Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in...
... and corepressor genes should continue and may serve as a valuable resource for investigations of other hormone-related ... SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [SMARCA4], and member 2 [ ... E1A binding protein p300 [EP300], cyclin D1 [CCND1], non-metastatic cells 1 protein [NME1], nuclear receptor coactivator 1 [ ... protein arginine methyltransferase 1 [PRMT1], peroxisome proliferator-activated receptor binding protein [PPARBP] and CREB ...
Orbital Solitary Fibrous Tumour: A Report of Two Cases and Review of the Literature | SciTechnol
... factor VIII-related antigen), neural (S-100 protein) and smooth muscle-specific actin [46]. ... Case 2. Second case was a 74-year-old patient who came in due to proptosis of the left eye and progressive vertical diplopia ... Figure 2: A) Intraoperative vision of patient 1, superior transpalpebral internal orbitotomy of the left eye showing a well- ... proposed that this marker was a potential tool for the diagnosis of this type of tumour [2]. In addition, SFT is immunoreactive ...
Whole-genome sequencing of patients with rare diseases in a national health system. - MRC Weatherall Institute of Molecular...
The skeletome of the red coral Corallium rubrum indicates an independent evolution of biomineralization process in octocorals |...
Agrin-like glycoproteins and proteins with sugar-binding domains are also predominant. Twenty-seven and 23 proteins were ... We identified a total of 102 OM proteins, 52 are found in the two red coral biominerals with scleritin being the most abundant ... The inferred regulatory function of these OM proteins suggests that the difference between the two biominerals is due to the ... Contrary to reef building corals, the red coral organic matrix possesses a large number of collagen-like proteins. ...
Gene expression profile during proliferation and differentiation of rainbow trout adipocyte precursor cells | BMC Genomics |...
Overall, our study demonstrates the coordinated expression of functionally related genes during proliferation and ... translation and protein folding), cellular remodelling and autophagy. In addition, the implication of the eicosanoid signalling ... and T-cell activation RhoGTPase activating protein (TAGAP). Actin and myosin are examples of key molecules involved in cell ... Such is the case of dexamethasone-induced Ras-related protein 1 (RASD1), DNA damage-inducible transcript 4-like protein (DDIT4L ...
DDB2 (damaged-DNA binding 2) protein: a new modulator of nanomechanical properties and cell adhesion of breast cancer cells -...
To understand how DDB2 regulates these processes, an adhesion-related gene PCR-Array was performed. Several adhesion-related ... The cell stiffness decrease observed in MDA-MB231 and MCF7 expressing DDB2 was correlated with a loss of the cortical actin- ... in early events occurring during metastatic progression of breast cancer cells and will contribute to define this protein as a ... To understand how DDB2 regulates these processes, an adhesion-related gene PCR-Array was performed. Several adhesion-related ...
We previously established three mouse cell lines (Aire+TEC1, Aire+TEC2 and Aire+DC) - CXCR2 signaling in Cancer research
Proteins focus of cell lysate was identified by DC Proteins Assay (BIO-RAD). The proteins rings separated on SDS-PAGE had been ... Those clean thymocytes (mass) had been fractionated into four Ginsenoside Rb2 IC50 sub-classes relating to phrase design of ... Actin mRNA. Desk 1. Primer series of Aire, TSA and proteasome for qRT-PCR evaluation Desk 2. Primer series of TnfRsfs for qRT- ... Aire proteins was discovered with anti-Aire-pAb and visualized by ODDYSEY image resolution program (LI-COR). Break up of ...
JCI - GMPPA defects cause a neuromuscular disorder with α-dystroglycan hyperglycosylation
Mass spectrometry of skeletal muscle lysates identified proteins related to muscle contraction such as the Z-disc-related ... which anchors myofibrillar actin filaments to Z-discs. Although it is quite unspecific for myopathic disorders, staining for α- ... Western blot. Proteins were denatured at 90°C for 5 minutes in Laemmli buffer. After separation by SDS-PAGE, proteins were ... J) Mass spectrometry analysis of skeletal muscle proteins of 12-month-old WT and KO mice. Proteins significantly upregulated in ...
Publication : USDA ARS
Title: EXPRESSION OF SELECTED GENES RELATED TO LIPID METABOLISM IN BROILER BREEDER CHICKENS Author. Richards, Mark ... Expression of sterol regulatory element binding protein 1 (SREBP-1), ATP-citrate lyase (ACL), fatty acid synthase (FAS), malic ... was used to quantify hepatic expression of specific genes relative to that of b-actin in total RNA samples. ... Expression of selected genes related to lipid metabolism in broiler breeder chickens. Journal of Nutrition. 133:707-715.. ...
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It is possible some of the other novel mutations we identify will also affect proteins that may have a connection to Fragile X ... 1. Testing the genetic requirements of dfxr (Drosophila Fragile X related gene) in dendritic filopodia development. ... we are focusing on late stage dendrite development mutants including mutations affecting the development of Actin rich dendrite ... 2. Identification of genes required for normal dendritic filopodia development.. 3. Assembling genes involved in dendritic ...
System analysis based on the cuproptosis-related genes identifies LIPT1 as a novel therapy target for liver hepatocellular...
