Islet autoimmunity in human type 1 diabetes: initiation and progression from the perspective of the beta cell | DiabetologiaIslet autoimmunity in human type 1 diabetes: initiation and progression from the perspective of the beta cell | Diabetologia
... consistent with both antigen and epitope spreading [41]. Thus, dynamic antigen presentation by beta cells may be a driving ... autoreactive T cells differentiate into killers by engaging beta cell antigens on local antigen-presenting cells; initiating ... As antigen presentation by beta cells is greatly altered by various forms of stress (reviewed in [51] and further detailed ... The view that antigen presentation by beta cells is critical for progression of islet autoimmunity has been supported by ...
https://link.springer.com/article/10.1007/s00125-023-05970-z
The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies | Journal of Clinical ImmunologyThe 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies | Journal of Clinical Immunology
AD: autosomal dominant transmission; ADA: adenosine deaminase; Ag: antigen; AR: autosomal recessive transmission; β2m: bêta-2 ... Ab: antibody; AD: autosomal dominant transmission; Ag: antigen; ALPS: autoimmune lymphoproliferative syndrome; APS: autoimmune ...
https://link.springer.com/article/10.1007/s10875-017-0465-8
Acne and Genetics | SpringerLinkAcne and Genetics | SpringerLink
Tissue Antigens. 2010;76:411-5.. CAS PubMed Google Scholar *. Szabo K, Tax G, Teodorescu-Brinzeu D, et al. TNFα gene ...
https://link.springer.com/chapter/10.1007/978-3-540-69375-8_14?error=cookies_not_supported&code=d2fdb79b-2562-4385-b6f5-d52db64d1948
Exploratory Analysis of Plasma Neurotensin as a Novel Biomarker for Early Detection of Colorectal Polyp and Cancer | Discover...Exploratory Analysis of Plasma Neurotensin as a Novel Biomarker for Early Detection of Colorectal Polyp and Cancer | Discover...
Wanebo HJ, Rao B, Pinsky CM, Hoffman RG, Stearns M, Schwartz MK, Oettgen HF (1978) Preoperative carcinoembryonic antigen level ... Blood markers such as CEA and cancer antigen (CA) 19-9 have sub-optimal sensitivity and specificity, are exclusively used as ... Fletcher RH (1986) Carcinoembryonic antigen. Ann Intern Med 104(1):66-73 ...
https://link.springer.com/article/10.1007/s12672-019-00364-3
Pharmacokinetic modelling of N-(4-[18F]fluorobenzoyl)interleukin-2 binding to activated lymphocytes in an xenograft model of...Pharmacokinetic modelling of N-(4-[18F]fluorobenzoyl)interleukin-2 binding to activated lymphocytes in an xenograft model of...
Tissue Antigens 1974;4(4):269-74.. PubMed Google Scholar *. Innis RB, Cunningham VJ, Delforge J, Fujita M, Gjedde A, Gunn RN, ...
https://link.springer.com/article/10.1007/s00259-012-2176-y
Targeting Macrophages for Tumor Therapy | SpringerLinkTargeting Macrophages for Tumor Therapy | SpringerLink
Moreover, the genetic engineering of macrophages with chimeric antigen receptor (CAR) allows them to recognize tumor antigens ... Zhang C, Zhuang Q, Liu J, Liu X. Synthetic biology in chimeric antigen receptor T (CAR T) cell engineering. ACS Synth Biol. ... Designing chimeric antigen receptors to effectively and safely target tumors. Curr Opin Immunol. 2015;33:9-15. https://doi.org/ ... Human chimeric antigen receptor macrophages for cancer immunotherapy. Nat Biotechnol. 2020;38(8):947-53. https://doi.org/ ...
https://link.springer.com/article/10.1208/s12248-023-00845-y?error=cookies_not_supported&code=e2b30916-fcbf-4944-8c5a-e9a0915ba524
The impact of lactoferrin with different levels of metal saturation on the intestinal epithelial barrier function and mucosal...The impact of lactoferrin with different levels of metal saturation on the intestinal epithelial barrier function and mucosal...
