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*  Alkylating antineoplastic agent - Wikipedia
An alkylating antineoplastic agent is an alkylating agent used in cancer treatment that attaches an alkyl group (CnH2n+1) to ... List of hormonal alkylating antineoplastic agents "Alkylating Agents". US National Library of Medicine. Retrieved 2 August 2014 ... University of Nebraska page on alkylating agent drugs Alkylating antineoplastic agents at the US National Library of Medicine ... alkylating agents are classified under L01A. Many of the agents are known as "Classical alkylating agents". These include true ...
https://en.wikipedia.org/wiki/Alkylating_antineoplastic_agent
*  List of hormonal alkylating antineoplastic agents - Wikipedia
This is a list of dual hormonal and alkylating antineoplastic agents. Estramustine phosphate (Emcyt, Estracyt; Leo 299, NSC- ...
https://en.wikipedia.org/wiki/List_of_hormonal_alkylating_antineoplastic_agents
*  Alkylating Antineoplastic Agents Summary Report | CureHunter
A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to ... Alkylating; Antineoplastics, Alkylating; Antineoplastic Alkylating Drugs; Drugs, Antineoplastic Alkylating; Alkylating Agents, ... Alkylating Antineoplastic Drugs; Alkylating Antineoplastics; Alkylating Drugs, Antineoplastic; Antineoplastic Alkylating Agents ... Alkylating Antineoplastic Agents. Subscribe to New Research on Alkylating Antineoplastic Agents A class of drugs that differs ...
http://www.curehunter.com/public/keywordSummaryD018906-Alkylating-Antineoplastic-Agents.do
*  Misulban - Antineoplastic Agents, Immunosuppressive Agents, Alkylating Agents, ATC:L01AB01
Busulfan is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents ... Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the ...
http://pharmacycode.com/Misulban.html
*  Screening of natural products and alkylating agents for antineoplastic activity
On the other hand, alkylating agents such as cisplatin, cis- [PtCl2 (NH3) 2] have been widely used as antineoplastic agents for ... Screening of natural products and alkylating agents for antineoplastic activity. dc.contributor.advisor. Rees, Jasper. ... Screening of natural products and alkylating agents for antineoplastic activity. en_US. ... However, the use of cisplatin as an anticancer agent is limited due to toxicity and resistance problems. The aim of this ...
http://etd.uwc.ac.za/xmlui/handle/11394/3162?show=full
*  Chemotherapy - Wikipedia
Alkylating agents[edit]. Main article: Alkylating antineoplastic agent. Alkylating agents are the oldest group of ... Available agents[edit]. Main article: List of antineoplastic agents. There is an extensive list of antineoplastic agents. ... Siddik ZH (2005). Mechanisms of Action of Cancer Chemotherapeutic Agents: DNA-Interactive Alkylating Agents and Antitumour ... there are now many types of alkylating agents in use.[1] They are so named because of their ability to alkylate many molecules ...
https://en.wikipedia.org/wiki/Chemotherapeutics
*  Temodar and Sutent as Therapy for Melanoma - Full Text View - ClinicalTrials.gov
Antineoplastic Agents, Alkylating. Alkylating Agents. Molecular Mechanisms of Pharmacological Action. Antineoplastic Agents. ... The FDA approved DTIC in 1975 and high dose intravenous bolus rIL-2 in 1998 and these are the only agents approved for therapy ... The disease responds poorly to currently available chemotherapies and biological agents. The median survival in this patient ...
https://clinicaltrials.gov/ct2/show/NCT00304200
*  Dose Escalation Trial of WT1-specific Donor-derived T Cells Following T-Cell Depleted Allogeneic Hematopoietic Stem Cell...
Immunosuppressive Agents. Immunologic Factors. Physiological Effects of Drugs. Antineoplastic Agents, Alkylating. Alkylating ... Antineoplastic Agents. Antimetabolites, Antineoplastic. Antimetabolites. Molecular Mechanisms of Pharmacological Action. ...
https://www.clinicaltrials.gov/ct2/show/NCT01758328
*  Combination Chemotherapy in Treating Patients With AIDS-Related Hodgkin's Disease - Full Text View - ClinicalTrials.gov
Antineoplastic Agents, Alkylating. Alkylating Agents. Molecular Mechanisms of Pharmacological Action. Antineoplastic Agents. ... Antineoplastic Agents, Phytogenic. Topoisomerase II Inhibitors. Topoisomerase Inhibitors. Enzyme Inhibitors. Adjuvants, ... Immunosuppressive Agents. Immunologic Factors. Physiological Effects of Drugs. Antirheumatic Agents. ...
https://www.clinicaltrials.gov/ct2/show/NCT00003114
*  Evaluation of genotoxic effects of semicarbazide on cultured human lymphocytes and rat bone marrow.
Antineoplastic Agents, Alkylating / toxicity. Bone Marrow Cells / drug effects*. Cells, Cultured. Chromosomes / drug effects, ... 0/Antineoplastic Agents, Alkylating; 0/Mutagens; 0/Semicarbazides; 50-18-0/Cyclophosphamide ...
http://www.biomedsearch.com/nih/Evaluation-genotoxic-effects-semicarbazide-cultured/19819287.html
*  Hairy cell leukemia and variant in Taiwan: report of a variant case and literature review.
