Loading...
*  Primary structure of guinea pig preprodynorphin and preproenkephalin mRNAs : multiple transcription initiation sites for...
These findings differ from those of previous rodent studies and suggest that this species may provide a useful alternative ... Human genetic studies were also conducted in opioid-dependent (formerly heroin-addicted) and control subjects to test the ... 1. Preproenkephalin Gene and mRNA: Studies of Structure, Function, Cocaine Responses in an Animal Model, and Genetic ... an animal that may have specific advantages for modeling the human endogenous opioid system. A guinea pig brain cDNA library ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:164133
*  The Principles of Humane Experimental Technique: Preface
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... Many animals are used as sources of blood for complement fixation tests or the procedurally identical Wasserman Reaction. These ... The guinea pig, a numerically important animal, calls for more thought. There was a simple test to apply, and I applied it. ( ... Ratio of number of animals used for inoculation of milk or pathological specimens for TB to total number of animals used for ...
http://altweb.jhsph.edu/pubs/books/humane_exp/chap3d
*  Report and Recommendations Concerning the Procurement and Use of Antibodies at Northwestern University
The following paper was prepared in response to inquiries made by representatives from two animal rights organizations ... the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... 4 John McArdle, Alternatives to Ascites Production of Monoclonal Antibodies, Animal Welfare Information Center, Vol. 8, no. 304 ... involve no animals and thus raise no ethical concerns; and 3) eliminate the problem of animal to human translation. rAbs can be ...
http://altweb.jhsph.edu/news/2015/antibodies_proposal.html
*  Altweb: Publications: Articles: Reducing Animal Research at the U.S. Army Medical Research Institute of Chemical Defense
... the-art of non-animal test development and validation and the potential for the possible incorporation of alternative tests ... an alternative? Opponent's statement. Developments in Animal and Veterinary Sciences, Vol. 27, Animal Alternatives, Welfare and ... an alternative? Proponent's statement. Developments in Animal and Veterinary Sciences, Vol. 27, Animal Alternatives, Welfare ... The use of transgenic animals in toxicity testing could lead to reduction and refinement in existing in vivo test protocols ( ...
http://altweb.jhsph.edu/pubs/ecvam/ecvam28.html
*  Altweb: Acronyms
The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) has developed a new online course, "Enhancing Humane Science ... IACUCs and Animal Ethics Committees RESOURCES. Resources for searching for alternatives, of particular interest to ... Information Resources for Animal Welfare and Alternatives: Institutional Care and Use Committees and their Administration ( ... Guidelines for the Euthanasia of Nondomestic Animal. Resources for "Lay Members" of Ethics/Animal Care and Use Committees ( ...
http://altweb.jhsph.edu/iacucs.html
*  Altex Issue 30.2 (2013) Now Available
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... Uncertainty of testing methods - What do we (want to) know?. MAIN ARTICLES. Si Wang, René Houtman, Diana Melchers, Jac Aarts, ... Advanced tests for skin and respiratory sensitization assessment. SYMPOSIUM REPORT. Costanza Rovida, Isabella De Angelis, and ... Alternative in vitro methods to characterize the role of Endocrine Active Substances (EASs) in hormone-targeted tissues ...
http://altweb.jhsph.edu/altex/30_2/
*  May 14th Webinar on Regulatory Acceptance of Alternative Methods
... and Thomas Hartung of the Johns Hopkins Center for Alternatives to Animal Testing. The webinar will be presented on May 14, ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ... Building a Better Epithelium: Breaking the Barrier to the Next Generation of Toxicity Testing. March 10, 2018. San Antonio, TX ... May 14th Webinar on Regulatory Acceptance of Alternative Methods. The Mid-Atlantic Society of Toxicology will present a webinar ...
http://altweb.jhsph.edu/news/current/webinar_regulatory_acceptance
*  Altweb: Special Section on Refinement: Pain and Distress
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... The more variable the data, the more animals must be used, which will end up requiring more animals to be used in research8. ... Environmental enrichment also can lead to a reduction in the number of animals needed, since fewer animals may be lost during ... Animal Welfare Information Center (AWIC).. *Animal Welfare Information Center (AWIC) Bibliographies and Resource Guides & Other ...
