Creative BioMart offer AP2A2 proteins for life sciences research. All the products are rigorously tested to meet the most ... AP2A2;adaptor-related protein complex 2, alpha 2 subunit;ADTAB, CLAPA2;AP-2 complex subunit alpha-2;adaptin;alpha B;alpha ... clathrin assembly protein complex 2 alpha-C large chain;plasma membrane adaptor HA2/AP2 adaptin alpha C subunit;clathrin- ... protein binding. PPP2R1A;ENTPD3;PROM1;RAD51C;FGF2;LCMT1;ANKMY2;TTC33;HINFP. protein complex binding. CFLAR;PDX1;TAB1;FLCN;WASF1 ...

Adaptins are clustered subunits of adaptor protein (AP) complexes. There are several types of adaptin, each related to a ... 2011). "The Fifth Adaptor Protein Complex". PLOS Biology. 9 (10): e1001170. doi:10.1371/journal.pbio.1001170. PMC 3191125. PMID ... Clathrin adaptor proteins, also known as adaptins, are proteins that mediate the formation of vesicles for intracellular ... "Bivalent Motif-Ear Interactions Mediate the Association of the Accessory Protein Tepsin with the AP-4 Adaptor Complex". Journal ...

Gamma-adaptin appendage domain from clathrin adaptor AP1, L762E mutant ... ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT: A. SMTL:PDB. SMTL Chain Id:. PDB Chain Id:. A. A ... Gamma-adaptin appendage domain from clathrin adaptor AP1, L762E mutant Coordinates. PDB Format Method. X-RAY DIFFRACTION 1.71 Å ...

clathrin adaptor complexes medium subunit family protein , chr1:22372954-22375550 REVERSE. swissprot. blastx. No significant ... Protein prediction analysis (2) Protein prediction analysis (2) Prediction based on ESTScan [ Show ESTScan Detail] >SGN-P692219 ...

Name: adaptor-related protein complex 2, beta 1 subunit. Synonyms: 1300012O03Rik. Type: Gene ... Name: DLG associated protein 3. Synonyms: PSD-95/SAP90-binding protein 3, SAP90/PSD 95 associated protein 3, DAP3, Sapap3, ... Name: ubiquitin protein ligase E3 component n-recognin 4. Synonyms: A930005E13Rik, LOC381562, D930005K06Rik, 1810009A16Rik, ...

gi,6753072,ref,NP_033808.1, adaptor protein complex AP-1, mu 2 subunit; adaptor-related protein complex AP-1, mu 2 su.... ... gi,1703027,sp,P53676,A3M1_RAT Adapter-related protein complex 3 mu 1 subunit (Mu-adaptin 3A) (AP-3 adapter complex mu.... ... gi,14210504,ref,NP_115882.1, adaptor-related protein complex 1, mu 1 subunit; clathrin assembly protein complex 1, me.... ... gi,6753074,ref,NP_033809.1, adaptor protein complex AP-2, mu1; adaptor-related protein complex AP-2, mu1; clathrin-as.... ...

Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. 0.8810. 29. AP2S1. Adaptor related protein complex 2 subunit sigma ... The Human Protein Atlas project is funded. by the Knut & Alice Wallenberg Foundation. ... DNA polymerase epsilon 4, accessory subunit. 0.9048. 29. GCNT2. Glucosaminyl (N-acetyl) transferase 2 (I blood group). 0.9048. ... General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made ...

adaptor related protein complex 1 subunit gamma 1. involved_in. IDA. IMP. PMID:22539861. SynGO. PMID:22539861 PMID:22539861. ... adaptor related protein complex 1 subunit sigma 2. involved_in. ISO. (MGI:5617942,PMID:20203623). RGD. PMID:20203623. MGI: ... adaptor related protein complex 3 subunit delta 1. involved_in. IDA. IBA. IMP. ISO. PMID:22539861. PMID:21873635. (MGI:6189637, ... Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine ...

G protein-coupled receptors (GPCRs) constitute a family of receptors with seven transmembrane alpha-helical domains (7TM ... Tyrosine-based sorting signal responsible for the interaction with µ2 subunit of AP (Adaptor Protein) complex. plasma membrane, ... Tyrosine-based sorting signal responsible for the interaction with µ2 subunit of AP (Adaptor Protein) complex. plasma membrane, ... Tyrosine-based sorting signal responsible for the interaction with µ2 subunit of AP (Adaptor Protein) complex. plasma membrane, ...

We have shown that cS5 can form a cytoplasmic complex with the p85 subunit of the PI3K and the scaffolding adapter protein Gab2 ... only binds O-GlcNAcylated proteins. In addition, glycosylated proteins present in human CML (Ku812, K562), AML (MV4-11) and ... SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information. Nucleic Acids Res 2014; 42: ... a) Schematic representation of murine STAT5A and the mutant STAT5 proteins. (b) Sequence of the human STAT5A N-terminus from ...

