CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. ... Antigen References 1. Hintzen R, et al. 1994. Immunol. Today 15:307.. 2. Agematsu K, et al. 1995. J. Immunol. 154:3627. ... CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and ... Antigen Details Structure TNF-R superfamily, type I transmembrane glycoprotein, 50-55 kD Distribution Medullary thymocytes, T ...

CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. ... Antigen References 1. Knapp W, et al. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. ... View All CD27 Reagents Request Custom Conjugation Description. Clone. Applications. Purified anti-human CD27. M-T271. FC,IHC-P, ... CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70, and ...

... pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen ... Prasad KV, Ao Z, Yoon Y, Wu MX, Rizk M, Jacquot S, Schlossman SF (Jul 1997). "CD27, a member of the tumor necrosis factor ... Held-Feindt J, Mentlein R (2002). "CD70/CD27 ligand, a member of the TNF family, is expressed in human brain tumors". Int. J. ... SIVA1 has been shown to interact with CD27. Siva protein is a zinc-containing intracellular ligand of the CD4 receptor that ...

Cd27. Name: CD27 antigen. Synonyms: Cd27, S152, Tp55, Tnfrsf7. Type: Gene. Species: Mus musculus (mouse) ...

CD27 is found on peripheral T cells, memory B cells, and NK cells. ... The LG.3A10 antibody reacts with CD27, a member of the TNF receptor superfamily. ... Human Leukocyte Antigen Analysis * Hybridoma and Cell Line Development * Immunology Research * Intestinal Research ... The LG.3A10 antibody reacts with CD27, a 45 - 55 kDa member of the tumor necrosis factor receptor superfamily. CD27 is found on ...

... cell therapy targeting the B cell specific differentiation antigen CD19 has shown clinical efficacy in a subset of relapsed/ ... CD27-CD28- T cells predicted CR at 12 months with high accuracy (P,0.001). In vitro, CD3+CD8+CD27-CD28- compared to CD3+CD8+ ... Univariate and multivariate regression analyses showed that low levels of differentiated CD3+CD27-CD28- T cells (23.3 ± 19.3% ... Univariate and multivariate regression analyses showed that low levels of differentiated CD3+CD27-CD28- T cells (23.3±19.3% ...

The CD27 antigen becomes hyperphosphorylated on serine residues upon activation of T cells. Signaling through the CD27 antigen ... The CD27 antigen becomes hyperphosphorylated on serine residues upon activation of T cells. Signaling through the CD27 antigen ... A soluble 28-32 kDa form of CD27 is produced by lymphocytes upon cellular activation. Binding of the CD27 antigen, expressed on ... A soluble 28-32 kDa form of CD27 is produced by lymphocytes upon cellular activation. Binding of the CD27 antigen, expressed on ...

OriGene Anti-CD27 Monoclonal (OTI6D6), TrueMAB™, Catalog # TA812372. Tested in Western Blot (WB) applications. This antibody ... CD27 antigen; CD27L receptor; LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T-cell activation antigen CD27; T14; ... degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70. CD27-binding protein (SIVA), a ... High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors. CD70 expression requires ...

iNKT cell subsets were identified as described (Engel et al., 2016): NKT1 (CD27+NK1.1+), NKT2 (CD27+, NK1.1-, CD1d-Tethi, CD4+ ... and consequently antigen specificity) is related to their anatomical location and/or shaped by the antigens that these cells ... 2015) Antigen specificity of type I NKT cells is governed by TCR β-Chain diversity The Journal of Immunology 195:4604-4614. ... A semi-invariant vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen- ...

2018; see ANTIGENS, CD70 2007-2017; CD27 LIGAND was indexed under ANTIGENS, CD; MEMBRANE PROTEINS; and TUMOR NECROSIS FACTORS ... Antigens, CD70 CD27L Protein CD70 Antigen CD70 Antigens TNF Superfamily, Member 7 Tumor Necrosis Factor Ligand Superfamily ... A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds to CD27 ANTIGEN. It is found ... A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds to CD27 ANTIGEN. It is found ...

CD27 is a tumor necrosis factor receptor family member expressed on T and B cells ... CD27 is a costimulatory receptor (Int Immunol 1995;7:551) *On T cells, CD27 activates NFκB and promotes cell survival, antigen ... Triggering of CD27 by CD70 leads to shedding of soluble CD27 from cells by a protease (J Immunol 1991;147:29) *Soluble CD27 can ... Soluble CD27 can be measured in serum and is an indicator of the CD70 - CD27 interaction in vivo *CD27 deficiency should be ...

