Find Research outputs - University of Huddersfield Research Portal
Familial Adenomatous Polyposis - Symptoms, Causes, Treatment | NORD
Learn about Familial Adenomatous Polyposis, including symptoms, causes, and treatments. If you or a loved one is affected by ... adenomatous polyposis of the colon (APC). *familial multiple polyposis. *FAP. *hereditary polyposis coli ... Mutations in the APC gene cause a group of polyposis conditions that have overlapping features: familial adenomatous polyposis ... Familial adenomatous polyposis is caused by germline (present in the first cell of the embryo) mutations in the APC gene and is ...
MicroRNAs in Invasion and Metastasis in Lung Cancer | IntechOpen
Early-onset colorectal cancer: Current insights and future directions
... such as Lynch syndrome or adenomatous polyposis coli (APC), are at a particularly high risk and require an onset of colonoscopy ... Update on genetic predisposition to colorectal cancer and polyposis. Mol Aspects Med. 2019;69:10-26. [PubMed] [DOI] [Cited in ... and Escherichia coli, have been discovered to have a role in colon carcinogenesis. These pathogens can promote gut inflammation ... Endoscopic management of polyposis syndromes: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy. 2019; ...
Tung-Jui Trieu - Student theses - King's College London
... mechanisms of Wnt-mediated asymmetric stem cell division and the subcellular localisation of Adenomatous Polyposis Coli (APC). ...
H's Brother | Crohn's Disease Forum
Familial polyposis coli, Adenomatous polyposis coli gene mutation ... Familial adenomatous polyposis. This rare, inherited syndrome causes certain cells on the stomachs inner lining to a specific ... Familial adenomatous polyposis can also cause adenomas.. Regular use of certain stomach medications. Fundic gland polyps are ... In the past, these polyps were sometimes associated with familial adenomatous polyposis. In recent years, it has become evident ...
Combinatorial cell-specific regulation of GSK3 directs cell differentiation and polarity in Dictyostelium | Development | The...
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity ...
Inhibitors of beta-Catenin Signaling
The value of trefoil factor 3 expression in predicting the long‑term outcome and early recurrence of colorectal cancer
Wnt and Rho GTPase signaling play critical tasks in governing several - Stem cell application on skin cancer research
... axin and adenomatous polyposis coli tumor suppressor proteins (APC). When Wnt ligands bind with their cognate cell membrane ... the adenomatous polyposis coli tumor suppressor proteins (APC) and glycogen synthase kinase 3 (GSK3) [16]. Nevertheless, when ...
Recombinant Human Wnt-3a Protein (5036-WN): Novus Biologicals
Reactome | APC R564* [cytosol]
AP4 suppresses DNA damage, chromosomal instability and senescence via inducing MDC1/Mediator of DNA damage Checkpoint 1 and...
Adenomatous polyposis coli CCLE:. Cancer Cell Line Encyclopedia. CIN:. Chromosomal instability. CMS:. consensus molecular ... familial adenomatous polyposis (FAP) [26]. ApcMin/+ mice harbor an inactivating mutation in one Apc allele. Upon spontaneous ... Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells. Nat ... coli, which contribute to transformation of colon epithelial cells [46]. ...
HGUE-C-1 is an atypical and novel colon carcinoma cell line | BMC Cancer | Full Text
However, these cells showed loss of heterozygosity affecting Adenomatous Polyposis Coli and nuclear staining of β-catenin ... However, these cells showed loss of heterozygosity affecting Adenomatous Polyposis Coli and nuclear staining of β-catenin ... with the dinucleotide polymorphic repeat marker D5S346 showed loss of heterozygosity affecting the Adenomatous Polyposis Coli ( ...
HuGE Navigator|Genopedia|PHGKB
Role of Chemotherapy and Mechanisms of Resistance to Chemotherapy in Metastatic Castration-Resistant Prostate Cancer - Oncology...
Asha S. Multani | MD Anderson Cancer Center
... senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule ...
Hubrecht Institute - Onderzoeksoutput - Koninklijke Nederlandse Akademie van Wetenschappen (KNAW)
Adenomatous Polyposis Coli 89% * beta Catenin 73% * Neoplasms 23% * Recurrence 11% 104 Citaten (Scopus) ...
KRAS Mutation-Responsive miR-139-5p inhibits Colorectal Cancer Progression and is repressed by Wnt Signaling
... adenomatous polyposis coli; ChIP: chromatin immunoprecipitation; ISH: in situ hybridization; IHC: immunohistochemistry; TUNEL: ... MiR-155 is downregulated in familial adenomatous polyposis and modulates WNT signaling by targeting AXIN1 and TCF4. Mol Cancer ...
