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*  MGI-Guidelines for Nomenclature of Mouse and Rat Strains
4.4 Recombinant Congenic Strains. 4.5 Advanced Intercross Lines. 5. Coisogenic, Congenic, and Segregating Inbred Strains. 5.1 ... When a mutant allele or chromosomal aberration is maintained by crossing animals bearing the mutation to an F1 hybrid at every ... 4.4 Recombinant Congenic Strains. Recombinant Congenic (RC) Strains are formed by crossing two inbred strains, followed by a ... 5.2 Congenic Strains. Congenic strains are produced by repeated backcrosses to an inbred (background) strain, with selection ...
http://www.informatics.jax.org/mgihome/nomen/strains.shtml
*  MGI-Rules and Guidelines for Nomenclature of Mouse and Rat Strains
5 Coisogenic, Congenic, and Segregating Inbred Strains. 5.1 Coisogenic Strains. 5.2 Congenic Strains. 5.3 Consomic Strains. 5.4 ... Such animals should be designated appropriately, according to the breeding scheme that produced them. 4.1 Recombinant Inbred ... 4.3 Recombinant Congenic Strains. Recombinant Congenic (RC) Strains are formed by crossing two inbred strains, followed by a ... 5.2 Congenic Strains. Congenic strains are produced by repeated backcrosses to an inbred (background) strain, with selection ...
http://www.informatics.jax.org/mgihome/nomen/2006_strains.shtml
*  003383 - 129S-Nog|tm1Amc|/J
... many animals on congenic background show increased ABR thresholds relative to wild-type mice; these animals hearing threshold ... Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, ... Animal Care and Use for SERVICES. Consistent with the requirement for a written understanding regarding animal care and use, ... the JACKSON Animal Care and Use Committee will review the animal care and use protocol(s) associated with any SERVICES to be ...
https://www.jax.org/strain/003383
*  007181 - B6.129X1-Notch1|tm2Rko|/GridJ
Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, ... Mutant mice were bred to C57BL/6J mice to generate this congenic strain. When maintaining the live congenic colony, mice may be ... Animal Care and Use for SERVICES. Consistent with the requirement for a written understanding regarding animal care and use, ... the JACKSON Animal Care and Use Committee will review the animal care and use protocol(s) associated with any SERVICES to be ...
https://www.jax.org/strain/007181
*  007561 - B6.129-Hif1a|tm3Rsjo|/J
Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, ... A speed congenic protocol was used for the first 6 generations of backcrossing, after which the mice were backcrossed an ... Animal Care and Use for SERVICES. Consistent with the requirement for a written understanding regarding animal care and use, ... the JACKSON Animal Care and Use Committee will review the animal care and use protocol(s) associated with any SERVICES to be ...
https://www.jax.org/strain/007561
*  000454 - WB.C3-Spta1|sph|/BrkJ
Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, ... In 1970 this congenic was at backcross generation N2, in 1976 it reached N9, in 1986 it reached N21 and was subsequently passed ... Animal Care and Use for SERVICES. Consistent with the requirement for a written understanding regarding animal care and use, ... the JACKSON Animal Care and Use Committee will review the animal care and use protocol(s) associated with any SERVICES to be ...
https://www.jax.org/strain/000454
*  000259 - JE/LeJ
Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, ... the espin actin-bundling proteins in the morphogenesis and stabilization of hair cell stereocilia revealed in CBA/CaJ congenic ... Animal Care and Use for SERVICES. Consistent with the requirement for a written understanding regarding animal care and use, ... the JACKSON Animal Care and Use Committee will review the animal care and use protocol(s) associated with any SERVICES to be ...
https://www.jax.org/strain/000259
*  Rederivation Service
Shipment includes a comprehensive animal health report. *Genotyping is available for an additional cost. ... Speed Congenic Service Speed Expansion Service Strain Rescue Service Genome Scanning Service ...
https://www.jax.org/jax-mice-and-services/breeding-and-rederivation-services/rederivation
*  MGI - Inbred Strains: C57BL
... towards the location of predisposing polygenes in quasi-congenic animal-models. Alcohol 13, 617-620. \par. Van Heyningen H. E ... in contrast with C57BL/10 and B10 congenic strains (Tam and Messner, 1996). C57BL/10. Congenic line B10.D2-n is highly ... Animal Sci. 45, 652-656. \par. Hoag W. G. (1963) Spontaneous cancer in mice. Ann. NY Acad. Sci. 108, 805-831. \par. Hoffman H. ... Animal Sci. 26, 781-787. \par. Curtis H. J. (1971) Genetic factors in aging. Adv. Genet. 16, 305-324. \par. Dagg C. P. (1966) ...
http://www.informatics.jax.org/inbred_strains/mouse/docs/C57BL.shtml
*  Gene-environment interaction: a significant diet-dependent obesity lo" by B York, A A. Truett et al.
