Although aldosterone antagonists are available for the treatment of hypertension with cardiac hypertrophy, concern remains ... Furthermore, FGF23 not only inhibits the renal expression of angiotensin converting enzyme 2 but also enhances renin gene ... types of calcium channel blockers suppress aldosterone synthesis or exert blocking action for mineralocorticoid receptors and ... transcription, both of which could accelerate renin-angiotensin-aldosterone system. Although the increase in serum phosphate ...