Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: can we trust congenic animals?
... ... congenic mice, we conducted the proper F2 controls and discovered significant differences between these F2 animals and MHC- ... Abstract Background Congenic strains of mice are assumed to differ only at a single gene or region of the genome. These mice ... Conclusions These data suggest that these strains differ for genes other than those in the MHC congenic region. The most likely ...http://journaldatabase.info/articles/infection-dependent_phenotypes.html