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*  On-column ligand exchange for structure-based drug design: a case study with human 11[beta]-hydroxysteroid dehydrogenase type 1...
2013-11-15. OSTI Identifier:. 1090101. Resource Type:. Journal Article. Resource Relation:. Journal Name: Acta Crystallogr. F; ... Journal Article: On-column ligand exchange for structure-based drug design: a case study with human 11[beta]-hydroxysteroid ... Title: On-column ligand exchange for structure-based drug design: a case study with human 11[beta]-hydroxysteroid dehydrogenase ...
https://www.osti.gov/scitech/biblio/1090101-column-ligand-exchange-structure-based-drug-design-case-study-human-beta-hydroxysteroid-dehydrogenase-type
*  3 beta hydroxysteroid dehydrogenase deficiency (Symptoms, signs, causes, treatments & definition) - Medigest
Medigest has all you need to know about 3 beta hydroxysteroid dehydrogenase deficiency - Symptoms and Signs, Causes, Treatments ... Looking for information on 3 beta hydroxysteroid dehydrogenase deficiency? ... 3 beta hydroxysteroid dehydrogenase deficiency Below you will find more information about 3 beta hydroxysteroid dehydrogenase ... Discuss 3 beta hydroxysteroid dehydrogenase deficiency in our forums Discuss 3 beta hydroxysteroid dehydrogenase deficiency ...
https://www.medigest.uk/diseases/3-beta-hydroxysteroid-dehydrogenase-deficiency/
*  What does 11-beta-hydroxysteroid dehydrogenases stand for?
Beta' is one option -- get in to view more @ The Web's largest and most authoritative acronyms and abbreviations resource. ... Looking for the definition of 11-beta-hydroxysteroid dehydrogenases? Find out what is the full meaning of 11-beta- ... Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. ... What does 11-beta-hydroxysteroid dehydrogenases mean? This page is about the various possible meanings of the acronym, ...
http://www.abbreviations.com/serp.php?st=11-beta-hydroxysteroid%20dehydrogenases&qtype=3
*  Corticosteroid 11 Beta Dehydrogenase Isozyme 1 (11 Beta Hydroxysteroid Dehydrogenase 1 or Short Chain Dehydrogenase/Reductase...
Corticosteroid 11 Beta Dehydrogenase Isozyme 1 (11 Beta Hydroxysteroid Dehydrogenase 1 or Short Chain Dehydrogenase/Reductase ... 11beta-hydroxysteroid dehydrogenase type 1 is an NADPH-dependent enzyme highly expressed in key metabolic tissues including ... Corticosteroid 11 Beta Dehydrogenase Isozyme 1 (11 Beta Hydroxysteroid Dehydrogenase 1 or Short Chain Dehydrogenase/Reductase ... Corticosteroid 11 Beta Dehydrogenase Isozyme 1 (11 Beta Hydroxysteroid Dehydrogenase 1 or Short Chain Dehydrogenase/Reductase ...
https://www.marketresearch.com/Global-Markets-Direct-v3480/Corticosteroid-Beta-Dehydrogenase-Isozyme-Hydroxysteroid-11955495/
*  HSD11b2 recombinant protein | 11-Beta-Hydroxysteroid Dehydrogenase Type 2 Recombinant Protein-AAC50356.1
11-Beta-Hydroxysteroid Dehydrogenase Type 2 Recombinant Protein-AAC50356.1 (MBS2031421) product datasheet at MyBioSource, ... Belongs to the short-chain dehydrogenases/reductases (SDR) family.. Protein type: Oxidoreductase; Lipid Metabolism - C21- ... HSD11b2 recombinant protein :: 11-Beta-Hydroxysteroid Dehydrogenase Type 2 Recombinant Protein. Catalog #. MBS2031421 (SPECIAL ... 11 publications with HSD11b2 and Inflammation. Renal Insufficiency Antibodies. >9 publications with HSD11b2 and Renal ...
