Loading...
*  Plus it
In addition, adipose tissue transcriptome was determined by microarray. B: The x-axis shows the change in percentage FA in VLDL ... Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake. Prog Lipid Res 2008; ... At these visits, IHTG content was determined by 1H-MRS, hepatic DNL from 2H2O enrichment in VLDL-TG palmitate, adipose tissue ... Adipose tissue lipolysis and hepatic de novo lipogenesis (DNL) are the main pathways contributing to IHTG. We hypothesized that ...
http://care.diabetesjournals.org/content/41/8/1732
*  Effective Exercise Modality to Reduce Insulin Resistance in Women With Type 2 Diabetes | Diabetes Care
Adipose tissue areas.. The loss in total abdominal AT cross-sectional area was greater in the Ae+RT group than the control ... A second objective was to relate the improved insulin sensitivity to changes in abdominal adipose tissue (AT) and thigh muscle ... Treuth M, Hunter GR, Kekes-Szabo, Weinsier RL, Goran MI, Berland L, Reduction in intra-abdominal adipose tissue after strength ... Ross R, Rissanen J: Mobilization of visceral and subcutaneous adipose tissue in response to energy restriction and exercise. Am ...
http://care.diabetesjournals.org/content/26/11/2977.full
*  Plus it
Adipose Tissue and Muscle. There was no difference in either visceral adipose tissue or subcutaneous adipose tissue areas ... 285.4 ± 24.7 cm2, P = 0.40). Both visceral and subcutaneous adipose tissue areas decreased after the VLCD and then remained ... This finding supports the concept of a personal fat threshold above which adipose tissue cannot store the available ... The observed fall in pancreas fat is a secondary consequence of decreased tissue delivery of triglyceride. ...
http://care.diabetesjournals.org/content/39/5/808
*  Plus it
The contribution of adipose tissue to adipokine levels. The correlations between fat mass and adipokines are shown in Table 3. ... Spearman correlation coefficients between adipose tissue and adipokine levels in nondiabetic populations with and without ... suggest that these women are more insulin resistant due in part to their tendency to accumulate adipose tissue in the truncal ... First Nation women had significantly greater total fat mass than white women and a greater proportion of their adipose mass as ...
http://care.diabetesjournals.org/content/30/2/286
*  Adipose Tissue Lipolysis Is Upregulated in Lean and Obese Men During Acute Resistance Exercise | Diabetes Care
Limited information exists regarding the effect of resistance exercise on adipose tissue lipolysis. We monitored adipose tissue ... Adipose tissue TGLA (Fig. 1) peaked at 5 min in the lean men (rising from 0.32 ± 0.27 to 5.82 ± 1.32 mmol · kg−1 · min−1) and ... Resistance exercise elevated adipose tissue TGLA 16- to 18-fold within 5-10 min in the lean and obese men and increased energy ... Adipose tissue and blood were sampled during exercise for TGLA, metabolite, and hormone determinations. Respiratory exchange ...
http://care.diabetesjournals.org/content/31/7/1397
*  Diabetes Research and Care Through the Ages | Diabetes Care
Adipose tissue plasticity. Gut factors (including the microbiome). Organ level. 9. 5. ...
http://care.diabetesjournals.org/content/40/10/1302.figures-only
*  Plus it
1). In adipose tissue biopsies from the abdominal wall of the same patients in late pregnancy, we also confirmed that IRS-1 is ... Insulin signaling proteins, IR, IRS-1, and p85α were analyzed by Western blot in skeletal muscle (A-C) and adipose tissue (D-F ... In adipose tissue, the lipogenic transcription factor PPAR-γ declines in obese women during pregnancy and may shift genes in ... INSULIN RESISTANCE IN ADIPOSE TISSUE: IMPLICATIONS FOR EXCESS FUELS AND THE ORIGINS OF INSULIN RESISTANCE-. Unlike in skeletal ...
http://care.diabetesjournals.org/content/30/Supplement_2/S112
*  Plus it
Adipose tissue, inflammation and atherosclerosis. J Atheroscler Thromb 2010;17:332-341pmid:20124732. ... Adipose tissue inflammation has mainly been attributed to inflammatory processes observed in visceral and/or ectopic fat ... Obesity-induced inflammatory changes in adipose tissue. J Clin Invest 2003;112:1785-1788pmid:14679172. ... 30) demonstrated that visceral but not subcutaneous adipose tissue mass is associated with insulin resistance independent of ...
