HSD11b2 recombinant protein | 11-Beta-Hydroxysteroid Dehydrogenase Type 2 Recombinant Protein-AAC50356.1
11-Beta-Hydroxysteroid Dehydrogenase Type 2 Recombinant Protein-AAC50356.1 (MBS2031421) product datasheet at MyBioSource, ... Belongs to the short-chain dehydrogenases/reductases (SDR) family.. Protein type: Oxidoreductase; Lipid Metabolism - C21- ... The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues ... The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) ...https://www.mybiosource.com/hsd11b2-recombinant-protein/11-beta-hydroxysteroid-dehydrogenase-type-2/2031421
11beta hydroxysteroid dehydrogenase type 2 | A non-isotopic method for estimating 11 beta.
... has both dehydrogenase (11 beta DH) and reductase (11 beta R) activities, which catalyse the interconversion of cortisol and ... 11beta hydroxysteroid dehydrogenase type 2. 11 beta-hydroxysteroid dehydrogenase (11 beta HSD) has both dehydrogenase (11 beta ... Using radiolabelled cortisol 11 beta HSD activity has been shown to be lower in some cases of essential hypertension. This ... This approach was evaluated by inducing partial deficiency of 11 beta HSD in the volunteers who took liquorice (to inhibit 11 ...http://amc.stoynev.us/11beta-hydroxysteroid-dehydrogenase-type-2.html
Organotins disrupt the 11beta-hydroxysteroid dehydrogenase type 2-dependent local inactivation of glucocorticoids. Environ ... Arsenic induces pancreatic beta-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic ... type" and "brain-type" glucose transporters in mice. Mol Pharmacol 1995;47:65-73. ... Testosterone Replacement in Hypogonadal Men With Type 2 Diabetes and/or Metabolic Syndrome (the TIMES2 Study). Diabetes Care ...http://diabetes.diabetesjournals.org/content/60/7/1838
Glucocorticoid excess and the developmental origins of disease: two decades of testing the hypothesis--2012 Curt Richter Award...
Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2012-09-19. ... 0/Glucocorticoids; EC 22.214.171.124/11-beta-Hydroxysteroid Dehydrogenase Type 2 From MEDLINE®/PubMed®, a database of the U.S. ... 11-beta-Hydroxysteroid Dehydrogenase Type 2 / antagonists & inhibitors, physiology. Adaptation, Physiological. Adult. Animals. ... CZB/4/582//Chief Scientist Office; CZG/2/478//Chief Scientist Office; //Wellcome Trust ...http://www.biomedsearch.com/nih/Glucocorticoid-excess-developmental-origins-disease/22998948.html
Regulation of 11β-Hydroxysteroid Dehydrogenase Type 2 by MicroRNANovelty and Significance | Hypertension
Structural analysis of the 11beta-hydroxysteroid dehydrogenase type 2 gene in end-stage renal disease. Kidney Int. 2000;58:1413 ... Molecular basis of human salt sensitivity: the role of the 11beta-hydroxysteroid dehydrogenase type 2. J Clin Endocrinol Metab ... Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2. J Clin Invest. 1999;103:683-689. ... In vivo footprinting of the human 11beta-hydroxysteroid dehydrogenase type 2 promoter: evidence for cell-specific regulation by ...http://hyper.ahajournals.org/content/64/4/860
마더세이프라운드 임옥룡 cs2 0406 - English
... peroxides osteocalcin bone isoenzyme of alkaline phosphatase ascorbic acid IGF-1 IGFBP-3 beta-carotene ... 2. Contents 1. 서론 4. 태아에 대한 영향 2. 병리과정 5. 금연 3. 산모에 대한 영향 6. 결론 ... 11. enzymatic activity 병리과정 • Tobacco usage alter mitochondrial respiratory function in cardiomyocytes and lung tissue. • ... By contrast, most placental zinc remains unbound to MTs • MT-2 isoform(induced by smoking ) could be involved in placental ...https://www.slideshare.net/mothersafe/cs20406
Frontiers | Prenatal stress, glucocorticoids and the programming of adult disease | Behavioral Neuroscience
Reduced placental 11β-HSD2 in human pregnancy correlates with lower birth weight and higher blood pressure in later life. ... Reduced placental 11β-HSD2 in human pregnancy correlates with lower birth weight and higher blood pressure in later life. ... Similarly, in animal models, inhibition or knockout of placental 11β-HSD2 lowers offspring birth weight, in part by reducing ... Similarly, in animal models, inhibition or knockout of placental 11β-HSD2 lowers offspring birth weight, in part by reducing ...https://www.frontiersin.org/articles/10.3389/neuro.08.019.2009/full
The maternal endocrine environment in the low-protein model of intra-uterine growth restriction | British Journal of Nutrition ...
