Vesicular transport adaptor protein - Wikipedia
Vesicular transport adaptor proteins are proteins involved in forming complexes that function in the trafficking of molecules ... Epsin and AP180 in the ANTH domain are other adaptor proteins that have been reviewed. An important transport complex, COPII, ... Most of the adaptor proteins are heterotetramers. In the AP complexes, there are two large proteins (∼100 kD) and two smaller ... in the cargo proteins that interact with the adaptor proteins can be very short. For example, one well-know example is the ...https://en.wikipedia.org/wiki/Vesicular_transport_adaptor_protein
Sorting of the v-SNARE VAMP7 in Dictyostelium discoideum: a role for more than one Adaptor Protein (AP) complex.
Soluble N-ethylmaleimide-sensitive-factor Attachment protein Receptors (SNAREs) participate in the specificity of membrane ... 0/Adaptor Protein Complex 2; 0/Adaptor Proteins, Vesicular Transport; 0/Macromolecular Substances; 0/Protozoan Proteins; 0/R- ... Adaptor Protein Complex 2 / metabolism. Adaptor Proteins, Vesicular Transport / metabolism*. Animals. Cell Membrane / ... Protein Transport / physiology. Protozoan Proteins / metabolism. R-SNARE Proteins / metabolism*. Recombinant Fusion Proteins / ...http://www.biomedsearch.com/nih/Sorting-v-SNARE-VAMP7-in/18634783.html
Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG.
0/ATG14 protein, human; 0/Adaptor Proteins, Vesicular Transport; 0/Apoptosis Regulatory Proteins; 0/BECN1 protein, human; 0/ ... Adaptor Proteins, Vesicular Transport / chemistry*. Amino Acid Motifs. Amino Acid Sequence. Apoptosis Regulatory Proteins / ... Membrane Proteins; 0/Tumor Suppressor Proteins; 0/UVRAG protein, human; EC 22.214.171.124/Class III Phosphatidylinositol 3-Kinases ... Protein expression and purification The CC domain of rat Beclin 1 (residues 174-266) was cloned as a His6-tagged protein in a ...http://www.biomedsearch.com/nih/Imperfect-interface-Beclin1-coiled-coil/22314358.html
No difference in B. pseudomallei phagocytosis or killin | Open-i
Adaptor Proteins, Vesicular Transport/genetics/physiology. *Animals. *Cytoprotection/genetics/immunology. *Female. *Liver ... and TIR-domain-containing adaptor protein inducing IFNbeta (TRIF) are regarded as the key signaling adaptor proteins for TLRs. ... and TIR-domain-containing adaptor protein inducing IFNbeta (TRIF) are regarded as the key signaling adaptor proteins for TLRs. ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2566818_pone.0003494.g007&req=4
TRIF−/− mice are more susceptible to vaccinia infec | Open-i
Adaptor Proteins, Vesicular Transport/deficiency/immunology. *Animals. *Cells, Cultured. *Immunity, Innate. *Macrophages/ ... the only known adapter protein for TLR3.We then focused on TLR4, the other Toll-like receptor that signals through TRIF.The ... the only known adapter protein for TLR3.We then focused on TLR4, the other Toll-like receptor that signals through TRIF.The ... the only known adapter protein for TLR3. Unexpectedly, bioluminescence imaging showed that mice lacking TRIF are more ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2529451_ppat.1000153.g001&req=4
ZFIN Publication: Grisham et al., 2013
Adaptor Proteins, Vesicular Transport/chemistry. *Adaptor Proteins, Vesicular Transport/genetics*. *Adaptor Proteins, Vesicular ... Ap1b1 is a subunit of the adaptor complex AP-1, which has been implicated in the targeting of basolateral membrane proteins. In ... we describe auditory/vestibular mutants isolated from forward genetic screens in zebrafish with lesions in the adaptor protein ... we examined the localization of basolateral membrane proteins in hair cells. We observed that the Na+/K+-ATPase pump (NKA) was ...https://zfin.org/ZDB-PUB-130425-2
"Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kap" by Ezra Aksoy, Wim Vanden Berghe et al.
Here, we investigated the consequences of pharmacological inhibition of PI3K on Toll-IL-1 receptor domain-containing adapter- ... Adaptor Proteins, Vesicular Transport; Androstadienes; Chromones; DNA-Binding Proteins; Dendritic Cells; Down-Regulation; ... Here, we investigated the consequences of pharmacological inhibition of PI3K on Toll-IL-1 receptor domain-containing adapter- ...https://escholarship.umassmed.edu/infdis_pp/90/
"Free cholesterol accumulation in macrophage membranes activates Toll-l" by Yu Sun, Minako Ishibashi et al.
