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*  Expression of a functional CD3-Ti antigen/MHC receptor in the absence of surface CD2. Analysis with clonal Jurkat cell mutants....
Expression of a functional CD3-Ti antigen/MHC receptor in the absence of surface CD2. Analysis with clonal Jurkat cell mutants. ... Expression of a functional CD3-Ti antigen/MHC receptor in the absence of surface CD2. Analysis with clonal Jurkat cell mutants. ... To investigate the requirement for CD2 expression in activation of T lymphocytes via the CD3-Ti antigen/MHC receptor complex, ... In contrast, triggering of their CD3-Ti components resulted in the normal set of T lymphocyte-associated activation events, ...
http://jem.rupress.org/content/168/6/2077
*  Gentaur Molecular :FabGennix \ CD3, Antigen blocking peptide \ P-CD3-130
CD3, Antigen blocking peptide \ P-CD3-130 for more molecular products just contact us ... CD3 antigen gamma polypeptide (CD3 antigen, gamma polypeptide, isoform CRA_b). [CD3 gamma] T-cell surface glycoprotein CD3 ... We have also other products like : CD3, Antigen blocking peptide Related products : CD3, Antigen blocking peptide ... CD3E T3E] T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e). [ ...
http://www.antibody-antibodies.com/product_det.php?id=3097426&supplier=search&name=CD3,%20Antigen%20blocking%20peptide%20
*  The effect of artificial antigen-presenting cells with preclustered anti-CD28/-CD3/-LFA-1 monoclonal antibodies on the...
Design and Methods Our artificial antigen-presenting cells were generated with activating (anti-CD3), co-stimulating (anti-CD28 ... The activity of our artificial antigen-presenting cells was compared with that of anti-CD3/-CD28 coated immunomagnetic ... The effect of artificial antigen-presenting cells with preclustered anti-CD28/-CD3/-LFA-1 monoclonal antibodies on the ... The effect of artificial antigen-presenting cells with preclustered anti-CD28/-CD3/-LFA-1 monoclonal antibodies on the ...
http://www.haematologica.org/content/93/10/1523
*  The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex | PNAS
The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex. E K Barber, J D ... The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex ... The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex ... The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex ...
https://www.pnas.org/content/86/9/3277?ijkey=cd56f19b14b5ffd7b06a0115cef0051f775932af&keytype2=tf_ipsecsha
*  Catumaxomab - Wikipedia
It binds to antigens CD3 and EpCAM. It is in clinical trials in the United States currently and is used in Europe. It was ... By binding to such a cell via one arm, to a T lymphocyte via the other arm and to an antigen-presenting cell like a macrophage ... of an anti-EpCAM antibody and one half of an anti-CD3 antibody, so that each molecule of catumaxomab can bind both EpCAM and ... CD3. In addition, the Fc-region can bind to an Fc receptor on accessory cells like other antibodies, which has led to calling ...
https://en.wikipedia.org/wiki/Catumaxomab
*  A novel model for antigen-dependent activation of normal human T cells. Transmembrane signaling by crosslinkage of the CD3/T...
Transmembrane signaling by crosslinkage of the CD3/T cell receptor-alpha/beta complex with the cluster determinant 2 antigen.. ... A novel model for antigen-dependent activation of normal human T cells. Transmembrane signaling by crosslinkage of the CD3/T ... and not independent crosslinking of TCR and of CD2 antigen or crosslinking of either protein with the CD4 or CD8 antigen ... suggest that the CD2 antigen might be targeted for the regulation of antigen-specific T cell immunity (e.g., organ ...
http://jem.rupress.org/content/171/6/1965
*  A novel model for antigen-dependent activation of normal human T cells. Transmembrane signaling by crosslinkage of the CD3/T...
A novel model for antigen-dependent activation of normal human T cells. Transmembrane signaling by crosslinkage of the CD3/T ... and not independent crosslinking of TCR and of CD2 antigen or crosslinking of either protein with the CD4 or CD8 antigen ... suggest that the CD2 antigen might be targeted for the regulation of antigen-specific T cell immunity (e.g., organ ... Antigen presentation. FASEB J. 1989 Nov;3(13):2496-2502. [PubMed]. *Meuer SC, Acuto O, Hussey RE, Hodgdon JC, Fitzgerald KA, ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2187964/?lang=en-ca
*  Macrophage subtypes in symptomatic carotid artery and femoral artery plaques.
