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*  20alpha-hydroxysteroid dehydrogenase - Wikipedia
20alpha-dihydroxypregn-4-en-3-one, NAD+, and NADP+, whereas its 4 products are 17-alpha-hydroxyprogesterone, NADH, NADPH, and ... Other names in common use include 20alpha-hydroxy steroid dehydrogenase, 20alpha-hydroxy steroid dehydrogenase, 20alpha-HSD, ... "Expression of 17beta-hydroxysteroid dehydrogenase type 1 and type 2, P450 aromatase, and 20alpha-hydroxysteroid dehydrogenase ... Hershkovitz L, Beuschlein F, Klammer S, Krup M, Weinstein Y (March 2007). "Adrenal 20alpha-hydroxysteroid dehydrogenase in the ...
https://en.wikipedia.org/wiki/20alpha-hydroxysteroid_dehydrogenase
*  3beta(or 20alpha)-hydroxysteroid dehydrogenase - Wikipedia
... hydroxysteroid dehydrogenase (EC 1.1.1.210) is an enzyme that catalyzes the chemical reaction 5α-androstan-3β,17β-diol + NADP+ ... H+ This enzyme possesses the combined activities of the 3-β-hydroxysteroid dehydrogenase/Δ-5-4 isomerase and 20-α- ... hydroxysteroid dehydrogenase enzymes. Sharaf MA, Sweet F (September 1982). "Dual activity at an enzyme active site: 3 beta,20 ... alpha-hydroxysteroid oxidoreductase from fetal blood". Biochemistry. 21 (19): 4615-20. doi:10.1021/bi00262a016. PMID 6958329. ...
https://en.wikipedia.org/wiki/3beta(or_20alpha)-hydroxysteroid_dehydrogenase
*  Regulation of T cell differentiation: in vitro induction of 20 alpha-hydroxysteroid dehydrogenase in splenic lymphocytes from...
In vitro, 20 alpha SDH can be induced in splenic lymphocytes from nu/nu mice by conditioned media from mitogen- or alloantigen- ... The enzyme 20 alpha-hydroxysteroid dehydrogenase (20 alpha SDH) has previously been shown to be a specific enzyme marker of ... In vivo, the expression of 20 alpha SDH is thymus dependent, in that splenic lymphocytes from athymic mice have only low levels ... The factor responsible for 20 alpha SDH induction has been partially purified and is distinct from other known lymphokines in ...
https://www.jimmunol.org/content/126/6/2184
*  Changes in Ovarian and Placental 20α-hydroxysteroid Dehydrogenase Activity during the Pregnancy in the Rat | Korea Science
... alpha}$-HSD Activity;Progesterone;$20{\alpha}$-dihydroprogesterone;Rat Ovary; ... Changes in Ovarian and Placental 20α-hydroxysteroid Dehydrogenase Activity during the Pregnancy in the Rat - $20{\ ... alpha}$. -hydroxysteroid dehydrogenase activity in spontaneous Neoplasms in the dog and cat. J. Vet. Med. Sci. 53:549-552. ... alpha}$. -hydroxysteroid dehydro-genase in the control of progesterone synthesis preceding parturition and lactogenesis in the ...
http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=E1DMBP_2003_v16n3_342
*  KEGG BRITE: KEGG Orthology (KO) - Mus musculus (mouse)
... corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-] K05295 E1.1.1.149; 20alpha-hydroxysteroid dehydrogenase [EC:1.1. ... 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22] K12345 SRD5A3; 3-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.1.22 1.3. ... dehydrogenase 1 15486 Hsd17b2; hydroxysteroid (17-beta) dehydrogenase 2 27400 Hsd17b6; hydroxysteroid (17-beta) dehydrogenase 6 ... 15483 Hsd11b1; hydroxysteroid 11-beta dehydrogenase 1 15484 Hsd11b2; hydroxysteroid 11-beta dehydrogenase 2 105349 Akr1c18; ...
http://www.genome.jp/kegg-bin/get_htext?mmu00001+394435
*  HSD17B1 antibody [EP1682Y] Recombinant (ab51045) | Abcam
Hydroxysteroid (17 beta) dehydrogenase 1 antibody. *MGC13814 antibody. *Placental 17 beta hydroxysteroid dehydrogenase antibody ... Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. ... PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific ...
