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*  Oncotarget | Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in...
... a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects ... a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects ... Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast ... Hakomori S. Tumor-associated carbohydrate antigens defining tumor malignancy: basis for development of anti-cancer vaccines. ...
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=21959&path%5B%5D=69621
*  Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation - American College...
Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation. May 20, 2013 ... YOU ARE HERE: Home , Latest in Cardiology , Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter ... What is the predictive value of tumor marker carbohydrate antigen 125 (CA125) before and after transcatheter aortic valve ...
http://www.acc.org/latest-in-cardiology/journal-scans/2013/05/20/16/03/tumor-marker-carbohydrate-antigen-125-predicts-adverse-outcome
*  Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation | JACC:...
Tumor marker carbohydrate antigen 125 (CA125) is an emerging cardiac biomarker. In heart failure (HF), CA125 has shown to be ... Objectives This study sought to predict the value of tumor marker carbohydrate antigen 125 (CA125) before and after ... Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation ... Tumor Marker Carbohydrate Antigen 125 Predicts Adverse Outcome After Transcatheter Aortic Valve Implantation ...
http://interventions.onlinejacc.org/content/6/5/487
*  KAKEN - Research Projects | Development of immunotherapy for brain tumors targeting carbohydrate antigens of glycolipids ...
Development of immunotherapy for brain tumors targeting carbohydrate antigens of glycolipids. Research Project ... Publications] T.Yamaki: 'The requirement of host immune response to tumor cells to achieve tumor eradication by intratumoral ... Publications] Yamaki T.: 'The requirement of host immune response to tumor cells to achieve tumor eradication by intratumoral ... Publications] T.Yamaki: 'The requirement of host immune response to tumor cells to achieve tumor eradication by intratumoral ...
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-05807129/
*  reagents-immunoassay-tumor-marker-carbohydrate-antigen-mca
"Carbohydrate Antigen MCA Determination Reagents" , "Reagents, Immunoassay, Tumor Marker, Carbohydrate Antigen MCA" ... mucinlike carcinoma-associated antigen), a carbohydrate-related tumor marker. The detection of the tumor marker MCA is mostly ... IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen MCA. Definition : Immunoassay reagents intended to ... Home > Specialties > IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen MCA ...
http://www.medicalproductguide.com/term/5565/reagents-immunoassay-tumor-marker-carbohydrate-antigen-mca
*  reagents-immunoassay-tumor-marker-carbohydrate-antigen-ca-15-3
Carbohydrate Antigen 15-3) Determination Reagents" , "Reagents, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 15-3" ... a carbohydrate-related antigen tumor marker. The detection of the tumor marker CA 15 is mostly used in monitoring therapy and ... Home > Specialties > IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 15-3 ... IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 15-3. ...
http://productguide.optometricmanagement.com/term/4899/reagents-immunoassay-tumor-marker-carbohydrate-antigen-ca-15-3
*  ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-27.29
Carbohydrate Antigen 27.29) Determination Reagents" , "Reagents, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 27.29" ... IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 27.29. Definition : Immunoassay reagents intended to ... Home > Specialties > IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 27.29 ... a carbohydrate-related tumor marker. The detection of the tumor marker CA 27.29 is mostly used in monitoring therapy and ...
http://www.medicalproductguide.com/term/5559/ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-27.29
*  ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-19-9
Carbohydrate Antigen 19-9) Determination Reagents" , "Reagents, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 19-9" ... Home > Specialties > IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 19-9 ... IVD Test Reagent/Kits, Immunoassay, Tumor Marker, Carbohydrate Antigen CA 19-9. ... a blood-group carbohydrate-related tumor marker. The detection of the tumor marker CA 19-9 is mostly in diagnosis and ...
http://www.medicalproductguide.com/term/4900/ivd-test-reagent-kits-immunoassay-tumor-marker-carbohydrate-antigen-ca-19-9
*  Carbohydrates in Drug Design and Discovery (RSC Publishing)
... this book comprehensively covers the new and recent discoveries in the area of carbohydrate drug discovery.Carbohydrates in ... and the use of synthetic ligands based on carbohydrates as drugs has received much attention. Focussing on drug discovery from ... In recent years there has been increasing evidence of the importance of carbohydrates and glycoconjugates in biomedical ... Boosting Humoral Immune Responses to Tumor-associated Carbohydrate Antigens with Virus-like Particles. Zhaojun Yin and Xuefei ...
http://pubs.rsc.org/en/content/ebook/978-1-84973-939-9
*  Immunohistochemical Reactivity of the 14F7 Monoclonal Antibody Raised against N-Glycolyl GM3 Ganglioside in Some Benign and...
