ig and ITIM domains. NK cell, ... Anti-glucocorticoid-induced tumor necrosis factor-related protein (GITR) therapy overcomes radiation-induced treg ... T cells and the expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) on both neutrophils and Th1 cells ...

It was striking that the expression of tumour-necrosis-factor-alpha -related apoptosis-inducing ligand (TRAIL) among the ... Interleukin-10 up-regulates tumour-necrosis-factor-alpha-related apoptosis-inducing ligand (TRAIL) gene expression in mammary ... Interleukin-10 up-regulates tumour-necrosis-factor-alpha-related apoptosis-inducing ligand (TRAIL) gene expression in mammary ... apoptosis; death receptor; mammary gland. Publisher. PORTLAND PRESS. Indexed. SCI; SCIE; SCOPUS Document Type. Article. ...

... sensitizes breast cancer cells to TRAIL-induced apoptosis, including cell lines resistant to TRAIL-induced cytotoxicity. These ... The identified genes are involved in many critical cell processes, including apoptosis, growth factor-receptor signaling, cell- ... data identify novel molecular regulators of TRAIL-induced apoptosis in breast cancer cells and suggest strategies for the ... leading to apoptosis by activation of caspase-8 and the downstream executioner caspases, caspase-3 and caspase-7 (caspase-3/7 ...

Overall, phagocytosis is considered a beneficial phenomenon, since it eliminates dead cells and induces an anti-inflammatory ... Overall, phagocytosis is considered a beneficial phenomenon, since it eliminates dead cells and induces an anti-inflammatory ... ACAMPs, apoptotic cells-associated cellular patterns; AD, Alzheimers disease; AIF, apoptosis-inducing factor; APCs, antigen ... In the developing brain, hypoxia induces a whole range of death mechanisms, including apoptosis, pathological apoptosis, and ...

Mouse nerve growth factor suppresses neuronal apoptosis in valproic acid-induced autism spectrum disorder rats by regulating ... Mouse nerve growth factor suppresses neuronal apoptosis in valproic acid-induced autism sp ... These data suggest that mNGF suppressed neuronal apoptosis and ameliorated the abnormal behaviors in VPA-induced ASD rats, in ... Mouse nerve growth factor (mNGF), a neurotrophic factor, is critical for neuronal growth and survival, and the mNGF treatment ...

Hypoxia-induced vascular endothelial growth factor transcription and protection from apoptosis are dependent on alpha6beta1 ... Apoptosis. Breast Neoplasms. Cell Hypoxia. Cell Line, Tumor. DNA-Binding Proteins. Humans. Hypoxia-Inducible Factor 1. Hypoxia- ... EGF may induce a limited number of neuronal cells because it also enhanced apoptosis. Both NGF and a caspase inhibitor reduced ... Transcription Factors. Transcription, Genetic. Transcriptional Activation. Vascular Endothelial Growth Factor A. Cancer Biology ...

... and synergistically potentiated death receptor-induced apoptosis with tumor necrosis factor- related apoptosis-inducing ligand ... and synergistically potentiated death receptor-induced apoptosis with tumor necrosis factor- related apoptosis-inducing ligand ... and synergistically potentiated death receptor-induced apoptosis with tumor necrosis factor- related apoptosis-inducing ligand ... and synergistically potentiated death receptor-induced apoptosis with tumor necrosis factor- related apoptosis-inducing ligand ...