... untranslated region (3′UTR) of Kamiti River virus (KRV) is nearly twice as long as the 3′UTR of other flaviviruses (1208 ... We also propose that the CFAV 3′UTR was derived from a KRV-like precursor sequence with a large deletion that nevertheless ... However, the construction of a robust comparative nucleotide alignment has now revealed that the double-length 3′UTR and the ... These data provide new insights into the evolution of the flavivirus 3′UTR. ...
... untranslated region of the DMPK gene on chromosome 19 (Aslanidis et al., 1992; Brook et al., 1992; Harley et al., 1992; ... untranslated region of the myotonic dystrophy kinase cDNA inhibits myoblast differentiation in vitro. J. Biol. Chem. 272, 29626 ... 1992). Cloning of the essential myotonic dystrophy region and mapping of the putative defect. Nature 355, 548-551. ... 1992). Expansion of an unstable DNA region and phenotypic variation in myotonic dystrophy. Nature 355, 545-546. ...
... untranslated region of the myotonic dystrophy protein kinase (DMPK) on chromosome 19 (reviewed in [1]). Expansion of the CTG ... Table 3 Lymphocyte, memory B-cell populations, and serology. Full size table. ... 3.. CSL Behring Ltd. Intragam P Product Information. AU PI 1400. 2014. ... Table 3). Serology testing showed protective levels of IgG to diphtheria, Haemophilus influenzae, and tetanus, and low to ...
... untranslated region (3UTR) is emerging as critically important in regulating gene expression at posttranscriptional levels. ... untranslated region in human cancer Cell Oncol. 2007;29(1):1-17. doi: 10.1155/2007/586139. ... untranslated region (3UTR) is emerging as critically important in regulating gene expression at posttranscriptional levels. ...
Untranslated Regions and Fewer MicroRNA Target Sites. By Rickard Sandberg, Joel R. Neilson, Arup Sarma, Phillip A. Sharp, ... Untranslated Regions and Fewer MicroRNA Target Sites. By Rickard Sandberg, Joel R. Neilson, Arup Sarma, Phillip A. Sharp, ... Untranslated Regions and Fewer MicroRNA Target Sites ... Untranslated Regions and Fewer MicroRNA Target Sites. *Rickard ... regulatory regions, possibly because less control is required over RNA functions. ...
... untranslated regions (3 UTRs) and particularly long 3 UTRs have been shown to act as a new class of post-transcriptional ... untranslated regions (3 UTRs) and particularly long 3 UTRs have been shown to act as a new class of post-transcriptional ... Deletion of AU-rich 3 UTRs increased mRNA levels, whereas deletion of 3 UTRs with normal AU content resulted in slight or no ... Deletion of AU-rich 3 UTRs increased mRNA levels, whereas deletion of 3 UTRs with normal AU content resulted in slight or no ...
... untranslated region of mRNA molecules specifying inflammatory mediators. D Caput, B Beutler, K Hartog, R Thayer, S Brown-Shimer ... untranslated region of mRNA molecules specifying inflammatory mediators. D Caput, B Beutler, K Hartog, R Thayer, S Brown-Shimer ... untranslated region of mRNA molecules specifying inflammatory mediators. D Caput, B Beutler, K Hartog, R Thayer, S Brown-Shimer ... untranslated region of mRNA molecules specifying inflammatory mediators Message Subject (Your Name) has sent you a message from ...
... untranslated region. We introduced a 51 nucleotide AT sequence from a human lymphokine gene, GM-CSF, into the 3 untranslated ... untranslated region of GM-CSF mRNA mediates selective mRNA degradation.. Shaw G, Kamen R. ... region of the rabbit beta-globin gene. Our experiments demonstrate that this caused the otherwise stable beta-globin mRNA to ... The mRNAs of transiently expressed genes frequently contain an AU-rich sequence in the 3 ...
