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*  Structural impact of human and Escherichia coli biotin carboxyl carrier proteins on biotin attachment. - The Kennedy Institute...
... the biotin-attachment domain fragments from human propionyl-CoA carboxylase and E. coli acetyl-CoA carboxylase, respectively. ... This study suggests that the thumb loop found in bacterial carboxylases interferes with optimal interaction with the mammalian ... that is found in carboxylases in most organisms. Numerous studies have indicated that HCS and BirA, as well as biotin protein ... the biotin-attachment domain fragments from human propionyl-CoA carboxylase and E. coli acetyl-CoA carboxylase, respectively. ...
https://www.kennedy.ox.ac.uk/publications/108531
*  Studies on acetyl-CoA carboxylase and fatty acid synthase from rat mammary gland and mammary tumours | Biochemical Journal
Studies on acetyl-CoA carboxylase and fatty acid synthase from rat mammary gland and mammary tumours. P M Ahmad, D S Feltman, F ... Studies on acetyl-CoA carboxylase and fatty acid synthase from rat mammary gland and mammary tumours ... On the other hand, in tumours carried by lactating dams there were only modest increases (1.5-2-fold) in acetyl-CoA carboxylase ... Studies on acetyl-CoA carboxylase and fatty acid synthase from rat mammary gland and mammary tumours ...
http://www.biochemj.org/content/208/2/443
*  Native Bovine Pyruvate Carboxylase - Creative Enzymes
Pyruvate carboxylase is a mitochondrial protein that has a biotin prosthetic group that requ ... Pyruvate carboxylase catalyzes the carboxylation of pyruvate to oxaloacetate. ... carboxylase is a mitochondrial protein that has a biotin prosthetic group that requiries magnesium or manganese and acetyl CoA. ... The enzyme from Creative Enzymes has been used as a positive control during the assay of pyruvate carboxylase activity in cell- ...
https://www.creative-enzymes.com/product/Native-Bovine-Pyruvate-Carboxylase_1428.html
*  Genetic Polymorphism Detection of the Exon 1 Region of Acetyl-CoA Carboxylase Alpha Gene in Iranian Mahabadi Goat Breed
Acetyl-coenzyme A carboxylase α (ACC-alpha) is considered as the key regulatory enzyme in fatty acid biosynthesis. ACC-alpha ... CoA carboxylase α gene (ACC-alpha) and can catalyze irreversible carboxylation of Acetyl-coA for producing malonyl-CoA (Badaoui ... Acetyl-CoA carboxylase α (ACC-alpha) is the key regulatory enzyme in fatty acid biosynthesis. This biotin-dependent enzyme is ... Barber M.C., Price N.T. and Travers M.T. (2005). Structure and regulation of acetyl-CoA carboxylase genes of metazoa. Biochim. ...
http://ijas.iaurasht.ac.ir/article_516657.html
*  Ligand-induced conformational transitions and secondary-structure composition of chicken liver pyruvate carboxylase |...
The rates of quenching by acetyl-CoA and MgATP (in the presence of acetyl-CoA) were too rapid to measure by stopped-flow ... acetyl-CoA, 10-13%; ATP, 21-24%; acetyl-CoA plus ATP, about 35%. Additions of KHCO3 had no effect on the fluorescence. ... Additions of acetyl-CoA and/or ATP to the enzyme-probe solutions quenched fluorescence of the probe by the following cumulative ... In contrast with results with 8-anilinonaphthalene-1-sulphonic acid, fluorescence of the ε-derivative of acetyl-CoA or ATP [ ...
http://www.biochemj.org/content/177/2/697
*  Acetyl-CoA carboxylase (IPR034733) | InterPro | EMBL-EBI
In bacteria, the acetyl coenzyme A carboxylase (ACC) is a complex consisting of two subunits: alpha and beta. This domain also ... One of them uses acyl-CoA and the other uses 2-oxoacid as the acceptor molecule of carbon dioxide. All of the members in this ... All of the members in this family are biotin dependent carboxylases [PMID: 8102604, PMID: 8366018]. The carboxyl transferase ... Molecular evolution of biotin-dependent carboxylases.. Eur. J. Biochem. 215 687-96 1993 ...
https://www.ebi.ac.uk/interpro/entry/IPR034733
*  Targeting Acetyl-CoA Carboxylase to Stay Lean | Science Signaling
Acetyl-CoA carboxylase (ACC) regulates synthesis and oxidation of fatty acids, and mice lacking the ACC2 isoform are leaner ... Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and ...