https://www.mybiosource.com/hsd11b2-recombinant-protein/11-beta-hydroxysteroid-dehydrogenase-type-2/2031421
*  Research programme: 11-beta hydroxysteroid dehydrogenase type 1 inhibitors - Poxel - AdisInsight
... is developing 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors for the ... Mechanism of Action 11-beta hydroxysteroid dehydrogenase type 1 inhibitors * Orphan Drug Status Orphan designation is assigned ... Research programme: 11-beta hydroxysteroid dehydrogenase type 1 inhibitors - Poxel Alternative Names: 11 beta HSD1 inhibitor - ... 21 Oct 2016 11-beta hydroxysteroid dehydrogenase type 1 inhibitors are still in Early research phase for Type-2 diabetes ...
https://adisinsight.springer.com/drugs/800032548?error=cookies_not_supported&code=480e00d9-928e-41cc-abbe-2c66721cc61d
*  11-Beta-Hydroxysteroid Dehydrogenase Type 1 (Hsd11b1) Antibody -Abbexa
11-Beta-Hydroxysteroid Dehydrogenase Type 1 (Hsd11b1) Antibody 由Abbexa供应,该产品简介:11-Beta-Hydroxysteroid Dehydrogenase Type 1 ( ... 产品名称:11-Beta-Hydroxysteroid Dehydrogenase Type 1 (Hsd11b1) Antibody ...
http://abbexa.bioleaf.com/Product_2061238823.html
*  Human 11-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD11b3) ELISA Kit - ELISA Kits - Products
Human 11-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD11b3) ELISA Kit 96 Tests $809.00 add to cart ... Human 11-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD11b3) ELISA Kit 96 Tests $809.00 add to cart ... This assay has high sensitivity and excellent specificity for detection of 11-Beta-Hydroxysteroid Dehydrogenase Type 3 ... No significant cross-reactivity or interference between 11-Beta-Hydroxysteroid Dehydrogenase Type 3 and analogues was observed ...
https://www.biomatik.com/products/elisa-kits/human-11-beta-hydroxysteroid-dehydrogenase-type-3-hsd11b3-elisa-kit.html
*  Hsd11b2 MGI Mouse Gene Detail - MGI:104720 - hydroxysteroid 11-beta dehydrogenase 2
J:29215 Cole TJ, Cloning of the mouse 11 beta-hydroxysteroid dehydrogenase type 2 gene: tissue specific expression and ...
http://www.informatics.jax.org/marker/MGI:104720
*  HSD17B11 hydroxysteroid 17-beta dehydrogenase 11 [Homo sapiens (human)] - Gene - NCBI
Role for 17-beta-HSDXI in androgen metabolism during steroidogenesis. Title: 17 beta-hydroxysteroid dehydrogenase type XI ... 17-beta-hydroxysteroid dehydrogenase type XI. CTCL tumor antigen HD-CL-03. CTCL-associated antigen HD-CL-03. cutaneous T-cell ... 17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs. ... hydroxysteroid 17-beta dehydrogenase 11provided by HGNC. Primary source. HGNC:HGNC:22960 See related. Ensembl:ENSG00000198189 ...
https://www.ncbi.nlm.nih.gov/gene/51170
*  11 beta hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess | 11β-Hydroxysteroid dehydrogenase...
Their findings showed that the D-bifunctional protein plays an essential role in the peroxisomal beta-oxidation pathway that ... Biochemical analysis showed that the 3-hydroxyacyl-CoA dehydrogenase activity of the D-bifunctional protein was completely ... 11 beta hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess. Media:. ... 11 beta hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess. In 2 unrelated patients, Ulick et ...
http://oiu.steroids-australia.net/11-beta-hydroxysteroid-dehydrogenase-and-the-syndrome-of-apparent-mineralocorticoid-excess.html
*  5 alpha-reductase and 11 beta-hydroxysteroid dehydrogenase activity in prepubertal Hispanic girls with premature adrenarche. -...
