Association between asthma and serum adiponectin concentration in women | Thorax
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 2005;46: ... During 1985 and 1986 CARDIA recruited 5115 black and white men and women aged 18-30 years from four clinical centres in ... Effects of adipocyte-derived cytokines on endothelial functions: implication of vascular disease. J Surg Res 2005;126:121-9. ... Although central (visceral) adipocytes are the most important source of adiponectin,11 the serum adiponectin concentration does ...http://thorax.bmj.com/content/63/10/877
C/EBPα Regulates Human Adiponectin Gene Transcription Through an Intronic Enhancer | Diabetes
During adipocyte differentiation, C/EBPβ and C/EBPδ increase transiently at the onset of adipocyte differentiation and decrease ... Serum protein and mRNA profiles of adiponectin in white adipose tissue from wild-type, db/db, and C/EBPβ−/− mice. A: Serum ... Similar to the results from Chub-S7 adipocytes, overexpression or knocking down of C/EBPα in 3T3-L1CARΔ1 adipocytes resulted in ... C and D: Effects of C/EBPα on adiponectin mRNA levels in Chub-S7 (C) or 3T3-L1CARΔ1 (D) adipocytes. C/EBPα, C/EBPβ, PPARγ2 or C ...http://diabetes.diabetesjournals.org/content/54/6/1744.full
Natriuretic peptides enhance the production of adiponectin in human adipocytes and in patients with chronic heart failure. J Am ... White HD, *Platelet Receptor Inhibition in Ischemic Syndrome Management (PRISM) Investigators. . N-terminal pro-B-type ... Atrial natriuretic peptide regulates lipid mobilization and oxygen consumption in human adipocytes by activating AMPK. Biochem ... Treatment of insulin-resistant human adipocytes with NP restored mitochondrial gene expression, suggesting that raising NPs may ...http://care.diabetesjournals.org/content/37/11/3003
Vagal Hyperactivity Due to Ventromedial Hypothalamic Lesions Increases Adiponectin Production and Release | Diabetes
Morphological changes in adipocytes at 1 week after VMH-lesioning are shown in Fig. 1. The distributions of adipocyte sizes ... Sensory and sympathetic nervous system control of white adipose tissue lipolysis. Mol Cell Endocrinol 2010;318:34-43pmid: ... For the histogram of the adipocyte distribution, the adipocyte diameter was represented as a dummy variable for each 10 µm, and ... and adiponectin production and release occur specifically in maturing adipocytes (9). Thus, adipocyte size or fat mass has a ...http://diabetes.diabetesjournals.org/content/63/5/1637.full
The secretome of brown adipose tissue
... and primary brown adipocytes compared to primary white adipocytes. In vivo studies were performed to evaluate physiological ... Hoxc8 for the brite and white in contrast to the brown, and Tcf21 for the white depots. The significance of these gene ... To identify brown adipocyte secreted proteins a signal-sequence trap method was used. All genes identified were cloned and ... nonrecruited molecular signatures of brown, "brite," and white adipose tissues. Open this publication in new window or tab ,, ...http://su.diva-portal.org/smash/record.jsf?pid=diva2:714076
Tbx15 Defines a Glycolytic Subpopulation and White Adipocyte Heterogeneity | Diabetes
Thus, Tbx15 differentially regulates metabolism in white adipocytes and leads to a functional heterogeneity in white fat cells ... Tbx15 Defines a Glycolytic Subpopulation and White Adipocyte Heterogeneity. Kevin Y. Lee, Rita Sharma, Grant Gase, Siegfried ... Tbx15 Defines a Glycolytic Subpopulation and White Adipocyte Heterogeneity. Kevin Y. Lee, Rita Sharma, Grant Gase, Siegfried ... Intrinsic differences in adipocyte precursor cells from different white fat depots. Diabetes 2012;61:1691-1699pmid:22596050. ...http://diabetes.diabetesjournals.org/content/66/11/2822
Serotonin prevents differentiation into brown adipocytes and induces transdifferentiation into white adipocytes
... ... Differentiated HIB1B brown adipocytes treated with serotonin had reduced levels of the thermogenic markers uncoupling protein 1 ... It has recently been shown that serotonin leads to fat accumulation in white adipose tissue (WAT). However, the direct effect ... In parallel, serotonin led to 3-6-fold reduction in the gene expression of brown adipocyte differentiation markers, that is, ...https://insights.ovid.com/pubmed?PMID=29081505
Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase...