... and highlight key findings from human vaccination studies which show heightened responses to bacterial and viral antigens ... CD27+CD28+CD45RA+CD57−CD62L+CCR7+KLRG1− naïve cells) (185, 186). In parallel, the numbers and proportions of antigen- ... antigen-experienced memory T cell clones, repopulating blood with antigen-inexperienced naïve T cells (11, 12). In this ... it has been proposed that antigen-inexperienced naïve T cells could be "used up" due to ongoing differentiation into antigen- ...

CD27+CD21−CD11c+ pre-plasmablast memory B cells, CD27−IgD−CD11c−CD21+ DN1 cells, CD27−IgD− CD11c+ DN2 cells and CD27−IgD−CD11c− ... Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity. Cell 183, ... Amanna, I. J. Duration of humoral immunity to common viral and vaccine antigens. N. Engl. J. Med. 357, 1903-1915 (2007). ... We first quantified RBD-specific CD19+ B cells in the control and cancer cohorts using antigen tetramers (Fig. 4a). We also ...

CD27−CD127−CCR7−). The magnitude of expansion and cytokine production was comparable to those induced by well-characterized the ... Our data suggest that Rv3615c is a major target of Th1-type responses and can be a highly immunodominant antigen specific for M ... Here, we studied human pulmonary T-cell responses induced by the M. tuberculosis-specific antigen Rv3615c, a protein with a ... Mycobacterium tuberculosis Rv3615c is a highly immunodominant antigen and specifically induces potent Th1-type immune responses ...

In addition, red, yellow (involving chemokine ligand 10 (CXCL10), CD27 molecule (CD27) and runt‑related transcription factor 3 ... RUNX3)], green (involving angiopoietin‑like 4 (ANGPTL4), stanniocalcin 2 (STC2), and sperm associated antigen 4 (SPAG4)], and ... In conclusion, the 44‑gene prognostic prediction system involving ANGPTL4, STC2, CXCL10, SPAG4, CD27, MMP9 and RUNX3 may be ... Additionally, the prognostic prediction system involving 44 signature genes, including ANGPTL4, STC2, CXCL10, SPAG4, CD27, ...

Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with ... CD27, CD134, CDB7, or CD3ζ) derived from the T-cell receptor with or without a second costimulatory factor (CD28 or 4-1BB) ( ... CAR T cells bind antigens independent of human leukocyte antigens (HLAs), an important feature because HLA downregulation is a ... Chimeric Antigen Receptor (CAR) T-Cell Therapy. Innovations in immunotherapy have led to the development of multiple immune- ...

CD27 antigen precu ( 260) 236 47.0 5.9e-05 NP_690593 (OMIM: 109535,606843) tumor necrosis fac ( 203) 234 46.5 6.2e-05 NP_671716 ... CD27 ( 358) 236 47.1 7.2e-05 NP_683866 (OMIM: 603366) tumor necrosis factor rec ( 426) 237 47.4 7.2e-05 NP_001241 (OMIM: 109535 ... CD27 ( 405) 236 47.2 7.7e-05 XP_016883624 (OMIM: 109535,606843) PREDICTED: tumo ( 323) 234 46.8 8.3e-05 NP_002537 (OMIM: 239000 ...

... their role as antigen presenting cells (APCs), that also present CNS antigens, proinflammatory cytokines (IFN-γ, TNFα, IL-6) ... activated CD27- non-germinal center cells, CD27+ memory B cells and naive B cells in tonsils and blood [47]. Human ... Opsonized antigens are able to cross-link the BCR to the co-receptor, reducing the point of B cell activation and accelerating ... Even though in the case of T-dependent antigens it requires at least two independent signals, from cytokines and also CD40 [42 ...

T cells expressing CD27, CD28, or CD127 in AML, and a higher percentage of CD8+CD27-CD28- T cells (P , 0.001) (Figure 1B) with ... TIGIT and PD-1 impair tumor antigen-specific CD8+ T cells in melanoma patients. J Clin Invest. 2015;125(5):2046-2058.. View ... CD27−CD45RA+), and a reduced percentage of naive (CCR7+CD45RA+) and naive-like cells (CD27+CD45RA+) in AML patients relative to ... Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells. Blood. 2003;101(7):2711- ...