We studied C19 and C21 urinary steroid metabolites, 5 alpha/5 beta and 11 oxo/11 hydroxy metabolite pairs as well as the ratios ... of the total 5 alpha/total 5 beta and total 11 oxo/total 11 hydroxy metabolites in 24-h urine samples from 17 prepubertal ... We found no differences in the 5 alpha-reductase or 11 beta-hydroxysteroid dehydrogenase activities in the prepubertal girls ... Therefore, in this group of young girls, alterations in 5 alpha-reductase or 11 beta-hydroxysteroid dehydrogenase activities do ...
https://www.semanticscholar.org/paper/5-alpha-reductase-and-11-beta-hydroxysteroid-dehyd-Silfen-Shackleton/018ab3c0f96b12a4e7dcaa84e3ff157db6899159
*  KEE316Hu | ELISA kit for Homo sapiens (Human) 11-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD11b3) | Homo sapiens (Human) |...
Short chain dehydrogenase/reductase family 26C member 2 , Products for research use only! ... Short chain dehydrogenase/reductase family 26C member 2. * 96T (KEE316Hu) US$ 770 ... Elisa Kits › ELISA kit for Homo sapiens (Human) 11-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD11b3) ELISA kit for Homo ... The concentration of 11-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD11b3) in the samples is then determined by comparing the O ...
http://sinoprot.com/products/KEE316Hu
*  Tissue-specific dysregulation of 11 beta-hydroxysteroid dehydrogenase type 1 and pathogenesis of the metabolic syndrome |...
Elevenbeta-hydroxysteroid dehydrogenase type 1 (11beta-HSD-1), a key intracellular enzyme which catalyses the conversion of ... If confirmed, these results would prompt the development of selective and tissue-specific 11beta-HSD-1 inhibitors to decrease ... 11β-hydroxysteroid dehydrogenase type 1; Cortisol; Cortisone; Metabolic syndrome. Settore Scientifico Disciplinare: Settore MED ... studies are less convincing with several case control and cross-sectional studies showing an association between with 11beta- ...
https://air.unimi.it/handle/2434/200905
*  Hsd17b11 MGI Mouse Gene Detail - MGI:2149821 - hydroxysteroid (17-beta) dehydrogenase 11
View mouse Hsd17b11 Chr5:103989765-104021796 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression
http://www.informatics.jax.org/marker/MGI:2149821
*  Hydroxysteroid Dehydrogenase, 11-beta Type II peptide
Buy Hydroxysteroid Dehydrogenase, 11-beta Type II peptide (MBS653968) product datasheet at MyBioSource, Peptides. Application: ... Hydroxysteroid Dehydrogenase, 11-beta Type II, Peptide. ★Popular Item★ Also Known As Hydroxysteroid Dehydrogenase, 11-beta Type ... Hydroxysteroid Dehydrogenase, 11-beta Type II. LOG IN MY ACCOUNT CART CONTENTS CHECKOUT ... Small volumes of Hydroxysteroid Dehydrogenase, 11-beta Type II peptide vial(s) may occasionally become entrapped in the seal of ...
https://www.mybiosource.com/prods/Peptide/Hydroxysteroid-Dehydrogenase-11-beta-Type-II/datasheet.php?products_id=653968
*  Associations between a polymorphism in the hydroxysteroid (11-beta) dehydrogenase 1 gene, neuroticism and postpartum depression
Authority records BETA Iliadis, Stavros I.Comasco, ErikaHellgren, CharlotteSundström Poromaa, IngerSkalkidou, Alkistis Search ... BACKGROUND: This study examined the association between a single nucleotide polymorphism in the hydroxysteroid (11-beta) ... dehydrogenase 1 gene and neuroticism, as well as the possible mediatory role of neuroticism in the association between the ... Available from: 2016-12-02 Created: 2016-12-02 Last updated: 2017-11-29Bibliographically approved ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:1051512
*  hydroxysteroid 11-beta dehydrogenase 1 | 1.-.-.- Oxidoreductases | IUPHAR/BPS Guide to PHARMACOLOGY
hydroxysteroid 11-beta dehydrogenase 1 - 1.-.-.- Oxidoreductases. Detailed annotation on the structure, function, physiology, ... 2009) Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model. J. Med. Chem. ... 1.-.-.- Oxidoreductases: hydroxysteroid 11-beta dehydrogenase 1. Last modified on 12/12/2018. Accessed on 19/04/2019. IUPHAR/ ... 2006) Adamantane 11-beta-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction. Bioorg. Med. Chem. Lett., 16 ( ...
http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2763
*  11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle.