Many adult diseases, including type 2 diabetes, hypertension and cardiovascular disease, are related to low birth weight. The ... 2, 42-46.. Herrera, E, Lasuncion, MA, Gomes Coronado, D, Aranda, P, Lopez-Luna, P & Maier, I (1988) Role of lipoprotein lipase ... Semin Perinatol 2, 223-234.. Ozanne, SE, Martensz, ND, Petry, CJ, Loizou, CL & Hales, CN (1998) Maternal low protein diet in ... Cells Tissues Organs 164, 2-13.. Kaijser, M, Granath, F, Jacosen, G, Cnattingius, S & Ekbom, A (2000) Maternal pregnancy ...https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/maternal-endocrine-environment-in-the-lowprotein-model-of-intrauterine-growth-restriction/26356BAA0DAFEF38379C6E02FD720FD2
A review of the serotonin transporter and prenatal cortisol in the development of autism spectrum disorders | SpringerLink
Chrousos GP: Is 11beta-hydroxysteroid dehydrogenase type 1 a good therapeutic target for blockade of glucocorticoid actions?. ... Delaunay F, Khan A, Cintra A, Davani B, Ling ZC, Andersson A, Ostenson CG, Gustafsson J, Efendic S, Okret S: Pancreatic beta ... Murphy VE, Zakar T, Smith R, Giles WB, Gibson PG, Clifton VL: Reduced 11beta-hydroxysteroid dehydrogenase type 2 activity is ... Cai TQ, Wong B, Mundt SS, Thieringer R, Wright SD, Hermanowski-Vosatka A: Induction of 11beta-hydroxysteroid dehydrogenase type ...https://link.springer.com/article/10.1186/2040-2392-4-37
NAVER Academic > Search...
11 Beta-hydroxysteroid dehydrogenase type 2 in the postnatal and adult rat brain.. 1998 A C Robson et al. Molecular Brain ... 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine, administration & dosage, pharmacology, Animals, Brain, Corpus ... 11-beta-Hydroxysteroid Dehydrogenases, Aging, physiology, Animals, Animals, Newborn, metabolism, Brain, enzymology, growth & ... Unilateral labyrinthectomy downregulates glutamate receptor delta-2 expression in the rat vestibulocerebellum.. 1998 T Kitahara ...https://academic.naver.com/search.naver?field=3&query=Molecular+Brain+Research+61%EA%B6%8C+1-2%ED%98%B8
Classical pathway of steroidogenesis, including diseases (Homo sapiens) - WikiPathways
Cortisone-reductase deficiency associated with heterozygous mutations in 11beta-hydroxysteroid dehydrogenase type 1.''; Proc ... 17-beta-HSD3. Progesterone. 5-alpha-Reductase2. 3-beta-HSD. P450c11. P450c17. P450c17. 3-beta-HSD. Cholesterol side-chain ... 5-alpha-reductase type II deficiency. 9. Aromatase deficiency. 19. 22. P450 oxidoreductase deficiency. 3-beta-HSD type II ... due to 17Î²-hydroxysteroid dehydrogenase type 3 deficiency.''; J Steroid Biochem Mol Biol, 2017 PubMed Europe PMC*Pang S, Wang ...https://www.wikipathways.org/index.php?title=Pathway:WP4523&oldid=103290
HSD2 neurons - Wikipedia
497 (2): 223-50. doi:10.1002/cne.20993. PMID 16705681. Shin, JW; Geerling, JC; Loewy, AD (Dec 10, 2008). "Inputs to the ... 26 (2): 411-7. doi:10.1523/JNEUROSCI.3115-05.2006. PMID 16407537. Geerling, JC; Loewy, AD (Oct 18, 2006). "Aldosterone- ... 93 (2): 177-209. doi:10.1113/expphysiol.2007.039891. PMID 17981930. Geerling, JC; Loewy, AD (Mar 2007). "Sodium depletion ... A small number of HSD2 neurons (less than 2%) may express the neuropeptide galanin. Their lack of expression of the ...https://en.wikipedia.org/wiki/HSD2_neurons
