... drives PDAC from both acinar and ductal cells. Gene-expression analysis reveals further that ductal cell-derived and acinar ... Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity. Cell stem cell Yan, K. S ... Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity Cell Stem Cell Yan, K., ... Single-cell mRNA-seq revealed two subsets of Prox1-GFP+cells, one of which resembled mature EE cells while the other displayed ...

The ATP2C2 Gene as Transcribed from a Novel Transcriptional Start Site in Pancreatic Acinar Cells, Caitlin M. Sullivan ... The Role of KIM-1 Mediated Efferocytosis by Cancer Cells in Blocking the Immunogenicity of Tumor Cell Death, Sahra Nathoo ... Thylakoid Phosphorylation And Cell Morphology In The Antarctic Psychrophile, Chlamydomonas sp. UWO241, Beth Szyszka-Mroz ... The Role of Oxygen Tension and Insulin-Like Growth Factor Signaling in the Placental Mesenchymal Stem Cell Fate, Amer Youssef ...

Hu MX, Zhang HW, Fu Q, Qin T, Liu CJ, Wang YZ, Tang Q, Chen YX: Functional role of microrna-19b in acinar cell necrosis in ... Cell apoptosis and cell cycle detection. The effects of miRNA-19b-3p and MAPK1 on cell apoptosis and cell cycle distribution ... Cells in each well of 96-well plates were treated with miR-19b-3p and MAPK1. After 0, 24, 48 and 72 h incubations, cells were ... Cells were resuspended in 1× binding buffer to a final density of 1 × 105 to 5 × 105 cells/ml. Five microliters of Annexin V- ...

Pertussis toxin uncoupling-based studies have shown that Gαi and Gαo can inhibit insulin secretion in pancreatic β-cells. Yet ... 1). We do not detect Gαo in exocrine acinar or pancreatic duct cells (Fig. 1 and data not shown). Further RT-PCR analyses ... αo-deficient β-cells have a significant increase in cell membrane-docked insulin vesicles as compared with control cells. These ... 4), Gαo mutant β-cells release significantly more vesicles than control β-cells (Fig. 7,A). In this regard, it is possible that ...

Epimorphin/Syntaxin 2 293T Cell Transient Overexpression Lysate. Tested Reactivity: Hu. Validated: WB. Backed by our 100% ... Studies using pancreatic exocrine acinar cells, in which the exocytic pathways are well defined, show primary localization of ... Epimorphin/Syntaxin 2 293T Cell Transient Overexpression Lysate Summary. Description. Quality control test: Transient ... Be the first to review our Epimorphin/Syntaxin 2 293T Cell Transient Overexpression Lysate and receive a gift card or discount. ...

All three enzymes are synthesized by the pancreatic acinar cells, secreted in the small intestine and are responsible for ...

... and obstruction of the pancreatic duct lead to the formation of large intracellular vacuoles in acinar cells. Vacuole formation ... CCK is normally released by cells in the duodenum in response to intraluminal fat and amino acids and coordinates and ...

... resulting in acinar cell and pancreatic capillary injury (6,7). Another hypothesis is chylomicronemia-induced hyperviscosity in ... and white blood cell (WBC) count. Laboratory data during the run-in period were also extracted to calculate the mean values of ...

Different types of acinar epithelial cells (breast epithelial cells, salivary gland cells, pancreatic and prostate cells) form ... The iPS cells are able to differentiate to any type of cell, just like embryonic stem cells, but since the progenitor cells are ... Stem cell function, self-renewal, and behavioral heterogeneity of cells from the adult muscle satellite cell niche. Cell 2005; ... Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell 2009;5( ...

Acinar Cell 33% * Autoradiograph 33% * Cells 66% * DNA Synthesis 100% * Endocrine Pancreas 100% ...