http://stke.sciencemag.org/content/2007/409/tw387
*  PREDICTED: acetyl-CoA carboxylase isoform X2 [Microplitis demolitor] - Protein - NCBI
Record removed. This record was removed as a result of standard genome annotation processing. Please see www.ncbi.nlm.nih.gov/genome/annotation_euk/process/ for more information. ...
https://www.ncbi.nlm.nih.gov/protein/XP_008546338.1
*  Anti-Acetyl CoA Carboxylase Antibody, Unconjugated from Cell Signaling Technology
Acetyl CoA Carboxylase Antibody,biological,biology supply,biology supplies,biology product ... Anti-Acetyl CoA Carboxylase Antibody, Unconjugated from Cell Signaling Technology, ... Acetyl CoA Carboxylase Antibody. Info. Cell Signaling Technology. Cell Signaling Technology, Inc. 3 Trask Lane Danvers, MA ... Rat Anti-Acetyl Salicylic Acid conjugated Acetyl Salicylic Acid Polyclonal Antibody, Unconjugated from Cell Sciences. 4. Mouse ...
http://www.bio-medicine.org/biology-products/Anti-Acetyl-CoA-Carboxylase-Antibody--Unconjugated-from-Cell-Signaling-Technology-5285-1/
*  CST - Phospho-Acetyl-CoA Carboxylase (Ser79) (D7D11) Rabbit mAb
... phosphate/acetyl-CoA carboxylase 2 (Ser222) phosphate in the Metabolism research area. ... Monoclonal Antibody for studying acetyl-CoA carboxylase 1 (Ser80) ... Acetyl-CoA carboxylase (ACC) catalyzes the carboxylation of acetyl-CoA to malonyl-CoA (1). It is the key enzyme in the ... Phospho-Acetyl-CoA Carboxylase (Ser79) (D7D11) Rabbit mAb recognizes endogenous levels of acetyl-CoA carboxylase protein only ...
https://www.cellsignal.com/products/primary-antibodies/phospho-acetyl-coa-carboxylase-ser79-d7d11-rabbit-mab/11818?N=102236+4294960669+4294956287&fromPage=plp
*  accA acetyl-CoA carboxylase carboxyl transferase subunit alpha [Streptococcus mutans UA159] - Gene - NCBI
acetyl-CoA carboxylase carboxyl transferase subunit alpha. Locus tag. SMU_1734. Gene type. protein coding. RefSeq status. ... acetyl-CoA carboxylase carboxyl transferase subunit alpha. NP_722061.1. *Best Blastp Hit: gb,AAF98281.1,AF197933_11 (AF197933) ... accA acetyl-CoA carboxylase carboxyl transferase subunit alpha [ Streptococcus mutans UA159 ] Gene ID: 1028945, updated on 15- ... NP_722061.1 acetyl-CoA carboxylase subunit alpha [Streptococcus mutans UA159]. See identical proteins and their annotated ...
https://www.ncbi.nlm.nih.gov/gene?term=SMU.1734
*  anti-Acetyl-CoA Carboxylase 1 antibody | GeneTex
... acetyl-CoA carboxylase alpha) for ICC/IF, IHC-P, WB. Anti-Acetyl-CoA Carboxylase 1 pAb (GTX132081) is tested in Human, Mouse, ... Acetyl CoA Carboxylase 1 antibody , Acetyl CoA Carboxylase 1 antibody , acetyl-CoA carboxylase alpha antibody. ... acetyl-CoA carboxylase alpha. Background. Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a ... Green: Acetyl CoA Carboxylase 1 protein stained by Acetyl CoA Carboxylase 1 antibody (GTX132081) diluted at 1:500.. Blue: ...
http://www.genetex.com/Acetyl-CoA-Carboxylase-1-antibody-GTX132081.html
*  Acetyl CoA carboxylase | definition of acetyl CoA carboxylase by Medical dictionary
What is acetyl CoA carboxylase? Meaning of acetyl CoA carboxylase medical term. What does acetyl CoA carboxylase mean? ... Looking for online definition of acetyl CoA carboxylase in the Medical Dictionary? acetyl CoA carboxylase explanation free. ... acetyl CoA carboxylase. acetyl CoA carboxylase. a biotin-containing enzyme which participates in the synthesis of fatty acids ... gland of lactating mice was caused by reducing acetyl CoA carboxylase activity and mRNA abundance of acetyl CoA carboxylase, ...