http://care.diabetesjournals.org/content/36/2/276
*  Plus it
... adipose tissue defects lead to ectopic lipid accumulation in other tissues such as liver (25). These considerations suggest ... Inflammation and adipose tissue macrophages in lipodystrophic mice. Proc Natl Acad Sci U S A 2010;107:240-245pmid:20007767. ... Adipose tissue as a buffer for daily lipid flux. Diabetologia 2002;45:1201-1210pmid:12242452. ... Lipodystrophies: disorders of adipose tissue biology. Biochim Biophys Acta 2009;1791:507-513. ...
http://care.diabetesjournals.org/content/36/8/2247
*  Plus it
In this large sample of adipose tissue biopsies, we show for the first time that patients with type 2 diabetes have fewer ... Adipose tissue cellularity in human obesity. Clin Endocrinol Metab 1976; 5: 299- 311. ... There is a growing appreciation that adipose tissue dysfunction in type 2 diabetes is due in part to adipocyte hypertrophia. ... RESEARCH DESIGN AND METHODS Abdominal subcutaneous adipose tissue was obtained from lean and obese subjects with or without ...
http://care.diabetesjournals.org/content/32/5/900
*  Plus it
Phillip Scherer (Dallas, TX) stated, "We've made the transition of adipose tissue from flubber to endocrine tissue." There are ... The role of adipose tissue and lipotoxicity in the pathogenesis of type 2 diabetes. Curr Diab Rep 2010;10:306-315. ... The relative adipose tissue vascular density is reduced in ob/ob mice, with evidence of areas of ischemia. In a study with ... Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. ...
http://care.diabetesjournals.org/content/34/9/e140
*  Plus it
No associations were seen for subcutaneous adipose tissue.. CONCLUSIONS Measurement of visceral adipose tissue depth in early ... A visceral adipose tissue depth above the upper quartile value was significantly associated with a positive GCT in later ... The risk of having a positive GCT (≥7.8 mmol/l) was determined in association with subcutaneous and visceral adipose tissue ... 6) to measure subcutaneous and visceral abdominal adipose tissue. A total of 62 patients were scanned on a Philips iU22 ...
http://care.diabetesjournals.org/content/32/7/1308
*  Diabetes and Cancer | Diabetes Care
As recently reviewed, adipose tissue is an active endocrine organ producing free fatty acids, interleukin-6 (IL-6), monocyte ... Obesity and cancer: the role of dysfunctional adipose tissue. Cancer Epidemiol Biomarkers Prev 2009; 18: 2569-2578. ... The assumption that in the setting of insulin resistance of classic insulin target organs (liver, muscle, adipose tissue) at ... Increases in body weight during adulthood largely reflect increases in adipose tissue rather than lean mass, so total body fat ...
http://care.diabetesjournals.org/content/33/7/1674.full
*  Plus it
Adipose tissue could be a mediator in the relationship. Obesity, particularly visceral fat, contributed the most to the ... Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB: The expression of tumor necrosis factor in human adipose tissue: ... Hill JO, Sidney S, Lewis CE, Tolan K, Scherzinger AL, Stamm ER: Racial differences in amounts of visceral adipose tissue in ... TNF-α is overexpressed in the adipose and muscle tissues of obese and insulin-resistant nondiabetic subjects, and this ...
http://care.diabetesjournals.org/content/29/8/1902
*  Accuracy of the 5-Day FreeStyle Navigator Continuous Glucose Monitoring System | Diabetes Care
Differences in adipose tissue blood flow observed in subjects with different BMI values may also contribute to the apparent ... Larsen O, Lassen N, Quaade F: Blood flow through human adipose tissue determined with radioactive xenon. Acta Physiol Scand 66: ... Horejsi R, Moller R, Pieber TR, Wallner S, Sudi K, Reibnegger G, Tafeit E: Differences of subcutaneous adipose tissue ... Moberg E, Hagstrom-Toft E, Arner P, Bolinder J: Protracted glucose fall in subcutaneous adipose tissue and skeletal muscle ...
http://care.diabetesjournals.org/content/30/5/1125.long
*  Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes...
