TY - JOUR. T1 - Effect of ischemic arrest on left ventricular relaxation, diastolic stiffness and contractility. AU - Schaff, Hartzell V. AU - Flaherty, J. T.. AU - Fredricksen, J. W.. PY - 1977. Y1 - 1977. N2 - The effect of ischemic arrest (IA) on ventricular relaxation and the diastolic pressure-volume (P/V) relationship was studied in 17 isolated, perfused, isovolumic feline hearts. During one hour of IA, nine hearts were maintained at normothermia (NIA) and eight were cooled to 27°C hypothermia (HIA). Maximum dP/dt was used as an index of contractility. P/V curves were inscribed by constant volume infusion into an intraventricular balloon and plotted according to the equation Pd = βe (dVd), where Pd = end diastolic pressure; Vd = end diastolic volume; (stiffnes constant) = slope of in Pvs Vd; and β = InP intercept at Vd = 0. To normalize for initial cavity size, curves were replotted as Pd vs (Vd-Vo)/V0, where Vo = volume at Pd of 10 mm Hg. Left ventricular relaxation was assessed by ...
This study demonstrates a direct association between decreased regional LV function and reduced regional myocardial perfusion reserve in individuals with coronary artery disease risk factors but who are asymptomatic and have no history of heart disease. This relation was most pronounced in the inferior and posterior walls of the left ventricle. The association between perfusion and regional function was presumably weakened by confounding factors that could not be controlled in this population-based study, yet the observed relation was significant. The ability to detect such a subtle relation is attributed to the accuracy of MRI in quantifying both regional LV function and perfusion reserve.. Importantly, there was no relation between MBF and function at rest among MESA participants, whereas a significant association between regional function at rest with perfusion during adenosine induced hyperemia is documented. Therefore, our findings cannot be explained by local physiological mechanisms ...
Background: The REPAIR-AMI trial has demonstrated that intracoronary infusion of bone marrow-derived progenitor cells (BMC) is associated with a larger recovery of left ventricular contractile function after acute myocardial infarction (AMI) compared to placebo. The present exploratory analysis aims to identify clinical and baseline LV functional predictors of the therapeutic benefit of intracoronary BMC infusion.. Methods: Using a double-blind, placebo controlled multicenter trial design, we randomized 204 patients with successfully reperfused acute myocardial infarction to receive intracoronary infusion of bone marrow - derived progenitor cells (BMC, n = 101) or placebo medium (n= 103) into the reperfused infarct artery. Primary end point was improvement of LV ejection fraction after 4 months.. Results: Overall, recovery of global left ventricular ejection fraction was significantly (p = 0.014) greater in the bone marrow-derived progenitor cell infusion group compared to placebo (absolute ...
Yang Shiwei,Zhou Yujie,Nie Xiaomin,et al. INFLUENCE OF ABNORMAL FASTING PLASMA GLUCOSE ON LEFT VENTRICULAR FUNCTION IN OLDER PATIENTS WITH ACUTE MYOCARDIAL INFARCTION[J]. HEART,2011,suppl.3 ...
Quantification of ventricular pump function is fundamental to the practice of cardiology and is required for research into most aspects of cardiac physiology, disease, and therapeutics. Drawing an analogy between the heart and a steam engine, Otto Frank (1) introduced the pressure-volume diagram as a means of characterizing left ventricular properties in the 1890s. Nearly 80 years later, Suga (2) formalized the idea that the relationship between pressure and volume at end systole was relatively independent of loading conditions and that the slope of the curve, called Emax or Ees, was a sensitive measure of contractility. At nearly the same time, several investigators demonstrated how the relationship between pressure and volume at end diastole similarly provided the framework for quantifying passive properties of the myocardium (3,4). In the decades to follow, there was intensive research into the characteristics of the end-systolic pressure-volume relation (ESPVR) and end-diastolic ...
Ltered left ventricular function. This observation might be explained by the finding of Condorelli et al. emphasizing that a mild activation of Akt through
We found that Nrf2 KO mice show an impaired left ventricular diastolic function as assessed by high resolution ultrasound. Accordingly, isolated perfused Nrf2 KO hearts showed an impaired response to β adrenergic stimulation by isoproterenol, while systolic left ventricular function was preserved. Surprisingly, blood pressure in Nrf2 KO mice was significantly decreased, and endothelial function of arterial conductance and coronary resistive vessels was preserved. This is consistent with an increased maximal dilation after vascular occlusion of the arteria iliaca externa, which indicates a fully preserved vascular and endothelial function in these mice. Mice lacking the endothelial nitric oxide synthase (eNOS KO) showed no dilatatory response to shear stress, confirming that flow-mediated-dilation response mainly depends on eNOS-dependent vasodilatory pathways. The circulating NO pool analysed by HPLC and chemiluminescence showed no differences between Nrf2 KO mice and WT littermates. However, ...
