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*  Human type 10 17 beta-hydroxysteroid dehydrogenase: molecular modelling and substrate docking.
11 different mammalian 17 beta-hydroxysteroid dehydrogenases have been identified, catalyzing the cell- and steroid-specific ... The structure obtained displays the properties of a one-domain, alpha/beta fold enzyme of the SDR family. The active site is ... The human type 10 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD-10) is a multifunctional mitochondrial enzyme that ... Finally, it is involved in beta-oxidation of fatty acids by catalyzing the L-hydroxyacyl CoA dehydrogenase reaction of the beta ...
https://oacentre.kennedy.ox.ac.uk/publications/108608
*  Most recent papers with the keyword "3 beta-hydroxysteroid dehydrogenase deficiency" | Read by QxMD
The diagnosis was androgen insensitivity in 7 patients, congenital adrenal hyperplasia in 2 due to 17 alpha-hydroxylase ... amplified by polymerase chain reaction using primers specific for the type II gene, in one male pseudohermaphrodite with salt- ... CONCURRENT 3-BETA-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY IN ADRENAL AND SCLEROCYSTIC OVARY.. L R AXELROD, J W GOLDZIEHER, S D ... Steroid 3-beta hydroxysteroid dehydrogenase type II (3β-HSD2) deficiency is a rare autosomal recessive form of congenital ...
https://www.readbyqxmd.com/keyword/109579
*  Targeted integration into stem cells - Patent application
11 beta-hydroxysteroid dehydrogenase, Calretinin, Cyp17 and Cyp11a1, Esterase, Inhibin-alpha, IGF-1 (insulin like growth factor ... Go alpha (alpha subunit of guanine nucleotide-binding protein Go), Keratin 20, NSE (neuron-specific enolase), TROMA-1, Villin ... hydroxysteroid dehydrogenase (3beta-HSD) VI, 17beta-hydroxysteroid dehydrogenase (17beta-HSD) III, vascular cell adhesion ... alpha-galactosidase A, alpha-L-iduronidase, N-acetlygalactosamine 4-sulfatase and acid alpha-glucosidase. In general, suitable ...
http://www.patentsencyclopedia.com/app/20110027235
*  World Hair Research» Blog Archive » Dermal Papilla Androgen Sensitivity, Androgen Receptors & Methylation
3beta-hydroxysteroid dehydrogenases (3b-HSD) and type 1 and 2 5alpha-reductase (type 1 and type 2 5alpha-R). Type 2 5-alpha- ... A 2004 study shed more light on specific processes that shorten the hair cycle (that occur within the DP). According to the ... Some of the known intrafollicular steroidogenic enzymes found in the DP are: Steroid Sulfatase (STS), 17beta-hydroxysteroid ... study, the three processes are as follows: "(1) the conversion of testosterone to DHT by type II 5-alpha-reductase; (2) the ...
http://www.worldhairresearch.com/?p=293
*  Stop Fat Storage
Testosterone stimulates adipose tissue 11beta-hydroxysteroid dehydrogenase type 1 expression in a depot-specific manner in ... Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 ... 11beta-hydroxysteroid dehydrogenase type 1 mRNA is increased in both visceral and subcutaneous adipose tissue of obese patients ... Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 activity in vivo limits glucocorticoid exposure to human adipose ...
https://www.stopfatstorage.com/
*  A.E.Brain: Sexual differentiation of the human brain (2009)
Gender change in 46,XY persons with 5alpha-reductase-2 deficiency and 17beta-hydroxysteroid dehydrogenase-3 deficiency. Arch ... Estrogen receptor-alpha distribution in the human hypothalamus in relation to sex and endocrine status. J Comp Neurol 2002;454: ... Specific cerebral activation due to visual erotic stimuli in male-to female transsexuals compared with male and female controls ... when a boy foetus has a 5a-reductase-2 or 17s-hydroxy-steroid dehydrogenase-3 deficiency preventing peripheral testosterone ...
http://aebrain.blogspot.com/p/sexual-differentiation-of-human-brain.html
*  Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism That Prevents High-Fat Diet...