Lesia Kurlak - The University of Nottingham
EFFECT OF NURSING POSITION ON INCIDENCE, TYPE, AND DURATION OF CLINICALLY SIGNIFICANT APNEA IN PRETERM INFANTS ARCHIVES OF ... Maternal nutrient restriction during early to mid-gestation and 11 beta hydroxysteroid dehydrogenase type 2 (11 HSD2) activity ...http://www.nottingham.ac.uk/research/groups/obstetricsgynaecology/people/lesia.kurlak
Environmental Epigenetic Changes, as Risk Factors for the Development of Diseases in Children: A Systematic Review
aOnly in GSTM1 (Glutathione-S-transferase type M1)-present children. bMethylation changes were reverted over time. cAt birth. d ... HISTH4 L (Histone H4 family member). PAX9 (Paired box 9). APBB3 (Amyloid beta precursor protein binding family B member 3). ... and the corticosteroid dehydrogenase isozyme (HSD11B2)  genes. Complementarily, a genome-wide scale study performed in 36 ... hydroxysteroid 11-beta dehydrogenase b2, a gene related to fetal growth) was negatively associated with air PM exposure during ...https://www.annalsofglobalhealth.org/articles/10.29024/aogh.909/
Corticosteroid 11-beta-dehydrogenase isozyme 2 - Wikipedia
2005). "11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response". Endocr. Rev. 25 (5 ... Persu A (2005). "11beta-Hydroxysteroid deshydrogenase: a multi-faceted enzyme". J. Hypertens. 23 (1): 29-31. doi:10.1097/ ... "Entrez Gene: HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2". Geerling, Joel C.; Arthur D. Loewy (September 2009). " ... 1998). "Molecular basis for hypertension in the "type II variant" of apparent mineralocorticoid excess". Am. J. Hum. Genet. 63 ...https://en.wikipedia.org/wiki/Corticosteroid_11-beta-dehydrogenase_isozyme_2
Котелевцев Ю.В. - Лаборатория «Модификация генома стволовых клеток»
11beta-hydroxysteroid dehydrogenase-1 plays a key role in hypothalamo-pituitary arenal axis regulation.. Holmes, M. C., Harris ... Endothelial cell dysfunction in mice after transgenic knockout of type 2, but not type 1, 11 beta-hydromysteroid dehydrogenase ... 56, 2, p. 414-420 7 p.. Hypertension in mice lacking 11 beta-hydroxysteroid dehydrogenase type 2. Kotelevtsev, Y., Brown, R. W ... 25, 2, p. 583-587 5 p.. 1996. Cloning and production of antisera to human placental 11 beta-hydroxysteroid dehydrogenase type 2 ...http://www.p220.ru/home/projects/item/318-11-g34-31-0032
Human Disease Ontology - apparent mineralocorticoid excess - Classes | NCBO BioPortal
cortisol 11-beta-ketoreductase deficiency. 11-beta-hydroxysteroid dehydrogenase deficiency type 2 ...http://bioportal.bioontology.org/ontologies/DOID?p=classes&conceptid=DOID%3A0090121
Maternal Licorice Consumption During Pregnancy and Pubertal, Cognitive, and Psychiatric Outcomes in Children<...
