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*  Alternatives to animal testing | News | CORDIS | European Commission
Background Animals are still used abundantly to assess the efficacy and safety of cosmetics, medicines, food additives,...,FP4- ... Human health and animal welfare both stand to gain from the development of new in vitro toxicology tests, based on cultured ... or refine animal testing. Directive 86/609/EEC bans the use of an animal test when an equally satisfactory alternative test is ... Alternatives to animal testing. Human health and animal welfare both stand to gain from the development of new in vitro ...
https://cordis.europa.eu/news/rcn/14402_en.html
*  CORDIS Archive : CORDIS: Quality of Life: Documents: Newsletter NÂș8 - July 2002
Project synopses "Research on alternatives to animal experimentation and testing in the QoL programme" July 2002 Contact: ( ... Reduction and Refinement alternatives to animal experimentation and testing" Contact: (email removed) ...
http://cordis.europa.eu/life/src/news0800.htm
*  OpenRiskNet: Open e-Infrastructure to Support Data Sharing, Knowledge Integration and in silico Analysis and Modelling in Risk...
... a mechanistic discipline based on in vitro and in silico approaches that represent an important alternative to classical animal ... testing applied to the evaluation of chronic and systemic...,EINFRA-22-2016,JOHANNES GUTENBERG-UNIVERSITAT MAINZ(DE),STICHTING ... discipline based on in vitro and in silico approaches that represent an important alternative to classical animal testing ...
https://cordis.europa.eu/project/rcn/206759_es.html
*  Commission proposes banning animal testing for cosmetics in the EU | News | CORDIS | European Commission
The amendment involves changing the marketing ban of products containing ingredients tested on animals after 1 July 2000 i..., ... adopted a proposal for a directive which would amend current legislation in the Member States on testing cosmetics on animals. ... A way out of this dilemma is the development of 'validated alternative methods to animal testing' which is promoted by the ... The issue of animal testing for cosmetic purposes is of key importance. On the one hand, animal testing of cosmetics is ...
https://cordis.europa.eu/news/rcn/14681_en.html
*  Development of Gene Therapy Strategies for Neurological Diseases | Projects | FP4-BIOMED 2 | CORDIS | European Commission
Alternative gene constructs where the transgene is under the control of endogenous, cell-specific promoters containing suitable ... This will allow function of the transduced cells to be evaluated over longer time periods and in complex functional tests .. ... The various methods developed within the programme will be validated in small animal models and a primate model of PD. ... Encapsulation techniques for the transplantation of genetically engineered allo and xenogeneic cell lines will be tested.. The ...
https://cordis.europa.eu/project/rcn/32502_pl.html
*  Final Report Summary - GMSAFOOD (Biomarkers for post market monitoring of short and long-term effects of genetically modified...
While there are numerous in vitro tests for allergenicity of proteins and animal models and animals (livestock) to test for ... They are a valuable, alternative protein/nutrient source suitable for feeding monogastric animals and for human consumption. ... in addition to skin-prick testing. Protein stability in pepsin is also tested as a predictor. These are considered useful tests ... 4. Establish Biomarkers for GMO-induced immunogenicity and allergenicity in animals and humans 5. To test Bt-maize as an ...
https://cordis.europa.eu/result/rcn/56044_pl.html
*  Final Report Summary - HIVINNOV (Generation of a new class of antiretrovirals targeting HIV-cellular cofactors interactions) |...
The results of these tests were very encouraging for the future development of BDM2 since these tests fully confirm the high ... An alternative solution was looked for with a second CRO selected on the basis of its ability to achieve the scaling up of this ... In the absence of clinical phase IIa POC trial, this result in an animal model of HIV infection in humanized mice is a major ... activity well conserved against all polymorphic viruses tested and against all primary isolates from different clades tested. ...
https://cordis.europa.eu/result/rcn/184165_en.html
*  Final Report Summary - EUTRAF (The European Network for Translational Research in Atrial Fibrillation) | Report Summary |...
We will also test the relevance of PITX2 dependent genes in the response of the atria and the heart to injury and chronic ... Short-term AF has been reported to induce a profound reduction in atrial nitric oxide (NO) release in animal models and ... but few proven alternative strategies exist for when it fails, particularly for persistent AF. To help develop and guide novel ... We tested this hypothesis in an in vivo study using the recently approved dual ET receptor antagonist, Macitentan.. In the DOCA ...
https://cordis.europa.eu/result/rcn/183644_es.html
*  Final Report Summary - BASEFOOD (Sustainable exploitation of bioactive components from the Black Sea Area traditional foods) |...
On the basis of the previous observations, two alternative flowcharts were implemented and tested, in comparison with the ... Potential of plant extracts to modulate host immune defense and regulate the key representatives of gut microbiota in animal ... This part of the work was devoted: a) at testing the effect of plant extracts on the equilibrium of gut microbiota in mice, by ... In a second stage the dose-response effect of extracts that revealed some effect were tested. All the plants or food extracts ...
https://cordis.europa.eu/result/rcn/143081_en.html
*  Final Report Summary - FORESTSPECS (Wood Bark and Peat Based Bioactive Compounds, Speciality Chemicals, and Remediation...
... and cream-gel with betulin were evaluated for irritation and allergic effects using guinea pigs as test animals. The irritant ... 3.4.3. Large scale production of bark based composts as an alternative to peat-based substrates in horticulture. Forest soils ... The tested compounds were betulonic acid and abietic acid. The aim was to test if the selected compounds deter egg laying and/ ... 3.3.3. Tests for herbicidal activity. Total of 95 extracts/compounds which were produced in ForestSpeCs were tested for their ...
https://cordis.europa.eu/result/rcn/149969_en.html
*  Final Report Summary - GENCOMMONS (Institutionalizing global genetic-resource commons. Global Strategies for accessing and...
... exchange networks shows that networking pools of genetic resources in local and global commons provides a workable alternative ... Research on microbial, plant and animal genetic resource exchange networks shows that networking pools of genetic resources in ... to fully implement and test the proposed economic and legal solutions for fully institutionalizing the genetic resource commons ... local and global commons provides a workable alternative to market-based solutions, which have shown to be unable to generate ...
https://cordis.europa.eu/result/rcn/197305_en.html
*  Periodic Reporting for period 1 - VIRIDIS MIST (A toxin-free, food-safe, autonomous mobile misting disinfection system that...
We have also confirmed the interest of early adopters to perform end user testing during the Phase2 project. In planning the ... therefore we consider that the threat of competing viable alternatives also reaching the market does not constitute a major ... assist in reducing the level of toxins from entering the food chain and water sources as well as make improvements in animal ... Our formulation has been tested through a localised application, however it has neither been proven or validated to work with a ...
https://cordis.europa.eu/result/rcn/238873_en.html