3-hydroxyanthranilic acid | definition of 3-hydroxyanthranilic acid by Medical dictionary
What is 3-hydroxyanthranilic acid? Meaning of 3-hydroxyanthranilic acid medical term. What does 3-hydroxyanthranilic acid mean? ... Looking for online definition of 3-hydroxyanthranilic acid in the Medical Dictionary? 3-hydroxyanthranilic acid explanation ... and formiminoglutamic acid, were determined by liquid chromatography--tandem mass spectrometry (14-17), and methylmalonic acid ... kynurenic acid, anthranilic acid, 3-hydroxykynurenine, xanthurenic acid, 3-hydroxyanthranilic acid, ...http://medical-dictionary.thefreedictionary.com/3-hydroxyanthranilic+acid
Chapter 7: Role of the kynurenine pathway in immune- mediated infl ammation - Nuffield Department of Orthopaedics, Rheumatology...
... anthranilic acid (a synthetic derivative of 3-hydroxyanthranilic acid) reduced the severity of disease. A more recent study has ... Indoleamine 2,3-dioxygenase (IDO) plays a key role in immune homeostasis via depletion of tryptophan and accumulation of ... anthranilic acid (a synthetic derivative of 3-hydroxyanthranilic acid) reduced the severity of disease. A more recent study has ... Indoleamine 2,3-dioxygenase (IDO) plays a key role in immune homeostasis via depletion of tryptophan and accumulation of ...https://www.ndorms.ox.ac.uk/publications/604845
3-hydroxyanthranilic acid - Substance Information - ECHA
3-hydroxyanthranilic acid. ↓Other names: Regulatory process names  IUPAC names  ...https://echa.europa.eu/fr/substance-information/-/substanceinfo/100.008.148
3-Hydroxyanthranilic acid - Wikipedia
Mechanism of Formation of Quinolinic Acid". Journal of Biological Chemistry. 234 (4): 880-883. PMID 13654282. Retrieved 2015-09 ... 3-Hydroxyanthranilic acid is an intermediate in the metabolism of tryptophan. It is new antioxidant isolated from methanol ... "3-Hydroxyanthranilic acid". Santa Cruz Biotechnology, Inc. Retrieved 2015-09-24. Armarego, Wilfred L.F.; Chai, Christina L.L. ( ... 44 (3): 696. doi:10.1021/jf950454t. HAA concentration graph in lyophilized tempeh powder extract (in Indonesian). ...https://en.wikipedia.org/wiki/3-Hydroxyanthranilic_acid
3-Hydroxyanthranilic acid oxygenase-containing astrocytic processes surround glutamate-containing axon terminals in the rat...
Since quinolinic acid is known to enter the extracellular compartment readily, these results suggest that astrocytic quinolinic ... In order to explore the anatomical basis of possible functional interactions between glutamate and quinolinic acid in the rat ... is the biosynthetic enzyme for quinolinic acid, an endogenous agonist of the NMDA glutamate receptor subtype and a potent ... 3-Hydroxyanthranilic acid oxygenase-containing astrocytic processes surround glutamate-containing axon terminals in the rat ...http://www.jneurosci.org/content/15/2/1150
bmse000321 3-Hydroxyanthranilic Acid at BMRB
A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules Member of ... Benzoic acid, 2-amino-3-hydroxy-; benzoic acid, 2-amino-3-hydroxy-; 2-amino-3-hydroxybenzoic acid; 2-Amino-3-hydroxy-benzoic ... 2-amino-3-hydroxybenzoic acid. PUBCHEM iupac TRADITIONAL NAME: PUBCHEM iupac OPENEYE NAME: PUBCHEM iupac SYSTEMATIC NAME. 2- ... 3-Hydroxyanthranilic Acid bmse000321 - Data 3-Hydroxyanthranilic Acid synonyms. 2-AMINO-3-HYDROXY-BENZOIC ACID; 3-Hydroxy- ...http://bmrb.wisc.edu/metabolomics/mol_summary/?molName=3-Hydroxyanthranilic+acid
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central...
