Loading...
*  TIGR00399
The methionyl-tRNA synthetase (metG) is a class I amino acyl-tRNA ligase. This HMM describes a region of the methionyl-tRNA ... Proteins hit by this HMM should called methionyl-tRNA synthetase beta chain if and only if the HMM metG hits a separate protein ... synthetase that is present at the C-terminus of MetG in some species (E. coli, B. subtilis, Thermotoga maritima, ...
http://www.jcvi.org/cgi-bin/tigrfams/HmmReportPage.cgi?acc=TIGR00399
*  pars-2 - Prolyl Amino-acyl tRNA Synthetase - Caenorhabditis elegans - pars-2 gene & protein
Prolyl Amino-acyl tRNA SynthetaseImported. ,p>Information which has been imported from another database using automatic ... tr,O45869,O45869_CAEEL Prolyl Amino-acyl tRNA Synthetase OS=Caenorhabditis elegans GN=pars-2 PE=1 SV=1 ... Aminoacyl-tRNA synthetaseImported. ,p>Information which has been imported from another database using automatic procedures.,/p ... IPR002314. aa-tRNA-synt_IIb. IPR006195. aa-tRNA-synth_II. IPR004154. Anticodon-bd. IPR036621. Anticodon-bd_dom_sf. IPR002316. ...
http://www.uniprot.org/uniprot/O45869
*  cars-1 - Cysteinyl Amino-acyl tRNA Synthetase - Caenorhabditis elegans - cars-1 gene & protein
Cysteinyl Amino-acyl tRNA SynthetaseImported. ,p>Information which has been imported from another database using automatic ... tr,A0A061ACL3,A0A061ACL3_CAEEL Cysteinyl Amino-acyl tRNA Synthetase OS=Caenorhabditis elegans OX=6239 GN=cars-1 PE=1 SV=1 ... Aminoacyl-tRNA synthetaseImported. ,p>Information which has been imported from another database using automatic procedures.,/p ... IPR015803 Cys-tRNA-ligase. IPR024909 Cys-tRNA/MSH_ligase. IPR032678 tRNA-synt_1_cat_dom. IPR009080 tRNAsynth_Ia_anticodon-bd. ...
https://www.uniprot.org/uniprot/A0A061ACL3
*  Aminoacyl tRNA synthetase - Wikipedia
Amino+Acyl-tRNA+Synthetases at the US National Library of Medicine Medical Subject Headings (MeSH) ... "Aminoacyl-tRNA synthetases". Structural Biology. 5: 48-55.. *^ "Molecule of the Month: Aminoacyl-tRNA Synthetases High Fidelity ... An aminoacyl-tRNA synthetase (aaRS or ARS), also called tRNA-ligase, is an enzyme that attaches the appropriate amino acid onto ... Amino Acid + tRNA + ATP → Aminoacyl-tRNA + AMP + PPi. Some synthetases also mediate an editing reaction to ensure high fidelity ...
https://en.wikipedia.org/wiki/Aminoacyl_tRNA_synthetase
*  Mitochondrial aminoacyl-tRNA synthetases in human disease. - PubMed - NCBI
Amino Acyl-tRNA Synthetases/genetics*. *Amino Acyl-tRNA Synthetases/metabolism. *Brain Diseases, Metabolic/enzymology ... Mitochondrial aminoacyl-tRNA synthetases in human disease.. Konovalova S1, Tyynismaa H. ... Mitochondrial aminoacyl-tRNA synthetases (mtARSs) are essential in the process of transferring genetic information from ... These synthetases perform an integral step in the initiation of mitochondrial protein synthesis by charging tRNAs with their ...
