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*  The Principles of Humane Experimental Technique: Preface
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... Since many animals are used for repeated experimentation, the Home Office figures must overestimate the number of animals used ... It contains a wealth of information on animal utilization as well as animal procurement; the latter subject, however, was the ... THE ECOLOGY OF EXPERIMENTAL ANIMALS. We may infer that our domestic animals were originally chosen... because they were useful ...
http://altweb.jhsph.edu/pubs/books/humane_exp/chap3b
*  Scottish Scientists Developing In Vitro Artificial Liver
... a technology they say has the potential to both speed up and slash the cost of testing and producing new drugs. ... the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... If we could establish better in-vitro models than animals using artificial human tissues or organs, the animal testing may ... "On top of this, it is often argued that animal models are not ideal when testing drugs destined for use in humans. ...
http://altweb.jhsph.edu/news/2012/scottish_artificial_liver.html
*  The Principles of Humane Experimental Technique: Preface
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... Friedman test), toad (toad test), Xenopus (Hogben test), and a few rats. General Diagnosis is almost entirely the preserve of ... It was not possible from the returns to separate "toxicity testing" into screening and batch testing. I may add a brief note on ... THE ECOLOGY OF EXPERIMENTAL ANIMALS. We may infer that our domestic animals were originally chosen... because they were useful ...
http://altweb.jhsph.edu/pubs/books/humane_exp/chap3e
*  The Principles of Humane Experimental Technique: Preface
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... In this sense, there can be no doubt that for lower animals (the source for much of our knowledge of all the physiological ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ... The vertical dashed line divides, roughly, the outside of the animal (milieu extérieur) from the inside (milieu intérieur). The ...
http://altweb.jhsph.edu/pubs/books/humane_exp/chap1b
*  AlTEX 32.1
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... Integrated testing strategies (ITS) for safety assessment. Pete Otovic and Eric Hutchinson Limits to using HPA axis activity as ... Safety testing of veterinary vaccines using magnetic resonance imaging in pigs. SHORT COMMUNICATION. Maria C. C. M. Inglez de ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ...
http://altweb.jhsph.edu/altex/32_1/index.html
*  The Principles of Humane Experimental Technique: Preface
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... It is therefore worth examining this test.. "Several animals should be inoculated since some are likely to die of peritonitis ... Contrary to the fatalistic advice of the textbook just cited (and apparently without detriment), one animal was used per test. ... But as long as any animals are used for this purpose, we may hope to see in vitro methods promoted (King and Frobisher, 1949). ...
http://altweb.jhsph.edu/pubs/books/humane_exp/chap4c
*  8th World Congress on Alternatives and Animal Use in the Life Sciences
... spanning from toxicity testing to animal welfare policy to issues unique to farm animal and wildlife research, and is divided ... Theme I: Safety and efficacy testing of chemicals, pharmaceuticals and biological. Theme II: Policy/law on animal use, public ... The World Congresses on Alternatives and Animal Use in the Life Sciences are the longest running series of international ... of animal use in research and safety testing. Since 1993, these conferences have been held every 2-3 years, and have attracted ...
http://altweb.jhsph.edu/news/current/8worldcongress.html
*  Altex: 3/09 Index
The Center for Alternatives to Animal Testing-Europe (CAAT-EU): a transatlantic bridge for the paradigm shift in toxicology. ... Food for thought … on alternative methods for chemical safety testing. t4 REVIEW. Philipp B. Kuegler, Bastian Zimmer, Tanja ... First alternative method validated by a retrospective weight-of-evidence approach to replace the Draize eye test for the ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ...
http://altweb.jhsph.edu/altex/27_1/index.html
*  Altweb: ALTEX: 2/09: Food for thought ... on evidence-based toxicology
Center for Alternatives to Animal Testing. 615 N. Wolfe St.. E7035. Baltimore, MD, 21205. USA. e-mail: thartung@jhsph.edu ... My key desire to evaluate current test methods (especially animal test methods) in the most objective way to open up the field ... Center for Alternatives to Animal Testing, Baltimore, USA ... Hartung, T. (2008b). Food for thought … on animal tests. ALTEX ... Hartung, T. and leist, M. (2008). Food for thought … on the evolution of toxicology and phasing out of animal testing. ALTEX 25 ...