... kynurenic acid; KYNU, kynureninase; QA, quinolinic acid; PIC, picolinic acid; TRP, tryptophan; XA, xanthurenic acid. Bold box ... xanthurenic acid [XA], QA, picolinic acid [PIC], and neopterin were analyzed in CSF and serum by liquid chromatography-tandem ... Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status. Ann ... Valle M, Price RW, Nilsson A, Heyes M, Verotta D. CSF quinolinic acid levels are determined by local HIV infection: cross- ...https://link.springer.com/article/10.1186%2Fs12974-018-1366-3
Aminobenzoates - DrugBank
Flufenamic Acid. Prostaglandin G/H synthase 1. target. DB02266. Flufenamic Acid. Solute carrier family 22 member 6. transporter ... Aminosalicylic Acid. Group IIE secretory phospholipase A2. target. DB00233. Aminosalicylic Acid. Prostaglandin G/H synthase 2. ... Flufenamic Acid. Androgen receptor. target. DB02266. Flufenamic Acid. Peroxisome proliferator-activated receptor alpha. target ... 4-(DIMETHYLAMINO)BENZOIC ACID. Replicase polyprotein 1ab. target. DB08748. 4-(DIMETHYLAMINO)BENZOIC ACID. Orf1a polyprotein. ...https://www.drugbank.ca/categories/DBCAT000585
haao - 3-hydroxyanthranilate 3,4-dioxygenase - Xenopus laevis (African clawed frog) - haao gene & protein
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously ... p>This subsection of the 'Function' section describes the interaction between a single amino acid and another chemical entity. ... p>This subsection of the 'Function' section describes the interaction between a single amino acid and another chemical entity. ... p>This subsection of the 'Function' section describes the interaction between a single amino acid and another chemical entity. ...http://www.uniprot.org/uniprot/Q6P7I0
ANTHRANILIC ACID PRODUCTS
N-(4-Chloro-1-naphthyl)anthranilic acid 51671-14-8. N-(4-Chloro-alpha,alpha,alpha-trifluoro-o-tolyl)anthranilic acid. 51679-39- ... N-((m-Bromophenoxy)acetyl)-5-chloroanthranilic acid. 70796-19-9. N-(1-(Dimethylcarbamoyl)ethyl)anthranilic acid ethyl ester ... 4,5-Dimethoxyanthranilic acid 5653-40-7. 4-Acetamido-5-((2-methoxy-5-((2-(sulphooxy)ethyl)sulphonyl)phenyl)azo)anthranilic acid ... N-(m-Trifluoromethoxyphenyl)anthranilic acid. 51679-40-4. N-(N'-(2-Bromoethyl)carbamoyl)anthranilic acid methyl ester 102583-94 ...http://www.chemicalland21.com/info/ANTHRANILIC%20ACID%20PRODUCTS.htm
BNA1 - 3-hydroxyanthranilate 3,4-dioxygenase - Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage...
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously ... Biosynthesis of nicotinic acid protein 1UniRule annotation. ,p>Manual validated information which has been generated by the ... p>This subsection of the 'Function' section describes the interaction between a single amino acid and another chemical entity. ... p>This subsection of the 'Function' section describes the interaction between a single amino acid and another chemical entity. ...http://www.uniprot.org/uniprot/B2AAJ5
Human Metabolome Database: Showing metabocard for Cinnavalininate (HMDB0004078)
Cinnavalininate, also known as cinnabarinic acid or cinnabarinate, is a member of the class of compounds known as phenoxazines ... InChI=1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21) ... It is generated from 3-hydroxyanthranilate via the enzyme catalase (EC:220.127.116.11)... ...http://www.hmdb.ca/metabolites/HMDB04078
SCOP: Superfamily: RmlC-like cupins
Quercetin 2,3-dioxygenase-like  (2) Share a common two-domain fold with the 7S protein; there is a metal-binding site in ... Pfam 06052; 3-HAO *Acetylacetone-cleaving enzyme-like  (1) PfamB 026844 *VPA0057-like  (1) Pfam 06865; DUF1255 ... Type I phosphomannose isomerase  (3) Share a common two-domain fold with the 7S protein; there is a metal-binding site ... Gentisate 1,2-dioxygenase-like  (3) Share a common two-domain fold with the 7S protein; there is a metal-binding site ...http://scop.mrc-lmb.cam.ac.uk/scop/data/scop.b.c.bdi.b.html
Chemotaxis of Burkholderia sp. Strain SJ98 towards chloronitroaromatic compounds that it can metabolise | BMC Microbiology |...