S. Zhang, C. Cordon Cardo, H. S. Zhang et al., "Selection of carbohydrate tumour antigens as targets for immune attack using ... Kawachi and Saida suggested that HD antigen is expressed on the carbohydrate chains of glycoproteins but not on those of ... These changes allow considering some gangliosides as tumor-associated antigens and they have been selected as possible target ... "Detection of gangliosides as N-glycolylneuraminic acid-specific tumor-associated Hanganutziu-Deicher antigen in human ...
https://www.hindawi.com/journals/isrn/2011/848909/
*  Rueda Lab: Bo Rueda, PhD - Massachusetts General Hospital, Boston, MA
Tumor-associated carbohydrate antigens (TACAs) are promising therapeutic targets. Increased presence of Sialyl-Thomsen-nouveau ... Treatment of ovarian cancer by targeting the tumor stem cell-associated carbohydrate antigen, Sialyl-Thomsen-nouveau. ... These explanted tumors and the primary tumors are genotyped and undergo cryopreservation using state of the art techniques. ... Molecular interrogation of gynecologic tumors.. My group molecularly interrogates gynecologic tumors to identify genes or ...
https://www.massgeneral.org/vcrb/research/researchlab.aspx?id=1754
*  Frontiers | Carbohydrate-Mimetic Peptides for Pan Anti-Tumor Responses | Immunology
... consequences of mimicking tumor associated carbohydrate antigens and the notion of reverse engineering to develop carbohydrate ... consequences of mimicking tumor associated carbohydrate antigens and the notion of reverse engineering to develop carbohydrate ... Here, we discuss our experience in bringing a tumor-associated carbohydrate mimetic peptide to the clinic. Emphasis is placed ... Here, we discuss our experience in bringing a tumor-associated carbohydrate mimetic peptide to the clinic. Emphasis is placed ...
https://www.frontiersin.org/articles/10.3389/fimmu.2014.00308/full
*  What Makes a Cancer Cell a Cancer Cell? - Holland-Frei Cancer Medicine - NCBI Bookshelf
Tumor-associated carbohydrate antigens can also be classified by the cell types expressing them as those (1) expressed on only ... Tumor-associated carbohydrate antigens can be classified into three groups38: (1) epitopes expressed on both glycolipids and ... Clinical trials of mucin-derived vaccines are underway.58 Some mucin antigens are shed from tumor cells and can be detected in ... by the fact that many of the monoclonal antibodies developed to tumor-cell-associated antigens recognize these carbohydrate ...
https://www.ncbi.nlm.nih.gov/books/NBK12516/
*  Faculty for Chemistry and Pharmacy LMU Munich - Prof. Dr. Anja Hoffmann-Röder
Synthesis of carbohydrates, peptides and glycokonjugates. *Tumor-associated carbohydrate antigens and cancer vaccines ... A. Hoffmann-Röder, J. Schoenhentz, S. Wagner, E. Schmitt, "Perfluoroalkylated amphiphilic MUC1 glycopeptide antigens as tools ... "Synthetic Antitumor Vaccines from Tetanus Toxoid Conjugates of MUC1 Glycopeptides with the Thomsen-Friedenreich Antigen and a ...
http://www.cup.uni-muenchen.de/de/departments/chemie/personen/prof-dr-anja-hoffmann-roeder/
*  KAKEN - Research Projects | Molecular mechanisms for maintenance of the integrity of nervous tissues by glycosphingolipids ...
Presentation] Regulatory mechanisms of malignant phenotypes of human cancers by tumor-associated carbohydrate antigens in the ... Presentation] Involvement of complex carbohydrates in the cancer phenotypes and therapeutic application.2012. *. Author(s). K. ... Presentation] Novel functions and mechanisms of complex carbohydrates elucidated by glycosyltransferase gene knockout2015. *. ... Journal Article] Trimeric Tn antigen on Syndecan-1 binds to integrins and enhances cancer metastasis via dynamic changes of ...
https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-23110008/
*  Plus it
Hakomori S. Possible functions of tumour-associated carbohydrate antigens. Curr. Opin. Immunol., 3: 646-653, 1991. ... Ragupathi G. Carbohydrate antigens as targets for active specific immunotherapy. Cancer Immunol. Immunother., 43: 152-157, 1996 ... Selection of tumor antigens as targets for immune attack using immunohistochemistry. I. Focus on gangliosides. Int. J. Cancer, ... We also examined antigen-binding specificity by ganglioside-binding ELISA (12) . The humanized KM8969 reacted strongly with N- ...
http://cancerres.aacrjournals.org/content/59/20/5323
*  Applications filed at Feb 01 2018 | METHODS OF TREATMENT USING AN INTERFERON GAMMA INHIBITOR | Patents.com
METHOD FOR TREATING A TUMOR WITH BIFUNCTIONAL AGENTS THAT BIND TO TUMOR CARBOHYDRATE ANTIGENS. A method for treating a tumor ... NOVEL MINOR HISTOCOMPATIBILITY ANTIGENS AND USES THEREOF. Novel minor histocompatibility antigens (MiHAs) are described. These ... COMPOSITION AND METHOD FOR AFFECTING THE BINDING OF ANTIGEN-BINDING POLYPEPTIDES TO ANTIGENS. The present invention provides a ... The antibody or antigen-binding portion thereof may... 2018/0030117. Synthetic Single Domain Antibody. The invention relates to ...
