This mechanism of toxicity is relevant to the function of anti-cancer drugs in the form of alkylating antineoplastic agents. ... Electrophilic alkylating agents Edit Triethyloxonium tetrafluoroborate is one of the most electrophilic alkylating agents.[6]. ... Nucleophilic alkylating agents Edit Nucleophilic alkylating agents deliver the equivalent of an alkyl anion (carbanion). The ... Electrophilic alkylating agents deliver the equivalent of an alkyl cation. Alkyl halides are typical alkylating agents. ...