Within skeletal muscle, 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) converts cortisone (11-dehydrocorticosterone ... 11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle.. ... 11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle. 2009, 58 (11 ... 11beta-Hydroxysteroid dehydrogenase type 1 regulates insulin and glucagon secretion in pancreatic islets. ...
https://www.lenus.ie/handle/10147/254113
*  11beta hydroxysteroid dehydrogenase type 2 | A non-isotopic method for estimating 11 beta.
... has both dehydrogenase (11 beta DH) and reductase (11 beta R) activities, which catalyse the interconversion of cortisol and ... 11beta hydroxysteroid dehydrogenase type 2. 11 beta-hydroxysteroid dehydrogenase (11 beta HSD) has both dehydrogenase (11 beta ... Using radiolabelled cortisol 11 beta HSD activity has been shown to be lower in some cases of essential hypertension. This ... This approach was evaluated by inducing partial deficiency of 11 beta HSD in the volunteers who took liquorice (to inhibit 11 ...
http://amc.stoynev.us/11beta-hydroxysteroid-dehydrogenase-type-2.html
*  Type 1 11beta-hydroxysteroid dehydrogenase as universal drug target in metabolic diseases?
The latter effect is accomplished by two different 11beta-hydroxysteroid dehydrogenase isozymes, constituting a shuttle system ... Importantly, 11beta-HSD1 activity appears to be intrinsically linked to all features of the metabolic syndrome, which could at ... Whereas the type 1 enzyme (11beta-HSD1) is in vitro a NADP(H)- dependent bidirectional enzyme, it reduces in most instances in ... The recent development of specific 11beta-HSD1 inhibitors coupled with advances on structural knowledge and regulation of the ...
https://oacentre.kennedy.ox.ac.uk/publications/108459
*  11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle. - Radcliffe...
Within skeletal muscle, 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) converts cortisone (11-dehydrocorticosterone ... A1 (selective 11beta-HSD1 inhibitor) abolished enzyme activity and blocked the increase in pSer(307) IRS1 and reduction in ... Selective 11beta-HSD1 inhibition decreases pSer(307) IRS1, increases pThr(308) Akt/PKB, and decreases lipogenic and lipolytic ... In C57Bl6/J mice, the selective 11beta-HSD1 inhibitor, A2, decreased fasting blood glucose levels and improved insulin ...
https://www.rdm.ox.ac.uk/publications/482083
*  High-level production and optimization of monodispersity of 11beta-hydroxysteroid dehydrogenase type 1.
Heterologous production of 11beta-HSD1, devoid of its N-terminal transmembrane segment, is possible but yields only small ... Here we show that the soluble portion of recombinant 11beta-HSD1 produced in E. coli is found mainly as multimeric aggregates ... Moreover, active site titration of human 11beta-HSD1 revealed that at least 75% of the protein in a typical preparation ... By co-overexpressing GroEL/ES and adding an 11beta-HSD1 inhibitor during protein synthesis, we have increased the accumulation ...
https://oacentre.kennedy.ox.ac.uk/publications/108418
*  Benzothiazole derivatives as novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. - Department of Pharmacology
The benzothiazole derivatives 1 and 2 showed greater than 80% inhibition for 11beta-HSD1 at 10 microM and exhibited IC50 values ... Docking studies with the benzothiazole derivative 1 into the crystal structure of human 11beta-HSD1 revealed how the molecule ... 11beta-HSD1) have considerable potential as treatments for metabolic diseases, such as diabetes mellitus type 2 or obesity. ... the discovery and synthesis of a series of novel benzothiazole derivatives and their inhibitory activities against 11beta-HSD1 ...
https://pharm.ox.ac.uk/publications/640377