0/Antigens, CD; 0/Antigens, CD3; 0/Antigens, Differentiation, Myelomonocytic; 0/Biological Markers; 0/CD68 antigen, human ... Antigens, CD / analysis. Antigens, CD3 / analysis. Antigens, Differentiation, Myelomonocytic / analysis. Atherosclerosis / ... Macrophages and T cell numbers were detected in plaque sections by immunohistochemistry and anti CD68 and CD3 antibodies. Dual ...
http://www.biomedsearch.com/nih/Macrophage-Subtypes-in-Symptomatic-Carotid/22975154.html
*  Cd3g - T-cell surface glycoprotein CD3 gamma chain precursor - Mus musculus (Mouse) - Cd3g gene & protein
When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell ... All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement ... Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. ... membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. ... T-cell surface glycoprotein CD3 gamma chain. RAT. 182. UniRef50 ...
https://www.uniprot.org/uniprot/P11942
*  Patent US7507873 - Transgenic avians containing recombinant ovomucoid promoters - Google Patents
wherein the therapeutic protein is selected from the group consisting of marine MAb directed against t-lymphocyte antigen CD3, ... wherein the therapeutic protein is selected from the group consisting of murine MAb, directed against t-lymphocyte antigen CD3 ... Antibody was captured from the egg white in microplate wells coated with the antibodies target antigen. Antigen-antibody ... the antigen specific hMab produced by mammalian cells (11A and 11B), the antigen specific hMab produced by a transgenic hen (11 ...
http://www.google.com/patents/US7507873?dq=5920316
*  CD3E protein, human - Semantic Scholar
T-cell surface glycoprotein CD3 epsilon chain (207 aa, ~23 kDa) is encoded by the human CD3E gene. This protein plays a role in ... CD3E Antigen, Epsilon Polypeptide (Tit3 Complex), T3E (More). T-cell surface glycoprotein CD3 epsilon chain (207 aa, ~23 kDa) ... A conformational epitope expressed upon association of CD3-epsilon with either CD3-delta or CD3-gamma is the main target for ... We have performed immunofluorescence analysis of COS cells transfected with human CD3 genes and detergent permeabilized to ...
https://www.semanticscholar.org/topic/CD3E-protein%2C-human/716054
*  Anti-T Cell Receptor antibody [JOVI.1] (ab5465) | Abcam
CD3d antigen antibody. *CD3d antigen delta polypeptide (TiT3 complex) antibody. *CD3d molecule delta (CD3 TCR complex) antibody ... Two distinct types of T-cell antigen receptors have been identified: the alpha/beta heterodimer found on functional helper and ...
https://www.abcam.com/t-cell-receptor-antibody-jovi1-ab5465.html
*  CD3 Antibody (OKT3) - Low Endotoxin and Azide Free (NBP2-24867): Novus Biologicals
Mouse Monoclonal Anti-CD3 Antibody (OKT3) - Low Endotoxin and Azide Free. Validated: Flow, Flow-CS, Func, In vitro, In vivo, ... CD3-g, CD3-e, CD3-s and the zeta chain) to generate activation signals. CD3 is specially engaged in antigen recognition and is ... Home » CD3 » CD3 Antibodies » CD3 Antibody (OKT3) - Low Endotoxin and Azide Free ... Blogs on CD3. Check out the latest blog posts on CD3.. Transferrin and the blood brain barrier. Transferrin, an iron binding ...
https://www.novusbio.com/products/cd3-antibody-okt3_nbp2-24867
*  CD3G - Wikipedia
1991). "The CD3-gamma and CD3-delta subunits of the T cell antigen receptor can be expressed within distinct functional TCR/CD3 ... T cell antigen receptor (TCR) is associated on the T cell surface with a complex of protein called CD3. CD3G (gamma chain) is ... 1989). "Dephosphorylation of the human T lymphocyte CD3 antigen". Eur. J. Biochem. 181 (1): 55-65. doi:10.1111/j.1432-1033.1989 ... 1991). "Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor ...
https://en.wikipedia.org/wiki/CD3G
*  A) TCR-LAT assembly formation requires palmitoylation | Open-i
Antigens, CD3/immunology/isolation & purification. *Cell Fractionation/methods. *Cholesterol/isolation & purification. *Humans ... 1999). α-CD3 immunoisolates from ANJ3 contained TCR ζ-chain, albeit at a reduced immunoisolation efficiency, but lacked LAT and ... 1999). α-CD3 immunoisolates from ANJ3 contained TCR ζ-chain, albeit at a reduced immunoisolation efficiency, but lacked LAT and ... In contrast, a LAT variant mutated in the S-palmitoylation sites Cys 26 and Cys 29 was not recruited into the α-CD3 isolates ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2192654_JCB0003036.f5a&req=4
*  Measurement of T Cell Activation After 16‐hr In Vitro Stimulation with Concanavalin A - Current Protocols
Fluorochrome‐conjugated monoclonal antibodies that recognize cell surface antigens CD3, CD4, CD8, and CD69 (Table 6.28.1. ): * ... CD3. PerCP. CD3 versus side scatter, gate on lymphocytes, count 30,000. CD4. APC. CD69 versus CD4, count CD69+ and CD69- CD4 ... CD8 FITC, CD69 PE, and CD3 PerCP antibodies (e.g., FastImmune CD8 FITC, CD69 PE and CD3 PerCP antibody mix, BD Bioscience, ... Induction of CD69 antigen on normal CD4+ and CD8+ lymphocyte subsets and its relationship with the phenotype of responding T‐ ...
