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*  Adenosine receptor modulation of seizure susceptibility in rats
2-ClAdo-induced elevation of BIC seizure threshold was not antagonized by the benzodiazepine antagonists RO 15-1788 and CGS ... The rank order of potency for adenosine agonists to elevate PTZ seizure threshold was R-PIA , 2-ClAdo , NECA , CHA , S-PIA. R- ... This anticonvulsant action of 2-ClAdo and the proconvulsant effect of theophylline were observed with other chemoconvulsants ... The anticonvulsant action of 2-ClAdo was reversed by pretreatment with theophylline. Theophylline alone produced a ...
https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/s7526g99n