Diet supplementation with Lf leads to neutralization of microbial antigens (namely LPS) in the intestinal lumen and a reduced ... Lactoferrin was also able to neutralize microbial-derived antigens, thereby potentially reducing their pro-inflammatory effect ... they also suggest that the anti-inflammatory activity of Lf is not as potent when a more complex mixture of bacterial antigens ... mucous layer results in a loss of intestinal integrity and the translocation of microorganisms and microbial-derived antigens ...
https://link.springer.com/article/10.1007/s10534-016-9973-x
Characterisation of Stramenopile-specific mastigoneme proteins in Phytophthora parasitica | ProtoplasmaCharacterisation of Stramenopile-specific mastigoneme proteins in Phytophthora parasitica | Protoplasma
Cope M, Hardham A (1994) Synthesis and assembly of flagellar surface antigens during zoosporogenesis in Phytophthora cinnamomi ... DAmico F, Skarmoutsou E, Stivala F (2009) State of the art in antigen retrieval for immunohistochemistry. J Immunol Methods ...
https://link.springer.com/article/10.1007/s00709-018-1314-1?error=cookies_not_supported&code=41d67d8c-3607-423c-a9f7-691c5312122a
Advances in the Pathogenesis of Auto-antibody-Induced Cerebellar Synaptopathies | The CerebellumAdvances in the Pathogenesis of Auto-antibody-Induced Cerebellar Synaptopathies | The Cerebellum
Table 1 Auto-antibodies toward ion channel- and synapse-related antigens commonly found in immune-mediated cerebellar ataxias ... Since GAD65 is assumed to be exposed during exocytosis, anti-GAD65 Ab have access to this antigen. Anti-GAD65 Ab disturbs the ... The cytotoxic T cell-mediated killing of tumor cells releases additional cancer antigens, resulting in the continuity of the ... Notably, some of these antigens are involved in cerebellar synaptic transmissions, which include glutamic acid decarboxylase 65 ...
https://link.springer.com/article/10.1007/s12311-021-01359-z
Impact of PSA flare-up in patients with hormone-refractory prostate cancer undergoing chemotherapy | SpringerLinkImpact of PSA flare-up in patients with hormone-refractory prostate cancer undergoing chemotherapy | SpringerLink
The intention of this study is to describe the impact and underlying potential basis of the prostate-specific antigen (PSA) ... Kelly WK, Scher HI, Mazumdar M et al (1993) Prostate-specific antigen as a measure of disease outcome in metastatic hormone- ... The intention of this study is to describe the impact and underlying potential basis of the prostate-specific antigen (PSA) ... Olbert PJ, Hegele A, Kraeuter P et al (2006) Clinical significance of a prostate-specific antigen flare phenomenon in patients ...
https://link.springer.com/article/10.1007/s11255-007-9221-y?error=cookies_not_supported&code=b26673a1-065b-4bc1-9e5a-572e39238db7
Pre-clinical blocking of PD-L1 molecule, which expression is down regulated by NF-κB, JAK1/JAK2 and BTK inhibitors, induces...Pre-clinical blocking of PD-L1 molecule, which expression is down regulated by NF-κB, JAK1/JAK2 and BTK inhibitors, induces...
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol. mai 1996;8(5):765-72. ...
https://link.springer.com/article/10.1186/s12964-019-0391-x
Evolving Role of Vitamin D in Immune-Mediated Disease and Its Implications in Autoimmune Hepatitis | SpringerLinkEvolving Role of Vitamin D in Immune-Mediated Disease and Its Implications in Autoimmune Hepatitis | SpringerLink
Regulation of human monocyte HLA-DR and CD4 antigen expression, and antigen presentation by 1,25-dihydroxyvitamin D3. Blood. ... Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease. Clin Exp Immunol. ... Vitamin D controls T cell antigen receptor signaling and activation of human T cells. Nat Immunol. 2010;11:344-349. ...
https://link.springer.com/article/10.1007/s10620-018-5351-6?error=cookies_not_supported&code=6475bd1b-5d51-42ac-b16a-93df0268662b
Expanding roles for leukotrienes in airway inflammation | SpringerLinkExpanding roles for leukotrienes in airway inflammation | SpringerLink
Islam SA, Thomas SY, Hess C, et al.: The leukotriene B4 lipid chemoattractant receptor BLT1 defines antigen-primed T cells in ... A novel role of cysteinyl leukotrienes to promote dendritic cell activation in the antigen-induced immune responses in the lung ... on lung inflammation produced by segmental antigen challenge in human beings. J Allergy Clin Immunol 1996, 97:646-654. ...
https://link.springer.com/article/10.1007/s11882-008-0057-z?error=cookies_not_supported&code=a0891d6c-71a5-46cd-84d6-cda2a6c5bc4c
Sequencing technologies and genome sequencing | Journal of Applied GeneticsSequencing technologies and genome sequencing | Journal of Applied Genetics
2010) Next-generation sequencing: the solution for high-resolution, unambiguous human leukocyte antigen typing. Hum Immunol 71: ...
https://link.springer.com/article/10.1007/s13353-011-0057-x
Comparison of transplastomic Chlamydomonas reinhardtii and Nicotiana tabacum expression system for the production of a...Comparison of transplastomic Chlamydomonas reinhardtii and Nicotiana tabacum expression system for the production of a...
