These fibrocytes differentiate into myofibroblasts or adipocytes.. Immunoglobulins against insulin-like growth factor 1 (IGF-1 ...
adipocyte-derived leucine aminopeptidase. *ALAP. *aminopeptidase PILS. *aminopeptidase regulator of TNFR1 shedding ...
Absence of an adipogenic effect of rosiglitazone on mature 3T3-L1 adipocytes: increase of lipid catabolism and reduction of ... RESULTS: Rosiglitazone does not induce an increase, but rather a decrease in the lipid content of mature adipocytes. Analysis ... Absence of an adipogenic effect of rosiglitazone on mature 3T3-L1 adipocytes: increase of lipid catabolism and reduction of ... RESULTS: Rosiglitazone does not induce an increase, but rather a decrease in the lipid content of mature adipocytes. Analysis ...
Here the release of EMVs from large (but not small) primary and differentiated and human rat adipocytes in response to ... Thus the EMV-mediated transfer of lipogenic and anti-lipolytic information between large and small adipocytes in response to ... Previously the upregulation of esterification and downregulation of lipolysis in small rat adipocytes upon incubation with ... primary and differentiated rat and human adipocytes. In contrast, the simultaneous presence of tPCPA and BIX-01294 had almost ...
... stem cells gene signature in high-risk myeloma bone marrow linked to suppression of distinct IGFBP2-expressing small adipocytes ... stem cells gene signature in high-risk myeloma bone marrow linked to suppression of distinct IGFBP2-expressing small adipocytes ...
Here, we discover in adipocytes that the outer mitochondrial membrane protein MIGA2 links mitochondria to LDs. We identify an ... We find that in adipocytes MIGA2 is involved in promoting triglyceride (TAG) synthesis from non-lipid precursors. Our data ... transcriptomics of adipocyte differentiation, 3T3 Cells, Adipocytes, Animals, COS Cells, Cell Differentiation, Chlorocebus ... MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes. ...
Rat MAT adipocytes from distal sites have an increased proportion of monounsaturated fatty acids and expression of Scd1/Scd2, ... Rat MAT adipocytes from distal sites have an increased proportion of monounsaturated fatty acids and expression of Scd1/Scd2, ... Rat MAT adipocytes from distal sites have an increased proportion of monounsaturated fatty acids and expression of Scd1/Scd2, ... Rat MAT adipocytes from distal sites have an increased proportion of monounsaturated fatty acids and expression of Scd1/Scd2, ...
Nicotinamide-riboside shifts the differentiation of human primary white adipocytes to beige adipocytes impacting substrate ... Nicotinamide-riboside shifts the differentiation of human primary white adipocytes to beige adipocytes impacting substrate ...
Regulation of glucose and lipid homeostasis by adiponectin: Effects on hepatocytes, pancreatic β cells and adipocytes. ... pancreatic β cells and adipocytes. Together they form a unique fingerprint. ...
Okuyama H, Kurata S, Homma KI, Natori S. Selective inactivation of elongation factor-2 (EF-2) in free adipocytes obtained by ... Okuyama, H, Kurata, S, Homma, KI & Natori, S 1998, Selective inactivation of elongation factor-2 (EF-2) in free adipocytes ... Dive into the research topics of Selective inactivation of elongation factor-2 (EF-2) in free adipocytes obtained by treating ... The molecular mechanism(s) involved in the selective cessation of protein synthesis in free adipocytes obtained by treating fat ...
Insulin stimulates GLUT4 (blood sugar transporter 4) translocation in adipocytes and. * Post author By colinsbraincancer ... 8] where Rab10 was found at GSVs purified from 3T3-L1 adipocytes with anti-GLUT4 antibody. In combination with previous ... Insulin stimulates GLUT4 (blood sugar transporter 4) translocation in adipocytes and muscle tissues. translocation through ... 8 9 the model centring AS160 and Rab10 in GLUT4 translocation in adipocytes is definitely strongly favoured Nutlin 3a although ...
