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*  The Ins and Outs of Adipose Tissue
... Olivecrona, Thomas Umeå University, Faculty of Medicine, Department of Medical Biosciences ... Intracellular lipolysis is initiated by adipose tissue triglyceride lipase (ATGL) which hydrolyzes triglycerides to ... The overriding control of how Much gets deposited in the tissue as triglyceride and how much spills over into blood as albumin- ... this chapter is to discuss what mechanisms are available to rapidly modulate fatty acid uptake/mobilization in adipose tissue. ...
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*  DiVA - Search result
This may promote adipose tissue growth in early age. The data indicate that age-dependent variation in basal and insulin- ... The regulation of adipocyte metabolism is of importance for adipose tissue growth and therefore also for the development of ... Skin tissue growth into the implant was delayed in one case and one patient had impaired healing between intestine and the ... An ex vivo model using human peritoneum to explore mesh-tissue integration2017In: Biology open, ISSN 2046-6390, Vol. 6, no 9, p ...
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*  Dysregulation of the autonomic nervous system can be a link between visceral adiposity and insulin resistance
Abdominal adipose tissue distribution was determined with computed tomography.. Male relatives had decreased testosterone ... The amount of visceral adipose tissue (VAT) was associated with insulin resistance and with heart rate at rest and during ... Computed tomography was performed in a subgroup (n = 9 + 9) to determine abdominal adipose tissue distribution. RESULTS: R ... OBJECTIVE: To evaluate the interplay among abdominal adipose tissue distribution, the cortisol axis, the autonomic nervous ...
http://umu.diva-portal.org/smash/record.jsf?pid=diva2:153793
*  Peroxisome proliferator-activated receptor activation favours selective subcutaneous lipid deposition by coordinately...
adipose tissue, fat redistribution, fatty acid transport, lipoprotein lipase, peroxisome proliferator- tivated receptor, ... Methods: We evaluated herein triglyceride-derived lipid incorporation into adipose tissue depots, LPL mass and activity, mRNA ... and the expression/activity of enzymes defining adipose tissue lipogenic potential in rats treated with the PPARγ ligand ...
http://umu.diva-portal.org/smash/record.jsf?pid=diva2:950220
*  Cortisol metabolism after weight loss : associations with 11 beta-HSD type 1 and markers of obesity in women
Cortisol metabolites correlated with 11-HSD type 1 activity in abdominal subcutaneous adipose tissue. The ratio of cortisol to ... body composition including regional adipose tissue depots and insulin resistance by HOMA-IR before and 2years after gastric ... metabolite excretion and enhanced expression and activity of 11-hydroxysteroid dehydrogenase type 1 in adipose tissue are ... but also favourably decreases the global and tissue-specific activity of the cortisol-activating enzyme 11 -HSD type 1, ...
http://umu.diva-portal.org/smash/record.jsf?pid=diva2:629538
*  Sex differences in depot-specific lipolysis regulation in human adipocytes : interplay between adrenergic stimulation,...
adipose tissue, cAMP, glucocorticoids, glucose, insulin, insulin resistance, lipolysis, subcutaneous fat, type 2 diabetes, ... In adipose biopsies from subjects undergoing abdominal surgery, we found that glucose uptake capacity was elevated in omental ... Open this publication in new window or tab ,,Interplay between hormones, nutrients and adipose depots in the regulation of ... The aim of this study was to elucidate the interplay between hormones, nutrients and adipose depots in normal and insulin- ...
http://umu.diva-portal.org/smash/record.jsf?pid=diva2:144211
*  DiVA - Søkeresultat
Association of adipose tissue blood flow with fat depot sizes and adipokines in women2012Inngår i: International Journal of ... Objective: To explore possible associations between adipose tissue (AT) blood flow (ATBF), AT depot sizes and adipocyte-derived ... The TH-positive innervation of co-grafts was sparse when the striatal co-grafts were derived from the Gdnf(-/-) tissue while ... tissue. In contrast, lack of GDNF in the VM portion of co-grafts had no effect on the survival of TH-positive neurons when co- ...
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*  DiVA - Search result
AACS gene expression is particularly abundant in white adipose tissue, as it is induced during adipocyte differentiation. In ... Intracranial volume reflects the maximally attained brain size during development, and remains stable with loss of tissue in ... This type of direct conversion is presumably occurring in non-neuronal tissue. Furthermore, KCl-evoked dopamine releases were ... In the cytosol of lipogenic tissue, ketone bodies are activated by AACS (acetoacetyl-CoA synthetase) and incorporated into ...
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*  DiVA - Search result
AACS gene expression is particularly abundant in white adipose tissue, as it is induced during adipocyte differentiation. In ... VEGF-mRNA was detected in the investigated tissue, with the reactions being more clearly detected in the tendon tissue with ... They travel from bone marrow stem cells into damaged tissues, suggesting that they can repair tissue injuries without directly ... Therefore, it would be of interest to know if there is a local SP-supply in tendon tissue. In the present study, the patterns ...
