Dendritic Cells | OriGene
Langerhans Cells (LCs): These cells reside in the skin and mucosal tissues and can migrate to lymph nodes upon antigen capture. ... CD11B. CD1C. CD272. CD33. CD8A. IL3RA. ITGAX. LY75. Catalog-No.. TA807953S 30 ul ... cDC1: These cells are very effective at presenting antigens to CD8+ T cells, a type of cytotoxic T cell that can kill infected ... cDC2: These cells are specialized in presenting antigens to CD4+ T cells, a type of helper T cell that helps coordinate the ...
Medical Science Monitor | Microarray Analysis of Differential Gene Expression Between Traumatic Temporomandibular Joint Fibrous...
αMβ2 (CD11b/CD18) and αLβ2 (CD11a/CD18), the 2 most broadly studied members of the β2 integrin subfamily, have diverse cell ... Sedlik C, Orbach D, Veron P, A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and ... In addition, PPI analysis supported these results, since 5 of 6 hub genes, namely PTPRC (CD45), CD86, ITGAM (CD11b), SYK, and ... and antigen processing and presentation. Combined with the results of day 14, a prolonged immune and inflammatory reaction was ...
LOC100240734: A Drug Target / Disease Biomarker (G100240734)
LC0072 is also known as CD11b, which is a cell adhesion molecule that is expressed in various tissues of the body, including ... LC0072 is a cell-surface antigen that is expressed in various tissues of the body, including the brain, spleen, and Peyers ... The variable region is responsible for recognizing specific antigens, while the constant region provides structural stability ...
March | 2019 | C Kit Inhibitors
... studies using DCs presenting tumor antigens 5. DCs are the most powerful antigen presenting cells with the unique ability to ... ACT targets myeloid phagocytes bearing the αMβ2 integrin CD11b/CD18 (Mac-1 or CR3), such as neutrophils, macrophages, or ... The antigen-presenting capacity of synovial macrophages has been assumed, due to their expression of MHC class II and ... Others showed that when a macrophage cell line was stimulated with IFN-γ and pulsed with antigen, these cells could induce a ...
ThermoPA132946VEGF （BIOTIN）赛默飞-上海易汇生物科技有限公
Thermo MIH9701 ANTI-HEPATITIS B SURFACE ANTI GEN ￥6,975.00 GEN. Thermo MIH9704 ANTI-HEPATITIS B SURFACE ANTI GEN ￥6,975.00 GEN ... Thermo MA516604 ANTI-CD11B EA ￥6,975.00 EA. Thermo MA516607 ANTI-CD3/CD4 EA ￥6,975.00 EA ... Thermo MIH9705 ANTI-HEPATITIS B SURFACE ANTI GEN ￥6,975.00 GEN. Thermo MIH9706 ANTI-HEPATITIS B SURFACE ANTI GEN ￥6,975.00 GEN ... Thermo PA185871 PIERCE ANTI-SHIGELLA GROUP ANTIGEN RABBIT POLYCLONAL ￥6,975.00 ANTIGEN RABBIT POLYCLONAL ...
Complement System - Immunology; Allergic Disorders - MSD Manual Professional Edition
Antibody-dependent, occurring when C1 interacts with antigen-IgM or aggregated antigen-IgG complexes ... CR3 (CD11b/CD18), CR4 (CD11c/CD18), and C1q receptors play a role in phagocytosis. ... Ab = antibody; Ag =antigen; C1-INH = C1 inhibitor; MAC = membrane attack complex; MASP = MBL-associated serine protease; MBL = ...
NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss | Molecular...
a Cell number of isolated Cd11b+ microglia cells from IKK2-CAPLP−CreERT2 mice is significantly increased compared to Cd11b+ ... heat mediated antigen retrieval was performed with sodium citrate (10 mM, pH 6.0, 0.05% Tween 20) and the tissue sections were ... a Bead-Isolated Cd11b+ microglia were subjected to FACS analysis using Cd11b-PE labeled antibody and revealed a purity of 83%. ... CreERT2 Cd11b+ microglia at 3 and 20 wpi. c IKK2-CAPLP−CreERT2 Cd11b+ microglia are activated towards an M1 pro-inflammatory ...