Ot reproduce this inverse correlation between Sirt1 and PTP1B in adipocytes.23 This discrepancy might be because of variations ... Ot reproduce this inverse correlation between Sirt1 and PTP1B in adipocytes.23 This discrepancy might be because of variations ... Uncategorized , Ot reproduce this inverse correlation between Sirt1 and PTP1B in adipocytes.23 This discrepancy might be ... Ot reproduce this inverse correlation between Sirt1 and PTP1B in adipocytes.23 This discrepancy might be ...
Here we showed that obesity-related adipocyte degeneration causes release of cell-free DNA (cfDNA), which promotes macrophage ... Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance ... cfDNA released from degenerated adipocytes promoted monocyte chemoattractant protein-1 (MCP-1) expression in wild-type ... Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance ...
... on adipocyte differentiation and PPARgamma activation. In 3T3-L1 cells, daidzein enhanced adipocyte differentiation and ... Daidzein and the daidzein metabolite, equol, enhance adipocyte differentiation and PPARgamma transcriptional activity.. Title. ... 3T3-L1 Cells, Adipocytes, Animals, Cell Differentiation, Deoxyglucose, Equol, Fatty Acid-Binding Proteins, Glucose, Glucose ... In C3H10T1/2 cells, both daidzein and equol at 1 micromol/L and higher significantly increased adipocyte differentiation and ...
MiR-126-3p and MiR-199a-3p Promote Lipid Accumulation in 3T3-L1 Adipocytes via Regulating HIF-1α and C/EBPα Expression 1.23 MB ... MiR-126-3p and MiR-199a-3p Promote Lipid Accumulation in 3T3-L1 Adipocytes via Regulating HIF-1α and C/EBPα Expression ... In this study, we investigated the role of miR-126-3p and miR-199a-3p on lipid accumulation in 3T3-L1 adipocytes. Transfection ... MiR-126-3p and MiR-199a-3p Promote Lipid Accumulation in 3T3-L1 Adipocytes via Regulating HIF-1α and C/EBPα Expression ...
TRAIL (TNF-related apoptosis-inducing ligand) inhibits human adipocyte differentiation via caspase-mediated downregulation of ...
To do so we took advantage of the fact that in mice BM of lumbar vertebrae (LV) contains few adipocytes whereas BM of caudal ... The adipocyte-derived hormone adiponectin promotes metabolic and cardiovascular health. Inhibiting MAT formation also alters ... The adipocyte-derived hormone adiponectin promotes metabolic and cardiovascular health. Inhibiting MAT. ... The adipocyte-derived hormone adiponectin promotes metabolic and cardiovascular health. Inhibiting MAT. ...
Therefore, the culture of human adipocytes provides a model system for the study of adipocyte derived EVs. Here, we provide a ... Adipocyte-derived EVs are elevated in the peripheral blood and show alterations in their cargo (RNA and protein) during ... Adipocyte-derived EVs can regulate the cellular status of neighboring vascular cells, such as endothelial cells and adipose ... Investigating alterations in adipocyte-derived EVs in vivo is complex because EVs derived from peripheral blood are highly ...
Infusion of insulin impairs human adipocyte glucose metabolism in vitro without decreasing adipocyte insulin receptor binding. ... Infusion of insulin impairs human adipocyte glucose metabolism in vitro without decreasing adipocyte insulin receptor binding. ... Infusion of insulin impairs human adipocyte glucose metabolism in vitro without decreasing adipocyte insulin receptor binding. ... title = "Infusion of insulin impairs human adipocyte glucose metabolism in vitro without decreasing adipocyte insulin receptor ...
... ... A role for PFKFB3/iPFK2 in metformin suppression of adipocyte inflammatory responses. Academic Article * ... Adipocytes were differentiated from 3T3-L1 cells and treated with metformin at various doses and for different time periods. ... Also, metformin increases adipocyte expression of PFKFB3/iPFK2, which is involved in the anti-inflammatory effect of metformin ...
