Amyloid Precursor Protein SecretasesAmyloid beta-Protein PrecursorAspartic Acid EndopeptidasesAmyloid beta-PeptidesAlzheimer DiseaseAmyloidEndopeptidasesPresenilin-1Plaque, AmyloidProtein PrecursorsMice, TransgenicProtease NexinsSerum Amyloid A ProteinPeptide FragmentsBrainPresenilin-2NeuronsProtein Processing, Post-TranslationalAmyloidosisCerebral Amyloid AngiopathyPresenilinsMolecular Sequence DataAmino Acid Sequencetau ProteinsProtein Structure, TertiaryMembrane ProteinsNerve Tissue ProteinsAmyloidogenic ProteinsMutationDisease Models, AnimalAmyloid NeuropathiesHippocampusCell LineCells, CulturedIslet Amyloid PolypeptideCerebral CortexLDL-Receptor Related ProteinsProtein TransportProtein BindingMice, Inbred C57BLTransfectionMaze LearningProteolysisImmunohistochemistryCHO CellsBlotting, WesternCricetinaeNeurofibrillary TanglesAxonal TransportBase SequencePC12 CellsADAM ProteinsNerve DegenerationGene Expression RegulationMice, KnockoutConvolvulusRecombinant ProteinsSerum Amyloid P-ComponentPrionsNeuroblastomaInsulysinProtease InhibitorsReceptors, NotchNeuritesEnzyme-Linked Immunosorbent AssayBrain ChemistryRNA, MessengerAgingCongo RedCell MembraneCricetulusAxonsNeprilysinEndosomesMemory DisordersRecombinant Fusion ProteinsCell Line, TumorGliosisModels, BiologicalImmunoprecipitationMicrogliaBinding SitesPeptidesCOS CellsHEK293 CellsDipeptidesClioquinolAstrocytesGene ExpressionSignal TransductionAlzheimer VaccinesApolipoproteins EHistory, Early Modern 1451-1600KineticsEnzyme PrecursorsNeurodegenerative DiseasesBiotinylationSynaptophysinTime FactorsPrealbumin