Biopsy shows the acinar cells to be enlarged to almost twice the normal diameter and the cytoplasm packed with enzyme granules ... B cells with cell surface RF can concentrate immune complexes and present antigens to CD4+ T cells. The acini are destroyed by ... Continued cell division of specific B cells leads to oligoclonal expansion and increased chance of karyotypic error associated ... CD4+ T cells recognize these antigens and release a series of cytokines, which promote further T-cell activation. ...

HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer ...

NHE1, the most well characterized NHE isoform, mediates transepithelial transport in secretory parotid acinar cells and may ... Unlike the other NHE isoforms, NHE3 is recycled between apical membranes and the endosomal compartment of epithelial cells ... This poster summarizes the main metabolic pathways in cancer cells and highlights potential targets for cancer therapeutics. ... Our Cancer Metabolism poster summarizes the main metabolic pathways in cancer cells, and highlights potential targets for ...

... as evidenced by the damaged structure and function of pancreatic cells called acinar cells - specialised structures that ... The GM-fed rats started showing harmful changes to the pancreatic acinar cells as soon as five days after starting the GM soy ... inflammation and death of acinar cells), which, however, the authors dismissed as unrelated to the GM diet. The Mexican study, ... However, they recovered after 30 days, while still on the GM soy diet, as the changes in pancreatic cells returned to normal. ...

Induced PTF1a Expression in Pancreatic Ductal Adenocarcinoma Cells Activates Acinar Gene Networks, Reduces Tumorigenic ... Aguilar Lab - "Use of induced pluripotent stem cells from Lowe syndrome patients provide insight into disease mechanism". 2018- ... Konieczny Lab has developed a new strategy to induce terminal differentiation of pancreatic cancer cells.. 2018-05-22 ... "Use of induced pluripotent stem cells from Lowe syndrome patients provide insight into disease mechanism" ...

Tumorigenic Potential In an oral carcinogenicity study, gabapentin enacarbil increased the incidence of pancreatic acinar cell ... Except cannabis isnt toxic and stores in fat cells. If it was flushed with detoxifying it would not get people fired with ...

Ca++-dependent disassembly and reassembly of occluding junctions in guinea pig pancreatic acinar cells ... Cells were either untreated or treated for 40 h with 10 μM OCC1 or 10 μM OCC2. Subsequently, the cells were rinsed twice in PBS ... At t = 24 h, peptides were either replenished (OCC1 and OCC2) or removed (OCC2 recovery) from the cells. At t = 60 h, cells ... At t = 24 h, peptides were either replenished (OCC1 and OCC2) or removed (OCC2 recovery) from the cells. At t = 60 h, cells ...

Cytomorphologic, immunophenotypical and molecular features of pancreatic acinar cell carcinomaSun T, Gilani S, Jain D, Cai G. ... Small-Cell Carcinoma Versus Atypical Carcinoid TumorYoon E, Zhang X, Cai G. Small-Cell Carcinoma Versus Atypical Carcinoid ... Atypical Carcinoid Tumor Versus Large-Cell Neuroendocrine CarcinomaYoon E, Cai G. Atypical Carcinoid Tumor Versus Large-Cell ... immunophenotypical and molecular features of pancreatic acinar cell carcinoma. Diagnostic Cytopathology 2023 PMID: 37469257, ...

After confirming she had EPI (This is the inability of the acinar cells of the exocrine pancreas to produce and secrete the ...

... in which the FDA indicated that a preclinical finding of pancreatic acinar cell tumors in rats was of sufficient concern to ...

... with smears showing cells arranged in loose cohesive clusters and singly with acinar/follicles/rosette formations. Tumor cells ... a and b) Cellular smears showing loose cohesive clusters of tumor cells with acinar follicular pattern in a background of ... The tumor cells were arranged in focal acinar or follicular pattern with a round-to-oval nucleus, moderate anisonucleosis, fine ... High power showing round-to-oval nucleus with moderate anisonucleosis and bizarre cell (MGG, ×400). (d) Tumor cell showing fine ...

A Model of Calcium Waves in Pancreatic and Parotid Acinar Cells ©. 2001-2023 - The CellML Project. ...