Background. Heterogeneity in regional left ventricular function has long been noted in patients with nonischemic dilated cardiomyopathy. Regional variation in wall stress has been proposed as the pathophysiologic mechanism. By correlating regional function with oxidative metabolism, one can test the hypothesis that heterogeneity in wall stress is responsible for heterogeneity in function. We hypothesized that preserved function as a result of more favorable loading conditions would be associated with regional oxidative metabolism that is equal to or lower than that in other regions. ...
Effect of electrical activation site on left ventricular performance in ventricular tachycardia patients with coronary heart disease.: Some patients with ventri
August 6, 2008 - Toshiba America Medical Systems Inc. delivered the first Aplio Artida ultrasound system to Iowa Heart Center in Des Moines. "Being the first to purchase the Aplio Artida is an exciting development for us and our patients," said Dr. Richard Marcus, director of cardiovascular ultrasound laboratory, Iowa Heart Center. "Having first-hand experience with the system, I am pleased with the images it produces. Its enhanced applications, particularly the 4D imaging, will allow our facility to continue to improve the care provided to our patients.". Dr. Marcus said the Iowa Heart Center selected the Aplio Artida for the systems impressive 4D imaging capability and 3D wall motion tracking.. Toshiba said Artidas real-time, multi-planar reformatting capabilities enable physicians to quantify global and regional LV function, including volumetric LV ejection fraction. Arbitrary views of the heart not available in 2D imaging are also obtained that can help with surgical planning.. The Artida ...
A system and method for determining indicators of left ventricular function, and for determining the effectiveness of a cardiac therapy are disclosed. The indicators of left ventricular function can include isovolumetric relaxation time and the negative slope of a V wave obtained from measuring changes in left atrial pressure during diastole. The apparatus may include a catheter comprising an inflatable balloon for insertion into the esophagus of an individual, a compressor device for pressurizing the balloon, and a means for sensing and recording pressure changes on the balloon.
It would be reasonable in a patient with multivessel CAD and a significant reduction in left ventricular (LV) function to presume that his/her cardiac dysfunction is directly related to myocardial ischemia resulting from a decrease in coronary blood flow and coronary flow reserve (CFR). Although all of the following are associated with LV dysfunction, whether the myocardium is stunned, hibernating, or infarcted depends on the duration, chronicity, severity, and repetitiveness of the myocardial ischemia (Figure 35-1). These different states of the myocardium can also coexist in different parts of the heart. ...
Chloe M. Park, Therese Tillin, Katherine March, Arjun K. Ghosh, Siana Jones, Andrew Wright, John Heasman, Darrel Francis, Naveed Sattar, Jamil Mayet, Nish Chaturvedi & Alun D. Hughes ...
Despite a growing body of evidence suggesting that prolonged strenuous exercise (PSE) is associated with a transient reduction in right (RV) and left ventricular (LV) performance, the exact mechanism(s) responsible for this phenomenon is not fully un
A system and method for monitoring left ventricular (LV) lateral wall motion and for optimizing cardiac pacing intervals based on left ventricular lateral wall motion is provided. The system includes
In normal subjects at rest neither heart rate nor ejection volume are influenced by age. The loss of elasticity of the great arteries, and in particular the aorta which becomes tortuous and wider, results in an increase of impedance at ejection. At systole time pressure rises in the whole cardiovascular system, so that the left ventricle is subjected to an increase of parietal tension to which it adapts itself by hypertrophy which normalizes this tension. Ejection fraction and end-systolic volume are thus preserved, and the systolic function at rest globally remains unmodified by age. The delay and slowing down of relaxation due to hypertrophy of the left ventricle, to the reflection waves and to other changes in cardiac muscle physical properties during senescence reduce the importance of the initial phase of left ventricular filling. This major modification of diastolic dynamics at rest is compensated, at the end of diastole, by a more vigorous contraction of the left atrium, which increases ...
