Aurich, Harald (1961). "Über die β-Alanin-α-Ketoglutarat-Transaminase aus Neurospora crassa" [On the beta-alanine-alpha- ... Scott, E. M; Jakoby, W. B (1959). "Soluble γ-Aminobutyric-Glutamic Transaminase from Pseudomonas fluorescens". The Journal of ... Gibson, K; Vogel, Kara; Parviz, Mahsa; Pearl, Phillip (2015). "Disorders of GABA metabolism: SSADH and GABA-transaminase ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The ...
... pyruvate transaminase (EC 2.6.1.96, aminobutyrate aminotransferase, gamma-aminobutyrate aminotransaminase, gamma-aminobutyrate ... aminobutyrate transaminase, GABA aminotransferase, GABA transaminase, GABA transferase, POP2 (gene)) is an enzyme with ... gamma-aminobutyric acid pyruvate transaminase, gamma-aminobutyric acid transaminase, gamma-aminobutyric transaminase, 4- ... and potential functions for an Arabidopsis γ-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate". J. Exp. ...
tr,A0A0B6ASF7,A0A0B6ASF7_BACMB 4-aminobutyrate transaminase OS=Bacillus megaterium (strain ATCC 14581 / DSM 32 / JCM 2506 / ... 4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., ...
GABA-transaminase, GABA-T, EC 2.6.1.19) deficiency (McKusick 137150), an inborn error of GABA degradation, has until now been ... A neuron-glia interaction involving GABA Transaminase contributes to sleep loss in sleepless mutants. *W Chen, Sarah E. Maguire ... Identification of a Familial Mutation Associated with GABA-Transaminase Deficiency Disease. *Lali K. Medina-Kauwe, William L. ... Essential arginine residues at the pyridoxal phosphate binding site of brain gamma-aminobutyrate aminotransferase.. *Godfrey ...
14 (4): 280-6. doi:10.1038/nsmb1228. PMID 17384644.. *^ a b c Battaglioli G, Liu H, Martin DL (August 2003). "Kinetic ... doi:10.1016/S1474-4422(11)70039-4. PMID 21419704.. *^ Manto MU, Hampe CS, Rogemond V, Honnorat J (February 2011). "Respective ... doi:10.1016/S1381-1177(00)00114-4.. *^ Feldblum S, Erlander MG, Tobin AJ (April 1993). "Different distributions of GAD65 and ... Several truncated transcripts and polypeptides of GAD67 are detectable in the developing brain,[4] however their function, if ...
ISBN 978-0-470-12316-4. PMID 8638482.. *^ a b c Nagatsu T (1995). "Tyrosine hydroxylase: human isoforms, structure and ... 4 (7): 578-85. doi:10.1038/nsb0797-578. PMID 9228951.. *^ Goodwill KE, Sabatier C, Stevens RC (Sep 1998). "Crystal structure of ... 14 (4): 455-67. doi:10.2174/092986707779941023. PMID 17305546.. *^ Thöny B, Auerbach G, Blau N (Apr 2000). "Tetrahydrobiopterin ... 26 (22): 6910-4. doi:10.1021/bi00396a007. PMID 2892528.. *. Le Bourdellès B, Boularand S, Boni C, Horellou P, Dumas S, Grima B ...
GABA-transaminase deficiency. At least 10 mutations in the ABAT gene have been identified in people with GABA-transaminase ... The ABAT gene mutations that cause GABA-transaminase deficiency lead to a shortage (deficiency) of functional GABA-transaminase ... The ABAT gene provides instructions for making the GABA-transaminase enzyme. This enzyme helps break down a brain chemical ( ... Phenotype of GABA-transaminase deficiency. Neurology. 2017 May 16;88(20):1919-1924. doi: 10.1212/WNL.0000000000003936. Epub ...
gamma aminobutyrate transaminase deficiency. *gamma aminobutyric acid transaminase deficiency. *gamma-aminobutyrate ... GABA-transaminase deficiency is caused by mutations in the ABAT gene, which provides instructions for making the GABA- ... GABA-transaminase deficiency is a very rare disorder. Only a small number of affected individuals have been described in the ... Mutations in the ABAT gene lead to a shortage (deficiency) of functional GABA-transaminase enzyme. As a result, GABA is not ...
