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Alternative Splicing Modes  Alternative Splicing Modes
Are you looking for more information on alternative splicing modes? If so, read on to learn more about this basic genetics ... In this alternative splicing mode, a sequence may be simply retained or spliced out as an intron. This differs from the exon ... Alternative Donor Site. In this mode, a donor site, an alternative 5' splice junction, is used. This changes the 3' boundary of ... Alternative splicing, also referred to as differential splicing, is a process where the RNA exons of the RNA that is produced ...
more infohttp://www.brighthub.com/science/genetics/articles/89429.aspx
Alternative splicing  Alternative splicing
Protein for which at least two isoforms exist due to distinct pre-mRNA splicing events. ...
more infohttp://www.uniprot.org/keywords/25
Alternative splicing - Wikipedia  Alternative splicing - Wikipedia
Research Group dealing with alternative Splicing issues and mis-splicing in human diseases Alternative Splicing of ion channels ... Since then, alternative splicing has been found to be ubiquitous in eukaryotes. The "record-holder" for alternative splicing is ... These databases are useful for finding genes having pre-mRNAs undergoing alternative splicing and alternative splicing events. ... A General Definition and Nomenclature for Alternative Splicing Events at SciVee AStalavista (Alternative Splicing landscape ...
more infohttps://en.wikipedia.org/wiki/Alternative_splicing
Alternative splicing: current perspectives.  - PubMed - NCBI  Alternative splicing: current perspectives. - PubMed - NCBI
Do similar forces act on all types of alternative splicing? Are the products generated by alternative splicing functional? Why ... Alternative splicing: current perspectives.. Kim E1, Goren A, Ast G.. Author information. 1. Department of Human Molecular ... Alternative splicing is a well-characterized mechanism by which multiple transcripts are generated from a single mRNA precursor ... By allowing production of several protein isoforms from one pre-mRNA, alternative splicing contributes to proteomic diversity. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/18081010?dopt=Abstract
Alternative Spliced Transcripts as Cancer Markers  Alternative Spliced Transcripts as Cancer Markers
This process can lead to transcript diversification through the phenomenon of alternative splicing. Alternative splicing can ... Alternative Spliced Transcripts as Cancer Markers. Otavia L. Caballero,2 Sandro J. de Souza,2 Ricardo R. Brentani,1,2 and ... The effect of alternative splicing in expanding protein repertoire might partially underlie the apparent discrepancy between ... Many cancer-associated genes, such as CD44 and WT1 are alternatively spliced. Variation of the splicing process occurs during ...
more infohttps://www.hindawi.com/journals/dm/2001/184856/abs/
Alternative splicing annotation project - Wikipedia  Alternative splicing annotation project - Wikipedia
Alternative Splicing Annotation Project (ASAP) is a database for alternative splicing data. The purpose of this project was to ... Lee, C., Atanelov, L., Modrek, B., & Xing, Y. (2003). ASAP: the alternative splicing annotation project. Nucleic Acids Research ... analysis and comparative genomics of alternative splicing in 15 animal species". Nucleic Acids Res. England. 35 (Database issue ... AspicDB RNA splicing Kim, Namshin; Alekseyenko Alexander V; Roy Meenakshi; Lee Christopher (Jan 2007). "The ASAP II database: ...
more infohttps://en.wikipedia.org/wiki/Alternative_splicing_annotation_project
GitHub - HussainAther/awesome-alternative-splicing: Alternative splicing resource  GitHub - HussainAther/awesome-alternative-splicing: Alternative splicing resource
Contribute to HussainAther/awesome-alternative-splicing development by creating an account on GitHub. ... awesome-alternative-splicing. What is this?. This is a resource for software and information about alternative splicing. ... Alternative 5' splice site (A5SS): An alternative 5' splice junction (donor site) is used that changes the 3' boundary of the ... Alternative 3' splice site (A3SS): An alternative 3' splice junction (acceptor site) is used that changes the 5' boundary of ...
more infohttps://github.com/HussainAther/awesome-alternative-splicing
Alternative splicing, an important mechanism for cancer | EurekAlert! Science News  Alternative splicing, an important mechanism for cancer | EurekAlert! Science News
Therefore, the study of alternative splicing opens new doors in the research to cure cancer and may provide new alternatives to ... Alternative splicing, an important mechanism for cancer Scientists discover several alterations in this cellular process with ... "Changes in alternative splicing provide cancer with new ways in which it can escape fine cellular regulation. ... "With this new study, we have discovered that changes in alternative splicing that occur in cancer impact protein functions in a ...