Adipose tissue distribution was assessed using whole-body MRI; images were analyzed by a blinded investigator using sliceOmatic ... Peripheral effects of the endocannabinoid system in energy homeostasis: adipose tissue, liver and skeletal muscle. Rev Endocr ... adipose tissue distribution, appetite, markers of inflammation, markers of vascular function, gut hormones, circulating ...
http://care.diabetesjournals.org/content/39/10/1777.long
*  Plus it
Adipose tissue distribution was assessed using whole-body MRI; images were analyzed by a blinded investigator using sliceOmatic ... Peripheral effects of the endocannabinoid system in energy homeostasis: adipose tissue, liver and skeletal muscle. Rev Endocr ... adipose tissue distribution, appetite, markers of inflammation, markers of vascular function, gut hormones, circulating ...
http://care.diabetesjournals.org/content/39/10/1777
*  Plus it
Growth of human adipose tissue has been thought to be regulated by adipogenesis in youth, with subsequent fat expansion only by ... Obesity and polymorphisms in genes regulating human adipose tissue. Int J Obes (Lond) 2007; 31: 1629- 1641. ... They reduced PGC-1β expression with targeted antisense oligonucleotides in the liver and adipose tissue of rats fed high- ... Lipid oxidation was lower with the high-CHO diet, which was associated with higher adipose tissue uncoupling protein-2 ...
http://care.diabetesjournals.org/content/32/5/e48
*  Plus it
MicroRNA regulatory networks in human adipose tissue and obesity. Nat Rev Endocrinol 2015;11:276-288pmid:25732520. ... Surgery-induced weight loss is associated with the downregulation of genes targeted by microRNAs in adipose tissue. J Clin ... and adipose tissue metabolic function). Moreover, we examined the relationship of our candidate ex-RNAs with circulating ... focusing on adipose tissue distribution and function, metabolite profiles, gut microbial diversity, and epigenetic and genetic ...
http://care.diabetesjournals.org/content/40/4/546
*  Plus it
Adipose tissue as a buffer for daily lipid flux. Diabetologia 2002;45:1201-1210. ...
http://care.diabetesjournals.org/content/33/8/1831
*  Plus it
Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007; 117: 175- 184. ... thereby contributing to obesity-induced adipose tissue inflammation and insulin resistance (1). Expression of both M1 and M2 ... when infiltrated into obese adipose tissue, exhibit a phenotypic switch from M2 to M1 polarization, ...
http://care.diabetesjournals.org/content/33/1/e7
*  Plus it
... as well as adipose tissue metabolism (75) through the SCFA receptors GPR43 and GPR41 in adipose tissue and liver. ... the subjects on the CHOICE diet showed decreased adipose cytokine expression, increased maternal adipose tissue insulin ... Regulation of adipokine production in human adipose tissue by propionic acid. Eur J Clin Invest 2010;40:401-407pmid:20353437. ... Propionic acid affects immune status and metabolism in adipose tissue from overweight subjects. Eur J Clin Invest 2012;42:357- ...
http://care.diabetesjournals.org/content/38/8/1402
*  Plus it
Adipose tissue insulin resistance in adolescents with and without type 2 diabetes. Pediatr Obes 2014;9:373-380pmid:23861170. ... but this approach did not explore differences in tissue-specific responses to insulin between youth and adults. Third, we used ... be a compensatory mechanism to provide sufficient insulin to the peripheral tissues to aid in appropriate and similar glucose ... in adults that hepatic glucose production is more sensitive to insulin than is glucose utilization by the peripheral tissues ( ...
http://care.diabetesjournals.org/content/41/8/1696
*  Plus it
Pioglitazone improves endothelial and adipose tissue dysfunction in pre-diabetic CAD subjects. Atherosclerosis 2011;215:180-183 ... Unfortunately, we did not sample adipose tissue biopsy specimens during the study; therefore, we are unable to determine ... and adipose tissue.. In agreement with previous clinical (20) and animal studies, there is no evidence of PPARγ activity of ... and adipose tissue) and β-cell dysfunction (1,2). The relative contribution of these two defects to the pathogenesis of ...
http://care.diabetesjournals.org/content/36/10/2923
*  Plus it
Comparison of visceral adipose tissue mass in adults African Americans and Whites. Obes Res 2005; 13: 66- 74. ... Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress ... Computed tomography and other imaging techniques allow for direct quantification of visceral adipose tissue (VAT) and ... Abdominal visceral and subcutaneous adipose tissue compartments: Association with metabolic risk factors in the Framingham ...
http://care.diabetesjournals.org/content/32/5/956