http://www.abcam.com/hsd17b1-antibody-ep1682y-ab51045.html
*  AKR1C4 Gene - GeneCards | AK1C4 Protein | AK1C4 Antibody
Chlordecone Reductase; 3-Alpha Hydroxysteroid Dehydrogenase, Type I; Dihydrodiol Dehydrogenase 4 2 3 ... Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes. (PMID: 10672042) ... aldo-keto reductase family 1,member C4 (3-alpha hydroxysteroid dehydrogenase,type I),with high affinity for dihydrotestosterone ... Molecular cloning of two human liver 3 alpha- hydroxysteroid/dihydrodiol dehydrogenase isoenzymes that are identical with ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=AKR1C4
*  AKR1C4 gene - Genetics Home Reference - NIH
5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The ...
https://ghr.nlm.nih.gov/gene/AKR1C4
*  Recombinant human HSD3a protein (ab109831) | Abcam
3 alpha HSD1. *3-alpha-HSD1. *3-alpha-hydroxysteroid dehydrogenase type I ... 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The ... Store at -20°C or -80°C. Avoid freeze / thaw cycle.. Preservative: None. Constituents: 20% Glycerol, 0.58% Sodium chloride, ...
https://www.abcam.com/recombinant-human-hsd3a-protein-ab109831.html
*  Frasor J[au] - PubMed - NCBI
Response-specific and ligand dose-dependent modulation of estrogen receptor (ER) alpha activity by ERbeta in the uterus. ... Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells. ... Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) alpha or ERbeta in human ... 20.. PHLDA1 expression is controlled by an estrogen receptor-NFκB-miR-181 regulatory loop and is essential for formation of ER+ ...
https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Frasor+J%5Bau%5D&dispmax=50
*  KAKEN - Research Projects | Development of new in vivo systems for the evaluation of growth factors function. (KAKENHI-PROJECT...
... hydroxysteroid dehydrogenase.' Biochemca et Biophysica Acta. 1079. 112-118 (1991). *. Description. 「研究成果報告書概要(欧文)」より ... Growth Factors / Cytokine / Activin / Transforming Growth Factor-beta / Nerve growth factor / Tumor Necrosis Factor-alpha / ... hydroxysteroid dehydrogenase in luteotrophic and luteolytic processes during rat pseudopregnancy.' Journal of Reproduction and ... and alpha- subunits in the early embryos and oviducts of different strains of mice.' Journal of Reproduction and Development.38 ...
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01860040/
*  Human Metabolome Database: Showing metabocard for 3a,7a-Dihydroxy-5b-cholestane (HMDB0006893)
... the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity. Gene ... 2. Alcohol dehydrogenase 1A. General function:. Involved in zinc ion binding. Specific function:. Not Available. Gene Name:. ... 3alpha-hydroxy steroid (CHEBI:28047 ). *7alpha-hydroxy steroid (CHEBI:28047 ). *C27 bile acids, alcohols, and derivatives ( ... 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The ...
http://www.hmdb.ca/metabolites/HMDB0006893
*  Human Metabolome Database: Showing metabocard for Etiocholanedione (HMDB0003769)
The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as ... 2. 3-oxo-5-beta-steroid 4-dehydrogenase. General function:. Involved in oxidoreductase activity. Specific function:. ... 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The ... Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta- ...
http://www.hmdb.ca/metabolites/HMDB0003769
*  Albarracin CT[au] - PubMed - NCBI
Isocitrate dehydrogenase 1 R132H mutation is not detected in angiocentric glioma.. Raghunathan A, Olar A, Vogel H, Parker JR, ... Identification of a major prolactin-regulated protein as 20 alpha-hydroxysteroid dehydrogenase: coordinate regulation of its ... Isolation and characterization of a rat luteal cDNA encoding 20 alpha-hydroxysteroid dehydrogenase. ...
https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Albarracin+CT%5Bau%5D&dispmax=50
*  GO Gene List
Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II). NM_003739. NM_001253908. NM_001253909 ... Aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid ... 3-alpha)-hydroxysteroid dehydrogenase). NM_001353. Gene Info. AKR1C2. ... Filamin A, alpha. NM_001110556. NM_001456. Gene Info. FLT1. Fms-related tyrosine kinase 1 (vascular endothelial growth factor/ ...
https://cgap.nci.nih.gov/Genes/GoGeneQuery?PAGE=1&ORG=Hs&GOID=0023056
*  Cloxazolam - Wikipedia
... alpha-hydroxysteroid dehydrogenase for neurosteroids and its inhibition by benzodiazepines" (pdf). Biol Pharm Bull. 25 (4): 441 ... Usami N; Yamamoto T; Shintani S; Ishikura S; Higaki Y; Katagiri Y; Hara A. (Apr 2002). "Substrate specificity of human 3(20) ...