... prolonged p38 mitogen-activated protein kinase activation, and induction of Mmps, Ctsk, and S100a8, potentially contributing to ... leading to sustained phosphorylation of p38 mitogen-activated protein kinase and induction of p38 targets, including Ctsk, ... Adaptor Proteins, Vesicular Transport; Animals; Aorta; Apolipoproteins E; Cathepsin K; Cathepsins; Cell Membrane; Cells, ... Proteins; Receptor Activator of Nuclear Factor-kappa B; S100 Proteins; *Signal Transduction; Time Factors; Toll-Like Receptor 3 ...https://escholarship.umassmed.edu/infdis_pp/59/
Vesicular transport protein - Wikipedia
... such as the EHD protein family Rab proteins SNAREs Vesicular transport adaptor proteins e.g. Sorting nexins Synaptotagmin TRAPP ... Membrane transport protein Wikipedia:MeSH_D12.776#MeSH_D12.776.543.990_---_vesicular_transport_proteins Vesicular Transport ... A vesicular transport protein, or vesicular transporter, is a membrane protein that regulates or facilitates the movement of ... retrograde transport ; Golgi ----> Endoplasmic reticulum COP 2 (Cytosolic coat protein complex ) : anterograde transport ; RER ...https://en.wikipedia.org/wiki/Vesicular_transport_protein
Denigma: Mooijaart SP et al., 2004
Keywords: *Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport/*genetics; Adult; Aged; Aged, 80 and ... Shc Signaling Adaptor Proteins; Survival Analysis. Journal: Experimental gerontology. Volume: 39. Issue: 2. Pages: 263-8. Date ...http://denigma.de/datasets/reference/2282
Lafer, E. M.<...
Vesicular Transport Adaptor Proteins Medicine & Life Sciences View full fingerprint Network Recent external collaboration on ... Study Shows Heat Shock Proteins Ram into Other Proteins, Generating Force that is Beneficial. Bruce J Nicholson, Rui J Sousa & ... Membrane fission by protein crowding. Snead, W. T., Hayden, C. C., Gadok, A. K., Zhao, C., Lafer, E. M., Rangamani, P. & ... Microscopic collisions help proteins stay healthy. Bruce J Nicholson, Rui J Sousa & Eileen M Lafer ...https://scholars.uthscsa.edu/en/persons/eileen-m-lafer
Stabilin-1 localizes to endosomes and the trans-Golgi network in human macrophages and interacts with GGA adaptors.
ADP-Ribosylation Factors/immunology/*metabolism, Adaptor Proteins; Vesicular Transport/immunology/*metabolism, Amino Acid ... Protein Binding/physiology, Protein Structure; Tertiary/physiology, Protein Transport/drug effects/immunology, Receptors; ... Stabilin-1 localizes to endosomes and the trans-Golgi network in human macrophages and interacts with GGA adaptors.. ... Motifs/immunology, Antigens; CD/immunology, Brefeldin A/pharmacology, Carrier Proteins/immunology/metabolism, Cell Adhesion ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:96016
SOD2 H. sapiens - Ageing Factor Page - JenAge Ageing Factor Database
MeSH Terms: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport/physiology; Aging/physiology ... Membrane Transport Proteins; Mitochondria/genetics; Mitochondria/metabolism; Mitochondrial Proteins; Muscle, Skeletal/ ... Protein Name. Species. UniProt Accession Number. UniProt Entry Name. Protein Function. Sequence. ... MeSH Terms: Membrane Proteins/genetics; Membrane Proteins/metabolism; Oxidative Stress. *Marzani B, Felzani G, Bellomo RG, ...http://agefactdb.jenage.de/cgi-bin/jaDB.cgi?RKEY=r001&SEARCH=AF_000772&TYPE=d_fa&VIEW=detail
NAVER Academic > Search...
Adaptor Proteins, Vesicular Transport, genetics, physiology, Animals, Echocardiography, Electrocardiography, drug effects, ...https://academic.naver.com/search.naver?field=3&query=ANESTHESIOLOGY+114%EA%B6%8C+3%ED%98%B8
Hgs HGF-regulated tyrosine kinase substrate [Mus musculus (house mouse)] - Gene - NCBI
... a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal ... is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM ... BASP1; Brain acid soluble protein 1 (BASP1 protein). pfam07223. Location:525 → 769. DUF1421; Protein of unknown function ( ... BASP1; Brain acid soluble protein 1 (BASP1 protein). pfam07223. Location:525 → 743. DUF1421; Protein of unknown function ( ...https://www.ncbi.nlm.nih.gov/gene/?term=15239
NAVER Academic > Search...
Adaptor Proteins, Vesicular Transport, chemistry, metabolism, Animals, Biological Transport, physiology, Humans, Membrane ... Diversity in structure and function of tethering complexes: evidence for different mechanisms in vesicular transport regulation ... Animals, Collagen, chemistry, Crystallography, X-Ray, Humans, Models, Molecular, Nucleic Acid Conformation, Peptides, Protein ... Anti-Bacterial Agents, pharmacology, Bacterial Proteins, genetics, DNA Fingerprinting, DNA, Bacterial, chemistry, Drug ...https://academic.naver.com/search.naver?field=3&query=Journal+of+medicinal+food+9%EA%B6%8C+2%ED%98%B8&page=11
Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease. - Department of...