Division of Immunobiology - Research output
- Research Profiles at Washington University School of Medicine
Binding of self-antigens to Ia molecules. Lorenz, R. G., Chen, J. S., Williams, S. G. & Allen, P. M., Dec 1 1989, In: Cold ... Batf3-dependent cd11b low/- peripheral dendritic cells are gm-csf-independent and are not required for th cell priming after ... Biochemical anatomy of antigen processing. Nelson, C. A., Harding, C. V. & Unanue, E. R., Dec 1 1992, In: Cold Spring Harbor ... Binding of the antigen L glutamic acid60 L alanine30 L tyrosine10 (GAT) by thymocytes from genetic responder and nonresponder ...
CD34+ Corneal Stromal Cells are Haemopoietic Stem Cells | IOVS | ARVO Journals
Abstract: : Purpose: To re-evaluate CD34 antigen expression in normal mouse cornea using dual and triple staining techniques ... In contrast, the remaining population of CD45+ CD34- cells in the corneal stroma expressed CD11b, MHC Class II+ but not CD11c, ... Flow cytometry analyses confirmed the morphometric data showing that 68% of CD45+ cells co-express CD34 and CD11b while 22% are ...
The fibrocyte in pulmonary hypertension: we seek him here, we seek him there | European Respiratory Society
19] used CD11b, CD34 and vimentin as markers. Less information is available on the flow-cytometric technique used but it is ... The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ. Proc Natl Acad Sci ... CD11b was found to be upregulated on fibrocytes from PAH patients, suggesting activation. Based on this intriguing finding, it ... The study by Gambaryan et al. [19] also investigated the membrane expression of CD11b (an integrin, also known as complement ...
Guido Franzoso: H-index & Awards - Academic Profile | Research.com
Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages (103 citations) ... He has researched Cancer in several fields, including NFKB1, Reprogramming, Antigen, Disease and Cytotoxic T cell. ...
Special delivery! An oncolytic virus encoding IL-7 and IL-12
MHC-II was also found to be upregulated on M1 macrophages in the contralateral tumor, and CD11b+ DCs from the spleen were found ... The injected tumors showed increased infiltration by CD8+ T cells (including tumor antigen-specific cells), CD4+ T cells, NKT ... Genetic loss or antibody blockade of VISTA in antigen-specific naïve CD4+ T cells under tolerance-inducing conditions resulted ... These results suggest VISTA maintains quiescence and homeostatic tolerance of self-antigen-specific naïve T cells.. Contributed ...
Content Title Here :: Labguru
The antigen is extracted from the cell in an appropriate lysis buffer, and antibodies are added to the lysate to allow ... Biotinylated anti-CD3ε, anti-T-cell receptor (TCR)αβ, anti-Thy-1.2, and anti-Mac-1 (CD11b) were detected by streptavidin-Cy5 ( ...
NIMH » Macrophage Infection by HIV: Implications for Pathogenesis and Cure: Day One
They can present antigen, but they can also cross-present antigen, and theyre also essential to the acquisition of adaptive ... We have seen -- weve looked at CD11b, CD11c, CD68. We are trying to figure out what these cells are, but we -- hopefully well ... Of course antigen presentation, but vascular function and all sorts of functions that really wouldnt be classified as immune ... The first question is from Henry van Brocklin to Yanique, and its, "I may have missed this, but what is the antigen that you ...
YRC Public Data Repository - Gene Ontology GO Protein Search Results
gi,554470,gb,AAA41517.1, leukocyte common antigen B None gi,62641814, gi,... Rattus norvegicus gi,62641814,ref,XP_219540.3, ... gi,8917587,gb,AAF81280.1, integrin beta 2 alpha subunit; CD11b [Rattus norvegicus], gi,29789036,ref,... None ... gi,554468,gb,AAA41515.1, leukocyte common antigen None gi,554469 Rattus norvegicus gi,554469,gb,AAA41516.1, leukocyte common ...
