... mediates the ATP-dependent membrane transport of glutathione S-conjugates and additional a ... We have previously shown that the multi-drug resistance protein (MRP) ... We have previously shown that the multi-drug resistance protein (MRP) mediates the ATP-dependent membrane transport of ... glutathione S-conjugates and additional amphiphilic organic anions. In the present study we demonstrate the expression of MRP ...
Organic Anion Transporting Polypeptide *ORL1 Receptors *Ornithine Decarboxylase *Orphan 7-TM Receptors ... p53 protein was synthesised at 30C for 1.5 hours. currently in medical tests function to promote apoptosis in malignancy cells ... p53 protein was synthesised at 30C for 1. Other Wnt Signaling by icem2012 ... N-Cadherin is area of the cadherin adhesion proteins superfamily and it is involved with cell migration during nervous program ...
Solute carrier organic anion transporter family member 1A2. 0.9860. 9. ERMN. Ermin. 0.9860. 9. ... Sodium/potassium transporting ATPase interacting 2. 0.9860. 9. SHTN1. Shootin 1. 0.9860. 9. ... RNA AND PROTEIN EXPRESSION SUMMARYi Below is an overview of RNA and protein expression data generated in the Human Protein ... Protein evidencei Evidence score for genes based on UniProt protein existence (UniProt evidence); neXtProt protein existence ( ...
Breast Cancer Resistance Protein Inhibitors. *. Organic Anion Transporting Polypeptide 1B3 Inhibitors. *. Organic Anion ...
Organic Anion Transport Polypeptides use Organic Anion Transporters. Organic Anion Transport Protein 1 ...
Organic Anion Transport Polypeptides use Organic Anion Transporters. Organic Anion Transport Protein 1 ...
... and transport (e.g., solute carrier family 9 member 9 [SLC9A9], solute carrier organic anion transporter family member 3A1 [ ... J. Sun and Z. Zhao, "A comparative study of cancer proteins in the human protein-protein interaction network," BMC Genomics, ... investigating the interactions between proteins encoded by the candidate genes in the human protein-protein interaction (PPI) ... C. C. Friedel and R. Zimmer, "Inferring topology from clustering coefficients in protein-protein interaction networks," BMC ...
Disrupting electron transport. *Generating a superoxide anion. *And inactivating bacterial oxidative defenses ... The researchers used proteomics-a technique that measures protein levels in a cell-and computer modeling to see granzyme Bs ... "Granzyme B Disrupts Central Metabolism and Protein Synthesis in Bacteria to Promote an Immune Cell Death ProGram." Cell (2017 ... "Granzyme B Disrupts Central Metabolism and Protein Synthesis in Bacteria to Promote an Immune Cell Death ProGram." Cell (2017 ...
... whereas deregulation of multidrug resistance-associated proteins was more variable, probably mainly reflecting secondary ... BSEP, Na+-taurocholate cotransporting polypeptide, and organic anion transporting polypeptide B were downregulated with most ... BSEP, Na+-taurocholate cotransporting polypeptide, and organic anion transporting polypeptide B were downregulated with most ... cholestatic and some noncholestatic drugs, whereas deregulation of multidrug resistance-associated proteins was more variable, ...
N2 - Members of the leucine-rich repeat-containing 8 (LRRC8) protein family, composed of the five LRRC8A-E isoforms, are pore- ... LRRC8A and at least one of the other LRRC8 isoforms assemble into heteromers to generate VRAC transport activities. Despite the ... AB - Members of the leucine-rich repeat-containing 8 (LRRC8) protein family, composed of the five LRRC8A-E isoforms, are pore- ... Members of the leucine-rich repeat-containing 8 (LRRC8) protein family, composed of the five LRRC8A-E isoforms, are pore- ...
The cyanobacterial bicarbonate transport protein, CmpA, selectively binds bicarbonate over other forms of dissolved inorganic ... Here, we outline a proposal to study an immobilized protein model for facilitating anion exchange within an eDAC system. ... transported across the membrane over the charge transported, bicarbonate selectivity is paramount to efficiency, as divalent ... CmpA, a cyanobacterial membrane protein, binds bicarbonate with a high selectivity over other forms of DIC.(3) Additionally, ...
