This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl ... and lysophosphatidic acid-acyltransferase. This enzyme participates in 3 metabolic pathways: glycerolipid metabolism, ... 2-acylglycerophosphate acyltransferase and 1-acylglycerophosphorylcholine acyltransferase from rat-liver microsomes". Eur. J. ... In enzymology, a 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) is an enzyme that catalyzes the chemical reaction ...
... lysophosphatidic acid acyltransferase, epsilon). LPAAT-epsilon. lysophosphatidic acid acyltransferase epsilon. NP_081068.1. *EC ... enables acyltransferase activity IBA Inferred from Biological aspect of Ancestor. more info ... acts_upstream_of_or_within acylglycerol metabolic process IDA Inferred from Direct Assay. more info ... LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like. pfam16076. ...
SLC4 harbors a membrane bound O-acyl transferase (MBOAT) motif, and down regulation of SLC4 strongly reduces 1-acyl-sn-glycerol ... Indeed, affinity-purified Slc1p displays Mg²⁺-dependent acyltransferase activity not only towards lyso-phosphatidic acid but ... SLC1 and SLC4 encode partially redundant acyl-Coenzyme A 1-acylglycerol-3-phosphate O-acyltransferases of budding yeast. * ... Thus, Slc1p and Slc4p may not only be active as 1-acylglycerol-3-phosphate O-acyltransferases, but also be involved in fatty ...
1] In 1959, Seip described a similar congenital syndrome, but without diabetes mellitus, in 3 young Norwegian children. Two of ... Over the next 3 years, a complete generalized loss of subcutaneous fat developed that began focally in the lower extremities. ... The 3 patients exhibited rapid growth with advanced bone age, dilation of the cerebral ventricles, hepatosplenomegaly with ... Related articles include Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Acanthosis Nigricans, Dermatologic Manifestations ...
1-acylglycerol-3-phosphate O-acyltransferase activity. Associated Genes. Gene Name Gene ID Description ...
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ABHD5: abhydrolase domain containing 5, lysophosphatidic acid acyltransferase. *ABL1: ABL proto-oncogene 1, non-receptor ... AGPS: alkylglycerone phosphate synthase. *AGT: angiotensinogen. *AGTR1: angiotensin II receptor type 1 ... ADAMTS2: ADAM metallopeptidase with thrombospondin type 1 motif 2. *ADAMTS10: ADAM metallopeptidase with thrombospondin type 1 ...
... and accumulation of triosephosphates and fructose-6-phosphate (7-9). There is an associated activation of protein kinase C (PKC ... Data are means ± SD (n = 3, except n = 6 for transketolase activity). *P , 0.05, **P , 0.01, and ***P , 0.001 with respect to N ... Data are means ± SD (n = 3, except n = 6 for transketolase activity). *P , 0.05, **P , 0.01, and ***P , 0.001 with respect to N ... Incubation of HMEC-1 cells with these inhibitors for 24 h decreased cell viability by 40-50% and masked the effect of rotenone. ...
Volume 77, Number 1, 2020. Pages 1-14. Review. Jieun Kim*, Yujeong Lee*, Seulah Lee, Kipom Kim, Minjung Song, Jaewon Lee *These ... Volumes 1-78. Volume 79. Volume 80. Volume 81. Volume 82. Volume 83. Volume 84. Volume 85. Volume 86. Volume 87. Volume 88. ... Finally, HSV-1 DNA has been confirmed as present in human brains and is associated with APOE ε4 in AD. HSV-1 and APOE ε4 ... Conclusion: 1) CSF AβR is the CSF amyloid marker that shows the better level of agreement with Amy-PET results; 2) The use of ...
The final step in TG synthesis is the addition of a fatty acyl-CoA to DAG by DAG acyltransferase (DGAT). Another important ... AGPAT, acylglycerol-3-phosphate acyltransferase; PAP, PA phosphohydrolase.. IMTG, fatty acid intermediates, and insulin action. ... DAG acyltransferase; GPAT, glycerol-3-phosphate acyltransferase; HFD, high-fat diet; IKK, IκB kinase; IMTG, intramuscular TG; ... Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers. Proc. Natl. Acad. Sci. U. S. A. 104:7809-7814. View ...