... in congenic animals fed a low-fat chow diet (12 Kcal% fat). The congenic segment is approximately 25 cM in length, extending ... failed to show any differences between control and congenic animals. ... We were unable to show any significant difference between the energy intakes of the congenic and the control C57BL/6J mice on ... These results suggest that one or more genes present in the congenic segment modulate the susceptibility to fat deposition on ...
https://mouseion.jax.org/stfb1990_1999/1253/
*  6.4 TARGETED MUTAGENESIS AND GENE REPLACEMENT
It is the triple congenic 129/Sv-Sl/+, +c +p line produced by Stevens that acted as the founder for all '129 mice' that have ... By breeding the knock-out line with one of the transgenic lines, it becomes possible to generate a new line of animals in which ... The experiment is deemed a success if the ES cells successfully enter the germline of the chimeric animals as demonstrated by ... in male animals. As a means to better understand the genetic parameters responsible for tumor incidence, Stevens set out to ...
http://www.informatics.jax.org/silver/chapters/6-4.shtml
*  "Genetic background effects on age-related hearing loss associated with" by Kelly L Kane, Chantal M Longo-Guess et al.
... their 32 kHz ABR thresholds were significantly higher than those of CBA/CaJ and congenic strain mice by 6 months of age, and ... To determine the isolated effects of these alleles on different strain backgrounds, we produced the reciprocal congenic strains ... Acoustic Stimulation, Age Factors, Aging, Animals, Audiometry, Pure-Tone, Auditory Threshold, Cadherins, Cochlea, Disease ... To determine the isolated effects of these alleles on different strain backgrounds, we produced the reciprocal congenic strains ...
https://mouseion.jax.org/stfb2012/68/
*  Evidence for close linkage of a mouse light chain marker with the Ly-" by D M. Gibson, B A. Taylor et al.
B6.PL-Ly-2aLy-3a/Cy as well as in individual backcross animals of an incipient Ly-2a,3a congenic strain. Virtually complete ... 3a congenic line B6.PL-Ly-2aLy-3a/Cy as well as in individual backcross animals of an incipient Ly-2a,3a congenic strain. ...
https://mouseion.jax.org/stfb1970_1979/877/
*  "Mutation of Eif4g3, encoding a eukaryotic translation initiation facto" by Fengyun Sun, Kristina Palmer et al.
Animals, Cell Division, Cell Proliferation, Eukaryotic Initiation Factor-4G, Gene Expression Regulation, Developmental, HSP70 ... Heat-Shock Proteins, Infertility, Male, Male, Meiosis, Mice, Mice, Congenic, Mice, Inbred C3H, Mice, Inbred C57BL, Mice, ...
https://mouseion.jax.org/stfb2010/165/
*  "Replication of beta- and gammaretroviruses is restricted in I/LnJ mice" by L K. Case, L Petell et al.
Both types of responses were maintained in mice of the susceptible genetic background but congenic for the I/LnJ vic1 locus. ... To investigate whether I/LnJ mice resist infection with other retroviruses besides MMTV, the animals were infected with murine ... To investigate whether I/LnJ mice resist infection with other retroviruses besides MMTV, the animals were infected with murine ... Both types of responses were maintained in mice of the susceptible genetic background but congenic for the I/LnJ vic1 locus. ...
https://mouseion.jax.org/stfb2000_2009/1721/
*  000646 - A/J
Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, ... Genetic analysis of the construction of the AEJ.A congenic strain indicates that nonsyndromic CL(P) in the mouse is caused by ... Animal Care and Use for SERVICES. Consistent with the requirement for a written understanding regarding animal care and use, ... the JACKSON Animal Care and Use Committee will review the animal care and use protocol(s) associated with any SERVICES to be ...
https://www.jax.org/strain/000646
*  002023 - SWR.M-Emv21 Emv22/J
Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, ... SWR/J was made congenic for a pair of linked retroviral insertions, identified as Emv21 and Emv22, in the laboratory of Dr. ... Animal Care and Use for SERVICES. Consistent with the requirement for a written understanding regarding animal care and use, ... the JACKSON Animal Care and Use Committee will review the animal care and use protocol(s) associated with any SERVICES to be ...