... accumulation of intracellular copper leading to the aggregation of mitochondrial lipoproteins and destabilization of proteins. ... In this study, we developed a novel prognostic model for hepatocellular carcinoma based on cuproptosis-related genes that can ... Using lasso cox regression analysis, we developed a prognostic risk model based on three cuproptosis-related genes (GCSH, LIPT1 ... However, the prognostic model of LIHC based on cuproptosis-related genes has not been reported. Firstly, we downloaded ...
TNF-related apoptosis-inducing ligand (TRAIL) is definitely a potential chemotherapeutic agent with - High-Throughput Screen...
Actin was utilized as proteins launching control. (E,F) Mz-ChA-1 had been treated with raising concentrations of Path (0C20 ng/ ... Actin was utilized as proteins launching control. After 6 hours of treatment, apoptosis was evaluated (B) by fluorescence ... TNF-related apoptosis-inducing ligand (TRAIL) is definitely a potential chemotherapeutic agent with. TNF-related apoptosis- ... Protein kinase B. Recent Posts. * G5-FA-MTX for these research was synthesized using the same multistep procedure (28) and ...
CDKN2A Interacting Protein N-Terminal Like Recombinant
... The CDKN2AIPNL solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH ... ARP3/Actin-Related Protein 3. PR27191. 20 ug. ARP3/Actin-Related Protein 3. PR27191. 5 ug. ... Activity-Regulated Cytoskeleton-Associated Protein. PR27220. 1 ug. Activity-Regulated Cytoskeleton-Associated Protein. PR27220 ... For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. ...
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... twist-related protein (Twist), zinc finger protein, Snail and Slug, involved in signaling pathways such as transforming growth ... The mechanical force used is generated by active myosin/actin contractions and cortical actin via signaling pathways such as ... the inhibition of pathways related to Rho/ROCK, such as PI3K and cell division control protein 42 homolog (CDC42)-mediated ... The two-handed E box binding zinc finger protein SIP1 down-regulates E-cadherin and induces invasion. Mol Cell 7: 1267-1278, ...
Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome - MBExC
... arm and actin-related protein (ARP) modules. The DNA-interacting module binds extra-nucleosomal DNA and is involved in the ... The structure reveals that RSC forms five protein modules and suggests key features of the remodelling mechanism. The body ... The translocase motor of the ATPase module engages with the edge of the nucleosome at superhelical location +2. The mobile ARP ...
Search WARF - WARF
The six mammalian actin genes encode a highly conserved family of cytoskeletal protein isoforms important in cell structure, ... Mouse Monoclonal Antibodies to the Human Nuclear Receptor, Estrogen-Related Receptor Alpha Estrogen-related receptor alpha ( ... Bone Morphogenetic Protein-1 Biological Materials Bone morphogenetic proteins (BMPs) are critical for the formation of ... Polyclonal Antibodies Against Equine Rhinitis A Virus 3AB, 3C and 3D Proteins Equine rhinitis A virus, formerly known as equine ...
US Patent for GEF-H1b: biomarkers, complexes, assays and therapeutic uses thereof Patent (Patent # 7,871,786 issued January 18...
The present invention relates to diagnosing abnormal cell proliferation in biological samples and screening for drugs which ... Based on the homology within the GID of PAK4 it is possible that PAK5 and PAK6 also interact with GEF-H1 or related proteins. ... Because PAK proteins and specifically PAK4 play a role in regulating F-actin based morphological structures, experiments were ... A GEF-H1-PAK complex refers to a physical interaction between the GEF-H1 protein and a PAK protein, such that the two proteins ...
β-Actin (13E5) Rabbit mAb (Alexa Fluor® 647 Conjugate) | Cell Signaling Technology
... β-Actin (13E5) Rabbit Monoclonal Antibody (Alexa Fluor® 647 Conjugate) (CST #8584) is ready to ship. ... Cited in 2 publications. Validated for Immunofluorescence (Immunocytochemistry), Flow Cytometry (Fixed/Permeabilized). Highly ... β-Actin (13E5) Rabbit mAb (Alexa Fluor® 647 Conjugate) detects endogenous levels of total β-actin protein. Depsite the high ... Explore pathways related to this product.. Select Your Pathway. Death Receptor Signaling. ...
Evaluation of Vimentin as a Potential Poor Prognostic Indicator and Salivary Biomarker for Oral Cancers and Pre-Cancers by Mass...
... a potential prognostic factor for tongue squamous cell carcinoma among five epithelial-mesenchymal transition-related proteins ... Ding L, Zhang Z, Shang D, Cheng J, Yuan H, Wu Y, Song X, Jiang H: α-Smooth muscle actin-positive myofibroblasts, in association ... Protein Identification and Mass Spectrometry (MS). Pooled tongue tissue proteins (250 µg) were separated on 18 cm IPG strips of ... Protein Visualisation and DeCyder Image analysis. The protocols for the protein visualization and image analysis using DeCyder ...