Watson J, Koya V, Leppla SH, Daniell H (2004) Expression of Bacillus anthracis protective antigen in transgenic chloroplasts of ... Daniell H, Singh ND, Mason H, Streatfield SJ (2009) Plant-made vaccine antigens and biopharmaceuticals. Trends Plant Sci 14:669 ...
https://link.springer.com/article/10.1007/s00253-017-8164-1?error=cookies_not_supported&code=88325a08-b4f6-4a51-b486-803a776747d0
An update on the aspects of Zika virus infection on male reproductive system | SpringerLinkAn update on the aspects of Zika virus infection on male reproductive system | SpringerLink
Sensitive detection of Zika virus antigen in patients whole blood as an alternative diagnostic approach. J Infect Dis. 2017; ...
https://link.springer.com/article/10.1007/s10815-019-01493-y?error=cookies_not_supported&code=afdfd2c6-91f3-4664-9fd1-9f2f7d1308d8
Biological responses of T cells encapsulated with polyelectrolyte-coated gold nanorods and their cellular activities in a co...Biological responses of T cells encapsulated with polyelectrolyte-coated gold nanorods and their cellular activities in a co...
Roncarolo M-G, Battaglia M (2007) Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. ...
https://link.springer.com/article/10.1007/s13204-017-0605-8
An Experimental Study Comparing the Expansion of Peripheral Blood Natural Killer (NK) Cells Cultured with Artificial Antigen...An Experimental Study Comparing the Expansion of Peripheral Blood Natural Killer (NK) Cells Cultured with Artificial Antigen...
NK expansion and activation were stimulated by culture with artificial antigen-presenting cells (aAPCs) and IL-2, in the ... An Experimental Study Comparing the Expansion of Peripheral Blood Natural Killer (NK) Cells Cultured with Artificial Antigen- ... 2014). Donor-derived natural killer cells infused after human leukocyte antigen-haploidentical hematopoietic cell ... Cells Cultured with Artificial Antigen-Presenting Cells, in the Presence or Absence of Bone Marrow Mesenchymal Stem Cells (MSCs ...
https://link.springer.com/article/10.1007/s12033-020-00250-2?error=cookies_not_supported&code=e16e305d-9ffd-4c40-ae3c-ebc7db7e9706
NPD1 Plus RvD1 Mediated Ischemic Stroke Penumbra Protection Increases Expression of Pro-homeostatic Microglial and Astrocyte...NPD1 Plus RvD1 Mediated Ischemic Stroke Penumbra Protection Increases Expression of Pro-homeostatic Microglial and Astrocyte...
H2-D1, involved in antigen processing and presentation, participates in synapse alterations and reflects neurotoxic astrocyte ...
https://link.springer.com/article/10.1007/s10571-023-01363-3
Adverse Drug Effects and Their Clinical Management: A Personal View | Drug SafetyAdverse Drug Effects and Their Clinical Management: A Personal View | Drug Safety
The HLA-B*1502 antigen for this serious adverse drug reaction is particularly prevalent in the Han Chinese population [8]. This ...
https://link.springer.com/article/10.1007/s40264-014-0167-6?error=cookies_not_supported&code=25d0c15c-1455-4347-aa6f-be4f9791c4e1
A systematic review of dietary, nutritional, and physical activity interventions for the prevention of prostate cancer...A systematic review of dietary, nutritional, and physical activity interventions for the prevention of prostate cancer...
Collette L, Burzykowski T, Schroder FH (2006) Prostate-specific antigen (PSA) alone is not an appropriate surrogate marker of ... prostate-specific antigen (PSA)] and clinical measures of prostate cancer progression (metastases, recurrence, disease-free ... A phase II study of pomegranate extract for men with rising prostate-specific antigen following primary therapy. J Clin Oncol ... Effects of a diet rich in phytoestrogens on prostate-specific antigen and sex hormones in men diagnosed with prostate cancer. ...
https://link.springer.com/article/10.1007/s10552-015-0659-4
Modulation of natural killer activity by thymosin alpha 1 and interferon | SpringerLinkModulation of natural killer activity by thymosin alpha 1 and interferon | SpringerLink
Hurme M, Sihvola M (1984) High expression of the Thy-1 antigen on natural killer cells recently derived from bone marrow. Cell ...
https://link.springer.com/article/10.1007/BF00205574?error=cookies_not_supported&code=b67cfba8-d04a-4960-b401-541f223217b1
A next generation mathematical model for the in vitro to clinical translation of T-cell engagers | Journal of Pharmacokinetics...A next generation mathematical model for the in vitro to clinical translation of T-cell engagers | Journal of Pharmacokinetics...