... caused by mutations of the genes encoding proteins ... EDA-A2 binds to XEDAR, which does not require a protein adaptor ... regulatory subunit of the IKK complex; TAK1, TGF-beta activated kinase 1; TAB1, activated kinase 1 binding protein; TAB2, ... It acts as an Edar adaptor molecule linking this receptor to a RING-domain of Traf6 protein (Megas et al. 2011), which strongly ... May P, Woldt E, Matz RL, Boucher P (2007) The LDL receptor-related protein (LRP) family: an old family of proteins with new ...

Hagemann AI, Schindler S, Scholpp S (2010). The clathrin adaptor-protein subunit ap2m1 regulates canonical Wnt signalling in ... the ligand-receptor complex and the transducer complex take separate routes. The Wnt-Fz-Lrp6 complex follows a Rab-positive ... Hagemann AI, Schindler S, Scholpp S (2010). The clathrin adaptor-protein subunit ap2m1 regulates canonical Wnt signalling in ... the ligand-receptor complex and the transducer complex take separate routes. The Wnt-Fz-Lrp6 complex follows a Rab-positive ...

Experiments aimed at mapping UBCv1 inhibitory activity indicated that this viral protein acts upstream or at the level step of ... In this work, we have revealed that early viral protein UBCv1, the only known conjugating enzyme encoded by a virus, modulates ... In resting cells, IκB retains NF-κB complex subunits p65 and p50 in their inactive form in the cell cytosol. Thus, its ... Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7. ...

More recently, mutations of the codon Arg15 (p.R15) in the adaptor-related protein complex 2, σ-2 subunit that interacts with ... Approximately 30% of total plasma magnesium is protein-bound and approximately 70% is filterable through artificial membranes ( ... 15% complexed, 55% free Mg2+ ions). With a glomerular filtration rate (GFR) of approximately 150 L per day and an ...

AP1S1 (Adaptor Related Protein Complex 1 Subunit Sigma 1): MEDNIK syndrome (Mental retardation, enteropathy, deafness, ... Black lines indicate protein-protein interactions. Green dashed lines indicate protein-DNA interactions between TFs and MER41 ... Black lines indicate protein-protein interactions. Dashed green lines indicate protein-DNA interactions between TFs and MER41 ... Protein interactors of these candidate targets were added in order to establish a final list of 80 proteins that are putatively ...

The experimental data is in the form of mass spectrometry, yeast two-hybrid, protein structure prediction, light microscopy and ... The YRC PDR provides for the searching of millions of protein descriptions from many databases to find proteins and public ... experimental data describing those proteins produced by the YRC. ... sigma-adaptin subunit of adaptor protein complex 3 (AP-3) ... Adaptor complexes medium subunit family status:Partially_confirmed UniProt:P90761 protein_id:CAB0279... MS ...

Gene Name: adaptor-related protein complex 2, sigma 1 subunit. MGI ID: MGI:2141861 ...

The APL5 Subunit of the AP3 Adaptor Protein Complex is Required for Cytokinesis Checkpoint Function in Schizosaccharomyces ... Protein Body Biogenesis and Utility in Recombinant Protein Production in Nicotiana benthamiana, Reza Saberianfar ... Polycomb Repressive Complex 2 Regulates miR-200b in Retinal Endothelial Cells: Possible Implications in Diabetic Retinopathy, ... Hydrology and Biogeochemistry of a Bog-Fen-Tributary Complex in the Hudson Bay Lowlands, Ontario, Canada, Thomas A. Ulanowski ...

... adaptor proteins such as the four-subunit complex AP2. Clathrin adaptors in turn bind to the clathrin lattice which is thought ... Vesicle formation at various steps is driven by specific coat protein complexes. The C. elegans genome contains genes encoding ... Clathrin and cargo molecules are assembled into clathrin-coated pits on the plasma membrane together with an adaptor complex ... From the Golgi, secretory proteins and some membrane proteins proceed to either the plasma membrane or to the endosomal system ...

... using SNAP as an adaptor protein) disrupts the SNARE complex after fusion is complete so its subunits can be recycled for ... and then with these tools discovered that the receptors for SNAP in membranes were actually complexes of proteins (which we ... demonstrating that the SNARE complex is not only necessary but is sufficient for fusion. There are many proteins known and ... Using this assay as a guide, we purified as a required factor the NEM-Sensitive Fusion protein (NSF). This led to the ...

... one of the four subunits of the adaptor protein complex-4 (AP-4), identified by chromosomal microarray analysis. ... Adaptor protein complex-4 (AP-4) deficiency causes a novel autosomal recessive cerebral palsy syndrome with microcephaly and ... Adaptor protein complex-4 (AP-4) deficiency causes a novel autosomal recessive cerebral palsy syndrome with microcephaly and ... indicate that disruption of any one of the four subunits of AP-4 causes dysfunction of the entire complex, leading to a ...