Recent evidence suggests that the FISH adapter protein binds to, and potentially regulates, ADAM12 (a disintegrin and ... ADAM Proteins, ADAM12 Protein, Adaptor Proteins, Vesicular Transport, Age of Onset, Aged, Alleles, Alzheimer Disease, Case- ... Recent evidence suggests that the FISH adapter protein binds to, and potentially regulates, ADAM12 (a disintegrin and ... Control Studies, Female, Genetic Predisposition to Disease, Heterozygote, Humans, Male, Membrane Proteins, Middle Aged, ...https://www.psych.ox.ac.uk/publications/622670
Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through...
... because maturation of pro-IL-1β occurs normally in the absence of the adaptor protein ASC. In contrast, processing of pro-IL-1β ... we found that neither the unfolded protein response transcription factors XBP1 and CHOP nor the TLR4 adaptor molecule MyD88 is ... Instead, both caspase activation and IL-1β production require the alternative TLR4 adaptor TRIF. This pathway may contribute to ... generates perturbations known as ER stress that engage the unfolded protein response. ER stress is involved in many ...https://www.rdm.ox.ac.uk/publications/459612
AP4B1 gene - Genetics Home Reference - NIH
β-COP, a Coat Protein of Nonclathrin-Coated Vesicles of the Golgi Complex, is Involved in Transport of Vesicular Stomatitis...
Pearse BMF, Robinson MS (1990) Clathrin, adaptors, and sorting. Annu Rev Cell Biol 6: 151-171PubMedCrossRefGoogle Scholar ... β-COP, a Coat Protein of Nonclathrin-Coated Vesicles of the Golgi Complex, is Involved in Transport of Vesicular Stomatitis ... 1993) β-COP, a Coat Protein of Nonclathrin-Coated Vesicles of the Golgi Complex, is Involved in Transport of Vesicular ... Coat Protein Golgi Complex Coated Vesicle Vesicular Structure Membrane Traffic These keywords were added by machine and not by ...https://rd.springer.com/chapter/10.1007/978-3-662-02928-2_26
Potential therapeutic targets for atherosclerosis in sphingolipid metabolism | Clinical Science
GluCer is transferred from the cis-Golgi to the trans-Golgi by vesicular transport or a carrier protein, four-phosphate adapter ... vesicular transport and non-vesicle transporters. Apart from CERT for ceramide transport and FAPP2 for GluCer transport, there ... after being transported from the ER by ceramide transfer protein (CERT) in a non-vesicular pathway, ceramide acquires a ... such as protein spinster homolog 2 (SPNS2) for S1P, C1P transfer protein (CPTP) for C1P, and glycolipid transfer protein (GLTP ...http://www.clinsci.org/content/133/6/763
AP4M1 Gene - GeneCards | AP4M1 Protein | AP4M1 Antibody
Protein Coding), Adaptor Related Protein Complex 4 Mu 1 Subunit, including: function, proteins, disorders, pathways, orthologs ... They control the vesicular transport of proteins in different trafficking pathways (PubMed:10436028, PubMed:11139587, PubMed: ... Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in ... Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in ...http://www.genecards.org/cgi-bin/carddisp.pl?gene=AP4M1
The interplay between clathrin-coated vesicles and cell signalling. - Nuffield Department of Surgical Sciences
Protein-lipid and protein-protein interactions control both the targeting of signalling molecules and their binding partners to ... Internalization of cargo proteins and lipids at the cell surface occurs in both a constitutive and signal-regulated manner ... Adaptor Proteins, Vesicular Transport, Animals, Cell Cycle, Clathrin-Coated Vesicles, Coated Pits, Cell-Membrane, Endocytosis, ... Protein-lipid and protein-protein interactions control both the targeting of signalling molecules and their binding partners to ...https://www.nds.ox.ac.uk/publications/817495
Selective use of TRAM in lipopolysaccharide (LPS) and lipoteichoic acid (LTA) induced NF-kappaB activation and cytokine...
We conclude that TRAM is an adaptor protein for both TLR4 and TLR2/6 signaling in SFs, HUVECs, and murine embryonic fibroblasts ... One of these adaptors, Toll-IL-1R domain-containing adaptor inducing IFN-beta-related adaptor molecule (TRAM), has been shown ... TRAM is a suitable candidate to compensate for these adaptors. To investigate a potential role for TRAM in LPS signaling in ... A possible explanation was redundancy of the adaptors during LPS signaling. ...https://www.ndorms.ox.ac.uk/publications/224740
TLR signalling and adapter utilization in primary human in vitro differentiated adipocytes. - Nuffield Department of...
Using siRNA, it was confirmed that LPS-dependent signalling in adipocytes occurs via TLR4 utilizing the adapter molecules MyD88 ... We have explored TLR signalling in primary human in vitro differentiated adipocytes and investigated the specific adapter ... Adipocytes, Humans, Lipopolysaccharides, Adaptor Proteins, Vesicular Transport, Protein Isoforms, RNA, Small Interfering, Poly ... TLR signalling and adapter utilization in primary human in vitro differentiated adipocytes. Share Share Share Share ...https://www.ndorms.ox.ac.uk/publications/339932