The key mechanism of action of TCEs is to crosslink CD3 on T cells and tumor associated antigens (TAAs) on tumor cells. The ... Leveraging a physiologically-based quantitative translational modeling platform for designing B cell maturation antigen- ...
https://link.springer.com/article/10.1007/s10928-023-09846-y?error=cookies_not_supported&code=0de7bf11-1c1c-4907-ba50-58d4a9c27216
Risk factors for the recurrence of relapsing polychondritis | Arthritis Research & TherapyRisk factors for the recurrence of relapsing polychondritis | Arthritis Research & Therapy
reported the cross-antigenicity of cartilage antigen and heat shock protein 60 from Mycobacterium tuberculosis, and William et ... cartilage antigens and mycobacterial heat-shock protein 60. Immunobiology. 2002;205:1-16. ...
https://link.springer.com/article/10.1186/s13075-022-02810-0
Multiplexed Biomolecular Detection Based on Single Nanoparticles Immobilized on Pneumatically Controlled Microfluidic Chip |...Multiplexed Biomolecular Detection Based on Single Nanoparticles Immobilized on Pneumatically Controlled Microfluidic Chip |...
Aptamer-antigen-antibody sandwiched detection scheme was utilized to enhance the LSPR responses for label-free biomolecular ... Hiep HM et al (2008) A microfluidic chip based on localized surface plasmon resonance for real-time monitoring of antigen- ... Guo LH, Kim DH (2012) LSPR biomolecular assay with high sensitivity induced by aptamer-antigen-antibody sandwich complex. ...
https://link.springer.com/article/10.1007/s11468-013-9661-4?error=cookies_not_supported&code=fdcb478a-28f8-4317-bcd5-957bed5cb42c
Chemically synthesized Gb3 glycosphingolipids: tools to access their function in lipid membranes | European Biophysics JournalChemically synthesized Gb3 glycosphingolipids: tools to access their function in lipid membranes | European Biophysics Journal
The globotriaosyl ceramide Gb3, also referred to as PK blood group antigen and CD77 (Johannes and Römer 2010), is the major ... Werz DB, Castagner B, Seeberger PH (2007) Automated synthesis of the tumor-associated carbohydrate antigens Gb-3 and Globo-H: ... Werz DB, Seeberger PH (2005) Total synthesis of antigen bacillus anthracis tetrasaccharide-creation of an anthrax vaccine ...
https://link.springer.com/article/10.1007/s00249-020-01461-w?wt_mc=Internal.Event.1.SEM.ArticleAuthorOnlineFirst
Minimal information about T cell assays: the process of reaching the community of T cell immunologists in cancer and beyond |...Minimal information about T cell assays: the process of reaching the community of T cell immunologists in cancer and beyond |...
... and quality of antigen-specific T cell responses are currently applied in human medicine. In most cases, assay ... Many assays to evaluate the nature, breadth, and quality of antigen-specific T cell responses are currently applied in human ... Comparison of cytokine elispot assay formats for the detection of islet antigen autoreactive t cells. Report of the third ... a two-step approach to harmonize the enumeration of antigen-specific CD8+ T lymphocytes by structural and functional assays. ...
https://link.springer.com/article/10.1007/s00262-010-0940-z
Vitamin D and its role in psoriasis: An overview of the dermatologist and nutritionist | Reviews in Endocrine and Metabolic...Vitamin D and its role in psoriasis: An overview of the dermatologist and nutritionist | Reviews in Endocrine and Metabolic...
... chemotaxis and antigen presentation seem to be dampened, and hydrogen peroxide secretion in human monocytes is also activated ... a phenotype of T cells promoting tolerance and inhibiting immunity after stimulation with antigen. Moreover, vitamin D induces ... antigen presentation, cell proliferation, increasing vascular permeability, angiogenesis and wound healing [30]. ...
https://link.springer.com/article/10.1007/s11154-017-9411-6
Journal of Materials Science: Materials in Medicine | HomeJournal of Materials Science: Materials in Medicine | Home
Yamada in consideration of the following 2021 article: "In vitro assessment of antitumor immune responses using tumor antigen ...
https://link.springer.com/journal/10856?error=cookies_not_supported&code=94b5ebc5-046e-4ad4-ac49-c9f39fe855df
Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues | DiabetologiaAdipose tissue plasticity: how fat depots respond differently to pathophysiological cues | Diabetologia
... when additionally selected for the cell surface marker MSC antigen 1 they showed potential to become both white and beige in ...
https://link.springer.com/article/10.1007/s00125-016-3933-4