Rare pancreatic tumors including acinar cell carcinoma, mucinous cystadenocarcinoma or serous cystadenocarcinoma. Pancreatic ... Transitional cell carcinoma other than that of the renal, pelvis, ureter, or bladder (closed to accrual) 16. Cell tumor of the ... Squamous cell carcinoma variants of the genitourinary (GU) system 19. Spindle cell carcinoma of kidney, pelvis, ureter 20. ... Clear cell endometrial cancer 46. Clear cell ovarian cancer (closed to accrual) 47. Gestational trophoblastic disease (GTD) 48 ...

... fibro-inflammatory disease characterized by enzymatic autoactivation and subsequent fibrotic replacement of acinar cells. A ... fibro-inflammatory disease characterized by enzymatic autoactivation and subsequent fibrotic replacement of acinar cells. A ... suggesting improved duct cell function compared to placebo [17]. This study did not distinguish between subjects with AP, ... protease inhibitors reduced the migration of cathepsin B-containing auto-digestive enzymes to the periphery of the cell, a key ...

Ferdek et al (2017) BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca ... Also blocks cell membrane-located capsaicin-activated cation channels (IC50 = 14 nM) and voltage-sensitive Ca2+ channels to ... Battefeld et al (2019) High-Frequency Microdomain Ca2+ Transients and Waves during Early Myelin Internode Remodeling. Cell Rep ... These cells elicit store-overload induced Ca2+ release (cytosolic oscillations) via RyR2 in presence of 2 mM extracellular Ca2+ ...

Colorized transmission electron micrograph (TEM) of rough endoplasmic reticulum (ER) from an acinar cell in the pancreas. ... cell-cell adhesion Cellular Component. cell surface Colorized scanning electron micrograph showing two lung cancer cells. These ... cell-cell adhesion Cellular Component. cell surface Scanning electron micrograph of pancreatic cancer cells. See additional ... substrate-dependent cell migration, cell attachment to substrate Cellular Component. cell surface Colorized scanning electron ...

Mouse: ESC, NPCs, BZ, GT1-7, acinar cells, HSPCs, Th2 cells, keratinocytes ... ChIP-seq on cells. Figure 1. (A) Chromatin Immunoprecipitation has been performed using chromatin from HeLa cells, the iDeal ... Cell lines:. Human: A549, A673, BT-549, CD4 T, HCC1806, HeLa, HepG2, HFF, HK-GFP-MR, ILC, K562, KYSE-180, LapC4, M14, MCF7, MDA ... Species, cell lines, tissues tested. The iDeal ChIP-seq Kit for Transcription Factors is compatible with a broad variety of ...

Pancreatic Acinar Cell Carcinoma , Pancreatic Adenosquamous Carcinoma , Pancreatic Squamous Cell Carcinoma ... Non-small Cell Lung Cancer , Head and Neck Squamous Cell Carcinoma , Esophageal Squamous Cell Carcinoma ... ... Melanoma , Renal Cell Carcinoma , Cervical Cancer , Small Cell Lung Cancer , Gastric Cancer , Colorectal Cancer , Esophageal ... Advanced Non-squamous Non-small-cell Lung Cancer , Metastatic Non-squamous Non Small Cell Lung Cancer , Recurrent Non-Squamous ...

The nuclei of acinar cells and some islet precursor cells stain positive for PTF1A. All images were analyzed using a BD Pathway ... The nuclei of acinar cells and some islet precursor cells stain positive for PTF1A. All images were analyzed using a BD Pathway ... The nuclei of acinar cells and some islet precursor cells stain positive for PTF1A. All images were analyzed using a BD Pathway ... 5. Stain cells for 5-15 minutes at a cell density of 1 - 2 x 10^6 cells/mL. No further wash is necessary prior to analysis. ...

... of pancreatic enzymes have been suggested to be explained by increased DNA or protein synthesis found in rodent and acinar cell ...