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*  The role of indoleamine 2,3-dioxygenase in LP-BPM5 murine retroviral disease progression
... quinolic acid, and picolinic acid), all of which can contribute to T-cell suppression [8,11,12]. T-helper 1 (Th1) cell clones ... The neurotoxin quinolinic acid is increased in spinal cords of mice with herpes simplex virus encephalitis. Adv Exp Med Biol. ... Grohmann U, Bronte V. Control of immune response by amino acid metabolism. Immunol Rev. 2010;236:243-264. doi: 10.1111/j.1600- ... while picolinic acid is able to induce iNOS in conjunction with IFNγ activation [47,48]. In short, it is becoming appreciated ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC3751850/?lang=en-ca
*  Metabolomic changes in autopsy confirmed Alzheimer's disease
The selected model uses tryptophan, norepinephrine, and indoleacetic acid, with AIC=8. This model offers complete separation on ... Linear predictor of AD status from logistic regression on tryptophan, norepinephrine, and indoleacetic acid. Circles=non- ... acetic acid at −2 0 ° C and vortexed for 45-60sec, then temperature was brought to −15 ° C in a cold block, and vortexed again ... and indoleacetic acid, offered complete separation of the groups. MHPG is a major NE metabolite and ratios of MHPG/NE are 4 ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC3061205/?lang=en-ca