WIDTH=92 ALIGN=LEFT VALIGN=TOP , प्रमुख कर्म ! WIDTH=111 ALIGN=LEFT VALIGN=TOP , परिवार ! WIDTH=158 ALIGN=LEFT VALIGN=TOP , लैटिन नाम ! WIDTH=345 ALIGN=LEFT VALIGN=TOP , पर्याय ! WIDTH=110 ALIGN=LEFT VALIGN=TOP , अंग्रेजी नाम ! WIDTH=73 ALIGN=LEFT VALIGN=TOP , रूप ! WIDTH=150 ALIGN=LEFT VALIGN=TOP , रासायनिक संघटन ! WIDTH=127 ALIGN=LEFT VALIGN=TOP , गुण ! WIDTH=86 ALIGN=LEFT VALIGN=TOP , रस ! WIDTH=41 ALIGN=LEFT VALIGN=TOP , विपाक ! WIDTH=42 ALIGN=LEFT VALIGN=TOP , वीर्य ! WIDTH=345 ALIGN=LEFT VALIGN=TOP , आमयिक प्रयोग ! WIDTH=86 ALIGN=LEFT VALIGN=TOP , प्रयोज्यांग ! WIDTH=57 ALIGN=LEFT VALIGN=TOP , खुराक ! WIDTH=182 ALIGN=LEFT VALIGN=TOP , विशिष्ट योग ,- , HEIGHT=25 ALIGN=CENTER VALIGN=TOP SDVAL="1" SDNUM="16393;" , 1 , ALIGN=LEFT VALIGN=TOP , अगरु , ALIGN=LEFT VALIGN=TOP ...
The freeMD virtual doctor has found 33 conditions that can cause Lower Left Sided Abdominal Tender. There are 5 common conditions that can cause Lower Left Sided Abdominal Tender. There are 3 somewhat common conditions that can cause Lower Left Sided Abdominal Tender. There are 10 uncommon conditions that can cause Lower Left Sided Abdominal Tender. There are 15 rare conditions that can cause Lower Left Sided Abdominal Tender.
Classroom course in tquk level 3 award in paediatric first aid (rqf) - (pfa) for anyone in the UK. Search for a course near you and get training by an approved ProTrainings instructor.
TY - JOUR. T1 - A new approach for evaluation of left ventricular diastolic function. T2 - Spatial and temporal analysis of left ventricular filling flow propagation by color M-mode Doppler echocardiography. AU - Takatsuji, Hiroya. AU - Mikami, Taisei. AU - Urasawa, Kazushi. AU - Teranishi, Jun Ichi. AU - Onozuka, Hisao. AU - Takagi, Chika. AU - Makita, Yasuhiro. AU - Matsuo, Hisashi. AU - Kusuoka, Hideo. AU - Kitabatake, Akira. PY - 1996/2. Y1 - 1996/2. N2 - Objectives. To evaluate left ventricular diastolic function and differentiate the pseudonormalized transmitral flow pattern from the normal pattern, the propagation of left ventricular early filling flow was assessed quantitatively using color M-mode Doppler echocardiography. Background. Because the propagation of left ventricular early filling flow is disturbed in the left ventricle with impaired relaxation, quantification of such alterations should provide useful indexes for the evaluation of left ventricular diastolic function Methods. ...
This investigation was designed to determine the role of echocardiography in the assessment of left ventricular function in patients with significant coronary arterial disease. Satisfactory echocardiograms were obtained in 43 patients with coronary arterial disease. The ventriculographic ejection fraction was determined by the area length method. The echocardiographic left ventricular end-diastolic dimension was increased to more than 5-4 cm in 17 patients. Fifteen of these patients had an ejection fraction of 0-45 or less. Three patients had a normal left ventricular end-diastolic dimension but an ejection fraction of less than 0-45. Twenty-three patients had an ejection fraction of more than 0-45 and a normal left ventricular end-diastolic dimension. The left ventricular end-diastolic dimension index was increased (greater than 3 cm/m2) in 15 patients, all of whom had ejection fraction of less than 0-45. Three patients had a normal left ventricular end-diastolic dimension index and an ejection ...
The effect of hypothyroidism on left ventricular function at rest and during exercise was studied in nine patients without demonstrable cardiovascular disease who had had total thyroidectomy and ablative radioiodine treatment for thyroid cancer. Radionuclide ventriculography and simultaneous right heart catheterisation were performed while the patients were hypothyroid two weeks after stopping triiodothyronine treatment (to permit routine screening for metastases) and while they were euthyroid on thyroxine replacement treatment. When the patients were hypothyroid, cardiac output, stroke volume, and end diastolic volume at rest were all lower and peripheral resistance was higher than when they were euthyroid. Pulmonary capillary wedge pressure, right atrial pressure, heart rate, left ventricular ejection fraction, and the systolic pressure:volume relation of the left ventricle, which was used as an estimate of the contractile state, were not significantly different when the patients were ...