PIRSF000521. Transaminase_4ab_Lys_Orn. 2 hits. Superfamily database of structural and functional annotation ... 4-aminobutyrate aminotransferaseImported. ,p>Information which has been imported from another database using automatic ... tr,A0QV88,A0QV88_MYCS2 4-aminobutyrate aminotransferase OS=Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) OX=246196 GN ... 4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., ...
4-aminobutyrate Transaminase. An enzyme that converts brain gamma-aminobutyric acid (GAMMA-AMINOBUTYRIC ACID) into succinate ... It is an irreversible inhibitor of 4-AMINOBUTYRATE TRANSAMINASE, the enzyme responsible for the catabolism of GAMMA- ...
Green: Adenosylmethionine-8-amino-7-oxononanoate transaminase. Red: 3-aminobutyryl-CoA transaminase. Orange: glutamate-1- ... A novel acyl-CoA beta-transaminase characterized from a metagenome.. Perret A1, Lechaplais C, Tricot S, Perchat N, Vergne C, ... Yellow: diaminobutyrate-2-oxoglutarate transaminase. Pink: taurine-pyruvate aminotransferase. Blue: ornithine, acetylornithine ... Figure 4. Structure of the different NAC-thioesters and their corresponding products after β-transamination catalyzed by Kat in ...
DR Pfam; PF00202; Aminotran_3; 1. DR PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2. DR SUPFAM; SSF53383; SSF53383; 1. DR ... DE SubName: Full=4-aminobutyrate transaminase {ECO:0000313,EMBL:AJE81965.1}; GN ORFNames=SLNWT_1589 {ECO:0000313,EMBL: ... DR GO; GO:0003867; F:4-aminobutyrate transaminase activity; IEA:InterPro. DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA ...
DR Pfam; PF00202; Aminotran_3; 1. DR PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2. DR SUPFAM; SSF53383; SSF53383; 1. DR ... Ontology (3) GO (3) Gene (4) KEGG ORTHOLOGY (1) KEGG GENES (1) NCBI-Gene (2) Protein sequence (2) RefSeq(pep) (2) DNA sequence ... DR GO; GO:0003867; F:4-aminobutyrate transaminase activity; IEA:InterPro. DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA ... 1) EMBL (1) Protein domain (6) InterPro (4) Pfam (1) PROSITE (1) Literature (1) PubMed (1) All databases (17) Download RDF ...
4-Aminobutirato Transaminase/metabolismo. Animais. Anticonvulsivantes/s ntese qu mica. Anticonvulsivantes/qu mica. Rela o Dose- ... 4-Aminobutirato Transaminase/antagonistas & inibidores. Anticonvulsivantes/farmacologia. Desenho de Drogas. Inibidores Enzim ...
546-9. ISBN 978-0-7817-5745-4.. *↑ Miller RD (2005). Millers Anesthesia (6th ed.). Philadelphia, Penns.: Elsevier/Churchill ... 487-8. ISBN 978-0-443-06618-4.. *↑ Leuzinger W, Baker AL (Feb 1967). "Acetylcholinesterase, I. Large-scale purification, ...
4 (7): 578-85. doi:10.1038/nsb0797-578. PMID 9228951.. *↑ Goodwill KE, Sabatier C, Stevens RC (Sep 1998). "Crystal structure of ... 14 (4): 455-67. doi:10.2174/092986707779941023. PMID 17305546.. *↑ Thöny B, Auerbach G, Blau N (Apr 2000). "Tetrahydrobiopterin ... 26 (22): 6910-4. doi:10.1021/bi00396a007. PMID 2892528.. *. Le Bourdellès B, Boularand S, Boni C, Horellou P, Dumas S, Grima B ... Tyrosine hydroxylase catalyzes the reaction in which L-tyrosine is hydroxylated in the meta position to obtain L-3,4- ...
