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*  Complement factor b | definition of Complement factor b by Medical dictionary
2. in the alternative complement pathway, surface-bound C3b binds factor B, which is cleaved by factor D into Ba and Bb. C3bBb ... a test for hemophilia A; activity is measured in biologic assays using factor VIII-deficient plasma as the substrate. ... animal. See also transfer factor. ... When a complex of C3bBbC3b is formed, this is the alternative ... factor D a factor that when activated serves as a serine esterase in the alternative complement pathway. ...
http://medical-dictionary.thefreedictionary.com/Complement+factor+b
*  Eye Irritation Time-to-Toxicity
Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , Eye Irritation Time-to-Toxicity ... Modernization of EPA "6-Pack" of Acute Toxicity Tests Continues. *Tiered In Vitro Testing Strategy For Assessing The Ocular and ... Since test formulations can be applied topically at full formulation strength, tissue exposures occur just as they do in vivo. ... Please contact IIVS for more information on Ocular Screening and how it may be suitable for your organization's testing needs. ...
http://iivs.org/testing-services/assays/ocular/ocular-screening/
*  Trans-Epithial Permeability
Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , Assays Trans-Epithial Permeability ... to evaluate the potential ocular irritancy of a test article. Types of injury caused by exposure to the test article are ... The BCOP (Bovine Corneal Opacity and Permeability) assay is an in vitro eye irritation test method developed by Gautheron et al ... Corneal opacity... Assessing Corneal Recovery , CAMVA , Eye Irritation Test , NociOcular Eye Sting , Ocular Irritection , ...
http://iivs.org/assay/ocular/trans-epithial-permeability/
*  Skin Corrosion Test (OECD 431)
Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , Skin Corrosion Test (OECD 431) ... The In Vitro Skin Corrosion Test is an in vitro, non-animal test designed to identify those chemicals and mixtures capable of ... NOTE: since this test method does not discriminate among any non-corrosive categories, a non-corrosive prediction by this test ... Modernization of EPA "6-Pack" of Acute Toxicity Tests Continues. *Tiered In Vitro Testing Strategy For Assessing The Ocular and ...
http://iivs.org/testing-services/assays/dermal/skin-corrosion-test/
*  Oral - Gingival Screening
Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , Oral - Gingival Screening ... and they are dependent on the class of materials tested. Alternative assays that can be used to assess the toxicity of test ... The test systems use a serum-free medium, which eliminates the possibility of interaction between the serum protein and test ... The toxicity is expressed as ET50 values representing the exposure time to a test article that reduces the viability of the ...
http://iivs.org/testing-services/assays/mucosal/oral-screening/
*  Dermal
Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , Dermal. 521 page-template-default,page,page-id-521, ... The Skin Irritation Test (SIT) is an in vitro, non-animal test designed to identify those chemicals and mixtures capable... ... The In Vitro Skin Corrosion Test is an in vitro, non-animal test designed to identify those chemicals and mixtures... ... Skin Irritation Test (SIT, OECD 439). Skin Irritation Test (SIT) in a Reconstructed Human Epidermis (RhE) Model Skin Irritation ...
https://iivs.org/testing-services/assays/dermal/
*  IIVS BCOP Training Video - Portuguese
... minute video demonstrates how to perform the BCOP assay according to the Test Guidelines set forth for the assay by the ... Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , IIVS BCOP Training Video - Portuguese ... This 13- minute video demonstrates how to perform the BCOP assay according to the Test Guidelines set forth for the assay by ... focuses on steps that are critical to the success of the assay such as handling of the isolated cornea and removal of the test ...
http://iivs.org/2015/11/01/iivs-bcop-training-video-portuguese/
*  Ocular Screening
Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , Assays Ocular Screening ... Eye Irritation Test (EIT, OECD 492). August 24, 2016. The Eye Irritation Test (EIT) is an OECD-approved in vitro non-animal ... non-animal testing Strategies for Eye Irritation Testing. September 17, 2018. Determination of ocular irritation potential is a ... The FHSA does not specifically require animal testing be conducted to determine if a hazard is present, but historically many ...