... challenged with three different model proteins. All proteins were prepared as 1 g/L solutions in 50 mM phosphate buffer at pH ... Because of the generally high isoelectric points of MAbs, anion exchange (AEX) resins are typically used as a polishing step in ... In contrast, a disposable membrane chromatography device has a convective mode of mass transport, which allows operation at ... The protein of interest was produced at Percivia, LLC, using the PER.C6 cell line in a fed-batch process with a chemically ...
... process characterised by drastic changes in microglial morphology and by marked upregulation of the 18-kDa translocator protein ... and anion transport, (3) porphyrin binding and transport for heme synthesis, and (4) regulation of mitochondrial function and ... cholesterol binding and transport into mitochondria, a key function in steroidogenesis and bile salt synthesis, (2) protein ... including the isoquinolone binding protein of 18 kDa (TSPO), a voltage-dependent anion channel of 32 kDa (VDAC) and an adenine ...
In the kidney OAT1 and OAT3 make use of a tertiary transport mechanism to move organic anions across the basolateral membrane ... PKC-induced direct phosphorylation has been reported for other membrane proteins yet our results showed that a range of PKC ... This cascade of events indirectly links organic anion transport to metabolic energy and the Na+ gradient allowing the entry ... Morin hydrate by a dicarboxylate/organic anion exchanger-namely OAT-to move the organic anion substrate into the cell. ...
Norepinephrine Plasma Membrane Transport Proteins. *Organic Anion Transport Protein 1. *Organic Cation Transport Proteins ... Amino Acid Transport System y+L*Amino Acid Transport System y+L ... Amino Acid Transport System y+. *Amino Acid Transport System y+ ... "Amino Acid Transport System y+L" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... This graph shows the total number of publications written about "Amino Acid Transport System y+L" by people in this website by ...
The protein encoded by this gene is part of the anion exchanger (AE) family and is expressed in the erythrocyte plasma membrane ... where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein ... Predicted intracellular proteins. Predicted membrane proteins. Protein evidence (Ezkurdia et al 2014). Protein evidence (Kim et ... Protein family. Blood group antigen proteins. CD markers. Disease related genes. Human disease related genes. Mapped to ...
Norepinephrine Plasma Membrane Transport Proteins. *Organic Anion Transport Protein 1. *Organic Cation Transport Proteins ... Plasma Membrane Neurotransmitter Transport Proteins [D12.776.157.530.562.374]. *Serotonin Plasma Membrane Transport Proteins [ ... Plasma Membrane Neurotransmitter Transport Proteins [D12.776.543.585.562.374]. *Serotonin Plasma Membrane Transport Proteins [ ... Serotonin Plasma Membrane Transport Proteins [D12.776.157.530.450.625.311]. *Neurotransmitter Transport Proteins [D12.776. ...
Norepinephrine Plasma Membrane Transport Proteins. *Organic Anion Transport Protein 1. *Organic Cation Transport Proteins ... "Glucose Transport Proteins, Facilitative" by people in this website by year, and whether "Glucose Transport Proteins, ... "Glucose Transport Proteins, Facilitative" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus ... Below are the most recent publications written about "Glucose Transport Proteins, Facilitative" by people in Profiles. ...
Band 3 anion transport protein、 Band 4.1-like protein 1、 Band 4.1-like protein 5、 Basal cell adhesion molecule、 Basement ... Bcl-2-like protein 1、 Bcl-2-like protein 1(Bcl2-L-1)、 Bcl-2-like protein 11、 Bcl-2-like protein 2(Bcl2-L-2)、 Bcl-2-related ... B-cell linker protein、 B-cell lymphoma 3 protein、 B-cell lymphoma 3 protein(BCL-3)、 B-cell lymphoma 6 protein、 B-cell lymphoma/ ... bone morphogenetic protein 15、 bone morphogenetic protein 2、 bone morphogenetic protein 4、 bone morphogenetic protein 4 、 bone ...
The OM may be the 1st barrier-imported proteins that tRNAs encounter while they may be being transported in to the ... Presently, just four mitochondrial OM protein are known in trypanosomatids. They are the voltage-dependent anion route (VDAC) ... 40 proteins talk about homology with proteins of known features. The function of 42 protein, 33 which are particular to ... 40 proteins talk about homology with proteins of known features. The function of 42 protein, 33 which are particular to ...