Gregory Vlacich - Fingerprint - Research Profiles at Washington University School of Medicine
Neuropilin-1 promotes mitochondrial structural repair and functional recovery in rats with cerebral ischemia | Journal of...
Familial Adenomatous Polyposis: Background, Pathophysiology, Epidemiology
... is the most common adenomatous polyposis syndrome. It is an autosomal dominant inherited disorder characterized by the early ... onset of hundreds to thousands of adenomatous polyps throughout the colon. ... and attenuated adenomatous polyposis coli (AAPC). Gardner syndrome is characterized by colonic polyposis typical of FAP, along ... Familial adenomatous polyposis (FAP) is the most common adenomatous polyposis syndrome. It is an autosomal dominant inherited ...
APC related Antibodies, Proteins, cDNA and ELISA Kits- Cusabio
Recombinant Rat Adenomatous polyposis coli protein (Apc), partial. Yeast. E.coli. Baculovirus. Mammalian cell. In Vivo ... Adenomatous polyposis coli protein is a protein in humans that is encoded by APC gene. Tumor suppressor. Promotes rapid ... Recombinant Human Adenomatous polyposis coli protein (APC), partial. Yeast. Baculovirus. Mammalian cell. In Vivo Biotinylation ... Recombinant Mouse Adenomatous polyposis coli protein (Apc), partial. Yeast. Baculovirus. Mammalian cell. In Vivo Biotinylation ...
Selection of disease-causing mutations, in a standard table of the genetic code of amino acids - DocCheck
Gardner Syndrome | Profiles RNS
A variant of ADENOMATOUS POLYPOSIS COLI caused by mutation in the APC gene (GENES, APC) on CHROMOSOME 5. It is characterized by ... not only the presence of multiple colonic polyposis but also extracolonic ADENOMATOUS POLYPS in the UPPER GASTROINTESTINAL ... Adenomatous Polyps [C04.557.470.035.215]. *Adenomatous Polyposis Coli [C04.557.470.035.215.100]. *Gardner Syndrome [C04.557. ... Intestinal Polyposis [C06.405.469.578]. *Adenomatous Polyposis Coli [C06.405.469.578.249]. *Gardner Syndrome [C06.405.469.578. ...
Publications 2007 | FAMRI
Balusu R, Armas ML, Jaiswal AS, Kundu CN, Narayan S. Structural basis of interaction of adenomatous polyposis coli (APC) with ... Kundu CN, Balusu R, Jaiswal AS, Gairola CG, Narayan S. Cigarette smoke condensate-induced level of adenomatous polyposis coli ... Kundu CN, Balusu R, Jaiswal AS, Narayan S. Adenomatous polyposis coli-mediated hypersensitivity of mouse embryonic fibroblast ... Structure/function analysis of the interaction of adenomatous polyposis coli with DNA polymerase beta and its implications for ...
Are Non-dysplastic Crypts with Corrupted Shapes the Initial Recordable Histological Event in the Development of Sporadic...
Adenomatous polyposis coli (APC) and WNT signaling regulator control colonic crypts by adjusting their differentiation via ... The absence of adenomatous tissue in NDCs of the stalk should rule out the possibility that the adenomatous tissue on top had ... Mixed hyperplastic adenomatous polyps/serrated adenomas. A distinct form of colorectal neoplasia. Am J Surg Pathol 14: 524-537 ... Table II shows the number of NDCs below the basal aspect of adenomatous tissue or intercalated with DCs in the 255 conventional ...
Catenins and their associated proteins in colorectal cancer | Histology and Histopathology
Cell Biology - Division R - Research output - University of Texas Southwestern Medical Center
Truncated adenomatous polyposis coli mutation induces Asef-activated Golgi fragmentation. Kim, S. B., Zhang, L., Yoon, J., Lee ... Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer. Zhang, L., Theodoropoulos, P. C., Eskiocak ...
Complications of restorative proctocolectomy with ileal pouch-anal anastomosis<...
Adenomatous Polyposis Coli Medicine & Life Sciences 23% * Anastomotic Leak Medicine & Life Sciences 22% ... the procedure of choice for most patients who require colectomy because of ulcerative colitis or familial adenomatous polyposis ... the procedure of choice for most patients who require colectomy because of ulcerative colitis or familial adenomatous polyposis ... the procedure of choice for most patients who require colectomy because of ulcerative colitis or familial adenomatous polyposis ...