TY - JOUR. T1 - Impact of Lifelong Exercise Training Dose on Ventricular-Arterial Coupling. AU - Hieda, Michinari. AU - Howden, Erin. AU - Shibata, Shigeki. AU - Fujimoto, Naoki. AU - Bhella, Paul S.. AU - Hastings, Jeffrey L. AU - Tarumi Ph.D., Takashi. AU - Sarma, Satyam. AU - Fu, Qi. AU - Zhang, Rong. AU - Levine, Benjamin D. PY - 2018/12/4. Y1 - 2018/12/4. N2 - BACKGROUND: The dynamic Starling mechanism, as assessed by beat-by-beat changes in stroke volume and left ventricular end-diastolic pressure, reflects ventricular-arterial coupling. It deteriorates with age, and is preserved in highly trained masters athletes. Currently, it remains unclear how much exercise over a lifetime is necessary to preserve efficient ventricular-arterial coupling. The purpose of this study was to assess the dose-dependent relationship between lifelong exercise training and the dynamic Starling mechanism in healthy seniors. METHODS: One hundred two seniors were recruited and stratified into 4 groups based on 25 ...
Background: We sought to evaluate the additional value of a multiparametric cardiac magnetic resonance (CMR) score in comparison with traditional TIMI (Thromolysis in Myocardial Infarction) score and transthoracic echocardiography (TTE) score in prognostic stratification of STEMI patients.. Methods: 209 STEMI patients reperfused by primary PCI underwent TTE and CMR 3 days after the index event. We measured: TIMI score, left ventricle ejection fraction (EFTTE), left ventricle end systolic volume (LVESVTTE) and number of myocardial segment with wall motion abnormalities (WMITTE) measured by TTE, left ventricle ejection fraction (EFCMR), left ventricle end systolic volume (LVESVCMR) and number of myocardial segment with wall motion abnormalities (WMICMR) measured by CMR, myocardial salvage index (MSI) and presence of microvascular obstruction (MVO). The primary clinical endpoint of study was the occurrence of major adverse cardiac events(MACE) defined as combined endpoint of hospitalization, acute ...
Anaesthetics may impair the diastolic function of the heart, but the importance of this finding for patients has not been sufficiently examined. Specially the effects on diastolic function in patients with diastolic dysfunction has to be determined. The aim of this study is to examine the effect of isoflurane (only part I), sevoflurane and desflurane (part I+II) on the diastolic left ventricular function by doppler echocardiography ...
Reliability of updated left ventricular diastolic function recommendations in predicting elevated left ventricular filling pressure and prognosis
TY - JOUR. T1 - Pioglitazone improves left ventricular diastolic function in subjects with diabetes. AU - Clarke, Geoffrey D. AU - Solis-Herrera, Carolina. AU - Molina-Wilkins, Marjorie. AU - Martinez, Sandra. AU - Merovci, Aurora. AU - Cersosimo, Eugenio. AU - Chilton, Robert J. AU - Iozzo, Patricia. AU - Gastaldelli, Amalia. AU - Abdul-ghani, Muhammad A. AU - Defronzo, Ralph A. PY - 2017/11/1. Y1 - 2017/11/1. N2 - OBJECTIVE To examine the effect of pioglitazone on myocardial insulin sensitivity and left ventricular (LV) function in patients with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS Twelve subjectswith T2Dand 12with normal glucose tolerance received a euglycemic insulin clamp. Myocardial glucose uptake (MGU) and myocardial perfusion were measured with [18F]fluoro-2-deoxy-D-glucose and [15O]H2O positron emission tomography before and after 24 weeks of pioglitazone treatment.Myocardial function and transmitral early diastolic relation/atrial contraction (E/A) flow ratio were ...
Electrocardiographic strain pattern and left ventricular diastolic function in hypertensive patients with left ventricular hypertrophy: The LIFE study Academic Article ...
Preoperative Systolic Strain Rate Predicts Postoperative Left Ventricular Systolic Function in Patients With Chronic Mitral Regurgitation: 18 Months Follow up ...