http://www.currentprotocols.com/WileyCDA/CPUnit/refId-cy0628.html?quicktabs_cp=materials
*  Cd3d - PrimePCR Assay and Template | Life Science | Bio-Rad
CD3 antigen, delta polypeptide Assay Type: EvaGreen Application: Gene Expression Unique Assay ID: dMmuEG5073499 Info: EG; Same ... CD3 antigen, delta polypeptide Assay Type: Probe Application: Gene Expression Unique Assay ID: dMmuCPE5110222 Info: FAM; Same ... CD3 antigen, delta polypeptide Assay Type: Probe Application: Gene Expression Unique Assay ID: dMmuCPE5110223 Info: HEX; Same ... CD3 antigen, delta polypeptide Assay Type: Probe Assay Design: Intron-spanning Application: Gene Expression Unique Assay ID: ...
http://www.bio-rad.com/en-us/prime-pcr-assays/gene/cd3d-mouse
*  Immunosuppressive activity of cyclosporine metabolites in vitro - Publikationsserver der Universität Regensburg
Antigen-Antibody Reactions. MESH. Antigens, CD3. MESH. Antigens, Differentiation, T-Lymphocyte/immunology. MESH. ...
https://epub.uni-regensburg.de/14746/
*  Different activation states of human lymphocytes after antibody-mediated stimulation via CD3 and the alpha/beta T-cell receptor...
Antigens, Differentiation/analysis. MESH. Antigens, Differentiation, T-Lymphocyte/physiology. MESH. Cyclosporins/pharmacology. ... Different activation states of human lymphocytes after antibody-mediated stimulation via CD3 and the alpha/beta T-cell receptor ... These differences are most likely related to the different specificities of the antibodies, alpha/beta TcR versus CD3, ... features that are usually found after stimulation by the IgG2a CD3 antibody OKT3 in soluble form. The stimulatory effect of ...
https://epub.uni-regensburg.de/14729/
*  Frontiers | Influence of tumors on protective anti-tumor immunity and the effects of irradiation | Oncology
NK cells are characterized by the absence of the characteristic T cell antigens CD3 and CD4 (Stobo et al., 1973). Based on ... Although not all tumor antigens are "self" antigens (e.g., EBV antigens, mutated p53), the majority are. For effective immunity ... Tumors might therefore release antigens and/or other non-antigen-specific factors that activate Treg cells, thereby mediating ... Algarra, I., Collado, A., and Garrido, F. (1997). Altered MHC class I antigens in tumors. Int. J. Clin. Lab. Res. 27, 95-102. ...
https://www.frontiersin.org/articles/10.3389/fonc.2013.00014/full
*  Transient Inhibition of Interleukin 4 Signaling by T Cell Receptor Ligation | JEM
Both soluble anti-CD3/anti-CD28 and antigen treatment of T cells inhibit IL-4 signaling. BALB/c lymph node cells and spleen ... Soluble Anti-CD3 or Antigen Also Inhibits IL-4-mediated Signaling.. To determine whether more physiologic modes of TCR ... For the signaling experiments using soluble anti-CD3 or antigen, lymph node and spleen cells from BALB/c mice or lymph node ... we tested the effect of soluble anti-CD3 or of antigen in the presence of APCs. ...
http://jem.rupress.org/content/192/8/1125
*  Comparison of cytokine expression among CD25+, CD25−C | Open-i
B-E) 105 CD4+ CD25+, CD4+ CD25−CD45RBlow and CD4+ CD25−CD45RBhigh T cells were stimulated with plate-bound anti-CD3 (10 μg/ml) ... is further enhanced by costimulation via cytotoxic T lymphocyte-associated antigen (CTLA)-4. As in prior studies, we found that ... B-E) 105 CD4+ CD25+, CD4+ CD25−CD45RBlow and CD4+ CD25−CD45RBhigh T cells were stimulated with plate-bound anti-CD3 (10 μg/ml) ... A) Purified CD4+CD25+, CD4+CD25− CD45RBlow and CD4+CD25−CD45RBhigh T cells were stimulated with plate-bound anti-CD3 (10 μg/ml ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2195935_JEM010274.f10&req=4
*  CD40L mRNA levels in the isolated CD4+ T cells.Expressi | Open-i
Antigens, CD3/metabolism. *CD4-Positive T-Lymphocytes/immunology. *CD40 Ligand/genetics/metabolism ... were activated in vitro by anti-CD3, and cytokines were quantified in supernatants. In purified blood CD4+ T cells, RNA of ... were activated in vitro by anti-CD3, and cytokines were quantified in supernatants. In purified blood CD4+ T cells, RNA of ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4403992_pone.0123546.g002&req=4
*  Patents filed at Dec 26 2017 | Rubber article reinforcing steel wire and rubber article using same | Patents.com
Anti-CD3 antibodies and methods of use thereof. The present invention is related to antibodies directed to the antigen CD3 and ... Antigen-binding protein directed against epitope in the CH1 domain of human IgG antibodies. The present disclosure relates to a ... Heterodimeric antibodies to CD3 X CD20. The present invention is directed to novel heterodimeric antibodies. ... The invention provides novel methods of administering anti-CD3 antibodies, e.g., via oral or mucosal delivery. The invention ...
http://www.patents.com/isd-20171226-p79.html