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*  Primary structure of guinea pig preprodynorphin and preproenkephalin mRNAs : multiple transcription initiation sites for...
These findings differ from those of previous rodent studies and suggest that this species may provide a useful alternative ... Human genetic studies were also conducted in opioid-dependent (formerly heroin-addicted) and control subjects to test the ... 1. Preproenkephalin Gene and mRNA: Studies of Structure, Function, Cocaine Responses in an Animal Model, and Genetic ... an animal that may have specific advantages for modeling the human endogenous opioid system. A guinea pig brain cDNA library ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:164133
*  Frontiers | Crosstalk between Receptor and Non-receptor Mediated Chemical Modes of Action in Rat Livers Converges through a...
Kleinjans, J. (2014). Toxicogenomics-Based Cellular Models: Alternatives to Animal Testing for Safety Assessment. Amsterdam: ... Animals were handled in accordance with The United States Department of Agriculture and Code of Federal Regulations Animal ... To infer which pathways are over-represented by the genes in the preserved modules, we performed an enrichment test using the ... This preservation is statistically assessed by a permutation test to derive of a summary Z score. The significant modules (Z_ ...
https://www.frontiersin.org/articles/10.3389/fgene.2017.00157/full?utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1
*  Foundation for Biomedical Research - Wikipedia
"The Johns Hopkins Center for Alternatives to Animal Testing (CAAT)". Retrieved 2009-06-24. PETA. "Animals in Experimentation - ... "Animal research and medical progress". About animal testing. "Scientists Against Animal Testing". The Society for Neuroscience ... Animal testing History of animal testing Foundation for Biomedical Research. "About FBR". Retrieved 2009-06-24. 2005 Report on ... Some animal rights supporters believe that alternatives exist for animal models in research; however the vast majority of ...
https://en.wikipedia.org/wiki/Foundation_for_Biomedical_Research
*  Research Paper: Animal Testing Negatives … | 7 Pages
Numerous studies by scientists and ethicists have shown that animal testing leads to pain, emotional distress,… ... Animal Testing Negatives' Research Paper (2261 Words)! ☘ if the researchers take utmost care to prevent them. ... "Animal Testing Alternatives Come Alive In U.S.." Nature Medicine 16.12 (2010): 1348. MEDLINE. Web. 7 May 2012.. Dove, Alan. " ... Animal Testing Animal Models Are Faulty Indicators Essay … Animal Testing. Animal models are faulty indicators and barriers in ...
https://www.essaytown.com/subjects/paper/animal-testing-negatives/97125
*  Novel Experimental System as an Alternative to Animal Experiments to Study the Skin Permeation of Drugs AATEX Vo1 14(2)
Animal Test. EXperiment.: Alternatives to Animal Testing and EXperimentation). ... Novel Experimental System as an Alternative to Animal Experiments to Study the Skin Permeation of Drugs Toshinobu Seki, Tatsuya ... permeation quantitatively and to imitate some events which can happen in inflamed tissues in skin without requiring animals. ...
http://www.asas.or.jp/jsaae/jsaae/aatex/14-2-3.html
*  Gene Expression Profiling of Embryonic Fibroblasts Derived from a Rat Model of Periodontal Disease AATEX Vol.11(1)
Animal Test. EXperiment.: Alternatives to Animal Testing and EXperimentation). ... we aimed to evaluate the utility of ODUS/Odu-derived cells as an alternative to animal models for biomedical research into ... Key words:animal model, periodontal disease, DNA microarray, gene expression profiling, embryonic fibroblast return. (AATEX: ... Osaka-Dental-University-Susceptible rats (ODUS/Odu) are a useful animal model for human periodontal disease. Through ...
http://www.asas.or.jp/jsaae/jsaae/aatex/11-1-10.html
*  Development of an Alternative Test for Skin Sensitization Using a Three-dimensional Human Skin Model Consisting of Dendritic...