2-chloro-3-nitrophenol (2C3NP), 4-chloro-2-nitrophenol (4C2NP), 2-chloro-4-nitrobenzoate (2C4NB), 4-chloro-2-nitrobenzoate ( ... glacial acetic acid in methanol and 1% glacial acetic acid in the ratio 80:20 at a constant flow rate of 1.0 ml.min-1 as the ... sulphanilic acid, nitric acid and all the high quality growth media from local vendors. Calibrated capillary tubes (10 μl) used ... 5-dinitrobenzoic acid in aqueous solutions. Environ Toxicol Chem. 2004, 23: 1129-1135. 10.1897/03-73.PubMedView ArticleGoogle ...https://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-2180-12-19
KAKEN - Research Projects | Significance of soluble Fas and its related cytokines in serum of rheumatoid arthritis patients. ...
12(3). 241-247 (2000). *. Description. 「研究成果報告書概要(和文)」より ... Publications] Morita.T: '3-Hydroxyanthranilic acid, AL-Tryptophan metabolite, induces apoptosis in monocyte-derived cell ... Publications] Morita.T: '3-Hydroxyanthranilic acid, AL-Tryptophan metabolite, induces apoptosis in monocyte-derived cell ... Publications] MORITA Toshiko, et al: '3-Hydroxyanthranilic Acid, AL-Tryptophan Metabolite, Induces Apoptosis in Monocyte- ...https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10671352/
Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites | PNAS
1981) Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS. Eur J Pharmacol 72(4):411-412. ... 1984) Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid. ... 1990) Determination of extracellular kynurenic acid in the striatum of unanesthetized rats: Effect of aminooxyacetic acid. ... propionic acids, kynurenic acid, and related metabolites as luminophores and free-radical scavengers. Adv Exp Med Biol 467:389- ...https://www.pnas.org/content/113/19/5435.full
IL-17 and Therapeutic Kynurenines in Pathogenic Inflammation to Fungi | The Journal of Immunology
... an early amino acid catabolite of l-tryptophan in the IDO-dependent pathway (22). These data expand on previous data of ... in which STAT3 as well as retinoic acid receptor-related orphan receptor (ROR)γ and more recently RORα (40) mediate lineage ... 3⇓ and Refs 2 and 3). These observations also suggest that IDO and kynurenines, in their capacity to induce Tregs and inhibit ... FIGURE 3. Metabolic regulation of Th17/Treg lineage decision; the opposing roles of IL-17 and kynurenines. In its ability to ...http://www.jimmunol.org/content/180/8/5157
Göran K Hansson | Profile page | Karolinska Institutet
Retinoic acid inhibits nitric oxide synthase-2 expression through the retinoic acid receptor-alpha. Sirsjo A, Gidlof Ac, Olsson ... Induction of CD36 by all-trans retinoic acid: retinoic acid receptor signaling in the pathogenesis of atherosclerosis. Wuttge ... Conserved amino acid residues in T cell receptros of atherosclerotic lesions in apoE KO mice. Paulsson G, Tornquist E, Hansson ... Retinoic acid regulates arterial smooth muscle cell proliferation and phenotypic features in vivo and in vitro through an RAR ...https://ki.se/en/people/gorhan
Der Stoffwechsel der P-haltigen Verbindungen | Springer for Research & Development
Mitchell, H. K., and J. F. Nyc: Hydroxy-anthranilic acid as a precursor of nicotinic acid in Neurospora. Proc. Nat. Acad. Sci. ... Jono, Y.: Nucleic acid. I. Enzymes which split nucleic acid. Acta Scholae med. Kioto 13:162-175 (1930).Google Scholar ... Kalan, E. B., and P. B. Srinivasan: Synthesis of 5-dehydro-shikimic acid from carbohydrates in a cell-free extract. Amino Acid ... Hardin, M. B.: On the occurrence of meta-phosphoric acid and pyrophosphoric acid in cotton seed meal. S. Carolina Exper. Sta. ...https://rd.springer.com/chapter/10.1007/978-3-662-21766-5_3
3-hydroxyanthranilate 3,4-dioxygenase - Wikipedia
In enzymology, a 3-hydroxyanthranilate 3,4-dioxygenase (EC 18.104.22.168) is an enzyme that catalyzes the chemical reaction 3- ... DECKER RH, KANG HH, LEACH FR, HENDERSON LM (1961). "Purification and properties of 3-hydroxyanthranilic acid oxidase". J. Biol ... The systematic name of this enzyme class is 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing). Other names in ... 3-hydroxyanthranilic acid oxidase, and 3HAO. This enzyme participates in tryptophan metabolism. It employs one cofactor, iron. ...https://en.wikipedia.org/wiki/3-hydroxyanthranilate_3,4-dioxygenase
Biomimetic and bioinspired approaches for wiring enzymes to electrode interfaces - Energy & Environmental Science (RSC...