White adipocytes store energy (e.g., triglycerides), whereas brown adipocytes consume energy (5,6). Many studies have shown ... A: Expression of brown/beige adipocyte marker, betatrophin, and white adipocyte marker (aP2 and adipoq) genes were measured by ... Irisin stimulates adipocyte browning via p38/ERK pathways. Primary rat adipocytes and 3T3-L1-derived adipocytes were treated ... To investigate the browning effect of r-irisin on adipocytes, we used both 3T3-L1-derived adipocytes and primary rat adipocytes ...http://diabetes.diabetesjournals.org/content/63/2/514.full
Effects of selected bioactive food compounds on human white adipocyte function | Nutrition & Metabolism | Full Text
Cell cultures of primary human adipocytes. Primary human pre-adipocytes for in vitro differentiation from 22 female subjects ... No effects of bioactives on adipocyte differentiation. To measure possible effect of bioactives on adipocyte differentiation ... Adipocyte. 2014;4:1-8.Google Scholar. *. Hong YH, Nishimura Y, Hishikawa D, Tsuzuki H, Miyahara H, Gotoh C, et al. Acetate and ... we investigated their role on human white adipocyte function. ... Role of the adipocyte, free fatty acids, and ectopic fat in ...https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-016-0064-3
Extracellular ATP activates store-operated Ca2+ entry in white adipocytes: functional evidence for STIM1 and ORAI1 |...
white adipocyte. Introduction. White adipose tissue (WAT) is an organ distributed at several locations in the body and with an ... The white adipocyte is now known to be an endocrine cell  and adipocyte secretory hormone-containing vesicles can be ... including white adipocytes [15,16,41]. The ATP-induced elevation of adipocyte [Ca2+]i has been shown to involve activation of ... 2014) Etiology of the membrane potential of rat white fat adipocytes. Am. J. Physiol. Endocrinol. Metab. 307, E161-E175 doi: ...http://www.biochemj.org/content/475/3/691
FTIR imaging of structural changes in visceral and subcutaneous adiposity and brown to white adipocyte transdifferentiation -...
... visceral and subcutaneous adipose tissues in terms of macromolecular content and investigate transdifferentiation between white ... FTIR imaging of structural changes in visceral and subcutaneous adiposity and brown to white adipocyte transdifferentiation ... FTIR imaging of structural changes in visceral and subcutaneous adiposity and brown to white adipocyte transdifferentiation F. ... with a decrease of UCP1 protein content which might be due to the transdifferentiation of brown adipocytes to white adipocytes ...https://pubs.rsc.org/en/content/articlelanding/2015/an/c4an02008a
Adipocytes, White - Semantic Scholar
Adipocytes, White. Known as: White Fat Cell, White adipose cell, Adipocyte, White (More). ... Attainment of a brown adipocyte cell phenotype in white adipocytes, with their abundant mitochondria and increased energy… ( ... Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ. *Frédéric Picard, Martin V. Kurtev, +6 authors ... Acquirement of brown fat cell features by human white adipocytes.. *Claire Tiraby, Geneviève Tavernier, +4 authors Dominique ...https://www.semanticscholar.org/topic/Adipocytes%2C-White/281727
Abstract 52: Capsaicin Activates the Trpv1-camkii-ampk-sirt-1-dependent Mechanism to Trigger Brown Remodeling of White...