Results: Only CSN2 genotypes A(1)/A(2) were found to have significant association with the SCS (p ... 3, where SCC is the somatic cell count. Polymorphisms in the casein alpha S1 (CSN1S1), beta-casein (CSN2), kappa-casein (CSN3 ... and 1-acylglycerol-3-phosphate O-acyltransferase 6 (AGPAT6) genes were genotyped, and association analysis to the SCS in the ... beta-lactoglobulin (LGB), acyl-CoA diacylglycerol transferase 1 (DGAT1), leptin (LEP), fatty acid synthase (FASN), stearoyl CoA ...
acyl-CoA:2-acylglycerol O-acyltransferase R03756 2,3-Dehydroacyl-CoA + 1-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol. 2,3- ... dehydroacyl-CoA:2-acylglycerol O-acyltransferase R02250 Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid. ... 2-diacyl-sn-glycerol O-acyltransferase R09944 CTP + 1,2-Diacyl-sn-glycerol <=> CDP + Phosphatidate. CTP:1,2-diacyl-sn-glycerol ... 2-diacyl-sn-glycerol O-acyltransferase R02239 Phosphatidate + H2O <=> 1,2-Diacyl-sn-glycerol + Orthophosphate. 1,2-diacyl-sn- ...
If you have used this database, please ensure that you acknowledge this most recent Pseudomonas Genome Database publication rather than just the website URL. Thank you!. Winsor GL, Griffiths EJ, Lo R, Dhillon BK, Shay JA, Brinkman FS (2016 ...
2-Cyclic-Inositol-Phosphate Phosphodiesterase use Glycerophosphoinositol Inositolphosphodiesterase. 1,2-Dibromoethane use ... O-Acyltransferase. 1-Acylglycerophosphocholine Acyltransferase use 1-Acylglycerophosphocholine O-Acyltransferase ... 1-Sar-8-Ile Angiotensin II use 1-Sarcosine-8-Isoleucine Angiotensin II ... 3-Keto-5-alpha-Steroid delta-4-Dehydrogenase use Testosterone 5-alpha-Reductase ...
2-Cyclic-Inositol-Phosphate Phosphodiesterase use Glycerophosphoinositol Inositolphosphodiesterase. 1,2-Dibromoethane use ... O-Acyltransferase. 1-Acylglycerophosphocholine Acyltransferase use 1-Acylglycerophosphocholine O-Acyltransferase ... 1-Sar-8-Ile Angiotensin II use 1-Sarcosine-8-Isoleucine Angiotensin II ... 3-Keto-5-alpha-Steroid delta-4-Dehydrogenase use Testosterone 5-alpha-Reductase ...
2-Cyclic-Inositol-Phosphate Phosphodiesterase use Glycerophosphoinositol Inositolphosphodiesterase. 1,2-Dibromoethane use ... O-Acyltransferase. 1-Acylglycerophosphocholine Acyltransferase use 1-Acylglycerophosphocholine O-Acyltransferase ... 1-Sar-8-Ile Angiotensin II use 1-Sarcosine-8-Isoleucine Angiotensin II ... 3-Keto-5-alpha-Steroid delta-4-Dehydrogenase use Testosterone 5-alpha-Reductase ...
2-Cyclic-Inositol-Phosphate Phosphodiesterase use Glycerophosphoinositol Inositolphosphodiesterase. 1,2-Dibromoethane use ... O-Acyltransferase. 1-Acylglycerophosphocholine Acyltransferase use 1-Acylglycerophosphocholine O-Acyltransferase ... 1-Sar-8-Ile Angiotensin II use 1-Sarcosine-8-Isoleucine Angiotensin II ... 3-Keto-5-alpha-Steroid delta-4-Dehydrogenase use Testosterone 5-alpha-Reductase ...
2-Cyclic-Inositol-Phosphate Phosphodiesterase use Glycerophosphoinositol Inositolphosphodiesterase. 1,2-Dibromoethane use ... O-Acyltransferase. 1-Acylglycerophosphocholine Acyltransferase use 1-Acylglycerophosphocholine O-Acyltransferase ... 1-Sar-8-Ile Angiotensin II use 1-Sarcosine-8-Isoleucine Angiotensin II ... 3-Keto-5-alpha-Steroid delta-4-Dehydrogenase use Testosterone 5-alpha-Reductase ...
ABHD5 encodes an acyltransferase required for lipid metabolism. In humans, variants in ABHD5 cause Chanarin-Dorfman syndrome, a ... 3 complete list of authors * Kiener, Sarah,,Wiener, Dominique J,,Hopke, Kaitlin,,Diesel, Alison B,,Jagannathan, Vidhya,,Mauldin ...
lysophosphatidic acid acyltransferase activity. Drugs. No drugs in record. Diseases. No diseases in record ...