https://www.ncbi.nlm.nih.gov/pubmed/23433712?dopt=Abstract
*  Synthetic Microcin C Analogs Targeting Different Aminoacyl-tRNA Synthetases | Journal of Bacteriology
First, the N-acyl O-aminopropylphosphoramidate linker of the aspartyl-adenylate moiety of processed McC (compound 2) was ... Aminoacyl-tRNA synthetases (aaRSs) carry out the condensation of genetically encoded amino acids with cognate tRNAs. When 1 of ... Synthetic Microcin C Analogs Targeting Different Aminoacyl-tRNA Synthetases. Pieter Van de Vijver, Gaston H. M. Vondenhoff, ... Synthetic Microcin C Analogs Targeting Different Aminoacyl-tRNA Synthetases. Pieter Van de Vijver, Gaston H. M. Vondenhoff, ...
https://jb.asm.org/content/191/20/6273?ijkey=4999336c8d9a69eb5ce7e1e67c1c4d7de4ac097c&keytype2=tf_ipsecsha
*  aminoacyl tRNA synthetase p18 component Summary Report | CureHunter
aminoacyl tRNA synthetase p18 component: shares a protein motif with the beta and gamma subunits of eukaryotic elongation ... factor 1; amino acid sequence given in first source ... Amino Acyl-tRNA Synthetases: 128*aminoacyl tRNA synthetase p18 ... aminoacyl tRNA synthetase p18 component. Subscribe to New Research on aminoacyl tRNA synthetase p18 component ... shares a protein motif with the beta and gamma subunits of eukaryotic elongation factor 1; amino acid sequence given in first ...
http://www.curehunter.com/public/keywordSummaryC101946-aminoacyl-tRNA-synthetase-p18-component.do
*  Aminoacyl-tRNA synthetases | definition of aminoacyl-tRNA synthetases by Medical dictionary
What is aminoacyl-tRNA synthetases? Meaning of aminoacyl-tRNA synthetases medical term. What does aminoacyl-tRNA synthetases ... Looking for online definition of aminoacyl-tRNA synthetases in the Medical Dictionary? aminoacyl-tRNA synthetases explanation ... aminoacyl-tRNA synthetases. Also found in: Dictionary, Thesaurus. a·mi·no·ac·yl-tRNA syn·the·tas·es. enzymes catalyzing the ... aminoacyl-tRNA. transfer RNA to which its specific amino acid has been coupled by its specific aminoacyl-tRNA synthetase. ...
https://medical-dictionary.thefreedictionary.com/aminoacyl-tRNA+synthetases
*  Codon usage, amino acid usage, transfer RNA and amino-acyl-tRNA synthetases in mimiviruses - PAR00011189 - Horizon
... tRNA) and amino acyl-tRNA synthetases. We confirmed that the codon and amino acid usages of these giant viruses are highly ... Codon usage, amino acid usage, transfer RNA and amino-acyl-tRNA synthetases in mimiviruses ... We further describe that the set of tRNAs and amino acyl-tRNA synthetases in mimiviruses is globally not adapted to the codon ... Colson P., Fournous G., Diene S. M., Raoult Didier. (2013). Codon usage, amino acid usage, transfer RNA and amino-acyl-tRNA ...
http://www.documentation.ird.fr/hor/PAR00011189
*  Predicted class-I aminoacyl tRNA synthetase-like proteins in non-ribosomal peptide synthesis | Biology Direct | Full Text
acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase. New_papain: novel family of papain-like cysteine proteases - ... tyrosine-tRNA synthetase. WTRS: tryptophan-tRNA synthetase. Gene and protein abbreviations: 2OGFEDO: 2-oxoglutarate and iron(II ... The least studied of these systems are those utilizing tRNAs or aminoacyl-tRNA synthetases (AAtRS) in non-ribosomal peptide ... tRNAs charged with the cognate amino acids by lysyl- or alanyl-tRNA synthetases are used by bacterial enzymes typified by ...
https://biologydirect.biomedcentral.com/articles/10.1186/1745-6150-5-48
*  Office of Science Outreach
tRNA-charging. Amino acyl-tRNA Synthetases carry out a two-step reaction involving ATP.. ...
http://www.indiana.edu/~oso/animations/An6.html
*  Plus it
... and amino acyl-tRNA synthetases (Mirande et al., 1985). eEF1A has been shown to colocalize with actin filaments in maize ... 1985) Association of an amino-acyl-transfer RNA synthetase complex and of phenylalanyl-transfer RNA synthetase with the ...
http://www.plantphysiol.org/content/116/4/1227
*  Methods for monitoring and measurement of protein translation in time and space - Molecular BioSystems (RSC Publishing) DOI:10...