Capsaicin Activates the Trpv1-camkii-ampk-sirt-1-dependent Mechanism to Trigger Brown Remodeling of White Adipocytes to ... Capsaicin Activates the Trpv1-camkii-ampk-sirt-1-dependent Mechanism to Trigger Brown Remodeling of White Adipocytes to ... Capsaicin Activates the Trpv1-camkii-ampk-sirt-1-dependent Mechanism to Trigger Brown Remodeling of White Adipocytes to ... Capsaicin Activates the Trpv1-camkii-ampk-sirt-1-dependent Mechanism to Trigger Brown Remodeling of White Adipocytes to ...http://atvb.ahajournals.org/content/35/Suppl_1/A52
Inhibitory Effects of Toll-Like Receptor 4, NLRP3 Inflammasome, and Interleukin-1β on White Adipocyte Browning | Springer for...
... on white adipocyte browning. We report that TLR4 activation by lipopolysaccharide repressed white adipocyte browning in ... Mitochondria in white, brown, and beige adipocytes. Stem cells International 2016: 6067349.CrossRefPubMedCentralPubMedGoogle ... Intrinsic properties of brown and white adipocytes have differential effects on macrophage inflammatory responses. Mediators of ... Inhibitory Effects of Toll-Like Receptor 4, NLRP3 Inflammasome, and Interleukin-1β on White Adipocyte Browning. ...https://rd.springer.com/article/10.1007/s10753-017-0718-y
Frontiers | TGF-β/Smad3 Signaling Regulates Brown Adipocyte Induction in White Adipose Tissue | Endocrinology
Here we review the data supporting this phenomenon and put into perspective the promise of conversion of white fat to a brown ... Here we review the data supporting this phenomenon and put into perspective the promise of conversion of white fat to a brown ... role played by the TGF-beta/Smad3 signaling pathway in modulating the appearance of brown adipocytes in traditional white fat, ... role played by the TGF-beta/Smad3 signaling pathway in modulating the appearance of brown adipocytes in traditional white fat, ...https://www.frontiersin.org/articles/10.3389/fendo.2012.00035/full
Frontiers | Oxygen Deprivation and the Cellular Response to Hypoxia in Adipocytes - Perspectives on White and Brown Adipose...
We suggest that obesity-linked hypoxia may lead to similar alterations in brown adipocytes as in white fat cells - particularly ... We suggest that obesity-linked hypoxia may lead to similar alterations in brown adipocytes as in white fat cells - particularly ... and this leads to substantial changes in white adipocyte function. These changes include increased production of inflammation- ... and this leads to substantial changes in white adipocyte function. These changes include increased production of inflammation- ...https://www.frontiersin.org/articles/10.3389/fendo.2015.00019/full
Enhancing Energy Expending Adipocytes in White Adipose Tissue - Stephen Farmer
... within white adipose (WAT) adipocytes. There are two major types of adipose, white that stores TGs and brown (BAT) that ... Enhancing Energy Expending Adipocytes in White Adipose Tissue Farmer, Stephen Robert Boston University, Boston, MA, United ... Enhancing Energy Expending Adipocytes in White Adipose Tissue. Farmer, Stephen Robert / Boston University. $497,778. ... Enhancing Energy Expending Adipocytes in White Adipose Tissue. Farmer, Stephen Robert / Boston University. $434,920. ...http://grantome.com/grant/NIH/R01-DK098830-02S1
The origin and definition of brite versus white and classical brown adipocytes - Research Collection
The origin and definition of brite versus white and classical brown adipocytes. * Mendeley ... Brown adipose tissue; Brown fat; Brite adipocyte; Beige adipocyte; Non-shivering thermogenesis; Bi-directional interconversion ...https://www.research-collection.ethz.ch/handle/20.500.11850/99732
Angiotensin type 2 receptor activation promotes browning of white adipose tissue and brown adipogenesis | Signal Transduction...