https://medical-dictionary.thefreedictionary.com/acetyl+CoA+carboxylase
*  Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase (Journal Article) | DOE PAGES
We found that Acetyl-CoA carboxylase (ACC) inhibitors offer significant potential for the treatment of type 2 diabetes mellitus ... Acetyl-CoA carboxylase (ACC) inhibitors offer significant potential for the treatment of type 2 diabetes mellitus (T2DM), ... Biotin Attachment Domain-Containing Proteins Irreversibly Inhibit Acetyl CoA Carboxylase Journal Article Keereetaweep, Jantana ... Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the ...
https://www.osti.gov/pages/biblio/1250604-discovery-spirocyclic-diamine-inhibitors-mammalian-acetyl-coa-carboxylase
*  ACC1 - Acetyl-CoA carboxylase 1 - Oryza sativa subsp. japonica (Rice) - ACC1 gene & protein
... forming malonyl-CoA, which is used in the plastid for fatty acid synthesis and in the cytosol in various biosynthetic pathways ... Multifunctional enzyme that catalyzes the carboxylation of acetyl-CoA, ... Acetyl-CoA carboxylase 1 (ACC1), Acetyl-CoA carboxylase 2 (ACC2). This subpathway is part of the pathway malonyl-CoA ... Acetyl-CoA carboxylase 1Add BLAST. 2267. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical view ...
http://www.uniprot.org/uniprot/Q8S6N5
*  Acetyl-CoA Carboxylase alpha ELISA & Assay Kits
Compare and order Acetyl-CoA Carboxylase alpha ELISA Kits. View citations, images, detection ranges, sensitivity, prices and ... acetyl-CoA carboxylase 1 , acetyl-coenzyme A carboxylase alpha , acetyl-CoA carboxylase-alpha , ACC , acetyl-CoA carboxylase , ... Acetyl-CoA Carboxylase alpha Antigen Profile Antigen Summary Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme ... Acetyl-CoA Carboxylase alpha in AMPK Signaling * Acetyl-CoA Carboxylase alpha in AMPK Signaling ...
https://www.antibodies-online.com/ampk-signaling-pathway-15/acetyl-coa-carboxylase-alpha-elisa-kit-2004/
*  Human Acetyl-CoA Carboxylase alpha ELISA Kit | Product No. ABIN810228
Order Acetyl-CoA Carboxylase alpha ELISA Kit ABIN810228. ... Acetyl-CoA Carboxylase alpha ELISA Kit Human for Plasma, Cell ... Acetyl-CoA Carboxylase alpha ELISA Kit (ACACA) Acetyl-CoA Carboxylase alpha ELISA Kit (ACACA). Details for Product ACACA ELISA ... More product categories related to Acetyl-CoA Carboxylase alpha Kit * 154 anti-Acetyl-CoA Carboxylase alpha Primary Antibodies ... Synonyms: ACAC, ACC, ACC1, ACCA, ACC-alpha,acetyl-CoA carboxylase 1,acetyl-CoA carboxylase-alpha ...
https://www.antibodies-online.com/kit/810228/Acetyl-CoA+Carboxylase+alpha+ACACA+ELISA+Kit/
*  Acetyl-CoA carboxylase - Wikipedia
Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to ... Lee CK, Cheong HK, Ryu KS, Lee JI, Lee W, Jeon YH, Cheong C (August 2008). "Biotinoyl domain of human acetyl-CoA carboxylase: ... Boone AN, Chan A, Kulpa JE, Brownsey RW (April 2000). "Bimodal Activation of Acetyl-CoA Carboxylase by Glutamate". J Biol Chem ... Brownsey RW, Boone AN, Elliott JE, Kulpa JE, Lee WM (April 2006). "Regulation of acetyl-CoA carboxylase". Biochem. Soc. Trans. ...
https://en.wikipedia.org/wiki/Acetyl-CoA_carboxylase
*  acetyl-CoA carboxylase)-phosphatase - Wikipedia
... acetyl-CoA carboxylase]-phosphatase (EC 3.1.3.44) is an enzyme that catalyzes the chemical reaction [acetyl-CoA carboxylase] ... acetyl-CoA carboxylase] + phosphate Thus, the two substrates of this enzyme are acetyl-CoA carboxylase phosphate and H2O, ... Krakower GR; Kim K-H (1980). "Purification and properties of acetyl-CoA carboxylase phosphatase". J. Biol. Chem. 256 (5): 2408- ... whereas its two products are acetyl-CoA carboxylase and phosphate. This enzyme belongs to the family of hydrolases, ...