Animal Test. EXperiment.: Alternatives to Animal Testing and EXperimentation) ... Development of an Alternative Test for Skin Sensitization Using a Three-dimensional Human Skin Model Consisting of Dendritic ... key words: skin sensitization test, 3D human skin model, collagen vitrigel membrane return. (AATEX: Altern. ... In order to study the possibility of applying an established test method to cosmetic products such as milky lotion and cream, ...
http://www.asas.or.jp/jsaae_old/aatex/16-1-1.html
*  Skin Sensitization Study by Quantitative Structure-Activity Relationships (QSAR) AATEX 14(3)
Animal Test. EXperiment.: Alternatives to Animal Testing and EXperimentation). ... Key wards: skin sensitization, QSAR, animal study, occupational exposure limit return. (AATEX: Altern. ... In silico assessment of skin sensitization is increasingly needed owing to the problems concerning animal welfare, as well as ... excessive time consumed and cost involved in the development and testing of new chemicals. Skin sensitization positive/negative ...
http://www.asas.or.jp/jsaae/jsaae/aatex/14-3-2.html
*  An in Vitro Evaluation Method to Test Ocular Irritation using a Human Corneal Epithelium Model AATEX Vo1 13(2)
Animal Test. EXperiment.: Alternatives to Animal Testing and EXperimentation). ... Recently, safety evaluation tests that do not involve animal experiments have been prosperously developing. However, the ... and found to correlate with the Draize eye test results. Key words: ocular irritation, corneal model, Draize eye test, ... An in Vitro Evaluation Method to Test Ocular Irritation using a Human Corneal Epithelium Model Shoko Arai1, Naoki Yamamoto2, ...
http://www.asas.or.jp/jsaae_old/aatex/13-2-5.html
*  Assessment of the in vitro skin irritaion by chemicals using the Vitrolife-Skin TM human skin model AATEX Vo1 13(1)
Animal Test. EXperiment.: Alternatives to Animal Testing and EXperimentation). ... Vitrolife-SkinTM showed a basic utility for irritancy testing by this method and it is possible to confidently predict skin ... The European Centre for the Validation of Alternative Methods (ECVAM) is currently supporting formal validation studies of in ... vitro tests for predicting skin irritancy and corrosivity, including tests employing two human skin models, EPISKINTM and ...
http://www.asas.or.jp/jsaae_old/aatex/13-1-2.html
*  Animals in culture - Wikipedia
ISBN 978-0-8247-5496-9. Doke, Sonali K.; Dhawale, Shashikant C. (July 2015). "Alternatives to animal testing: A review". Saudi ... are hybrid animals; the name zodiac indeed means a circle of animals. All twelve signs of the Chinese zodiac are animals. " ... Animals serve as models in biological research, such as in genetics, and in drug testing. Many species are kept as pets, the ... Animals, and products made from them, are used to assist in hunting. People have used hunting dogs to help chase down animals ...
https://en.wikipedia.org/wiki/Animals_in_culture
*  Living things in culture - Wikipedia
ISBN 978-0-8247-5496-9. Doke, Sonali K.; Dhawale, Shashikant C. (July 2015). "Alternatives to animal testing: A review". Saudi ... are hybrid animals; the name zodiac indeed means a circle of animals. All twelve signs of the Chinese zodiac are animals. ... Many animals are hunted for sport. The aquatic animals most often hunted for sport are fish, including many species from large ... Both animals and plants are significant in art, whether as background or as main subjects. Animals, often mammals but including ...
https://en.wikipedia.org/wiki/Living_things_in_culture
*  IFSCC Probes into the Biology of Cosmetics
... who covered the alternatives to animal testing currently available. He noted that the testing ban is expected to be put into ... cosmetic safety including consumer health and animal testing alternatives; neurobiology and immune response in cosmetics; and ... "it is unlikely that we will have fully replaceable test methods for animals in place by 2009 or 2013." The day's sessions ...
http://www.cosmeticsandtoiletries.com/networking/eventcoverage/34409834.html?page=3
*  The Development and Characterisation of a Structure-activity Relationship Model of the Draize Eye Irritation Test -...