more infohttps://www.eurekalert.org/pub_releases/2017-09/spmd-asa092117.php
Global regulation of alternative splicing during myogenic differentiation.  - PubMed - NCBI  Global regulation of alternative splicing during myogenic differentiation. - PubMed - NCBI
Global regulation of alternative splicing during myogenic differentiation.. Bland CS1, Wang ET, Vu A, David MP, Castle JC, ... Recent genome-wide analyses have elucidated the extent of alternative splicing (AS) in mammals, often focusing on comparisons ... C) Summary of the different types of validated splicing transitions included within the data set of 117 splicing transitions. ( ... Clusters of splicing transitions with similar temporal patterns exhibit enrichment of specific motifs. Splicing transitions ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/20634200
Alternative splicing | Journal of Cell Science  Alternative splicing | Journal of Cell Science
How alternative splicing affects membrane-trafficking dynamics R. Eric Blue, Ennessa G. Curry, Nichlas M. Engels, Eunice Y. Lee ... miRNA targeting and alternative splicing in the stress response - events hosted by membrane-less compartments Mariya M. ... CCAR-1 affects hemidesmosome biogenesis by regulating unc-52/perlecan alternative splicing in the C. elegans epidermis Rong Fu ... Summary: Loss of CCAR-1 function during C. elegans embryogenesis results in dysregulated alternative splicing of unc-52 (the ...
more infohttp://jcs.biologists.org/keyword/alternative-splicing
JCVI: Gene and Alternative Splicing Annotation With AIR  JCVI: Gene and Alternative Splicing Annotation With AIR
... such as alternative splicing. We present a methodology for the automated annotation of genes and their alternatively spliced ... and combines the traditionally distinct gene annotation and alternative splicing detection processes in a comprehensive and ... At the core of the method is the splice graph, a compact representation of a gene, its exons, introns, and alternatively ... spliced isoforms. The putative transcripts are enumerated from the graph and assigned confidence scores based on the strength ...
more infohttp://www.jcvi.org/cms/publications/listing/abstract/article/gene-and-alternative-splicing-annotation-with-air/
Frontiers | Depolarization-Mediated Regulation of Alternative Splicing | Neuroscience  Frontiers | Depolarization-Mediated Regulation of Alternative Splicing | Neuroscience
... we will summarize how splicing regulators change and affect alternative splicing in this process. We will also discuss a novel ... we will summarize how splicing regulators change and affect alternative splicing in this process. We will also discuss a novel ... The significance of the dynamic control of alternative splicing in response to changes of calcium levels has been largely ... The significance of the dynamic control of alternative splicing in response to changes of calcium levels has been largely ...
more infohttps://www.frontiersin.org/articles/10.3389/fnins.2011.00141/full
alternative splicing | Biochemical Society Transactions  alternative splicing | Biochemical Society Transactions
Tra2 protein biology and mechanisms of splicing control Andrew Best, Caroline Dalgliesh, Mahsa Kheirollahi-Kouhestani, Marina ... Functional impact of splice isoform diversity in individual cells Karen Yap, Eugene V. Makeyev ...
more infohttp://www.biochemsoctrans.org/keyword/alternative-splicing
Genomic Research - RNA Alternative Splicing, Genetic Disorders and Protein Synthesis  Genomic Research - RNA Alternative Splicing, Genetic Disorders and Protein Synthesis
RNA alternative splicing was first noticed in adenoviruses in the 1970s. The researchers noticed that adenoviruses produced two ... Find out more about the role of RNA and RNA alternative splicing in protein synthesis and genetic disorders. ... Importance of RNA Alternative Splicing. RNA alternative splicing enables genetic efficiency and genetic diversity. On the ... RNA Alternative Splicing. First let us understand what splicing is. DNA directs the synthesis or production of RNA. This is ...
more infohttps://www.brighthub.com/science/genetics/articles/47494.aspx
alternative splicing, a process that yields different protein products  alternative splicing, a process that yields different protein products
English to French translation of alternative splicing, a process that yields different protein products [DNA - Science (general ... alternative splicing, a process that yields different protein products. However, it's now believed that the incredible ... alternative splicing, a process that yields different protein products. French translation: épissage alternatif. ... "alternative splicing" (a process that yields different protein products* from the same gene),. ...