... achieved via co-expression of an orthogonal amino acyl-tRNA synthetase/tRNA pair in specific cells. The pyrrolysyl-tRNA ... Amino acyl-tRNA synthetase: a family of enzymes which catalyze the covalent conjugation of specific amino acids to their ... bacterial amino acyl-tRNA synthetases have been engineered to have a higher affinity for given non-canonical amino acids, and ... due to the permissive nature of certain amino acyl-tRNA synthetases. After incorporation, these amino acids can be either ...
http://pubs.rsc.org/en/content/articlehtml/2017/mb/c7mb00476a
*  Purification of each component used in the reconstitute | Open-i
Amino Acyl-tRNA Synthetases/metabolism. *Binding Sites. *Cell-Free System. *DNA, Complementary/metabolism ... tRNAs. tRNAs (2 μg) were resolved by 8 m urea PAGE (12.5%) and stained with toluidine blue (TB). C, translation factors. eEF1s ... tRNAs. tRNAs (2 μg) were resolved by 8 m urea PAGE (12.5%) and stained with toluidine blue (TB). C, translation factors. eEF1s ... 4). These components were combined in a test tube with amino acids, triphosphate nucleotides (ATP, GTP, CTP, and UTP), and T7 ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4231674_zbc0491400990004&req=4
*  Regulation of the hetero-octameric ATP phosphoribosyl transferase complex from Thermotoga maritima by a tRNA synthetase-like...
Amino Acid Sequence. MESH. Amino Acyl-tRNA Synthetases/metabolism. MESH. Binding Sites. MESH. ... Common ancestry of the regulatory HisZ subunit and class II aminoacyl-tRNA synthetase may reflect the balanced need of ... the structure of the regulatory HisZ subunit is distantly related to class II aminoacyl-tRNA synthetases. However, neither the ... Regulation of the hetero-octameric ATP phosphoribosyl transferase complex from Thermotoga maritima by a tRNA synthetase-like ...
https://epub.uni-regensburg.de/13678/
*  Frontiers | Saudi Moumouvirus, the First Group B Mimivirus Isolated from Asia | Microbiology
The SDMV genome was predicted to encode 868 ORFs, ranging in size from 54 to 2,914 amino acids, with a mean size of 349 aa. ... The SDMV genome was predicted to encode 868 ORFs, ranging in size from 54 to 2,914 amino acids, with a mean size of 349 aa. ... transfer RNA and amino-acyl-tRNA synthetases in Mimiviruses. Intervirology 56, 364-375. doi: 10.1159/000354557 ... we observed an unusual set of aminoacyl-tRNA synthetase (aaRS), which are translation-related genes not found in viruses other ...
https://www.frontiersin.org/articles/10.3389/fmicb.2016.02029/full
*  The 2.0 A crystal structure of Thermus thermophilus methionyl-tRNA synthetase reveals two RNA-binding modules. - Semantic...