... introduction and use of alternatives to laboratory animals in biomedical research and testing. ... FRAME, and has been a key scientific journal in the field of laboratory animal alternatives for more than 30 years. Circulated ... It covers the latest research relating to alternatives to the use of laboratory animals. Click here to learn about FRAME ... The Use of Transgenic Animals in the European Union The Use of Transgenic Animals in the European Union ...
http://www.atla.org.uk/the-development-and-characterisation-of-a-structure-activity-relationship-model-of-the-draize-eye-irritation-test/
*  Physicians Committee for Responsible Medicine - SourceWatch
PCRM promotes alternatives to animal testing. They have advocated to end gruesome experiments like Department of Defense (DOD) ... including a campaign to reduce animal use in toxicity testing.[27] See also animal testing, section 3 on product (toxicity) ... Al Gore's Deadly Animal Test Plan and the Scientist Who Can Stop It., PCRM Magazine, Spring 1999 ... Currently, more than three-quarters of all U.S. medical schools have discontinued animal testing for medical students. PCRM ...
https://sourcewatch.org/index.php/Physicians_Committee_for_Responsible_Medicine
*  Biosimulation - Wikipedia
In:The Economist (US) June 11, 2005 "Biograf 3R - Computational Alternatives to Animal Testing - Home". Biograf.ch. doi:10.1016 ... of reduction and replacement of animal experiments as well as to the refinement of the methodology in cases where animal tests ... In a future scenario, biosimulation would change the way substances are tested, in which in vivo and in vitro tests are ... The early prediction if a drug will fail in animals or humans would be a key to reduce both drug development costs and the ...
https://en.wikipedia.org/wiki/Biosimulation
*  In Vitro Lung Model Market by Type & Application - 2023 | MarketsandMarkets
4.2.1 Growing Focus on Developing Alternatives for Animal Testing Models 4.2.2 Technological Advancements and the Development ... The key factors driving the growth of this market include growing focus on developing alternatives for animal testing models, ... European Union Reference Laboratory for alternatives to animal testing (EURL-ECVAM), European Lung Foundation, Annual Reports, ...
https://www.marketsandmarkets.com/Market-Reports/lung-in-vitro-model-market-78042820.html
*  Human Liver Models Market by Drug Discovery Platform & Region - 2022 | MarketsandMarkets
Animal Models, 3D Bioprinting), and Region (North America, Europe, Asia Pacific, Rest of the World) & Geography ... 1.2.1.1 Growing Focus on Developing Alternatives for Animal Testing Models. 1.2.1.2 Significant Increase in Research Funding ... growth of this market is primarily driven by factors such as the growing focus on developing alternatives for animal testing ... 3.1.4 Animal Models. 3.1.5 3D Bioprinting. 4 Geographic Assessment (Page No. - 27). 4.1 Introduction 4.2 North America 4.2.1 US ...
https://www.marketsandmarkets.com/Market-Reports/human-liver-model-market-171046468.html
*  Using artificial intelligence to develop and test new drugs - Citizens for Alternatives to Animal Research
Citizens for Alternatives to Animal Research (CAARE), is a 501(c)(3) non-profit organization, established to highlight and ... The bottom line: Some 95% of drugs fail to be deemed safe or effective for human use due to misleading test results from animal ... "Basically one of the reasons why there is such a decline in research and development is because animal testing is not very ... We are using artificial intelligence technologies and in silico methods instead of animal testing to simulate and predict drug ...
http://www.caareusa.org/using_artificial_intelligence_to_develop_and_test_new_drugs
*  Updated NIOSH Guidance - Respirators and Facial Hair | Environmental Resource Center
Additional "Finding Information about Alternatives to Animal Testing" content. *Microphysiological Systems as used in "tissue ... OSHA's Fit Testing Procedures, 29 CFR 1910.134 Appendix A, Part I, (A)(9), states "The test shall not be conducted if there is ... Escape-only types of air purifying respirators are not required by OSHA to be fit tested, but special care must be exercised ... OSHA and ANSI Z88.10-2010 prohibit fit testing respirators when facial hair is at the sealing surface of the respirator. ...
https://www.ercweb.com/tips/show/updated-niosh-guidance-Respirators-and-facial-hair
*  General election manifesto 2001 [Archive]
... and end unnecessary repetitive tests. We will fund research into alternatives to animal testing. We believe that farm animals ... Reduce testing of the youngest school children. We will scrap testing ( SATs ) at age 7, while keeping it for older pupils. ... we are committed to strengthening animal welfare. We will establish an Animal Protection Commission to strengthen animal ... We will end the use of animals in the development and testing of weapons and household goods, ...
http://politicsresources.net/area/uk/e01/man/libdem/Fed2001.htm