AT2R expression in white adipocyte is upregulated by thyroid hormone T3. Human white adipocytes (day 14) were treated without ... pathway in white adipocytes.. Figure 3. Signaling pathways underlying the AngII-AT2R-induced browning of white adipocytes. (a-c ... adipocyte protein 2 (aP2)). To quantify the number of white adipocytes with multilocular appearance (adipocytes with the ... AT2R activation increases UCP1 and CITED1 expressions in white adipocytes. (a and b) Mouse white adipose cells (day 4) were ...https://www.nature.com/articles/sigtrans201722?error=cookies_not_supported&code=e9eb300c-2774-48c4-92a8-0f416b0c1191
Healthier White Adipose by Recruitment of Beige/Brite Adipocytes - Stephen Farmer
... within white adipose (WAT) adipocytes. There are two major types of adipose, white that stores TGs and brown (BAT) that ... Healthier White Adipose by Recruitment of Beige/Brite Adipocytes Farmer, Stephen Robert Boston University, Boston, MA, United ... Healthier White Adipose by Recruitment of Beige/Brite Adipocytes. Farmer, Stephen Robert / Boston University. $327,810. ... Healthier White Adipose by Recruitment of Beige/Brite Adipocytes. Farmer, Stephen Robert / Boston University. ...http://grantome.com/grant/NIH/R01-DK102199-01
2G). Immunohistochemistry showed that the FLAGΔ256 was mainly expressed in the nucleus of white adipocytes (Fig. 2H). Body ... Overexpression of the mutant FoxO1 in WAT affects size and gene expression of white adipocytes.. To investigate the mechanism ... Adipocyte Liver Kinase b1 Suppresses Beige Adipocyte Renaissance Through Class IIa Histone Deacetylase 4 ... Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J ...http://diabetes.diabetesjournals.org/content/57/3/563
Adipose tissue - Wikipedia
Rosenwald M, Perdikari A, Rülicke T, Wolfrum C (June 2013). "Bi-directional interconversion of brite and white adipocytes". ... Pre-adipocytes are undifferentiated fibroblasts that can be stimulated to form adipocytes. Recent studies shed light into ... "EBF2 promotes the recruitment of beige adipocytes in white adipose tissue". Molecular Metabolism. 5 (1): 57-65. doi:10.1016/j. ... a review on regulators controlling the browning of white adipocytes". Bioscience Reports. 33 (5): 711-19. doi:10.1042/ ...https://en.wikipedia.org/wiki/Adipose
RecName: Full=CCAAT/enhancer-binding protein delta; Short=C/EBP delta; - Protein - NCBI
Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation ... Adipogenesis is the process of cell differentiation by which preadipocytes become adipocytes. During this process the ...https://www.ncbi.nlm.nih.gov/protein/P49716
International Journal of Obesity
Serotonin prevents differentiation into brown adipocytes and induces transdifferentiation into white adipocytes. S Rozenblit- ... No evidence of white adipocyte browning after endurance exercise training in obese men. T Tsiloulis, A L Carey, J Bayliss, B ... S E Benjamin Neelon, A J White, A C Vidal, J M Schildkraut, A P Murtha et al. ... Protective effect of black relative to white race against non-alcoholic fatty liver disease in patients with severe obesity, ...http://links.ealert.nature.com/servlet/MailView?ms=NTY2NjIxMDQS1&r=ODkwMTM2NjI5OAS2&j=MTQwMzI1NzcxNQS2&mt=1&rt=0
Protein must exist in specific brain cells to prevent diet-induced obesity, UT Southwestern researchers find - Healthcanal.com ...
White adipocytes primarily store fat.. "When SIRT1 is present in POMC neurons, the neurons properly convey a signal from leptin ... In addition, the researchers found that SIRT1 must be present in POMC neurons for leptin to stimulate the remodeling of white ... "The drawback to harnessing adrenergic receptors to make more brown adipocytes, as a lot of people are thinking about doing, is ... and that could trigger the remodeling of white fat into brown fat - has high potential. ...https://www.healthcanal.com/brain-nerves/9154-protein-must-exist-in-specific-brain-cells-to-prevent-diet-induced-obesity-ut-southwestern-researchers-find.html