http://altweb.jhsph.edu/resources/refinement/sections/enrichment.html
*  Altweb: Acronyms
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... ANIMAL USE STATISTICS. Canadian Council on Animal Care (CCAC): Facts and Figures on Animal Use in Canada ... USDA Animal and Plant Health Inspection Service (APHIS): Animal Welfare Reports. See "Annual Report of Enforcement" (appendices ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ...
http://altweb.jhsph.edu/statistics.html
*  ECEAE | The Truth About Cosmetics Animal Testing
What are the alternatives to animal testing?. There are a variety of approved alternatives that can replace cruel animal tests ... The finished product has not been tested on animals. * Cosmetic ingredients used to make that product have not been tested on ... Isn't cosmetics animal testing already banned?. After a 20-year campaign lead by the ECEAE and our partners, in March 2013, the ... What kinds of animal tests are carried out for cosmetics?. In cosmetics research, painful experiments are carried out worldwide ...
http://www.eceae.org/it/what-we-do/campaigns/cosmetics/the-truth-about-cosmetics-animal-testing
*  social discrimination test - Alternatives to Laboratory Animals
This test is mainly based on scents from the juvenile. Attempts were made to refine the test to reduce the number of animals ... introduction and use of alternatives to laboratory animals in biomedical research and testing. ... This test measures social memory by using, in general, juvenile rats as stimulus animals. Rats are offered a first juvenile to ... Is it Possible to Replace Stimulus Animals by Scent-filled Cups in the Social Discrimination Test?. Ruud van den Bos, Klaske J ...
http://www.atla.org.uk/tag/social-discrimination-test/
*  Lipton - Wikipedia
"Developing alternative approaches to animal testing". Unilever. Retrieved 8 June 2016. "Search results for 'soup'". Lipton Tea ... Zelman, Joanna (2 February 2011). "Unilever Ends Animal Testing On Lipton Tea Products After PETA Threatens Major Campaign". ... campaign Unilever no longer test their products on animals unless required to by governments as part of their regulatory ... According to the animal rights organization, Unilever decided to end the practice for Lipton products after receiving more than ...
https://en.wikipedia.org/wiki/Lipton
*  Combating heart disease with lab-grown "hearts-in-a-jar"
Despite the use of innumerable animals in cardiac experiments, cardiotoxicity - damage to the heart - remains the key reason ... Alternatives to Animal Testing, Experimentation and Dissection - An Animal Rights Article from All-Creatures.org. ... FROM CAARE Citizens for Alternatives to Animal Research and Experimentation. January 2019. Despite the use of innumerable ... In contrast, Novoheart's organoid mini-hearts open up a whole host of possibilities impossible with animal tests. Their ...
https://www.all-creatures.org/articles/ar-alt-lab-grown-hearts.html
*  IIVS Releases Training Video to Replace Animals in Testing
Funded by a grant from the European Partnership for Alternative Approaches to Animal Testing (EPAA), the Institute for In ... Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS , IIVS Releases Training Video to Replace Animals in ... The European Partnership for Alternative Approaches to Animal Testing (EPAA) is a partnership between industry and the European ... EPAA, the European partnership for Alternative Approaches to animal testing between the European Commission and Industry, has ...
https://iivs.org/2016/11/19/iivs-releases-training-video-to-replace-animals-in-testing/
*  Leslie Turnberg, Baron Turnberg - Wikipedia
"The Three Rs: The Way Forward". The Center for Alternatives to Animal Testing. Archived from the original on 28 March 2007. ... in animal testing called "The National Centre for the Replacement, Refinement and Reduction of Animals in Research". The board ... The focus of the centre is on the three Rs: the replacement, refinement, and reduction of animal testing. The three Rs were ... The UK government currently still regards animal testing as necessary, but science minister Lord Sainsbury of Turville said ...
https://en.wikipedia.org/wiki/Leslie_Turnberg,_Baron_Turnberg
*  Project management: importance for diagnostic laboratories.