GO is a graphene sheet with carboxylic acids at its edges and phenol, hydroxyl and epoxide groups along the basal plane.167 GO ... For example, β-gal proteins can have half-lives in vivo from three minutes to over 20 hours depending on their amino acid ... Glucose + O2 → gluconic acid + H2O2. −0.080 V at pH 7.042. ... 64 Formic acid production of 413.8 mg mL−1 was achieved at −1 V ... Tan et al. (2016) recently replaced the phenylalanine and tyrosine amino acids on the carboxyl terminus of Geobacter ...https://pubs.rsc.org/en/content/articlehtml/2017/ee/c6ee02801b
The role of indoleamine 2,3-dioxygenase in LP-BPM5 murine retroviral disease progression
... quinolic acid, and picolinic acid), all of which can contribute to T-cell suppression [8,11,12]. T-helper 1 (Th1) cell clones ... The neurotoxin quinolinic acid is increased in spinal cords of mice with herpes simplex virus encephalitis. Adv Exp Med Biol. ... Grohmann U, Bronte V. Control of immune response by amino acid metabolism. Immunol Rev. 2010;236:243-264. doi: 10.1111/j.1600- ... while picolinic acid is able to induce iNOS in conjunction with IFNγ activation [47,48]. In short, it is becoming appreciated ...http://pubmedcentralcanada.ca/pmcc/articles/PMC3751850/?lang=en-ca
Radical Scavenging Properties of Tryptophan Metabolites | SpringerLink
Goda, K., Kishimoto, R., Shimizu, S., Hamane, Y., and Ueda, M., 1996, Quinolinic acid and active oxygens; possible contribution ... xanthurenic acid, serotonin, N-acetylserotonin) is similar to that of butylated hydroxytoluene (BHT); the third group ( ... kynurenic acid, melatonin, and other ones) is less reactive than BHT.. Keywords. Glutathione Serotonin Disulfide NADPH ... The first group (3-hydroxykynurenine, 3-hydroxyanthranilic acid, and indole-3-pyruvic acid) is more reactive than α-tocopherol ...https://link.springer.com/chapter/10.1007/978-1-4615-4709-9_50
3-hydroxyanthranilate oxidase - Wikipedia
In enzymology, a 3-hydroxyanthranilate oxidase (EC 22.214.171.124) (also called 3-HAO) is an enzyme that catalyzes the chemical ... This enzyme is also called 3-hydroxyanthranilic acid oxidase. Vécsei, L; Szalárdy, L; Fülöp, F; Toldi, J (January 2013). " ... Morgan LR Jr, Weimorts DM, Aubert CC (1965). "Oxidation Of 3-hydroxyanthranilic acid by a soluble liver fraction from ... The systematic name of this enzyme class is 3-hydroxyanthranilate:oxygen oxidoreductase. ...https://en.wikipedia.org/wiki/3-hydroxyanthranilate_oxidase
3-Hydroxyanthranilic acid | CAS 548-93-6 | SCBT - Santa Cruz Biotechnology
Buy 3-Hydroxyanthranilic acid (CAS 548-93-6), a tryptophan metabolite along the kynurenine pathway, from Santa Cruz. Purity: ≥ ... 3-Hydroxyanthranilic acid (CAS 548-93-6) 3-Hydroxyanthranilic acid , CAS 548-93-6 is rated 5.0 out of 5 by 1. ... 3-Hydroxyanthranilic acid (CAS 548-93-6) has the appearance of a Light Pink to Light Brown Solid. Soluble in 1N HCl (10 mg/ml ... 3-Hydroxyanthranilic acid is a tryptophan metabolite along the kynurenine pathway. 3-Hydroxyanthranilic acid has been shown to ...https://www.scbt.com/scbt/product/3-hydroxyanthranilic-acid-548-93-6