http://altweb.jhsph.edu/altex/26_2/foodforthought.html
*  About Us - Altweb: Alternatives to Animal Testing - Johns Hopkins Bloomberg School of Public Health
Altweb, the Alternatives to Animal Testing Web Site, was created to serve as a gateway to alternatives news, information, and ... which is the official publication of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT). ... Altweb now is the U.S. home of the journal ALTEX: Alternatives to Animal Experimentation, ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ...
http://altweb.jhsph.edu/about_us/
*  Altweb: ALTEX: 2/09: CAATfeed
The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) has worked with scientists since 1981 to find new methods to ... replace the use of laboratory animals in experiments, reduce the number of animals tested, and refine necessary tests to ... ALTEX: Alternatives to Animal Experimentation is now the official journal of CAAT and the Transatlantic Think Tank of ... seed money for scientists to develop alternatives to the use of animals in biomedical research and product safety testing. To ...
http://altweb.jhsph.edu/altex/26_2/caatfeed.html
*  The Principles of Humane Experimental Technique: Preface
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... In several cases, what there was of it did not differ significantly between test and unused animals, and can, therefore, be ... Out of 840 inoculated, 21 died (cause unspecified). In the same year, out of a smaller number, 57 stock animal died.. Out of ... Deaths in P.D. tests due to toxic urines can, however, be largely eliminated by suitable chemical treatment of the urine, such ...
http://altweb.jhsph.edu/pubs/books/humane_exp/chap4a
*  ALTEX 30.4
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ... A roadmap for hazard monitoring and risk assessment of marine biotoxins on the basis of chemical and biological test systems ... Building a Better Epithelium: Breaking the Barrier to the Next Generation of Toxicity Testing. March 10, 2018. San Antonio, TX ...
http://altweb.jhsph.edu/altex/30_4/
*  The Principles of Humane Experimental Technique: Preface
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... Now can a lower animal obtain the precious relief of verbalizing its distress. Far from despising lower animals (as it is ... In this respect, animals are functionally similar to neurotic humans, and, since we are all neurotic to some extent, most of us ... The lower animal, is therefore, specially vulnerable to unpleasant conditions. When it is in a distressful mood, this is very ...
http://altweb.jhsph.edu/pubs/books/humane_exp/chap2a
*  Altweb: Acronyms
EPAA (European Partnership for Alternative Approaches to Animal Testing). *EURCA (European Resource Centre for Alternatives in ... FRANCOPA (French Platform for the Development of Alternative Methods in Animal Testing) ... University of California Center for Animal Alternatives) [USA]. *ZEBET (Centre for Documentation and Evaluation of Alternative ... Netherlands Knowledge Centre on Alternatives to Animal Use, Formerly NCA). *Norwegian Reference Centre for Laboratory Animal ...
http://altweb.jhsph.edu/3rscenters.html
*  ATLA Issue 40.6 Now Available
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ... Building a Better Epithelium: Breaking the Barrier to the Next Generation of Toxicity Testing. March 10, 2018. San Antonio, TX ... "Training needs for toxicity testing in the 21st century: a survey-informed analysis," FRAME's annual lecture, and much more. ...
http://altweb.jhsph.edu/news/2012/new_ATLA_40_6.html
*  Altweb: Search for Alternatives: Databases
Invitroderm - Alternatives to skin irritation and corrosion testing in animals, searchable bibliography with abstracts. ... ZEBET is responsible for documentation and information on alternatives to animals in research and testing. The ZEBET database ... NORINA - Norwegian Inventory of Alternatives, Norwegian Reference Centre for Laboratory Animal Science and Alternatives. ... testing, application, and validation of alternatives to the use of vertebrates in biomedical research and toxicology testing. ...
http://altweb.jhsph.edu/resources/searchalt/searchaltdata.html
*  University of Konstanz and Johns Hopkins Bloomberg School of Public Health Establish Center of Alternatives to Animal Testing...