... between the channel and contactin is mediated by saturatable adaptor protein or proteins that may include endogenous β subunits ... The immunoprecipitated protein complexes were probed by pan sodium channel antibody (top panel, lane 3) and contactin antibody ... The protein concentration of the supernatants was determined by the Bradford protein assay, and 100 μg of total protein was ... To verify recombinant protein production, 10 μl of the eluted proteins were separated by SDS-PAGE, and the gel was stained with ...

Adaptor Protein Complex mu Subunits [D12.776.543.990.150.500.500] * Adaptor Protein Complex sigma Subunits [D12.776.543.990. ... Adaptor Protein Complex alpha Subunits [D12.776.543.990.150.500.100] * Adaptor Protein Complex beta Subunits [D12.776.543.990. ... Adaptor Protein Complex delta Subunits [D12.776.543.990.150.500.300] * Adaptor Protein Complex gamma Subunits [D12.776.543.990. ... They have been primarily found as components of ADAPTOR PROTEIN COMPLEX 3 and ADAPTOR PROTEIN COMPLEX 4.. Terms. Adaptor ...

Another focus of this study, DDK, is composed of the catalytic subunit Cdc7 and one of two distinct adaptor proteins, Drf1 or ... We characterized Xenopus Claspin as a kinase substrate of DDK which forms a stable nuclear complex with Cdc7 and Drf1 under ... Claspin mutant proteins unable to interact with DDK still bind to Chk1 and rescue Chk1 activation in Claspin-depleted extracts ... Drf1 forms a stable, active complex with Cdc7, even after replication arrest in egg extracts. Accumulation of Drf1 on chromatin ...

... biochemical and cell-based analyses of the heterodecameric core GID/CTLH E3 ligase complex reveal its molecular architecture, ... In brief, the multi-subunit E3 ligase complex is formed around a stable catalytic core formed by the RING proteins MAEA and ... WDR26 does not associate with the core CRL4 subunit Ddb1 in cells relative to the canonical CRL4 substrate adapter protein ... Note that Hbp1 not only binds its corepressor protein Sin3a but also multiple subunits of the GID complex. ...

Gene table of AP1S3 : adaptor related protein complex 1 sigma 3 subunit Gene-disease associations table Disease ID. Disease ... Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters. R-HSA-164938. 8.59. ... Nef mediated downregulation of MHC class I complex cell surface expression. R-HSA-164940. 9.66. ...

The adaptor protein chaperone AAGAB stabilizes AP-4 complex subunits. Mol Biol Cell. 2022;33(12):ar109. ... Bonifacinos group has conducted research on signals and adaptor proteins that mediate protein sorting to endosomes and ... sorting signals and adaptor proteins that select cargo proteins for packaging into the transport carriers, (2) microtubule ... His group discovered new sorting signals and adaptor proteins, and applied this knowledge to the elucidation of the causes of ...

adaptor related protein complex 2 subunit sigma 1. 19. Rare Single Gene Mutation. 1. 3. ... SRP receptor subunit alpha. 11. Rare Single Gene Mutation. 1. 3. STXBP1. Syntaxin binding protein 1. 9. Rare Single Gene ... PHD finger protein 2. 9. Rare Single Gene Mutation. 1. 8. PHF21A. PHD finger protein 21A. 11. Rare Single Gene Mutation, ... KAT8 regulatory NSL complex subunit 1. 17. Rare Single Gene Mutation, Syndromic, Functional. 1. S. 11. ...

Adaptor protein complex AP-2 alpha-2 subunit Locations in the PathwayBrowser Expand all ... Formation of CD4:Nef:AP-2 Complex:v-ATPase Complex (Homo sapiens) * AP-2 Complex [cytosol] (Homo sapiens) * Adaptor protein ... Formation of CD8:Nef:AP-2 Complex:v-ATPase Complex (Homo sapiens) * AP-2 Complex [cytosol] (Homo sapiens) * Adaptor protein ... Recruitment of AP-2 complex and clathrin (Homo sapiens) * AP-2 Complex [cytosol] (Homo sapiens) * Adaptor protein complex 2 (AP ...

adaptor-related protein complex 2, beta 1 subunit. -2.28. -0.99. 1.76. 9815 ... Protein lysates (50 μg) were obtained 96 h after transfection. Proteins were separated by NuPAGE on 4-12% bis-tris gels ( ... The mRNA and protein expression levels of MTDH/MTDH were significantly repressed in miR-miR-145-5p or miR-145-3p transfectants ... B. MTDH protein expression was evaluated by Western blot analyses in SK-MES-1 and EBC-1 72 h after transfection with miR-145-5p ...