http://patents.com/ap-20180201-p109.html
*  Joint models for longitudinal and time-to-event data: a review of reporting quality with a view to meta-analysis | SpringerLink
Tumor marker carbohydrate antigen 125 predicts adverse outcome after transcatheter aortic valve implantation. JACC Cardiovasc ... Joint modeling tumor burden and time to event data in oncology trials. Pharm Stat. 2014;13(5):286-93.PubMedCrossRefGoogle ... Joint longitudinal and survival-cure models in tumour xenograft experiments. Stat Med. 2014;33(18):3229-40.PubMedCrossRefGoogle ... Synergism between circulating tumor necrosis factor receptor 2 and HbA(1c) in determining renal decline during 5-18 years of ...
https://link.springer.com/article/10.1186/s12874-016-0272-6
*  Plus it
Hakomori S. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. Cancer Res., 52: 257-331, 1989. ... Among the 10 tumors with low GnT-V expression, 6 tumors had low L-PHA staining, and 2 tumors had moderate L-PHA staining. ... Among the 10 tumors with high GnT-V expression, 6 tumors had high L-PHA staining, and 2 tumors had moderate L-PHA staining. ... The staining pattern of a tumor with high GnT-V expression and high L-PHA staining is shown in A and B. Staining for a tumor ...
http://clincancerres.aacrjournals.org/content/10/5/1773
*  Applications of Antibody-Lectin Sandwich Arrays (ALSA) to Pancreatic Cancer Diagnostics and Drug Discovery | SpringerLink
Fukuda M (1996) Possible roles of tumor-associated carbohydrate antigens. Cancer Res 56:2237-2244PubMedGoogle Scholar ... Friedenreich antigens during tumor progression in breast cancer patients. Tumour Biol 9:190-194PubMedCrossRefGoogle Scholar ... Yu LG (2007) The oncofetal Thomsen−Friedenreich carbohydrate antigen in cancer progression. Glycoconj J 24:411-420PubMed ... Martensson S, Bigler SA, Brown M et al (1995) Sialyl-Lewis(x) and related carbohydrate antigens in the prostate. Hum Pathol 26: ...
https://link.springer.com/chapter/10.1007/978-1-4419-1160-5_13
*  Identification of Endothelial Cell Surface Carbohydrate-Binding Receptors by Carbohydrate Ligand Mimicry Peptides | Springer...
Substantial evidence suggests that cell surface carbohydrate antigens, particularly those containing fucose residues, are ... Fukuda M (1996) Possible roles of tumor-associated carbohydrate antigens. Cancer Res 56:2237-2244PubMedGoogle Scholar ... Substantial evidence suggests that cell surface carbohydrate antigens, particularly those containing fucose residues, are ... Our study demonstrated the usefulness of carbohydrate-ligand mimicry peptide for the identification of novel carbohydrate- ...
https://rd.springer.com/chapter/10.1007/978-1-4614-3381-1_5
*  N-glycosylation of serum proteins for the assessment of patients with IgD multiple myeloma | BMC Cancer | Full Text
Hakomori S. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv Cancer Res. 1989;52:257-331.View ... Next, we evaluated the association between the levels of serum N-glycomic structures and different tumour stages. For this ... Kannagi R, Izawa M, Koike T, Miyazaki K, Kimura N. Carbohydrate-mediated cell adhesion in cancer metastasis and angiogenesis. ... Many glycan structures of proteins can influence various aspects of the biological behaviours of tumour cells during ...
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-017-3891-3
*  Dr. Salvatore Patanè, MD - Cardiologia Ospedale San Vincenzo Taormina (Me) Azienda Sanitaria Provinciale di Messina, Contrada...
Pericardial effusion with elevated serum carbohydrate antigen 125 levels and ovarian tumor mass.. Authors:. Salvatore Patanè ... Prostate-specific antigen kallikrein and acute myocardial infarction: where we are. Where are we going?. Authors:. Salvatore ... Prostate-specific antigen kallikrein complexes and acute myocardial infarction.. Authors:. Salvatore Patanè Filippo Marte Mauro ... Prostate-specific antigen kallikrein: from prostate cancer to cardiovascular system.. Authors:. Salvatore Patanè Filippo Marte ...
https://www.pubfacts.com/author/Salvatore+Patane
*  Recent Advances in Biotechnology:: volume 3 | Bentham Science
Vaccine and Antibody Therapy Against Thomsen- Friedenreich Tumor-Associated Carbohydrate Antigens Open Access Plus ... Topics covered in this volume include the development of vaccines and antibodies against tumor-associated carbohydrate antigens ... Consequently, carbohydrate containing biologics are now used in therapeutic regimens. This volume provides a summary of the ... Carbohydrates (monosaccharides, oligosaccharides and polysaccharides) exist naturally in free from and as components of other ...
http://www.eurekaselect.com/142678/volume/3