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Interactions with PIP2, ADP-actin monomers, and capping protein regulate the activity and localization of yeast twinfilin. ... If this happens to be your world, there are moon-related transmissions starting Saturday. ... Rapid fire mw 2. Professional Financing Assistance Securing auto loans that help you get into a new Chevrolet or pre-owned GMC ... I planted 3 1 gallon pots a few years ago as a windbreak warzone 2 noclip undetected the north side of mone of my orchid houses ...
Mirror-polished surface of ceria-stabilized zirconia/alumina nanocomposite enhancement in the adhesion strength of human...
... and actin (CellLight™ actin-Red Fluorescent Protein (RFP), BacMam 2.0; Thermo Fisher, USA). We stored the samples at 4°C and ... Visit for more related articles at Biomedical Research Abstract. Connective tissue sealing between the transmucosal area of the ... mRNA expression of adhesive protein. The gene expression of focal adhesion proteins represents both the development of focal ... dense actin fiber formation, and upregulated expression of collagen and fibronectin, which functions as a key scaffold protein ...
C1QBP regulates apoptosis of renal cell carcinoma via modulating xanthine dehydrogenase (XDH) mediated ROS generation
C1QBP overexpression suppresses RCC tumor growth and the expression of XDH and apoptosis-related proteins in vivo. To determine ... The expression of target protein was normalized with β-actin. ... and the expression of apoptosis-related proteins via regulating ... p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in ... Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation. Mol Cell ...
S-EPMC7216277 - Structure and Function of Filamin C in the Muscle Z-Disc. - OmicsDI
... that cross-link actin filaments and interact with numerous binding partners. FLNC consists of a N-terminal actin-binding domain ... hinge-2). The FLNC subunit is dimerized through R24 and calpain cleaves off the dimerization domain to regulate mobility of the ... is one of three filamin proteins (Filamin A (FLNA), Filamin B (FLNB), and FLNC) ... Myofibrillar Z-discs Are a Protein Phosphorylation Hot Spot with Protein Kinase C (PKC?) Modulating Protein Dynamics. ...
Amino Acid & Protein Program
11) C1Q protein. 12) caesin. 13) calcitonin gene related peptide. 14) calcium-sensing proteins. 15) calmodulin. 16) ... Proteins Assembled by Scalar Light. 1) actin. 2) albumin. 3) alpha adrenoreceptors. 4) alpha defensin. 5) alpha tubulin. 6) ... In this case, that matter is amino acids and proteins. Scalar Light™ Amino Acid & Protein Sessions run 24 hours a day for the ... Below are the lists of amino acids and proteins that are assembled by way of the Scalar Light Amino Acid and Protein Program. ...
Amino Acid & Protein Program
11) C1Q protein. 12) caesin. 13) calcitonin gene related peptide. 14) calcium-sensing proteins. 15) calmodulin. 16) ... Proteins Assembled by Scalar Light. 1) actin. 2) albumin. 3) alpha adrenoreceptors. 4) alpha defensin. 5) alpha tubulin. 6) ... Scalar Light™ Amino Acid & Protein Sessions details?. The Scalar Light™ Amino Acid & Protein Sessions broadcast instructions 24 ... In this case, that matter is amino acids and proteins. Scalar Light™ Amino Acid & Protein Sessions run 24 hours a day for the ...
Professor Derek Blake - People - Cardiff University
Coiled-coil regions in the carboxy-terminal domains of dystrophin and related proteins: potentials for protein-protein ... The adenosine A2A receptor interacts with the actin-binding protein α-actinin. Journal of Biological Chemistry 278(39), pp. ... Coiled-coil regions in the carboxy-terminal domains of dystrophin and related proteins: potentials for protein-protein ... Dystrophin and dystrophin-related proteins: a review of protein and RNA studies. Neuromuscular Disorders 3(1), pp. 5-21. ( ...
Three types of protein fibers
The cytoskeleton of a cell is made up of microtubules, actin filaments, and intermediate filaments. These structures give the ... Tubulin is a dimer consisting of two closely related 55-kd polypeptides, -tubulin and -tubulin. ... which are composed of a variety of different fibrous proteins, microtubules are composed of a single type of globular protein, ... Detailed explanation-2: -In contrast to intermediate filaments, ...
Biology Faculty Research Interests - Truman State University
Microtubule-associated proteins (MAPs) can determine the particular structural or functional roles of microtubules depending on ... Specific conserved C-terminal amino acids of Caenorhabditis elegans HMP-1/α-catenin modulate F-actin binding independently of ... I am working with students to examine questions related to the natural history, physiological ecology, and conservation of ... Reducing the expression of the Numb adaptor protein in neurons increases the searching behavior of Drosophila larvae. ...
The Cross-Communication of Cuproptosis and Regulated Cell Death in Human Pathophysiology
... a crucial regulator of lipoylation-related proteins, prevents Cu-induced cell death [25]. Cu toxicity is closely related to ... Interference with MLKL decreases capping actin protein (CAPG) content, confirming that MLKL/CAPG-induced necroptosis ... leading to the accumulation of cytotoxic protein aggregates of polyubiquitinated proteins and important proteins such as IκB, ... The regulation of mitochondrial damage through Cu imbalance triggers the activation of ATG-related proteins and promotes cell- ...