Antineoplastic Agents, Alkylating / therapeutic use. Bone Marrow / pathology. Chlorambucil / therapeutic use. Humans. ... 0/Antigens, CD; 0/Antineoplastic Agents, Alkylating; 0/Isoenzymes; 0/Tumor Markers, Biological; 305-03-3/Chlorambucil; EC 3.1.3 ...
http://www.biomedsearch.com/nih/Hairy-cell-leukemia-variant-in/21326814.html
*  A Study of Trabectedin in Patients With Advanced Ovarian Cancer
The purpose of this study is to test the safety and effectiveness of an investigational chemotherapy agent in patients with ... Antineoplastic Agents, Alkylating. *Alkylating Agents. *Adnexal Diseases. *Neoplasms. *Endocrine Gland Neoplasms. *Genital ...
http://www.knowcancer.com/cancer-trials/NCT00050414/
*  Malignant Giant Cell Tumor disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
Alkylating Agents. Not Applicable. 20. Antineoplastic Agents, Alkylating. Not Applicable. 21. Antirheumatic Agents. Not ...
https://www.malacards.org/card/malignant_giant_cell_tumor?search=actc1
*  Ifosfamide / ifosfamide NDA 090181 global drug patent coverage, generic alternatives and suppliers
Antineoplastic Agents, Alkylating Profile for product number 001. Active Rx/OTC/Discontinued:. RX. Dosage:. INJECTABLE; ...
https://www.drugpatentwatch.com/p/NDA/090181
*  Dacarbazine / dacarbazine NDA 075940 global drug patent coverage, generic alternatives and suppliers
Alkylating Activity Medical Subject Heading (MeSH) Categories for 075940. Antineoplastic Agents, Alkylating ...
https://www.drugpatentwatch.com/p/NDA/075940
*  Alkylating Agents - Pharmacology - Merck Veterinary Manual
Learn about the veterinary topic of Alkylating Agents. Find specific details on this topic and related topics from the Merck ... Antineoplastic Antibiotics. *Hormonal Agents. *Miscellaneous Antineoplastic Agents. *Ancillary Antineoplastic Agents. * ... Other Alkylating Agents:. Of the other subgroups of alkylating agents, several have limited but specific uses. ... Alkylating Agents By Lisa G. Barber, DVM, Assistant Professor, Cummings School of Veterinary Medicine, Tufts University ...
http://www.merckvetmanual.com/en-pr/pharmacology/antineoplastic-agents/alkylating-agents
*  Alkeran | definition of Alkeran by Medical dictionary
a trademark for an alkylating antineoplastic agent (melphalan). melphalan. An alkylating nitrogen mustard used to treat ovarian ...
https://medical-dictionary.thefreedictionary.com/Alkeran
*  Mycosis Fungoides (MF) - DrugBank
A widely used local anesthetic agent. [PubChem]. DB00262. Carmustine. A cell-cycle phase nonspecific alkylating antineoplastic ... It is also synergistic with some other antineoplastic agents and has immunosuppressive activity. [PubChem]. ... This agent also exhibits immunomodulatory and anti-inflammatory responses and inhibits ornithine decarboxylase, thereby ... The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone ...
https://www.drugbank.ca/indications/DBCOND0057197
*  Refractory Multiple Myeloma - DrugBank
A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other ... Carfilzomib is an injectable antineoplastic agent (IV only). Chemically, it is a modified tetrapeptidyl epoxide and an analog ... Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013. ... and it is the most potent DAC inhibiting agent available on the market. ...
https://www.drugbank.ca/indications/DBCOND0028542
*  Alkylation - Wikipedia
This mechanism of toxicity is relevant to the function of anti-cancer drugs in the form of alkylating antineoplastic agents. ... Nucleophilic alkylating agentsEdit. Nucleophilic alkylating agents deliver the equivalent of an alkyl anion (carbanion). The ... Electrophilic alkylating agentsEdit. Electrophilic alkylating agents deliver the equivalent of an alkyl cation. Alkyl halides ... Alcohols alkylate to give ethers: ROH + R'X → ROR'. When the alkylating agent is an alkyl halide, the conversion is called the ...
https://en.m.wikipedia.org/wiki/Alkylated
*  Pioglitazone and rofecoxib combined with angiostatically scheduled trofosfamide in the treatment of far-advanced melanoma and...
Antineoplastic Agents, Alkylating/adverse effects. MESH. Antineoplastic Combined Chemotherapy Protocols/therapeutic use. MESH. ...
https://epub.uni-regensburg.de/14439/
*  Estramustine - Semantic Scholar
This agent also exhibits anti-androgenic effects. (NCI04) ... Antineoplastic Agents, Alkylating. Drug Allergy. Estradiol. In ... To investigate the mechanism of action of the antineoplastic drug estramustine, we compared its effects on human prostate ...
https://www.semanticscholar.org/topic/Estramustine/167753
*  acute myeloblastic leukaemia without maturation 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Antineoplastic Agents, Alkylating / adverse effects. Humans. Leukemia, Myeloid. Male. Melphalan / adverse effects ... Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Tumor Suppressor Protein p53; EC 2.7.1.- / Phosphatidylinositol 3- ... Chemical-registry-number] 0 / Anthracyclines; 0 / Antineoplastic Agents, Phytogenic; 04079A1RDZ / Cytarabine; 6PLQ3CP4P3 / ... MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Chromosomes, Human, Pair 5. Cytarabine / analogs ...
http://www.bmlsearch.com/?kwr=acute+myeloblastic+leukaemia+without+maturation+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  T-cell Depleted Bone Marrow and G-CSF Stimulated Peripheral Stem Cell Transplantation From Related Donors in Treating Patients...
A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone ... Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S ... If you are a legal copyright holder or a designated agent for such and you believe a post on this website falls outside the ... Congener of CYTARABINE that is metabolized to cytarabine and thereby maintains a more constant antineoplastic action. ...
https://www.bioportfolio.com/resources/trial/126589/T-cell-Depleted-Bone-Marrow-and-G-CSF-Stimulated-Peripheral-Stem-Cell.html