... untranslated region of hepatitis C virus RNA genome.. Luo G1.. Author information. 1. Department of Virology, Bristol-Myers ... untranslated region (3 UTR) of the hepatitis C virus RNA genome. Two cellular proteins, with estimated molecular masses of 58 ... an RNA containing the variable region of the 3 UTR with a deletion of both poly(U) tract and 98 nt failed to compete for ... In addition to binding to the conserved 98 nucleotides (nt) of the 3 UTR, p58 also binds to the poly(U) tract of the 3 UTR. ...
... untranslated (3′UTR) regions which are composed of two regions, one region from an 3untranslated region of a stable ... The present invention describes the use of hybrid short 3′ ... untranslated (3′UTR) regions which are composed of two regions ... Eukaryotic messenger RNA (mRNA) contains three regions, 5′ untranslated region (5′UTR), protein coding region, and 3′ ... untranslated region (3′UTR) that comprises a first and a second nucleic acid region, wherein (a) said first region is a 3′ ...
... untranslated region (3-UTR) of KRAS and let-7g, and its association with development of lung cancer in the patients with COPD. ... untranslated region of KRAS compromises its interaction with hsa-let-7g and contributes to the development of lung cancer in ... and that introduction of rs712 minor allele into 3-UTR significantly compromised the miRNA/mRNA interaction by using a ... Our study demonstrated that KRAS 3-UTR rs712 polymorphism interfered with miRNA/mRNA interaction, and showed that the minor ...
... untranslated region: strain-specific polymorphisms and motifs regulating IGF-I in osteoblasts.. [Spenser S Smith, Catherine B ... untranslated region (UTR) is polymorphic between C3H and B6. Luciferase-Igf1 3 UTR reporter constructs showed that these ... The Igf1 coding region is nonpolymorphic, but its 3 ... polymorphic regions did not affect UTR function. IGF-I splice ... The Igf1 3 UTR encoded by exon 6 contains alternative polyadenylation sites. Proximal site use produces a short 3 UTR of ...
... untranslated region (3′-UTR) contains two exclusively linked, polymorphic sites at positions 811 (C/T) and 1125 (G/A), which ... untranslated region of the human Sep15 gene. Cancer Res. 2001;61:2307-10.Google Scholar ... untranslated region of the selenoprotein 15-kDa (Sep15) gene and breast cancer in Caucasian women. ... 3.Department of Blood Group Serology and Transfusion MedicineMedical University of ViennaViennaAustria ...
Untranslated Region Sequencing Resolves Expression of Gene Families Message Subject (Your Name) has sent you a message from ... Untranslated Region Sequencing Resolves Expression of Gene Families. Andrea L. Eveland, Donald R. McCarty, Karen E. Koch ... untranslated region (UTR) of messenger RNAs (mRNAs). Resulting sequences resolve gene-specific transcripts independent of a ... untranslated region (UTR) is rich in single-feature polymorphisms that distinguish closely related transcripts (Bhattramakki et ...
... untranslated region functions as a cis-acting translational repressor.. B L Black, J Lu, E N Olson ... untranslated region functions as a cis-acting translational repressor. Message Subject (Your Name) has forwarded a page to you ... untranslated region (UTR) and fused it to the chloramphenicol acetyltransferase (CAT) reporter gene. Here, we show by CAT assay ... untranslated region functions as a cis-acting translational repressor. ...
Untranslated Region (3′UTR) Induces Organ Adhesion by Regulating miR-199a* Functions. Daniel Y. Lee,1,2 Tatiana Shatseva,1,2 ... untranslated region (3′UTR) of the target mRNAs, leading to translational repression [7]-[9]. By silencing various target mRNAs ... It is expected that there is no endogenous miRNA bind to this fragment as it is in the coding region. The PCR product was then ... 2008;3:e1719. [PMC free article] [PubMed]. 9. Hua Z, Lv Q, Ye W, Wong CK, Cai G, et al. MiRNA-directed regulation of VEGF and ...
