... ethylmorphine N-demethylase activity was affected the most whereas aminopyrine N-demethylase and hexobarbital oxidase ... Furthermore, these differences in responsiveness seem to be a delayed event, since hepatic aminopyrine N-demethylase activity ... The effect of neonatal androgen on the apparent Michaelis constant (Km) of ethylmorphine N-demethylase was also studied in the ... respond less to androgen treatment at adulthood for the metabolism of aminopyrine, ethylmorphine and hexobarbital as compared ...
1 synonym for amidopyrine: aminopyrine. What are synonyms for amidopyrine? ... 450s] (except hepatic amidopyrine N-demethylase and aniline 4-hydroxylase activities).. A significant inhibition of hepatic ... aminopyrine,type:2},{name:analgesic,type:4},{name:anodyne,type:4},{name:pain pill,type:4},{name: ... amidopyrine N-demethylase in liver microsomes was expressed as [micro]mol/min x kg liver sample, aniline-4-hydroxylase was ...
In contrast to the biphasic kinetic behavior of hepatic aminopyrine N-demethylase, brain aminopyrine N-demethylation exhibited ... In contrast to the biphasic kinetic behavior of hepatic aminopyrine N-demethylase, brain aminopyrine N-demethylation exhibited ... In contrast to the biphasic kinetic behavior of hepatic aminopyrine N-demethylase, brain aminopyrine N-demethylation exhibited ... In contrast to the biphasic kinetic behavior of hepatic aminopyrine N-demethylase, brain aminopyrine N-demethylation exhibited ...
Liver aminopyrine N-demethylase activity was increased in all permethrin-treated animals. Bone marrow smears of the animals ... Hepatic aminopyrine N-demethylase activity was also substan- tially increased, although not consistently, in both male and ... increased liver aminopyrine- N-demethylase ac- tivity, increased liver weight, and eosinophilia of hepatocytes in both males ... increased liver aminopyrine- N-demethylase activity in both males and females at 1000 and 2500 mg/kg, and hepatocyte ...
DEVELOPMENT OF HEPATIC N-DEMETHYLASE ACTIVITY AS MEASURED IN VIVO BY THE AMINOPYRINE BREATH TEST *Robert J Shulman ... Rights & permissionsfor article DEVELOPMENT OF HEPATIC N-DEMETHYLASE ACTIVITY AS MEASURED IN VIVO BY THE AMINOPYRINE BREATH ... Rights & permissionsfor article Effect of Infant Age on Aminopyrine Breath Test Results . Opens in a new window. ... Effect of Infant Age on Aminopyrine Breath Test Results *Robert J Shulman ...
The effects on aminopyrine-demethylase and acetanilide-hydroxylase activity were evaluated. The extracts were examined by thin ... Isooctane did not inhibit aminopyrine-demethylase or acetanilide-hydroxylase activity. TLC spots corresponding to ...
The activity of aminopyrine demethylase rose by a factor of 2.2 and the mean liver weights increased by 35%. There was a ... aminopyrine demethylase activities, for levels of cytochromes P-450 and b5, and for microsomal protein concentration. At 27,000 ...
Aminopyrine N-demethylase (APDM) activity and electron microscopy on liver samples (6 males and 6 females/group). Statistics:. ... A statistically significant increase in liver aminopyrine N-demethylase activity was seen in animals of both sexes given the ... A statistically significant increase in liver aminopyrine N-demethylase activity was seen in animals of both sexes given the ... Aminopyrine N-demethylase and electron microscopy).. Executive summary:. Sprague Dawley CD rats of received diets containing ...
The effects on aniline-p-hydroxylase, acetanilide-hydroxylase, and aminopyrine-N- demethylase activity were investigated. IPI ... hydroxylase and acetanilide-hydroxylase and noncompetitively inhibited aminopyrine-N-demethylase, IPI being the more potent. ...
Pretreatment with momordin Ic and oleanolic acid resulted in significantly lower production of aminopyrine N-demethylase and ... Pretreatment with momordin Ic resulted in lower catalase and aminopyrine N-demethylase activity induction by CCl4, towards ...
Nickel carbonyl inhibition of induction of aminopyrine demethylase activity in liver and lung. Cancer Res 1970;30:1645-50. ... Noda A, Tsubone N, Mihara M, Goromaru T, Iguchi S. Formation of 4-formylaminoantipyrine as a new metabolite of aminopyrine. II ... Mirvish SS, Gold B, Eagen M, Arnold S. Kinetics of the nitrosation of aminopyrine to give dimethylnitrosamine. Clin Oncol 1974; ... Bast A, Noordhoek J. Inhibition of aminopyrine demethylation and binding to cytochrome P-450 by its main metabolites in rat ...