We cloned Xenopus monocarboxylate transporter 8 (mct8) and organic anion-transporting polypeptide 1C1 (oatpc1c1), focusing on ... Protein alignment and bootstrap analysis showed that Xenopus mct8 and oatp1c1 are closer to their mammalian orthologs than ... Again similar to humans, Xenopus oatp1c1 transported T4 but not T3, MIT, or DIT. We used reverse transcription quantitative ... Xenopus mct8 was found to actively transport both T3 and T4 bidirectionally. As to the thyroid precursor molecules, ...
... or organic anion transporting polypeptide (OATP)1B1, OATP1B3, organic anion transporter (OAT)1, OAT3, organic cation ... Bosutinib may have the potential to inhibit breast cancer resistance protein (BCRP) in the gastrointestinal tract but has a low ... The high-fat meal (800-1000 total calories) consisted of approximately 150 protein calories, 250 carbohydrate calories, and 500 ... Protein binding of bosutinib is 94% in vitro and 96% ex vivo, and is independent of concentration. ...
It is a protein which transports many different kinds of compounds out of cells, for example from endocytes to the lumen with ... Organic Anion Transporting Polypeptide 2B1 (OATP2B1) is an influx transporter expressed widely throughout the body in tissues ... The double-transfected MDCKII cell line is a useful in vitro model of hepatic vectorial transport of organic anions in humans. ... These transporters are responsible for the vectorial transcellular hepatobiliary transport of various organic anions in humans ...
Unlike RAS, the C others of RIT and RIN have a simple city-to-city transport( CAAX, XXCC, or CXC) was for the phosphate of ... POLK and POLZ have in the receptor of proteins reused multiple to such anions by POLK. also to POLZ, POLK starts stress- ... members of WNT, also directed to as inorganic transports of transcription( CDG), are close increased changes linking Defects of ... several first proteins( VOC) can facilitate encoded in any major download transformation of surfaces signaling from a acid of ...
0015347 sodium-independent organic anion transmembrane transporter activity IBA GO:0007186 G protein-coupled receptor signaling ... 0006627 protein processing involved in protein targeting to mitochondrion IBA GO:0072488 ammonium transmembrane transport ... 0098656 monoatomic anion transmembrane transport AnnotationPropagation P GO:0008308 voltage-gated monoatomic anion channel ... 0015711 organic anion transport AnnotationPropagation P GO:0015347 sodium-independent organic anion transmembrane transporter ...
CLCN4 is part of a group of organellar (endosomes, lysosomal) transport proteins ... two kidney and inner ear CLC-K variants are ion channels expressed on the plasma membrane where they regulate anion transport, ... counter-transport cycle, disproving several previous models and proposed protein conformations. These 4 states or ... suggesting the latter can contribute a functional transport function if it forms a dimer with non-functional CLC3 proteins, ...
These proteins show similar domain architectures as known organelle-targeted expression regulators of the octotrico peptide ... Instead we identified several expanded groups of short chromatophore-targeted orphan proteins. Members of one of these groups ... Here we show by mass spectrometric analyses of enriched insoluble protein fractions that, unexpectedly, nucleus-encoded ... Here we show by mass spectrometric analyses of enriched insoluble protein fractions that, unexpectedly, nucleus-encoded ...
It transports I-, SCN-, ClO3- with an electrogenic stoichiometry of 2 Na+:1 anion. In contrast, ReO4- and ClO4- is transported ... TSH positively regulates NIS mRNA and protein expression and therefore iodide accumulation. Moreover, when TSH is present, NIS ... Apart from its well-known I- transport activity, NIS also mediates the translocation of other anions, including the ... In addition to I-, NIS also mediates the transport of other anions. Pseudohalides such as thiocyanate (SCN-), ...
A knowledgebase for bio-chemical transformations and transport reactions ... The SLC26/SulP (solute carrier/sulphate transporter) proteins are a ubiquitous superfamily of secondary anion transporters. ... our data suggest that DauA is a protein with transport and regulation activities. This is the first report that a SLC26/SulP ... The SLC26/SulP (solute carrier/sulphate transporter) proteins are a ubiquitous superfamily of secondary anion transporters. ...