Animal Testing Alternatives. Procedures, such as TISSUE CULTURE TECHNIQUES; mathematical models; etc., when used or advocated ... Laboratory Proficiency Testing. Assessments aimed at determining agreement in diagnostic test results among laboratories. ... Rabies continues to pose a significant threat to human and animal health in regions of Indonesia. Indonesia has an extensive ... The objective of this project is to develop a non-invasive prenatal diagnostic test for trisomy 21 which is reliable, sensitive ...
https://www.bioportfolio.com/resources/pmarticle/1725104/Project-management-importance-for-diagnostic-laboratories.html
*  Pyrogen - definition of pyrogen by The Free Dictionary
n any of a group of substances that cause a rise in temperature in an animal body n. a substance, as a bacterial toxin,... ... RESEARCH: NEW ALTERNATIVES TO ANIMAL TESTING UNVEILED. Tenders invited for Supply of 16 x 100 mm pyrogen free glass tubes, 10 x ... regulatory agencies for the test's broader use in lot-release pyrogen testing.. Charles River Introduces 'In Vitro' Test ... The global pyrogen testing market is projected to reach USD 1086.. Pyrogen Testing Market Rising at 12.2% CAGR to Hit $1086.3MM ...
https://www.thefreedictionary.com/pyrogen
*  Social Media Channels - News - Johns Hopkins Bloomberg School of Public Health
Center for Alternatives to Animal Testing. RSS Feeds. RSS (Really Simple Syndication) is a family of Web feed formats used to ...
https://www.jhsph.edu/news/social-media-channels/index.html
*  ECEAE | The Truth About Botox Animal Testing
If we don't test on animals how can we ensure botox is safe?. A number of alternatives to the LD50 test for botox have been ... How many animals are used to test botox?. It is estimated that 300,000 mice are used worldwide to test botox each year. The ... What animal test is carried out for botox?. Because the toxin is potentially highly dangerous, each batch is tested before it ... Why aren't the manufacturers using alternatives to animal tests?. The other manufacturers of botox botulinum toxin products ...
http://www.eceae.org/hr/what-we-do/campaigns/botox/the-truth-about-botox-animal-testing
*  New approaches needed to assess the effects of inhaled substances on human health - European Commission
... a focus on non-animal testing approaches.Scientists from the JRC's EU Reference Laboratory for Alternatives to Animal Testing ( ... They discussed how existing knowledge can be used to design effective non-animal testing approaches. ... Scientists from the JRC's EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) joined a working group, ... Designing and testing integrated approaches. These mechanistic based non-animal approaches will provide a predictive tool and ...
https://ec.europa.eu/jrc/en/science-update/new-approaches-assess-effects-inhaled-substances-human-health
*  Expert workshop to capture inflammatory processes within the Adverse Outcome Pathway framework - European Commission
This will contribute to the ongoing work to accelerate progress in the development of non-animal test methods. ... AOPs that share one or more events form networks and facilitate the prediction of adversities based on non-animal test methods. ... This will contribute to the ongoing work to accelerate progress in the development of non-animal test methods. ...
https://ec.europa.eu/jrc/en/science-update/inflammatory-processes-within-adverse-outcome-pathway-framework
*  Strategies to improve the regulatory assessment of Developmental Neurotoxicity (DNT) using in vitro methods - European...
DNT testing is only performed in higher tiered testing triggered based on chemical structure activity relationships or evidence ... Therefore, there is a pressing need for developing alternative methodologies that can reliably support identification of DNT ... Since at the regulatory level, systematic testing of DNT is not a standard requirement within the EU or USA chemical ... A battery of DNT in vitro test methods derived from hiPSCs could generate valuable mechanistic data, speeding up the evaluation ...
https://ec.europa.eu/jrc/en/publication/strategies-improve-regulatory-assessment-developmental-neurotoxicity-dnt-using-vitro-methods
*  Queen Mary University of London - Wikipedia
"Professorial chair to lead search for animal testing alternatives". Times Higher Education. 16 January 2013. Retrieved 20 ... In January 2013, Queen Mary established the world's first professorial chair in animal replacement science. From 2014, Queen ...
https://en.wikipedia.org/wiki/Queen_Mary_University_of_London
*  History of Queen Mary University of London - Wikipedia
"Professorial chair to lead search for animal testing alternatives". Times Higher Education. 16 January 2013. Retrieved 20 ... "Thurston's DH4 Tests". Retrieved 11 September 2011. "Spratt's". London Remembers. Retrieved 16 July 2015. "Information released ... In January 2013, Queen Mary established the world's first professorial chair in animal replacement science. From 2014, Queen ...
https://en.wikipedia.org/wiki/History_of_Queen_Mary_University_of_London