more infohttps://www.proz.com/kudoz/english_to_french/science_general/885970-alternative_splicing_a_process_that_yields_different_protein_products.html
Regulation of CD45 alternative splicing by HNRPLL  Regulation of CD45 alternative splicing by HNRPLL
Research Topics about Regulation of CD45 alternative splicing by HNRPLL ... alternative splicing*antigens*formal social control*tyrosine*memory*antigen receptors*signal transduction*ribonucleoproteins* ... Regulation of CD45 alternative splicing by HNRPLL. Summary. Principal Investigator: Anjana Rao ... Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL. Shalini Oberdoerffer. Department of ...
more infohttp://www.labome.org/grant/r01/ai/regulation/of/regulation-of-cd45-alternative-splicing-by-hnrpll-8436128.html
Comparative Cross-Species Alternative Splicing in Plants | Plant Physiology  Comparative Cross-Species Alternative Splicing in Plants | Plant Physiology
... splice donor sites, alternative 3′ splice acceptor sites, and intron retention. AS patterns are represented by (top and bottom ... alternative splice sites. Taken together, these results indicate that EPGA can faithfully report genome-wide splicing events ... Comparative Cross-Species Alternative Splicing in Plants Message Subject (Your Name) has sent you a message from Plant ... Comparative Cross-Species Alternative Splicing in Plants. Hadas Ner-Gaon, Noam Leviatan, Eitan Rubin, Robert Fluhr ...
more infohttp://www.plantphysiol.org/content/144/3/1632
JCI -
Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis  JCI - Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis
Mechanistic characterizations indicated that SETD2 downregulation affects the alternative splicing of a subset of genes ...
more infohttps://www.jci.org/articles/view/94292/pdf
JCI -
Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis  JCI - Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis
rMATS: robust and flexible detection of differential alternative splicing from replicate RNA-Seq data. Proc Natl Acad Sci U S A ... Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense? Trends Biochem Sci. 2008;33(8 ... A slow RNA polymerase II affects alternative splicing in vivo. Mol Cell. 2003;12(2):525-532.. View this article via: PubMed ... Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis. Huairui Yuan,1 Ni Li,1 Da ...
more infohttps://www.jci.org/articles/view/94292
IJMS | Free Full-Text | Linking Endoplasmic Reticular Stress and Alternative Splicing  IJMS | Free Full-Text | Linking Endoplasmic Reticular Stress and Alternative Splicing
Meanwhile some early splicing changes are supplanted by new splicing changes introduced by the up-regulation of ELL2, a ... Some of the ,4000 splicing changes seen at 18 h after LPS stimulation persist into the late stages of antibody secretion, up to ... Inhibition of the mRNA-degradation function of Ire1 is correlated with further differences in the splicing patterns and a ... The mRNA-modifying function of phosphorylated Ire1 non-canonically splices Xbp1 mRNA and yet degrades other cellular mRNAs with ...
more infohttps://www.mdpi.com/1422-0067/19/12/3919
Alternative splicing takes control of cytokine signaling  Alternative splicing takes control of cytokine signaling
Even so, little of this active cytokine is made as alternative splicing favors the expression of the inactive isoforms or ... Overall, our data show that alternative splicing is an important response to pathogen sensing and infection that efficiently ... In the case of IFNλ4, alternative splicing suppresses protein expression and secretion to prevent its antiviral activity. ... Here, we present findings demonstrating that alternative splicing tailors IL-22BP activity to specific spatiotemporal ...
more infohttps://digital.lib.washington.edu/researchworks/handle/1773/37154
Microenvironment regulation of VEGF alternative splicing in malignancy | Cancer Research  Microenvironment regulation of VEGF alternative splicing in malignancy | Cancer Research
Microenvironment regulation of VEGF alternative splicing in malignancy Message Subject (Your Name) has forwarded a page to you ... Microenvironment regulation of VEGF alternative splicing in malignancy. Ana Paula Elias and Sergio Dias ... Serine/arginine rich (SR) proteins, that are described to be involved in alternative splicing, are also up-regulated in pH5,5. ... To investigate the specific SR proteins involved in VEGF splicing, we used siRNA to block separately some SR proteins that have ...
more infohttp://cancerres.aacrjournals.org/content/67/9_Supplement/1368
British Library EThOS: Analysis of CD45 variants effecting alternative splicing  British Library EThOS: Analysis of CD45 variants effecting alternative splicing
The exon 4 77G allele is present at a low frequency in Caucasoids and prevents splicing from high to low molecular weight ... The exon 6 138G allele is found at a high frequency in Far Eastern populations and promotes splicing towards low molecular ...
more infohttps://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.416455