Gunnar C Hansson | Göteborgs universitet
CD103(+)CD11b(+) Dendritic Cells Induce T(h)17 T Cells in Muc2-Deficient Mice with Extensively Spread Colitis ... Recombinant glycoprotein E produced in mammalian cells in large-scale as an antigen for varicella-zoster-virus-serology. ... Recombinant glycoprotein E produced in mammalian cells in large-scale as an antigen for varicella-zoster-virus serology. ... The leukocyte antigen CD43 is expressed in different cell lines of nonhematopoietic origin. ...
Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus |...
CD11b, CD62L and C5aR. SLE patients (n = 92) showed lower ROS production compared with healthy controls (n = 38) after ... Elghetany MT: Surface antigen changes during normal neutrophilic development: a critical review. Blood Cells Mol Dis. 2002, 28 ... To characterize the activation status of PMN in peripheral blood the expression of C5aR, CD11b and CD62L was investigated. SLE- ... The remaining leukocytes were stained for surface expression of CD14 (to exclude monocytes), CD10, CD11b, CD16, CD62L, and C5aR ...
BATF regulates collagen-induced arthritis by regulating T helper cell differentiation | Arthritis Research & Therapy | Full Text
... and CD11b for macrophages. BATF was detected in subsets of CD4+ T cells (, 80%), CD11b+ macrophages (~ 40%), and vimentin- ... Antigens were retrieved by incubating joint sections at 60 °C overnight with sodium citrate buffer (10 mM sodium citrate, 0.05 ... The following primary antibodies were used: mouse anti-CD4, mouse anti-B220, rat anti-CD11b (Abcam), rabbit anti-BATF ( ... BATF-expressing cells in synovial tissues were identified by double immunofluorescence labeling of vimentin for FLS, CD11b for ...
Comparison of sample fixation and the use of LDS-751 or anti-CD45 for leukocyte identification in mouse whole blood for flow...
We found that samples labeled with LDS-751 demonstrated decreased fluorescence intensity for granulocyte CD11b expression and ... purpose of this study was to determine if labeling leukocytes with a monoclonal antibody specific to leukocyte common antigen ( ... We found that samples labeled with LDS-751 demonstrated decreased fluorescence intensity for granulocyte CD11b expression and ... keywords = "CD11b, Flow cytometry, LDS-751, Mouse, Neutrophil, Paraformaldehyde, Reactive oxidative species", ...
The gut represents a potential entry site for an array of - small molecule inhibitors of pyruvate kinase M2
446859-33-2 and than DN cDC (40). Moreover, the latter are able to express CD11b upon lifestyle and so are recruited in PP ... and are necessary for antigen presentation to immune effector cells. This review focuses on recent advances, which have allowed ... the latter screen Rabbit Polyclonal to CCRL1 even more much less and CD11b SIRP at their surface than dome cDC2. Moreover, many ...
Morphine-induced changes in the function of microglia and macrophages after acute spinal cord injury | BMC Neuroscience | Full...
Notably, while we refer to CD11b+CD45+ cells as microglia and macrophages, as is convention, it is acknowledged that CD11b+CD45 ... Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared. ... The contusion injury significantly increases the number of CD11b total positive cells (A), percentage of CD11b positive cells ( ... Different CD11b antibodies were used for the CD86 and CD206 panels and the gating strategy was lightly adjusted to accommodate ...
Complement activation in progressive renal disease
Antigen-antibody complexes enhance the production of complement component C3 by human mesangial cells. J Am Soc Nephrol. 1997;8 ... CD11b/18. Macrophages Natural killer cells Neutrophils. iC3b. Cellular-extracellular matrix linkage Promotes phagocytosis of ... Modulation of antigen processing and presentation by covalently linked complement C3b fragment. Immunology. 1995;84:164-170. [ ... C6 depletion reduces proteinuria in experimental nephropathy induced by a nonglomerular antigen. J Am Soc Nephrol. 1991;2:894- ...
Gwendalyn Randolph - Research output
- Research Profiles at Washington University School of Medicine
Antigen presentation by monocytes and monocyte-derived cells. Randolph, G. J., Jakubzick, C. & Qu, C., Feb 2008, In: Current ... CD11b+, Ly6G+ cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection. ... B Cell-Mediated Antigen Presentation through MHC Class II Is Dispensable for Atherosclerosis Progression. Williams, J. W., ... CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen. Desch, A. N., Randolph, ...