Generation of β-cell-specific 11β-HSD1 overexpression model.. The rat 11β-HSD1 cDNA was cloned downstream of the mouse insulin ... Role of the CCAAT/enhancer binding protein-alpha transcription factor in the glucocorticoid stimulation of p21waf1/cip1 gene ... Hexose-6-phosphate dehydrogenase knock-out mice lack 11 beta-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid ... Human and rodent type 1 11beta-hydroxysteroid dehydrogenases are 7beta-hydroxycholesterol dehydrogenases involved in oxysterol ...
http://diabetes.diabetesjournals.org/content/61/3/642
*  A metabolomic approach to identifying platinum resistance in ovarian cancer | Journal of Ovarian Research | Full Text
11-beta-hydroxysteroid dehydrogenase type 1; TKTL1: transketolase 1; ATP5G2: ATP synthase; PL1N2: perilipin 2; CA5A: carbonic ... peroxisome proliferator-activated receptor alpha; IDH1: isocitrate dehydrogenase 1; MOGAT2:acyl CoA: monoacylglycerol ... Differential metabolite discovery specific to ovarian cancer. Electrophoresis. 2012;33:3361-9.View ArticlePubMedGoogle Scholar ... succinate dehydrogenase, lactate dehydrogenase; fatty acid oxidation: Carnitine palmitoyltransferase-1, Acetyl CoA Carboxylase ...
https://ovarianresearch.biomedcentral.com/articles/10.1186/s13048-015-0140-8
*  Evaluating histological modifications of testis and spermatogenesis in adult male rats on finasteride
... is a competitive and specific inhibi-tor of type II 5--reductase, an intracellular enzyme that convert... ... hydroxysteroid dehydrogenases: Key enzymes in androgen metabolism. Best Pract Res Clin Endocrinol Metab. 2001;15:79-94. [PubMed ... Enzyme assay for 5 alpha-reductase type 2 activity in the presence of 5 alpha-reductase type 1 activity in rat testis. J ... McLachlan RI, O'Donnell L, Meachem SJ, Stanton tification of specific sites of hormonal regulation in spermatogenesis in rats, ...
http://www.jri.ir/article/274
*  Progestin effects on cell proliferation pathways in the postmenopausal mammary gland | Breast Cancer Research | Full Text
Specific genes induced by CEE + MPA treatment included key members of prolactin receptor (PRLR)/signal transducer and activator ... 17-beta hydroxysteroid dehydrogenase type 1. HSD17B2: 17-beta hydroxysteroid dehydrogenase type 2 ... Specific genes induced by CEE + MPA treatment included key members of prolactin receptor (PRLR)/signal transducer and activator ... Treatment effects on ER activity were not directly associated with changes in expression of ER-alpha (ESR1), ER-beta (ESR2) ( ...
https://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr3456
*  CSIRO PUBLISHING | Reproduction, Fertility and Development
Analysis of aromatase and 17beta-hydroxysteroid dehydrogenase type 2 messenger ribonucleic acid expression in deep ... Xiong, Y., Liu, Y., Xiong, W. Q., Zhang, L., Liu, H. W., Du, Y., and Li, N. (2016). Hypoxia-inducible factor 1 alpha-induced ... Specific reverse transcription-PCR quantification of vascular endothelial growth factor (VEGF) splice variants by LightCycler ... Analysis of aromatase and 17beta-hydroxysteroid dehydrogenase type 2 messenger ribonucleic acid expression in deep ...
http://www.publish.csiro.au/RD/RD17184
*  Complete genome sequence of the sand-sediment actinobacterium Nocardioides dokdonensis FR1436T | Environmental Microbiome |...
Reversed position specific-BLAST. Uniref: UniProt reference clusters. Declarations. Acknowledgements. We recognize Ju Yeon Song ... 2016;198(3):279-85.View ArticlePubMedGoogle Scholar. *. Han JH, Kim TS, Joung Y, Kim MN, Shin KS, Bae T, Kim SB. Nocardioides ... 2016;62(3):643-56.View ArticlePubMedGoogle Scholar. *. Mohn WW, Wilbrink MH, Casabon I, Stewart GR, Liu J, van der Geize R, ... 3 and Table 3). The genome has 4165 genes that are comprised of 4104 CDSs, three rRNA operons, 51 tRNAs, and one tmRNA. Results ...
https://environmentalmicrobiome.biomedcentral.com/articles/10.1186/s40793-017-0257-z
*  Charlene Welch - Page 2 - Help Children through Fitness
In this situation I'll, even though I'm not often inclined to posit guesses on a specific medication does or does not do ... Anadrol is an anabolic steroid, meaning it's been C17-Alpha Alkylated so that you can enable the anabolic steroid without ... It's considered it functions as an oestrogen in specific cells. This mentioned later about and may be further enlarged upon, ... Anadrol's substance alterations and substance framework (including its C17-Alpha Alkylation) causes it to be quite resistant to ...