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*  Inflammatory markers in serum and adipose tissue in relation to markers of sub-clinical atherosclerosis in rheumatoid arthritis...
Production of cytokines, i.e., adipokines, in the adipose tissue could link the inflammation with the CV system. Control of the ... Inflammatory markers in serum and adipose tissue in relation to markers of sub-clinical atherosclerosis in rheumatoid arthritis ... adipose tissue, tumor necrosis factor inhibition National Category Rheumatology and Autoimmunity Identifiers. urn:nbn:se:umu: ... The result from a factor analysis indicated IL-1Ra to be associated with both adipose tissue and inflammation. Levels of s- ...
http://umu.diva-portal.org/smash/record.jsf?pid=diva2:543795
*  Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury
Angptl4 mRNA levels were increased by ninefold in liver and kidney tissue and by twofold in adipose tissue of CP-treated mice. ... CP caused a 40% reduction in epididymal white adipose tissue (WAT) mass, with a reduction of LPL expression and activity. CP ... CP also increased TG accumulation in kidney tissue, which was ameliorated by PPAR alpha ligand. In summary, a PPAR alpha ligand ... blots of two-dimensional gel electrophoresis identified increased expression of a neutral pI Angptl4 protein in kidney tissue ...
http://umu.diva-portal.org/smash/record.jsf?pid=diva2:565659
*  Benefits of a Paleolithic diet with and without supervised exercise on fat mass, insulin sensitivity, and glycemic control : a...
However, to distinguish insulin sensitivity of different tissues like skeletal muscle, liver and adipose tissue, the ... Our present results indicate reduced metabolic flexibility in the fat content in liver and muscle tissue among patient with ...
http://umu.diva-portal.org/smash/record.jsf?pid=diva2:1010242
*  Inactivation of lipoprotein lipase occurs on the surface of THP-1 macrophages where oligomers of angiopoietin-like protein 4...
... triglycerides in plasma lipoproteins causing release of fatty acids for metabolic purposes in muscles and adipose tissue. LPL ...
http://umu.diva-portal.org/smash/record.jsf?pid=diva2:559139
*  DiVA - Search result
Long term effects of a diet intervention on adipose tissue blood flow, heart rate variability and endothelial function: a ... and normal healthy tissue (n=98) when studying a multivariate parameter set. Both the tumour tissue and normal tissue groups ... In a prostate tissue slice with mostly normal healthy tissue, the anterior side was significantly harder (p-value , 0.05) as ... Prostate tissue stiffness as measured with a resonance sensor system: a study on silicone and human prostate tissue in vitro. ...
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*  DiVA - Search result
Adipose tissue expresses pro-inflammatory molecules including tumour necrosis factor (TNF), and levels of TNF are also related ...
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*  DiVA - Search result
Human MSCs from adipose tissue (ASCs) and bone marrow (BMSCs) were cultured in Minimum Essential Medium-alpha (alpha-MEM) ... Binding of tissue plasminogen activator to endothelial cells. The effect on functional properties. Localization of a ligand in ... The binding of 125I-labelled tissue plasminogen activator (tPA), the tPA A- or B-chain to endothelial cells (EC) were studied ... Transplanted rMSC induced up-regulation of vascular endothelial growth factor in spinal cord tissue rostral to the injury site ...
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*  DiVA - Search result
A model of metabolic syndrome with five composite factors, based on 14 variables including markers produced by adipose tissue ... We investigated whether elevated antigen levels of tissue plasminogen activator (tPA), plasminogen activator inhibitor-1 (PAI-1 ...
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*  Schwann cell strip for peripheral nerve repair
The results of in vitro experiments indicate adipose tissue contains a pool of regenerative stem cells which can be ... adipose stem cells, cell matrix, fibrin, nerve conduit, nerve gap HSV kategori Forskningsprogram kirurgi Identifikatorer. urn: ... Adipose derived stem cells (ASC) are found in abundant quantities. In this thesis the ability of rat ASC to differentiate into ... Peripheral nerve injuries are often associated with loss of nerve tissue and require autologous nerve grafts to provide a ...
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*  DiVA - Søkeresultat
Human MSCs from adipose tissue (ASCs) and bone marrow (BMSCs) were cultured in Minimum Essential Medium-alpha (alpha-MEM) ... In the tissue of the target area, in which loose connective tissue and fat cells were frequent constituents, there was a ... VEGF-mRNA was detected in the investigated tissue, with the reactions being more clearly detected in the tendon tissue with ... The subepithelial loose connective tissue contains vessels, nerves, and connective tissue cells, among these mast cells. The ...
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