https://en.wikipedia.org/wiki/Cloxazolam
*  Recombinant Human AKR1C1, His-tagged AKR1C1-27157TH - Creative BioMart
3-alpha)-hydroxysteroid dehydrogenase); DDH1; aldo-keto reductase family 1 member C1; DD1; DDH; HAKRC; MBAB;. ... 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; aldo-keto reductase (NADP) activity; androsterone ... AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase ... AKR1C1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha ( ...
https://www.creativebiomart.net/description_61505_7.htm
*  AKR1C1 Pre-design Chimera RNAi - (H00001645-R01) - Products - Abnova
3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1), mRNA. (H00001645-R01) - Products - Abnova ... dihydrodiol dehydrogenase 1,dihydrodiol dehydrogenase isoform DD1,hepatic dihydrodiol dehydrogenase,trans- ... 2-ALPHA-HSD,20-ALPHA-HSD,C9,DD1,DDH,DDH1,H-37,HAKRC,MBAB,MGC8954 ... Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ... Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid ...
http://www.abnova.com/products/products_detail.asp?catalog_id=H00001645-R01
*  ENZYME entry 1.1.1.149
17-alpha,20-alpha-dihydroxypregn-4-en-3-one + NAD(P)(+) <=> 17-alpha-hydroxyprogesterone + NAD(P)H. ...
https://enzyme.expasy.org/EC/1.1.1.149
*  Efficacy and Safety Assessment of T2345 in Ocular Hypertensive or Glaucomatous Patients
... prostaglandin F2-alpha (FP receptors), and prostacyclin (IP receptors). ... Aldo-keto reductase that functions as a bi-directional 17 BETA, 20 ALPHA-HYDROXYSTEROID DEHYDROGENASE. It catalyzes the ...
https://www.bioportfolio.com/resources/trial/63209/Efficacy-and-Safety-Assessment-of-T2345-in-Ocular-Hypertensive-or-Glaucomatous-Patients.html
*  GO Gene List
3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4). NM_001818. Gene Info. ... Alcohol dehydrogenase 1A (class I), alpha polypeptide. NM_000667. Gene Info. ADH1B. Alcohol dehydrogenase 1B (class I), beta ... Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II). NM_003739. NM_001253908. NM_001253909 ... Aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid ...
https://cgap.nci.nih.gov/Genes/GoGeneQuery?PAGE=1&ORG=Hs&GOID=0070887
*  Mechanisms in Interleukin 3 Regulated Growth and Differentiation | SpringerLink
Regulation of T cell differentiation: In vitro induction of 20 alpha hydroxysteroid dehydrogenase in splenic lymphocytes is ... Interleukin 2 and 3 regulate the in vitro proliferation of two distinguishable populations of 20 alpha hydroxysteroid ... dehydrogenase positive cells. J. Immunol. 135:1864, (1985).Google Scholar. *. 13.. J. N. Ihle, J. Keller, A. Rein, J. Cleveland ...
https://link.springer.com/chapter/10.1007/978-1-4684-5323-2_15
*  High Expression of 17β-hydroxysteroid Dehydrogenase Type 2 is Associated with a Better Prognosis in Urothelial Carcinoma of the...
protein kinase; AMP-activated; alpha 1 catalytic subunit. ATP binding, cAMP-dependent protein kinase activity, kinase activity ... Keywords: 17β-hydroxysteroid dehydrogenase type 2, Urothelial carcinoma, Prognosis. Introduction. The enzyme 17β-hydroxysteroid ... hydroxysteroid (17-beta) dehydrogenase 2. estradiol 17-beta-dehydrogenase activity, oxidoreductase activity. ... 17Beta-hydroxysteroid dehydrogenase Type 1 and Type 2: association between mRNA expression and activity in cell lines. Mol Cell ...
http://www.jcancer.org/v07p2221.htm
*  Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis | Science
S8C). This phenotype matches that of IRA B cells (18-20). The remaining, non-B IL-3-positive cells in the spleen and thymus ... Regulation of T cell differentiation: In vitro induction of 20 alpha-hydroxysteroid dehydrogenase in splenic lymphocytes from ...
https://science.sciencemag.org/content/347/6227/1260
*  Plus it
The SNP rs11648233 resides in the 17-beta-hydroxysteroid dehydrogenase II gene (HSD17B2), which functions in the pathway that ... Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 ... alpha-hydroxysteroid dehydrogenase activity. J Biol Chem 1993;268:12964-9. ... of 20% and a per-allele effect size of 1.5 based on a genome-wide significance level of P = 5.0 × 10−8 (ref. 47; Fig. 3A, pink ...
http://cancerdiscovery.aacrjournals.org/content/4/2/155