... in an effort to promote better coordination in toxicity testing. ... Health have jointly established the Center for Alternatives to ... Center for Alternatives to Animal Testing-Europe. Universitaetsstraße 10, 78464 Konstanz. Tel.: +49 (0)7531-884685. Email. Tim ... University of Konstanz and Johns Hopkins Bloomberg School of Public Health Establish Center of Alternatives to Animal Testing- ... The new Center, modeled after the Bloomberg School's Center for Alternatives to Animal Testing (CAAT), will conduct scientific ...
http://altweb.jhsph.edu/news/2010/caateupressrelease.html
*  CAAT-Europe Information Day: REACH, TSCA Reauthorization, and Toxicology of 21st Century
... and the implementation of the US National Research Council strategy for Toxicity Testing in the 21st Century. ... The Center for Alternatives to Animal Testing in Europe (CAAT-EU) operates as a joint venture of the University of Konstanz, ... Toxicity Testing in the 21st Century which put forward the vision on advanced toxicity testing and human health assessment. The ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ...
http://altweb.jhsph.edu/news/2010/caateuinfoday.html
*  The Principles of Humane Experimental Technique: Preface
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... The first and second of these tests do not wholly eliminate toxic effects, but the Hogben test has been refined by suitable ... can now be produced in large animals, such as sheep; this procedure naturally also requires fewer animals (Stratton, 1956).. ... The toad test is, still, less accurate than the two best, but ease of provenance may have resulted in an increase in its use.2 ...
http://altweb.jhsph.edu/pubs/books/humane_exp/chap4b
*  Guide for the Care and Use of Laboratory Animals: Eighth Edition
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal ... It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and ... and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides ...
http://altweb.jhsph.edu/pubs/books/Guide%20for%20the%20Care%20and%20Use%20of%20Laboratory%20Animals/
*  The Principles of Humane Experimental Technique: Preface
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ... Few people have been more concerned than he was with the welfare of experimental animals, or more active in furthering the ... We have also received valuable assistance from the Animal Welfare Institute of the U.S.A., which also contributed financially ...
http://altweb.jhsph.edu/pubs/books/humane_exp/preface
*  ALTEX Issue 31.1
... an article about an alternative QSAR-based approach for predicting the bioconcentration factor for regulatory purposes, and ... the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ... Building a Better Epithelium: Breaking the Barrier to the Next Generation of Toxicity Testing. March 10, 2018. San Antonio, TX ...
http://altweb.jhsph.edu/altex/31_1/index.html
*  The Principles of Humane Experimental Technique: Preface
the global clearinghouse for information on alternatives to animal testing. Search Altweb. ... Tables 6, 10, and 18). This assay is concentrated in a very few laboratories, and may be regarded as a test case. It is far ... 2nd Pan-American Conference for Alternative Methods. August 23-24, 2018. Rio de Janeiro, Brazil Eurotox 2018. September 2-5, ... The chief of these conditions is the case where very large numbers of animals are employed daily in a single laboratory ( ...
http://altweb.jhsph.edu/pubs/books/humane_exp/chap4e
*  Altweb: ALTEX: Alternatives to Animal Experiments
... the Johns Hopkins Center for Alternatives to Animal Testing), EUSAAT (the European Society for Alternatives to Animal Testing ... Animal experiments are defined by the editors as all experimental procedures involving the use of animals in testing, research ... ALTEX is devoted to the publication of research on the development and promotion of alternatives to animal experiments ... and education, or to obtain tissues, organs, and other animal derived products that may cause pain or distress to animals. ...
http://altweb.jhsph.edu/altex