https://www.jax.org/strain/002023
*  000461 - B10.D2-Hc|0| H2|d| H2-T18|c|/oSnJ
This congenic strain has been used for numerous immunological studies. ... Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, ... the H2 locus along with the Hc and H2-T18 loci from DBA/2 were selected in this congenic strain. ... Animal Care and Use for SERVICES. Consistent with the requirement for a written understanding regarding animal care and use, ...
https://www.jax.org/strain/000461
*  Jul 16 Human and Mammalian Genetics and Genomics: The 58th McKusick Short Course
The Short Course includes a focus on understanding the molecular basis of genetic disease, animal models of disease, treatment ... the relationship of heredity to disease in experimental animals and humans the importance of molecular genetics in the ... The content of the annual Short Course focuses on three areas: an up-to-date presentation of genetics in experimental animals ... JAX-designed SNP panels are used to develop congenic lines in your lab, confirm strain identity, and monitor genetic quality. ...
https://www.jax.org/education-and-learning/education-calendar/2017/july/human-and-mammalian-genetics-and-genomics-the-58th-mckusick-short-course
*  "Adipogenesis is inhibited by brief, daily exposure to high-frequency, " by C T. Rubin, E Capilla et al.
Over 9 weeks, these same signals suppressed fat production by 22% in the C3H.B6-6T congenic mouse strain that exhibits ... Over 9 weeks, these same signals suppressed fat production by 22% in the C3H.B6-6T congenic mouse strain that exhibits ... Adipose-Tissue, Animals, Epididymis, Image-Processing-Computer-Assisted, Male, Mechanotransduction-Cellular, Mice-Inbred-C57BL ...
https://mouseion.jax.org/stfb2000_2009/1663/
*  C3B6-Tg(APP695)3Dbo/Mmjax
Animal Care and Use for SERVICES. Consistent with the requirement for a written understanding regarding animal care and use, ... Normal cognitive behavior in two distinct congenic lines of transgenic mice hyperexpressing mutant APP SWE. Neurobiol Dis 12(3 ... the JACKSON Animal Care and Use Committee will review the animal care and use protocol(s) associated with any SERVICES to be ... Animal Health Reports. Facility Barrier Level Descriptions Production of mice from cryopreserved embryos or sperm occurs in a ...
https://www.jax.org/strain/003375
*  A major gene affecting age-related hearing loss in C57BL/6J mice." by K R. Johnson, L C. Erway et al.
ABR test results and cochlear histopathology of aged progenitors of these congenic lines are presented. Ahl is the first gene ... Marker assisted selection was then used to produce congenic lines of C57BL/6J that contain different CAST-derived segments of ... Animal, Auditory-Threshold: ph, Chromosome-Mapping, Chromosomes-Human-Pair-10, Cochlea: pa, Evoked-Potentials-Auditory-Brain- ... Marker assisted selection was then used to produce congenic lines of C57BL/6J that contain different CAST-derived segments of ...
https://mouseion.jax.org/stfb1990_1999/1017/
*  Analysis of pleiotropism at the dominant white-spotting (W) locus of " by E N. Geissler, E C. McFarland et al.
... nine co-isogenic and one highly congenic with the C57BL/6J strain, reveals a wide variety of influences upon pigmentation, ... Animal, Female, Genetic-Complementation-Test, Hematopoiesis, Male, Mice, Mice-Mutant-Strains: ge, Mutation, Oogenesis, ... Characterization of the pleiotropic effects of ten new putative W locus mutations, nine co-isogenic and one highly congenic ...
https://mouseion.jax.org/stfb1980_1989/148/
*  016175 - C.B6-Clock|m1Jt|/J
Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, ... mice on a C57BL/6 congenic background exhibit prolonged activity periods compared with mice on a congenic BALB/cJ background ... Animal Care and Use for SERVICES. Consistent with the requirement for a written understanding regarding animal care and use, ... the JACKSON Animal Care and Use Committee will review the animal care and use protocol(s) associated with any SERVICES to be ...
https://www.jax.org/strain/016175
*  002105 - NZO/HlLtJ
Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, ... Leiter's research group at The Jackson Laboratory is currently developing a series of nine recombinant congenic strains (RCS) ... Animal Care and Use for SERVICES. Consistent with the requirement for a written understanding regarding animal care and use, ... the JACKSON Animal Care and Use Committee will review the animal care and use protocol(s) associated with any SERVICES to be ...
https://www.jax.org/strain/002105