At screening CSF concentrations, adjusted for age and sex, of NFL, myelin basic protein (MBP), soluble CD27, chitinase 3-like 1 ... and B-cell maturation antigen were higher than in a group of symptomatic controls. Twenty-six patients (96%) in the dimethyl ...

The aim of the study was to investigate whether eosinophils have increased human leukocyte antigen (HLA)-DR expression in ... During acute infection, circulating RV-sIgD(-) B cells are predominantly large, CD38(high), CD27(high), CD138(+/-), CCR6(-), ... Furthermore, type I IFN receptor -/- adult mice infected with rotavirus shed equivalent quantities of viral antigen and with ... The results support the hypothesis that gut trafficking memory CD4+ T cells comprise cellular memory for intestinal antigens ...

CD8+ T-cell proliferation and cytokine secretion were assessed in an antigen-specific assay using claudin-6 as a model antigen ... HexaBody®-CD27 (GEN1053/BNT313) is a novel CD27 human monoclonal antibody with a functionally inert IgG1 Fc domain harboring a ... This unique mechanism of action distinguishes HexaBody-CD27 from other CD27-targeting monoclonal antibodies. In preclinical ... Background Activation of the T-cell co-stimulatory receptor CD27 and blockade of the PD-1:PD-L1 axis can augment antitumor ...

... peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a ... Primate B-1 cells generate antigen-specific B cell responses to T cell-independent type 2 antigens. J Immunol. 2013;190:3100-8 ...

Antigens, CD2. CD2 Antigens. Antigens, CD24. CD24 Antigen. Antigens, CD27. Tumor Necrosis Factor Receptor Superfamily, Member 7 ... Antigens, CD98 Heavy Chain. Fusion Regulatory Protein 1, Heavy Chain. Antigens, CD98 Light Chains. Fusion Regulatory Protein 1 ... Antigen Peptide Transporter-1. ATP-Binding Cassette Sub-Family B Member 2. ... Antigen Peptide Transporter-2. ATP-Binding Cassette, Sub-Family B, Member 3. ...

Antigens, CD2. CD2 Antigens. Antigens, CD24. CD24 Antigen. Antigens, CD27. Tumor Necrosis Factor Receptor Superfamily, Member 7 ... Antigens, CD98 Heavy Chain. Fusion Regulatory Protein 1, Heavy Chain. Antigens, CD98 Light Chains. Fusion Regulatory Protein 1 ... Antigen Peptide Transporter-1. ATP-Binding Cassette Sub-Family B Member 2. ... Antigen Peptide Transporter-2. ATP-Binding Cassette, Sub-Family B, Member 3. ...

Antigens, CD2. CD2 Antigens. Antigens, CD24. CD24 Antigen. Antigens, CD27. Tumor Necrosis Factor Receptor Superfamily, Member 7 ... Antigens, CD98 Heavy Chain. Fusion Regulatory Protein 1, Heavy Chain. Antigens, CD98 Light Chains. Fusion Regulatory Protein 1 ... Antigen Peptide Transporter-1. ATP-Binding Cassette Sub-Family B Member 2. ... Antigen Peptide Transporter-2. ATP-Binding Cassette, Sub-Family B, Member 3. ...

Antigens, CD2. CD2 Antigens. Antigens, CD24. CD24 Antigen. Antigens, CD27. Tumor Necrosis Factor Receptor Superfamily, Member 7 ... Antigens, CD98 Heavy Chain. Fusion Regulatory Protein 1, Heavy Chain. Antigens, CD98 Light Chains. Fusion Regulatory Protein 1 ... Antigen Peptide Transporter-1. ATP-Binding Cassette Sub-Family B Member 2. ... Antigen Peptide Transporter-2. ATP-Binding Cassette, Sub-Family B, Member 3. ...

Antigens, CD27 refers to molecules that bind to the CD27 protein on the surface of immune cells. These antigens can be either ... Antigens, CD79. A component of the B-cell antigen receptor that is involved in B-cell antigen receptor heavy chain transport to ... Antigens, CD79 are antigens that specifically bind to the CD79 receptor on B cells. When these antigens bind to the receptor, ... or foreign antigens, which are found on the surface of pathogens such as viruses and bacteria. The binding of antigens to CD27 ...

antigens, cd27 (1) * cd28 antigens (1) * gene expression (1) * genes (1) * memory (1) ...