https://en.wikipedia.org/wiki/(acetyl-CoA_carboxylase)-phosphatase
*  The Role of Phosphorylation in the Regulation of Acetyl-CoA Carboxylase Activity by Insulin and other Hormones | SpringerLink
Insulin stimulates fatty acid synthesis in adipose and other tissues by increasing acetyl-CoA carboxylase activity. 1,2,3,4, ... R.W. Brownsey, W.A. Hughes, R.M. Denton and R.J. Mayer, Demon stration of the phosphorylation of acetyl-CoA carboxylase within ... A.L. Witters, D. Moriarty, and D.B. Martin, Regulation of hepatic acetyl-CoA carboxylase by insulin and glucagon, Biol. Chem. ... R.W. Brownsey, W.H. Hughes, and R.M. Denton, Adrenaline and the regulation of acetyl-CoA carboxylase in rat epididymal adipose ...
https://link.springer.com/chapter/10.1007/978-1-4757-0166-1_31
*  Biotin-(acetyl-CoA-carboxylase) ligase - Wikipedia
... acetyl-CoA carboxylase] synthetase, biotin-[acetyl coenzyme A carboxylase] synthetase, acetyl coenzyme A holocarboxylase ... acetyl-CoA-carboxylase] ligase (EC 6.3.4.15) is an enzyme that catalyzes the chemical reaction ATP + biotin + apo-[acetyl-CoA: ... acetyl-CoA:carbon-dioxide ligase (ADP-forming)] The 3 substrates of this enzyme are ATP, biotin, and apo-[acetyl-CoA:carbon- ... The systematic name of this enzyme class is biotin:apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] ligase (AMP-forming). ...
https://en.wikipedia.org/wiki/Biotin%E2%80%94(acetyl-CoA-carboxylase)_ligase
*  Frontiers | Study of Fitness Cost in Three Rigid Ryegrass Populations Susceptible and Resistant to Acetyl-CoA Carboxylase...
2007). Single-site mutations in the carboxyl transferase domain of plastid acetyl-CoA carboxylase confer resistance to grass- ... Study of Fitness Cost in Three Rigid Ryegrass Populations Susceptible and Resistant to Acetyl-CoA Carboxylase Inhibiting ... Nine distinguished aminoacid replacements in the CT domain of plastidic Acetyl-COA carboxylase genes have been identified to ... Study of Fitness Cost in Three Rigid Ryegrass Populations Susceptible and Resistant to Acetyl-CoA Carboxylase Inhibiting ...
https://www.frontiersin.org/articles/10.3389/fevo.2016.00142/full
*  Abstract 4452: Liver selective acetyl-CoA carboxylase inhibition by ND-654 improves survival in cirrhotic rats with...
Liver selective acetyl-CoA carboxylase inhibition by ND-654 improves survival in cirrhotic rats with hepatocellular carcinoma ... Simultaneous inhibition of the acetyl-CoA carboxylase isozymes, ACC1 and ACC2, results in concomitant inhibition of fatty acid ... Abstract 4452: Liver selective acetyl-CoA carboxylase inhibition by ND-654 improves survival in cirrhotic rats with ... Abstract 4452: Liver selective acetyl-CoA carboxylase inhibition by ND-654 improves survival in cirrhotic rats with ...
http://cancerres.aacrjournals.org/content/75/15_Supplement/4452
*  Abstract 1048: Modulation of lipid metabolism through inhibition of acetyl-CoA carboxylase with ND-646 leads to potent...
The rate-limiting enzyme in fatty acid synthesis, acetyl-CoA carboxylase (ACC), has been shown to be highly expressed in human ... Modulation of lipid metabolism through inhibition of acetyl-CoA carboxylase with ND-646 leads to potent inhibition of breast ... Abstract 1048: Modulation of lipid metabolism through inhibition of acetyl-CoA carboxylase with ND-646 leads to potent ... Abstract 1048: Modulation of lipid metabolism through inhibition of acetyl-CoA carboxylase with ND-646 leads to potent ...
http://cancerres.aacrjournals.org/content/76/14_Supplement/1048