Triple negative breast cancer (TNBC) is an aggressive cancer for which prognosis remains poor. Combination therapy is a promising strategy for enhancing treatment efficacy. Blockade of STAT3 signaling may enhance the response of cancer cells to conventional chemotherapeutic agents. Here we used a SHP-1 agonist SC-43 to dephosphorylate STAT3 thereby suppressing oncogenic STAT3 signaling and tested it in combination with docetaxel in TNBC cells. We first analyzed messenger RNA (mRNA) expression of SHP-1 gene (PTPN6) in a public TNBC dataset (TCGA) and found that higher SHP-1 mRNA expression is associated with better overall survival in TNBC patients. Sequential combination of docetaxel and SC-43 in vitro showed enhanced anti-proliferation and apoptosis associated with decreased p-STAT3 and decreased STAT3-downstream effector cyclin D1 in the TNBC cell lines MDA-MB-231, MDA-MB-468, and HCC-1937. Ectopic expression of STAT3 reduced the increased cytotoxicity induced by the combination therapy. In ...
ADIG/SMAF1 is an adipocyte-specific protein that plays a role in adipocyte differentiation (Kim et al., 2005 [PubMed 15567149 ... Up-regulation of adipogenin, an adipocyte plasma transmembrane protein, during adipogenesis. Hong YH, et al. Mol Cell Biochem, ... Studies in mouse indicate the 80 aa SMAF1 protein is involved in adipocyte tissue function or regulation. Title: Cloning, ...
Particularly, most male obese adolescents (76.9%, P=0.031) had a large (≥33 μM) adipocyte size, small (,80) adipocyte number ( ... intensity with high AIM adipocyte intensity suggesting an anti-inflammatory role of AIM in the adipocytes in male adolescents ... Also, males with adipocyte size ,33 μM had lower serum AIM levels compared to those with ≥33 μM (3.23±1.27 vs 4.27±1.31, P= ... Apoptosis Inhibitor of Macrophages: an Anti-Inflammatory Adipocyte Factor in Mild Adolescent Obesity?. Alexia Karvela a , ...
The winged helix transcription factor Foxa3 regulates adipocyte differentiation and depot-selective fat tissue expansion. * ... Differential adipogenic and inflammatory properties of small adipocytes in Zucker Obese and Lean rats. *Article ...
Are subcutaneous and fat-pad adipocytes depleted, or dead? "If theres apoptosis of the adipocytes, or if the fat cells are ... Adipocytes in Lipoatrophy: Depleted or Dead?. Is lipoatrophy permanent? This, Dr. Roth explains, is an extremely important ... The hypodermis, or subcutis, contains the adipocytes that help to give the dermis shape and thickness, along with larger blood ... Some facial fillers involve injections into the subcutis to fill the space once held by adipocytes. Because these layers are ...
Mature adipocytes are present throughout. Note the infiltration of the fascial plane by well-differentiated adipocytes. The ... Mature adipocytes are present throughout. Note the infiltration of the fascial plane by well-differentiated adipocytes. The ... Lipomas are common benign neoplasms originating from subcutaneous tissue adipocytes, with no tendency to metastasize.[1] [2] ... although they preserve the normal morphology of adipocytes and very rarely metastasize, their behaviour is more locally ...
Adipocytes, muscle cells, endothelial cells. *Tunable cytokine/interleukin expression for immune cell modulation in cancer ...
Background Ganglioside GM3 mediates adipocyte insulin level of resistance, but the part of GM3 in diabetic wound recovery, a ... Background Ganglioside GM3 mediates adipocyte insulin level of resistance, but the. posted by: admin ...
Indra MR, Riawan W. The effect of four weeks restricted diet on serum soluble leptin receptor levels and adipocyte leptin ... The effect of four weeks restricted diet on serum soluble leptin receptor levels and adipocyte leptin receptor density in ... Diet of 40 % normal daily calorie for 4 weeks decreased soluble leptin receptor level, but increased adipocyte leptin receptor ...