RESULTS We determined the crystal structure of the class Ia methionyl-tRNA synthetase (MetRS) at 2.0 A resolution, using MetRS ... No conserved structural features for tRNA recognition by class I synthetases have been established. ... and arginyl-tRNA synthetases. The beta-alpha-alpha-beta-alpha topology domain, which can now be identified in all known ... structures of the class Ia and Ib synthetases, is likely to dock with the inner side of the L-shaped tRNA, thereby positioning ...
https://www.semanticscholar.org/paper/The-2.0-A-crystal-structure-of-Thermus-thermophilus-Sugiura-Nureki/775807248451993607f8c117a8b88c8da6e1b757
*  HF interacts with both the site for amino acid activati | Open-i
HF interacts with both the site for amino acid activation and the site for docking the 3′-end of tRNAa, Thermal melting19 of ... Amino Acyl-tRNA Synthetases/antagonists & inhibitors/chemistry*/metabolism*. *Piperidines/chemistry*/metabolism*/pharmacology ... ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase. ... ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase. ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3569068_nihms-420657-f0003&req=4
*  Life | Free Full-Text | Is Research on "Synthetic Cells" Moving to the Next Level? | HTML
36 proteins (20 amino acyl-tRNA synthetase, 10 translation factors, 4 energy-related enzymes, T7 RNA polymerase, methionine ... Hong, S.H.; Kwon, Y.-C.; Jewett, M.C. Non-standard amino acid incorporation into proteins using Escherichia coli cell-free ... Dong, H.; Nilsson, L.; Kurland, C.G. Co-variation of tRNA abundance and codon usage in Escherichia coli at different growth ...
https://www.mdpi.com/2075-1729/9/1/3/htm
*  The significance of translation regulation in the stress response | BMC Genomics | Full Text
... and amino acyl tRNA synthetases (AspS, LeuS, LysS, MetS, PheT, ProS, ThrS and TrpS). The genes for RpsS, PepP and PrfC were in ... and amino acyl tRNA synthetases (alaS, aspS, hisS, leuS, lysS, pheS, pheT, proS, thrS and valS)], transcription [genes related ... translation factors and amino acyl tRNA synthetases. We have demonstrated here that these genes were down-regulated, at the ... Under a low availability of an amino acid, higher density could result from ribosome congestion near the codons of this amino ...
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-14-588
*  Find Research Outputs - Vrije Universiteit Amsterdam
Bi-allelic Mutations in EPRS, Encoding the Glutamyl-Prolyl-Aminoacyl-tRNA Synthetase, Cause a Hypomyelinating Leukodystrophy. ...
https://research.vu.nl/en/publications/?format=&page=8
*  exam 1 questions and review
A. Amino acyl tRNA synthetase attaches the correct amino acid to the correct tRNA in a two-step reaction. First, the amino acid ... 3. amino acid attachment to 3'end C. amino-acyl-tRNA synthetase 1. catalyzes attachment of amino acid to either the 2' or 3' ... both tRNAs lean over such that the P site tRNA has its 3' end at the E site (P/E orientation) and the A site tRNA has its amino ... Then AMP is removed from the amino acid and the amino acid is linked to the 3' end of the tRNA at either the 2' or 3' OH of the ...
http://www1.udel.edu/biology/fschmieg/exam1qr.htm
*  Search Results
Translation; Amino acyl tRNA synthetases and tRNA modification Pathway: pathway table. Secondary Evidence:. Hagervall TG, ... Residues 29 to 383 (E-value = 4.8e-215) place HD0389 in the tRNA_Me_trans family which is described as tRNA methyl transferase ... tRNA (5-methylaminomethyl-2-thiouridylate) methyltransferase. Gene Start:. 308366. Gene Stop:. 309532. Gene Length:. 1167. ... Residues 29-160 are 79% similar to a (TRNA METHYLTRANSFERASE) protein domain (PD000352) which is seen in TRMU_HAEIN.. Paralogs: ...
http://stdgen.northwestern.edu/cgi-bin/gene_id_search.cgi?dbname=hduc&gene_id=HD0389
*  Fukunaga, R.<...
Amino Acyl-tRNA Synthetases Medicine & Life Sciences Proteins Medicine & Life Sciences Transfer RNA Medicine & Life Sciences ... A SelB/EF-Tu/aIF2γ-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNACys Yanagisawa, T., Ishii, ...
https://jhu.pure.elsevier.com/en/persons/ryuya-fukunaga