Competitive inhibition was followed by Lineweaver-Burke analyses of aminopyrine demethylase in operated females treated with ... aminopyrine demethylase and aromatic hydrocarbon or benzo[a]pyrene hydroxylase). Groups were also induced with phenobarbital ... P-450 and the other steroids screened had little effect on the microsomal parameters except for a rise in demethylase with ...
Critical role of lipid peroxidation in carbon tetrachloride-induced loss of aminopyrine demethylase, cytochrome P-450 and ...
Characterization of cytochrome P-450-dependent aminopyrine N-demethylase in rat brain: comparison with hepatic aminopyrine N- ...
CHLORINATED PARAFFINS 463 females; females: increased aminopyrine N-demethylase activity, N- acetylglucosaminidase activity, ... CHLORINATED PARAFFINS 446 pyrine N-demethylase activities were increased in male and female Sprague-Dawley rats fed 5,000 ppm ...
There was no statistical difference between C/C, C/T, and T/T dogs in activities of aminopyrine N-demethylase, aniline ... Caffeine 7-Demethylase, 3-Demethylase, 1-Demethylase, and 8-Hydroxylase Assay. Caffeine (1 mM) was incubated for 30 min at 37°C ... Activities of caffeine 7-demethylase (13X), caffeine 3-demethylase (17X), caffeine 1-demethylase (37X), and caffeine 8- ... caffeine 7-demethylase; 17X, caffeine 3-demethylase; 37X, caffeine 1-demethylase; 137U, caffeine 8-hydroxylase; MLT, melatonin ...
Results: The activities of benzphetamine and aminopyrine Ar-demethylase were increased in the cultural fetal adrenal cells ... The activities of 7-ethoxyresorufin 0-dealkylase, benzphetamine, aminopyrine and erythromycin N-demethylases were measured by ... Aryl hydrocarbon hydroxylase (AHH) and dimethylnitrosamine demethylase (DMND) activities in pulmonary and hepatic tissues of ... also increased the activity of erythromycin W-demethylase. The activity of 7-ethoxyresorufin 0-dealkylase was undetected in the ...
Benzofuran administration also caused decreases in cytochrome P-450 levels and aminopyrine N-demethylase activities. ...
3) The activity of aminopyrine demethylase, the contents of cytochrome P-450 and b5, and the spectral difference of aniline ...
... including cytochrome P-450 and aminopyrine- N- demethylase; cytochrome- c-reductase activity was decreased, and those of ... demethylase, and cytochrome- c-reductase. The activities of the phase-II drug metabolizing enzymes glucuronyl transferase I and ... demethylase, benzo[ a]pyrene hydroxylase, 7-ethoxycoumarin-deethylase, and cytosolic glutathione- S-transferase were measured. ...
... aminopyrine n-demethylase MeSH D08.811.682.662.582.338 --- cytochrome p-450 cyp2e1 MeSH D08.811.682.662.582.353 --- cytochrome ... nitroanisole o-demethylase MeSH D08.811.682.690.416 --- dioxygenases MeSH D08.811.682.690.416.277 --- catechol 1,2-dioxygenase ... ethylmorphine-n-demethylase MeSH D08.811.682.662.582.550 --- sarcosine dehydrogenase MeSH D08.811.682.662.582.700 --- sarcosine ...
Renton KW, Aranda JV, and Eade NR (1976) NADPH-dependent lipid peroxidation and its effects on aminopyrine N-demethylation in ... THE EFFECT OF CIMETIDINE ON DEXTROMETHORPHAN O-DEMETHYLASE ACTIVITY OF HUMAN LIVER MICROSOMES AND RECOMBINANT CYP2D6. Maria ... THE EFFECT OF CIMETIDINE ON DEXTROMETHORPHAN O-DEMETHYLASE ACTIVITY OF HUMAN LIVER MICROSOMES AND RECOMBINANT CYP2D6. Maria ... THE EFFECT OF CIMETIDINE ON DEXTROMETHORPHAN O-DEMETHYLASE ACTIVITY OF HUMAN LIVER MICROSOMES AND RECOMBINANT CYP2D6. Maria ...
... aminopyrine-N-demethylase, erythromycin N-demethylase, aniline 4-hydroxylase and NADPH-cytochrome C reductase) and down- ...
... aminopyrine N-demethylase, and cytochrome c reductase were not significantly altered by dietary selenium levels. Concurrent ...