Acylglycerol Metabolic Process. *Phosphatidic Acid Biosynthetic Process. *Phospholipid Biosynthetic Process. *CDP- ... cAMP responsive element binding protein 3 like 1. 1-acylglycerol-3-phosphate O-acyltransferase 5. ...
... lysophosphatidic acid acyltransferase, delta). ... PIRSF MGI GO molecular function annotations for PIRSF005233: 1- ... 1-acylglycerol-3-phosphate O-acyltransferase activity. Agpat5. IDA. color key. Other mouse members of PIRSF005233 with no ... 1-acylglycerol-3-phosphate O-acyltransferase 3. MGI:1915512. Agpat4. 1-acylglycerol-3-phosphate O-acyltransferase 4 ( ... acyl-sn-glycerol-3-phosphate acyltransferase. Green arrows indicate "is_a"; Purple arrows indicate "part_of". Graph is also ...
Results: 1 - 4 of 4 records * GT17240 - CSHL Arabidopsis genetrap mutant lines AT1G01610 glycerol-3-phosphate acyltransferase 4 ... 52-1034-1 - RIKEN Arabidopsis Ds transposon mutant lines AT1G24879 AT1G24880 UDP-3-O-acyl N-acetylglycosamine deacetylase ... 15-3178-1 - RIKEN Arabidopsis Ds transposon mutant lines AT1G24880 UDP-3-O-acyl N-acetylglycosamine deacetylase family protein ... AT1G24880 UDP-3-O-acyl N-acetylglycosamine deacetylase family protein; FUNCTIONS IN: UDP-3-O-[3-hydroxymyri.... AT1G24879 ...
ACYLTRANSFERASE AT1G59820. Predicted. Affinity Capture-MS. FSW = 0.1071 Unknown. ... MEKK1 (MAP KINASE KINASE KINASE 1) DNA BINDING / MAP KINASE KINASE KINASE/ KINASE/ KINASE BINDING / PROTEIN BINDING ...
3] Several candidate genes (BSCL1, BSCL2, BSCL3, BSCL4) have been linked with this syndrome, but not all carry mutations in ... Over the next 3 years, a complete generalized loss of subcutaneous fat developed that began focally in the lower extremities. ... The 3 patients exhibited rapid growth with advanced bone age, dilation of the cerebral ventricles, hepatosplenomegaly with ... Glucagon-like Peptide-1 Analogues - An Efficient Therapeutic Option for the Severe Insulin Resistance of Lipodystrophic ...
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the ... Lane 1 : Agpat2 transfected 293T lysate. Lane 2 : Non-transfected 293T lysate. Lysates/proteins at 15 µl per lane.. Developed ... Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw ... Recombinant full length protein within Human Agpat2 aa 1 to the C-terminus. The exact immunogen sequence used to generate this ...
In the event that glucose levels are low, glycerol will be converted to dihydroxyacetone phosphate and will enter glycolysis at ... CGI-58, at least in vitro, also acts as an acyl-CoA-dependent acylglycerol-3-phosphate acyltransferase. Lets dive into ... NADPH from the pentose phosphate pathway is used by enzymes (fatty acid synthase complex) associated with the pathway. The ... Nadph from the pentose phosphate pathway ( including all genes encoding adrenocep-tors and postreceptor regulators figure. And ...
... acylglycerol-3-phosphate O-acyltransferase, acyltransferase family protein, putative acyltransferase ... 1-acyl-sn-glycerol-3-phosphate acyltransferase, 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative, 1-acyl-sn-glycerol-3- ... phosphate acyltransferase domain-containing protein, 1-acyl-sn-glycerol-3-phosphate acyltransferases, 1-acylglycerol-3- ... description?: 1-acyl-sn-glycerol-3-phosphate acyltransferase. descriptions from strain specific annotations: *1-acyl-sn- ...
... phosphate acyltransferase gene AGPAT7. DNA Seq. 16: 386-390. http://dx.doi.org/10.1080/10425170500213712 PMid:16243729 ... Characterization of a human lysophosphatidic acid acyltransferase that is encoded by a gene located in the class III region of ... R. Li, Wang, B., He, C. Q., Yang, Y. Q., Guo, H., Chen, Y., and Du, T. H., "Upregulation of fibroblast growth factor 1 in the ... 2008). Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- ...