... untranslated region in mammalian mRNAs. Shuo Gu,1 Lan Jin,1 Feijie Zhang,1 Peter Sarnow,2 and Mark A. Kay1 ... untranslated regions (3UTR) of mRNAs to down-regulate their expression when the appropriate miRNA is bound to target mRNA. To ... These results show that while miRNA-mediated translational inhibition was limited to targets in the untranslated region, RNAi- ... Duursma AM, Kedde M, Schrier M, le Sage C, Agami R. miR-148 targets human DNMT3b protein coding region. Rna. 2008;14:872-7. [ ...
The Protein Zfand5 Binds and Stabilizes mRNAs with AU-rich Elements in Their 3 prime Untranslated Regions ...
... untranslated region. J Biol Chem 2000; 275, 11750-11757.PubMedCrossRefGoogle Scholar ... Untranslated Region in Cancer Cells. In: Yazici Z., Folco G.C., Drazen J.M., Nigam S., Shimizu T. (eds) Advances in ... This pentamer, frequently located in or near a U rich region, has been associated with the regulation of the stability of a ... 3.Division of Clinical PharmacologyVanderbilt University School of Medicine, The Vanderbilt-Ingram Cancer CenterNashvilleUSA ...
Complementary microRNA profiling revealed that shortened 3 UTRs are enriched for target sites of macrophage-expressed miRNAs, ... with systematic shifts towards increased cassette exon inclusion and shortening of Tandem 3 UTRs post-infection. These ... results therefore provide the first genome-wide empirical support for the idea that actively regulated shifts towards shorter 3 ... Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection ...
Untranslated Region and Mediates Potential 5′-3′-End Cross Talks of Mouse Hepatitis Virus RNA. Peiyong Huang, Michael M. C. Lai ... long untranslated region (3′-UTR) (21). When MHV is passaged at a high multiplicity of infection in cell culture, defective- ... untranslated region of the coronavirus RNA is required for subgenomic mRNA transcription from a defective interfering RNA.J. ... untranslated region (3′-UTR) of mouse hepatitis virus (MHV) RNA regulates the replication of and transcription from the viral ...
... ... untranslated regions (UTR) of a SAV3 isolated from Atlantic salmon in Norway. The sequences of the UTRs are very similar to ... 3-CSE). Prediction of the RNA secondary structure suggested putative stem-loop structures in both the 5- and 3-ends, similar ... those of SAV1 and SAV2, but single nucleotide polymorphisms are present, also in the 3 - conserved sequence element ( ...
We show that many genes have 3UTR regions extending beyond currently known gene regions and provide a method to identify such ... untranslated regions (UTRs) of transcripts are not well characterized for many genes and often extend beyond the annotated ... We verified 8 of the predictions by PCR and found all of the predicted regions to be expressed. The method can be extended to ... These extensions have a similar conservation as known 3UTRs, which is distinctly higher than intergenic regions. ...
... untranslated region. Suzanne MIYAMOTO, John A. CHIORINI, Elena URCELAY, Brian SAFER. Biochemical Journal May 01, 1996, 315 (3) ... These activities might be modulated by sequence elements contained within the untranslated regions of the eIF-2α gene. ... untranslated region (UTR) of eIF-2α, only two of which are normally utilized in human and mouse tissues. A functional role for ... Regulation of gene expression for translation initiation factor eIF-2α: importance of the 3untranslated region ...
... untranslated region, Archives of Virology" on DeepDyve, the largest online rental service for scholarly research with thousands ... "Molecular characterization of a foot-and-mouth disease virus containing a 57-nucleotide insertion in the 3′ ... Genetic adaptation to untranslated region-mediated enterovirus growth deficits by mutations in the nonstructural proteins 3AB ... A region of the 5′ noncoding region of foot-and-mouth disease virus RNA directs efficient internal initiation of protein ...