https://iivs.org/assay/ocular/ocular-screening/
*  Irritation Screening
Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , Irritation Screening ... OECD Test Guideline 435: In Vitro Membrane Barrier Test Method for Skin Corrosion (TG 435), and OECD Test Guideline 439: In ... Modernization of EPA "6-Pack" of Acute Toxicity Tests Continues. *Tiered In Vitro Testing Strategy For Assessing The Ocular and ... the following validated test methods may be used to classify and label the skin irritation or corrosion hazards of test ...
http://iivs.org/testing-services/assays/dermal/irritation-screening/
*  Chronic Respiratory Toxicity
Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , Chronic Respiratory Toxicity ... Holger Behrsing, PhD, Participates in Round Table Discussion on Non-Animal Approaches for Inhalation Toxicology ... and the presence of increased numbers of activated macrophages can be a powerful tool in deciphering the effects of test ...
http://iivs.org/testing-services/assays/respiratory-toxicology/chronic-respiratory-toxicity/
*  Posters & Presentations
Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , NewsType Posters & Presentations ... Redefining Test Systems from Animals to Tissues and Beyond. August 28, 2017. The use of non-whole animal test methods ... Non-Animal Testing Approach to Address Biocompatibility Testing of Medical Devices Required by the United States Food and Drug ... when the vast majority of regulated research was performed using animals as the test system. Current innovative, alternative ...
http://iivs.org/newstype/posters-presentations/
*  Ocular
Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , Ocular. 533 page-template-default,page,page-id-533, ... The Eye Irritation Test (EIT) is an OECD-approved in vitro non-animal test method for identifying chemicals and mixtures that ... However, no current validated non-animal ocular irritation test methods or prediction tools are able to predict corneal ... The test method evaluates the cytotoxicity induced by a series of test chemical dilutions in a monolayer of rabbit corneal ...
https://iivs.org/testing-services/assays/ocular/
*  Assessing Corneal Recovery
Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , Assessing Corneal Recovery ... However, no current validated non-animal ocular irritation test methods or prediction tools are able to predict corneal ... Modernization of EPA "6-Pack" of Acute Toxicity Tests Continues. *Tiered In Vitro Testing Strategy For Assessing The Ocular and ... However, current validated in vitro ocular irritation test methods are designed to classify test materials based on ...
http://iivs.org/testing-services/assays/ocular/assessing-corneal-recovery/
*  Queen Mary University of London - Wikipedia
"Professorial chair to lead search for animal testing alternatives". Times Higher Education. 16 January 2013. Retrieved 20 ... In January 2013, Queen Mary established the world's first professorial chair in animal replacement science. From 2014, Queen ...
https://en.wikipedia.org/wiki/Queen_Mary_University_of_London
*  History of Queen Mary University of London - Wikipedia
"Professorial chair to lead search for animal testing alternatives". Times Higher Education. 16 January 2013. Retrieved 20 ... "Thurston's DH4 Tests". Retrieved 11 September 2011. "Spratt's". London Remembers. Retrieved 16 July 2015. "Information released ... In January 2013, Queen Mary established the world's first professorial chair in animal replacement science. From 2014, Queen ...
https://en.wikipedia.org/wiki/History_of_Queen_Mary_University_of_London
*  Frequently Asked Questions - Pro-Test Germany
Are there alternatives to animal testing?. A detailed discussion of this issue can be found on our page for alternatives to ... Computer simulations, microdoses, imaging techniques and in vitro tests are often cited as alternatives to animal testing. ... Exactly these considerations are also the reason why animal testing for basic research is permitted under the German animal ... Who cares about the welfare of lab animals?. Everyone who works with animals in the laboratory help to look after them. Animal ...
http://www.pro-test-deutschland.de/en/faq/
*  Blog | SciKon
We've made the CAATwalk news; Center for Alternatives to Animal Testing. Posted on: Feb. 18, 2016. in Uncategorized. ... technologies could be used by pharmaceutical companies to help weed out toxic drug candidates before they are tested in animals ... Title: Making sure chemical toxicity tests don't miss metabolites. Find It: Chemical & Engineering News, 94(32), August 08, ...