4 (6): 545-51. doi:10.1038/sj.mp.4000559. PMID 10578236.. *↑ Lauritsen MB, Børglum AD, Betancur C, Philippe A, Kruse TA, ... Biosynthetic pathways for catecholamines and trace amines in the human brain[3][4][5] ...
Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, ... Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate ... using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards ... phosphate concentration and the erythrocyte aspartate transaminase stimulation test in lactating mothers and their infants. Am ...
Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate ... L-2,4-diaminobutyric acid. Description. L-3-Amino-isobutanoic acid is a component of branched-chain amino acid biosynthesis and ... 1. 4-aminobutyrate aminotransferase, mitochondrial. General function:. Involved in 4-aminobutyrate transaminase activity. ... Showing metabocard for L-2,4-diaminobutyric acid (HMDB0006284). IdentificationTaxonomyOntologyPhysical propertiesSpectra ...
Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate ... L-2,4-diaminobutyric acid is a very strong basic compound (based on its pKa). Outside of the human body, L-2,4-diaminobutyric ... Showing metabocard for L-2,4-diaminobutyric acid (HMDB0006284). Jump To Section: IdentificationTaxonomyOntologyPhysical ... L-2,4-diaminobutyric acid. Description. L-2,4-diaminobutyric acid, also known as Dbu or alpha,gamma-diaminobutyrate, belongs to ...
2.6.1.22 (S)-3-amino-2-methylpropionate transaminase. A6J81_22935. 2.6.1.48 5-aminovalerate transaminase. A6J81_22935. Amino ... 3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]. ... 2.6.1 Transaminases. 2.6.1.19 4-aminobutyrate---2-oxoglutarate transaminase. A6J81_22935. ...
bpl:BURPS1106A_3101 beta-alanine--pyruvate transaminase K00822 442 550 ( -) 131 0.312 410 -, bpl:BURPS1106A_0412 ... bpl:BURPS1106A_2785 succinylornithine transaminase K00840 410 742 ( -) 175 0.365 417 -, bpl:BURPS1106A_0532 2,4-diaminobutyrate ... 4-aminobutyrate transaminase; K00823 4-aminobutyrate aminotransferase. Update status:. T00480 (apre,bapi,bgg,bhan,bths,cchv,ceh ... bpl:BURPS1106A_A2215 2,4-diaminobutyrate 4-transaminase K00836 927 677 ( -) 160 0.340 406 -, bpl:BURPS1106A_A3154 ...
Furthermore astrocytes are indispensible for glutamatergic and γ-aminobutyrate-ergic synaptic transmission being the supplier ... Immunochemical studies of brain glutamate decarboxylase and GABA-transaminase of six inbred strains of mice. Brain Res 68:133- ... Nagelhus EA, Ottersen OP (2013) Physiological roles of aquaporin-4 in brain. Physiol Rev 93:1543-1562PubMedCentralPubMedGoogle ... 4.. VanHarreveld A, Crowell J, Malhotra SK (1965) A study of extracellular space in central nervous tissue by freeze- ...
This family consists of L-diaminobutyric acid transaminases. This general designation covers both 2.6.1.76 (diaminobutyrate-2- ... pyruvate transaminase, which uses alanine as the amino donor). Most members with known function are 2.6.1.76, and at least some ... oxoglutarate transaminase, which uses glutamate as the amino donor in DABA biosynthesis), and 2.6.1.46 (diaminobutyrate-- ... also called GABA transaminase. These enzymes all are pyridoxal phosphate-containing class III aminotransferase. ...
Gamma aminobutyric acid transaminase deficiency Synonyms: GABA transaminase deficiency, Gamma aminobutyrate transaminase ... Synonyms: GSD 4, Andersen disease, Brancher deficiency, Amylopectinosis, Glycogen branching enzyme deficiency, Cirrhosis, ... Synonyms: UDP-Galactose-4-epimerase deficiency, GALE deficiency, Galactosemia 3, Epimerase deficiency galactosemia, ... Synonyms: Pompe disease, Acid maltase deficiency disease, Aglucosidase alfa, Alpha-1,4-glucosidase deficiency, Cardiomegalia ...