http://childrensrightscentre.co.za/author/administrator/page/2/
*  The Tsim Tsoum Approaches for Prevention of Cardiovascular Disease
It is possible that transgenic mice overexpressing 11β hydroxysteroid dehydrogenase type 1 (11βHSD-1) selectively in adipose ... Nicotinic acetylecholine receptor alpha-7 subunit is an essential regulator of inflammation. Nature . 2003;421:384-388. [PubMed ... No specific antiinflammatory drugs are available to treat the proinammatory state. However, several drugs used to treat other ... g day−1) mustard oil (120 patients, alpha-linolenic acid 2.9. g day−1), and no treatment (118 patients, placebo group) on the ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2910415/
*  Cytochrome P450 - Wikipedia
Hydroxysteroid dehydrogenase. ... Other specific CYP functionsEdit. Steroid hormonesEdit. ... 7-alpha hydroxylation of 24-hydroxycholesterol. 1 subfamily, 1 gene. CYP39A1 CYP46. cholesterol 24-hydroxylase. 1 subfamily, 1 ... The specific problem is: broken links; fragmented paragraph. Please help improve this section if you can. (September 2016) ( ... steroid biosynthesis, 17-alpha hydroxylase. 1 subfamily, 1 gene. CYP17A1 CYP19. steroid biosynthesis: aromatase synthesizes ...
https://en.m.wikipedia.org/wiki/P450
*  KEGG SSDB Paralog Search Result: bdi:100824427
bdi:100839980 11-beta-hydroxysteroid dehydrogenase-like K22418 451 105 ( -) 30 0.408 49 -, bdi:104585171 SH3 domain-binding ... bdi:100821815 probable alpha,alpha-trehalose-phosphate K16055 851 100 ( -) 29 0.432 74 -, bdi:100825997 acidic leucine-rich ... bdi:104584776 pollen-specific leucine-rich repeat exten 544 104 ( -) 30 0.321 84 -, bdi:100827175 zinc finger protein 8-like ... bdi:100832963 alpha carbonic anhydrase 8 224 115 ( -) 32 0.302 96 -, bdi:100837376 lipoamide acyltransferase component of br ...
http://www.kegg.jp/ssdb-bin/ssdb_paralog?org_gene=bdi:100824427
*  US20080292618A1 - Intranuclear protein transduction through a nucleoside salvage pathway - Google Patents
For example, to treat low testosterone levels, a gene or gene product of 17β hydroxysteroid dehydrogenase, 3β hydroxysteroid ... C07K2317/00-Immunoglobulins specific features * C07K2317/80-Immunoglobulins specific features remaining in the (producing) cell ... IL-7R alpha-chain mutations may be treated with IL7R alpha, CD3 delta or epsilon mutations may be treated with CD3 delta or ... C07K2317/00-Immunoglobulins specific features * C07K2317/60-Immunoglobulins specific features characterized by non-natural ...
https://patents.google.com/patent/US20080292618A1/en
*  KEGG SSDB Best Search Result: cfa:487523
baph:IX46_01255 DNA polymerase III subunit alpha K02337 1155 100 ( -) 29 0.306 62 ,-, 1 bcl:ABC2632 glutamyl-tRNA reductase ... csq:CSCA_0253 anaerobic dehydrogenase 681 106 ( -) 30 0.323 99 ,-, 1 dpd:Deipe_1236 D-xylulose kinase K00854 497 106 ( -) 30 ... etr:ETAE_0124 site-specific recombinase XerC K03733 303 103 ( -) 29 0.309 191 ,-, 1 fox:FOXG_22259 hypothetical protein 200 103 ... syr:SynRCC307_2336 Alpha-glycosidase of family GH38 K01191 971 100 ( -) 29 0.365 63 -, 1 taz:TREAZ_1113 glycoside hydrolase ...
http://www.kegg.jp/ssdb-bin/ssdb_best?org_gene=cfa:487523
*  CAIRO LIVER DEVELOPMENT DN
dehydrogenase/reductase (SDR family.... 1426547_at. 2638. GC. group-specific component (vitamin D.... ... collagen, type XVIII, alpha 1. 1418239_at. 319. APOF. apolipoprotein F. 1418267_at. 4485. MST1. macrophage stimulating 1 ( ... hydroxysteroid (17-beta) dehydrogen.... 1418365_at. 1512. CTSH. cathepsin H. 1418405_at. 3083. HGFAC. HGF activator. ... show 3 datasets) E-MEXP-1851, E-MEXP-1852, E-MEXP-1853 ... acyl-CoA dehydrogenase, C-4 to C-12.... 1416025_at. 2266. FGG. ...