https://scikoninnovation.com/blog/
*  How We Can Finally End Cosmetic Testing On Animals - The Dodo
Moon Jeong-Lim launched a bill to ban the sale of newly animal tested cosmetics where non-animal alternative tests are ... Status: India banned animal testing of cosmetics, as well as the import of all newly animal tested cosmetics, in 2014. ... Status: The EU banned animal testing of cosmetics in 2009; and banned the sale of newly animal tested cosmetics in 2013. ... Wang YuMin at the Parliament in Taipei to launch a bill to ban cosmetics animal testing and the sale of animal-tested cosmetics ...
https://www.thedodo.com/ending-1106092222.html
*  Exotic Animal Medicine - review and test, 1e by - Free PDF - Page 12
1 Non-Animal Alternatives for Research and Testing under the ... Nov 1, 2016 ... testing, exhibition and transportation. .... ( ... Exotic Animal Medicine - review and test, 1e by - Free PDF - Page 12. Search results have 1000 titles, on 50 pages ... Animal Reiki Training and A Book Review, By Dr ... - Dr-Jordan.com special needs animals, is a model to which all sanctuaries ... Book Review: Vibration Testing: Theory and Practice - AIAA ARC Vibration Testing: Theory and Practice. Kenneth G. McConnell, ...
http://montgomeryhotrodbooks.com/related/exotic-animal-medicine-review-and-test-1e/page-11/
*  Marine biotoxins
The European Commission has recognised the needs of the analytical community to develop methods alternative to animal testing. ... LC-MS and immunoassays can be used as alternative or complementary methods to the biological testing methods, provided that ... The method is at best semi-quantitative (Hallegraeff et al., 1995 and Van Egmond et al., 1993). The test is still used ... The (starved) animals are fed with suspect shellfish tissue (mixed into the diet) and observed during 16 hours for signs of ...
http://www.fao.org/docrep/007/y5486e/y5486e0p.htm
*  A primer on systematic reviews in toxicology | SpringerLink
7.Center for Alternatives to Animal Testing at Johns Hopkins Bloomberg School of Public HealthBaltimoreUSA ... which is funded by Center for Alternatives to Animal Testing at Johns Hopkins Bloomberg School of Public Health and ExxonMobil ... For systematic reviews assessing the accuracy of a test method compared with another, one would need to specify an index test ... The potential of tissue engineering for developing alternatives to animal experiments: a systematic review. J Tissue Eng Regen ...
https://link.springer.com/article/10.1007%2Fs00204-017-1980-3
*  3D Cell Culture : Pharmaceuticals : UK
Helena Hogberg, Deputy Director, Center for Alternatives to Animal Testing, Johns Hopkins University Bloomberg School of Public ... Helena Hogberg, Deputy Director, Center for Alternatives to Animal Testing, Johns Hopkins University Bloomberg School of Public ... Deputy Director, Center for Alternatives to Animal Testing, Johns Hopkins University Bloomberg School of Public Health ... Growth in this market is also driven by global factors such as a need for alternative methods to animal resting, funding from ...
https://www.smi-online.co.uk/pharmaceuticals/uk/conference/3D-Cell-Culture?o=login&dl=br&p1=5278&p2=934
*  Grants & Funding
Program "Development of Alternative and Complementary Methods to Animal Testing" of the State of Baden-W├╝rttemberg. The State ... The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) wants to be a leading force in the development and use of 3R ... The Johns Hopkins Center for Alternatives to Animal Testing (CAAT). Funding (CAAT Grants Program) as well as awards. see entry ... The Johns Hopkins Center for Alternatives to Animal Testing (CAAT). Funding (CAAT Grants Program) as well as awards. see entry ...
https://www.invitrojobs.com/index.php/en/grants-funding
*  Syed Ziaur Rahman - Wikipedia
He even translated few papers into Urdu in the field of Alternatives to animal testing. Rahman also works in the field of ... Rahman's contributed in the area of Alternatives to animal testing. He believed in the philosophy of '3Rs" of Russell and Burch ... getting survey related to the attitude of undergraduate medical students towards Alternatives to animal testing and Animal ... a presentation by InterNICHE Co-ordinator Nick Jukes about alternatives to animal testing in education: Urdu Translation ...
https://en.wikipedia.org/wiki/Syed_Ziaur_Rahman