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Acetoacetate activation of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in primary ... Jain SK, Kannan K, Lim G. Ketosis (acetoacetate) can generate oxygen radicals and cause increased lipid peroxidation and growth ... In this context, it has been shown that the ketone body acetoacetate, through increased oxidative stress, regulates gene ... Polyunsaturated fatty acids and acetoacetate downregulate the expression of the ATP-binding cassette transporter A1. Diabetes ...
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Correlation analysis between 24 plasma biomarker candidates, including glycogenic amino acids and acetoacetate, and brain ... acetoacetate, decreased immediately after exercise (post-0 h) and increased 6 h after exercise (post-6 h) (upper-left quadrant ... acetoacetate, decreased immediately after exercise (post-0 h) and increased 6 h after exercise (post-6 h). ...
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Seizure reduction was correlated with acetoacetate level (rb=−0.238, p , 0.036) and BOH level (r=−0.312, p , 0.01) at 3 months. ... The classical ketogenic diet group had a significantly higher mean acetoacetate level than the MCT group at 3, 6, and 12 months ... The conversion leads to the synthesis of three ketone bodies in particular: β-hydroxybutyrate, acetoacetate, and acetone. ...