http://software.broadinstitute.org/gsea/msigdb/cards/CAIRO_LIVER_DEVELOPMENT_DN.html
*  Grapefruit (Citrus paradisi) | Plant Profiler | Sigma-Aldrich
In vivo study has found that the dietary flavonoids in grapefruit juice may inhibit the enzyme 11β-hydroxysteroid dehydrogenase ... It has been suggested that phenolic compounds can be used as biomarkers of specific poly-phenol rich food, in particular, ... In human liver microsomes, the mean IC50 for grapefruit juice versus CYP3A (triazolam alpha-hydroxylation) was 0.55%, without ... Grapefruit juice and its flavonoids inhibit 11 beta-hydroxysteroid dehydrogenase. Clin Pharmacol Ther 1996;59(1):62-71. 8549035 ...
https://www.sigmaaldrich.com/life-science/nutrition-research/learning-center/plant-profiler/citrus-paradisi.html
*  ARTICLES | Physiological Genomics
Motojima K. 17beta-hydroxysteroid dehydrogenase type 11 is a major peroxisome proliferator-activated receptor alpha-regulated ... We first analyzed in detail the expression of PPARα throughout the small intestine and then evaluated the outcome of specific ... Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha). Carcinogenesis ... Mandard S, Muller M, Kersten S. Peroxisome proliferator-activated receptor alpha target genes. Cell Mol Life Sci 61: 393-416., ...
http://physiolgenomics.physiology.org/content/30/2/192?ijkey=84a3b6e30c76231506da2781fef5cd9c10c30519&keytype2=tf_ipsecsha
*  Unusual Endocrine Dermatoses in the Dog and Cat - WSAVA2008 - VIN
Alpha-tocopheryl. Oestrogen-receptor blockers--although a regulatory oestrogen receptor pathway for telogen-anagen hair ... Trilostane--inhibits 3β-hydroxysteroid dehydrogenase. Normally given at a dose rate of 3-4 mg/kg per day PO for several months ... Melatonin--administered normally at an initial dose of 3-6 mg twice daily (bodyweight can be a factor). Based on clinical ...
https://www.vin.com/apputil/content/defaultadv1.aspx?pId=11268&meta=Generic&catId=32718&id=3866609&ind=51&objTypeID=17
*  cwocbd, Author at All About CBD Oil - Page 3 of 92
... or 17-beta-hydroxysteroid dehydrogenase deficiency (17beta-HSD-3).. Rabbits do not fall into that strange and rare category of ... It is a specific state of the body, which is characterized by an elevated level of ketones in the blood, which occurs due to ... In fact there are even more rare cases of humans that have changed gender as a result of either 5-alpha-reductase deficiency ( ... Specific foods to avoid include colored drinks, color-coated candies, gummy and chewy candies, and many colored cereals. ...
http://www.allaboutcbdoil.com/author/cwocbd/page/3/
*  Structural studies of transcriptional regulators - Mitchell Lewis
We will determine how alternate sequences can interact with specific bases using an in vivo assay. The diversity in the ... we have created directed libraries of repressor molecules by randomizing the residues making specific interactions with bases ... 1994) Three-dimensional structure of rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase: a member of the aldo-keto ...
http://grantome.com/grant/NIH/R01-GM044617-18
*  Microbial Functional Responses to Cholesterol Catabolism in Denitrifying Sludge | mSystems
Ten transcripts were annotated as bifunctional beta-hydroxysteroid dehydrogenase/isomerase AcmA. Additionally, up to 81 ... side chain-specific molybdoenzyme C25 dehydrogenase, and several β-oxidation enzymes. Another Mo-containing 1-testosterone ... C) Alpha subunit of C25DH and its homologues. Subunits (A1 to A4) displaying specificity for side chain substrates are ... aldehyde dehydrogenase; Δ4R, ketosteroid-Δ4-reductase; DH, dehydrogenase; AtcABC, 1-testosterone dehydrogenase/hydratase. ...
https://msystems.asm.org/content/3/5/e00113-18