SAMP1/YitFc mice develop ileitis via loss of CCL21 and defects in dendritic cell migration
Their CD11b+CD103+ DCs were defective in migration from the ileal lamina propria to the MLN. DCs from SAMP mice also had a ... which helps establish tolerance to foreign yet harmless antigens. We demonstrate that CCL21 is almost completely absent from ... Their CD11b+CD103+ DCs were defective in migration from the ileal lamina propria to the MLN. DCs from SAMP mice also had a ... Their CD11b+CD103+ DCs were defective in migration from the ileal lamina propria to the MLN. DCs from SAMP mice also had a ...
TGF-β/Smad3 signalling regulates the transition of bone marrowderived macrophages into myofibroblasts during tissue fibrosis |...
19, 20, 22, 32, 33]. Fibrocytes are a poorly defined off-shoot of the monocyte lineage in which CD45+CD34+CD11b+ monocyte ... Immunostaining was performed on 3 μm paraffin sections using a microwave-based antigen retrieval technique [26, 27, 48]. ... In the second set of studies, CD11b+ cells were isolated from fresh bone marrow by FACS, labelled in vitro with SP-DiOC18 ( ... In the second adoptive transfer model, analysis of dye-labelled CD11b+ bone marrow macrophages before and after entry into the ...
Splenic Ly6Chi monocytes contribute to adverse late post-ischemic left ventricular remodeling in heme oxygenase-1 deficient...
Flow cytometric analysis of a classical (CD45+ CD11b+ Ly6G− NK1.1− Ly6C++ CD43+), b intermediate (CD45+ CD11b+ Ly6G− NK1.1− ... but does express high levels of stem-cell antigen 1 (Sca-1) and c-kit [51]. In the bone marrow, the number of SKL cells (Sca-1+ ... Flow cytometric analysis of c classical (CD45+ CD11b+ Ly6G− NK1.1− Ly6C++ CD43+), d intermediate (CD45+ CD11b+ Ly6G− NK1.1− ... CD11b+ Ly6G− NK1.1− Ly6C++ CD43++) and d non-classical monocytes (CD45+ CD11b+ Ly6G− NK1.1− Ly6C+ CD43++) in the peripheral ...
CD11b Antibody | 13-ORB11009-100UG
CD11b Antibody Manufactured by Gentaur. Gentaur is the biggest antibody manufacturer worldwide. ... Indicaid Antigen 25 tests box * ROCHE - SARS-CoV-2 Rapid Antigen- 25 Tests ... Decrease Quantity of CD11b Antibody , Gentaur Increase Quantity of CD11b Antibody , Gentaur ... CD11b Antibody , Gentaur. (No reviews yet) Write a Review Write a Review. ...
IL2RB | Cancer Genetics Web
The expression of several antigens was co-regulated, suggesting common regulatory pathways. These antigens include CD11c/CD5, ... Accordingly, besides being CD56(-/+dim), they were CD11b(-/+dim) (heterogeneous), CD7(-/+dim) (heterogeneous), CD2(+) ( ... even when antigens belonged to entirely different gene families. Such antigen pairs were: CD11c/CD21; CD19/CD45; CD19/CD79b; ... Upregulation of surface antigen expression, induced by OMCs, should be applicable in antibody therapy in vitro and in vivo, and ...
N CCR2-- knockout mice, suggesting that MF59 triggers cell recruitmentN CCR2-- knockout mice, suggesting that | ITK inhibitor...
In addition, MF59 considerably increased the amount of antigen-loaded APCs in draining LNs in comparison to alum or non- ... MF59 promoted a additional speedy influx of CD11b cells within the muscle compared to other adjuvants (like alum and CpG ... Ultimately, immune responses enhanced by MF59 to tetanus and influenza antigens had been located to be independent of the ... elicited effects distant in the injection site and modulated gene transcription in LNs in an antigen-independent matter top to ...