BETA-HYDROXYSTEROID DEHYDROGENASE, ADRENOCORTICAL AXIS FUNCTION, 11-BETA-HYDROXYSTEROID DEHYDROGENASE, GLUCOCORTICOID EXPOSURE ... TYPE-2, 3123 Gynaecology and paediatrics, 3124 Neurology and psychiatry, 515 Psychology", ... keywords = "ADHD, 11 beta-hydroxysteroid dehydrogenase type 2, cognition, glucocorticoids, glycyrrhizin, puberty, ...https://researchportal.helsinki.fi/fi/publications/maternal-licorice-consumption-during-pregnancy-and-pubertal-cogni
Hsd11b2 MGI Mouse Gene Detail - MGI:104720 - hydroxysteroid 11-beta dehydrogenase 2
Blue cells = expressed in wild-type.. Gray triangles = other expression annotations only. (e.g. absence of expression or data ... Survivors are subject to sudden unexplained deaths when between 2 and 4 months of age. They are hypertensive with dilute urine ... 1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;2 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus. ... J:29215 Cole TJ, Cloning of the mouse 11 beta-hydroxysteroid dehydrogenase type 2 gene: tissue specific expression and ...http://www.informatics.jax.org/marker/MGI:104720
Maternal Prenatal Positive Affect, Depressive and Anxiety Symptoms and Birth Outcomes: The PREDO Study
... and Type I diabetes were derived from patient case records and verified by a clinical jury. For the community-based subsample ... gestational and Type I diabetes, antidepressant and other psychotropic medication, and social support (Model 2). In case of ... gestational and Type I diabetes, antidepressant and other psychotropic medication, and social support) explained 8.7% of the ... 2. Ding XX, Wu YL, Xu SJ, Zhu RP, Jia XM, Zhang SF, et al. Maternal anxiety during pregnancy and adverse birth outcomes: a ...https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0150058
Aldosterone-sensitive NTS neurons are inhibited by saline ingestion during chronic mineralocorticoid treatment. - Semantic...
After 7 days of treatment with deoxycorticosterone (2 mg/day), an increased number of HSD2 neurons became immunoreactive for ... contains a unique subpopulation of neurons that express the enzyme 11-beta-hydroxysteroid dehydrogenase type 2 (HSD2). These ... The nucleus of the solitary tract (NTS) contains a unique subpopulation of neurons that express the enzyme 11-beta- ... hydroxysteroid dehydrogenase type 2 (HSD2). These neurons are mineralocorticoid-sensitive and are activated in association with ...https://www.semanticscholar.org/paper/Aldosterone-sensitive-NTS-neurons-are-inhibited-by-Geerling-Loewy/f670e32bd572741a6f2f584a66534000b6db3214
Glucocorticoids produce whole body insulin resistance with changes in cardiac metabolism | Endocrinology and Metabolism
Tomlinson JW, Sinha B, Bujalska I, Hewison M, Stewart PM. Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose ... beta-hydroxysteroid dehydrogenase isoforms using reverse-transcriptase-polymerase chain reaction and localization of the type 2 ... Livingstone DE, Walker BR. Is 11beta-hydroxysteroid dehydrogenase type 1 a therapeutic target? Effects of carbenoxolone in lean ... Seckl JR, Walker BR. Minireview: 11beta-hydroxysteroid dehydrogenase type 1-a tissue-specific amplifier of glucocorticoid ...http://ajpendo.physiology.org/content/292/3/E654.full
HSD11B2 Antibody (Center) - Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) WB, IHC-P, FC, E - Buy Now! |Abgent
The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues ... IgG F(ab')2. IgG F(c). IgG F(ab). IgM. IgA. IgG1. IgG2b. Transferrin. IgG2a. IgG3. IgG2c. ... The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) ... HSD11 type II, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, 11-beta-HSD, HSD11B2, HSD11K. ...http://www.abgent.com/products/AP9764c-HSD11B2-Antibody-Center
Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages |...
Wild-type littermates were used as controls for Zfp521−/− mice. Either Osx-Cre+; Zfp521+/+ or hOC-Cre+; Zfp521+/+ littermates ... Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell. 17:9-26. doi:10.1016/j.devcel.2009.06.016. ... wt, wild type; Δexon4, position of the residual mRNA after removal of exon 4. (D) Genotyping PCR showing deletion of Zfp521 ... 8 A). Similarly, Ebf1−/− calvarial cells exhibited impaired support of OC-genesis from wild-type BM, demonstrating a role for ...http://jem.rupress.org/content/210/5/969
KAKEN - Research Projects | An importance on bone marrow-derived cells on lung repair (KAKENHI-PROJECT-13670589)
... beta]]-Hydroxysteroid dehydrogenase type 2 in BEAS-2B cells.'Am.J.Respir.Crit.Care Med.. 167. 1244-1249 (2003). *. Related ... Recently, many studies suggested that bone marrow cells have the potential to differentiate into a variety of cell types. ...https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13670589/