Citation: Sanchez-Martinez S, Duchateau N, Erdei T, Kunszt G, Aakhus S, Degiovanni A, Marino P, Carluccio E, Piella G, Fraser AG, Bijnens BH. Machine learning analysis of left ventricular function to characterize heart failure with preserved ejection fraction. Circ Cardiovasc Imaging. 2018 Apr 16;11(4):e007138. DOI: 10.1161/CIRCIMAGING. ...
Left ventricular function changes after cardiomyoplasty in patients with dilated cardiomyopathy.: Dynamic cardiomyoplasty has been reported in the treatment of
All information about the latest scientific publications of the Clínica Universidad de Navarra. Quantification of left ventricular function and mass in cardiac Dual-Source CT (DSCT) exams: comparison of manual and semiautomatic segmentation algorithms
I have continuous pacing following AV node ablation two years ago and have recently developed symptoms suggesting perhaps reduced left ventricular function. I have read some literature which gives com...
Multiparametric echocardiographic imaging of the failing heart is now increasingly used and useful in decision making in heart failure. The reasons for this, relies on the need of different strategies of handling these patients, as differentiation of systolic or diastolic dysfunction, as well as on the gamma of approaches available, such as percutaneous and surgical revascularization, devices implantations, and valvular regurgitations and stenosis corrections. Congestive heart failure in patients with normal left ventricular diameters or preserved left ventricular ejection fraction had been pointed out recently as present in a proportion so high as 40 to 50 percent of cases of heart failure, mainly due to the epidemics in well developed countries, as is the problem of not well controlled metabolic states (such as obesity and diabetes), but also due to the real word in developing countries, as is the case of hypertension epidemics and its lack of adequate control. As a matter of public utility, ...
Conventional right ventricular apical pacing may result in asynchronous ventricular contraction with delayed left ventricular activation, interventricular motion abnormalities, and worsening of left ventricular ejection fraction. His pacing is preserving a synchronous contraction and may prevent a decrease in left ventricular ejection fraction.. The aims of our crossover, double-blinded, randomized study is to evaluate the feasibility and long-term safety of permanent His pacing and to compare the effects on left ventricular ejection fraction of permanent His pacing with those of conventional right septal stimulation after 12 months treatment in patients with 2nd or 3rd degree AV-block. ...
Thank you for your interest in spreading the word on Hypertension.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. ...
Background:. Coarctation of the aorta (CoA) is a congenital heart disease which represents a narrowing of the proximal descending aorta, hence increasing pressure afterload to the left ventricle (LV). Conventional treatment of native CoA is surgical repair, however potential recurrence or other related complications e.g. aortic rupture, heart failure and cerebrovascular events are common. Thus, lifelong follow-up of these patients is required. Echocardiography is the most patients friendly method to evaluate CoA and in particular its effect on LV function. Moreover, the novel speckle tracking echocardiography (STE) is an important method to assess subclinical LV dysfunction, a technique that promises better evaluation of LV function in these patients.. The aims of this thesis were to review the literature on LV function in children with CoA using myocardial deformation imaging technologies, hence, to better understand the current knowledge and vagueness of the scientific evidence. We also aimed ...
The main finding of the present study is that IR is associated with LVDD independent of overt diabetes. These finding persist after adjustment for CAD, hypertension, age, sex, history of previous myocardial infarction, history of previous coronary angioplasty, EF and glycaemic control. To our knowledge, this is the first study that demonstrated an association in a population of patients without a history of diabetes focusing on the published current guidelines for the diagnosis of LVDD.. Furthermore, our date confirm the observations that T2DM is associated with LVDD [9], which is considered a precursor of diabetic cardiomyopathy. In addition, we were able to extend the findings in previous studies showing the association between LVDD and IGT.. These findings are in line with a limited number of studies that assessed the relationship between prediabetes and LVDD mainly in population based studies [11]. Nevertheless, there are some concerns about methodological issues involving the identification ...
The left ventricle is one of four chambers of the heart. It is located in the bottom left portion of the heart below the left atrium, separated by the mitral valve. As the heart contracts, blood eventually flows back into the left atrium, and then through the mitral valve, whereupon
Assessment of left ventricular (LV) systolic function is important for diagnosis, management, follow-up, and prognostic evaluation of patients in a variety of clinical settings. Accurate and reliable determination of LV systolic function is important
AIMS: We examined the effect of norepinephrine (NE) infusion on left ventricular function and apoptotic genes during progression of polymicrobial sepsis. METHODS: Male Sprague-Dawley rats (350-400 g) were made septic by intraperitoneal (i.p.) administration of 200mg/kg cecal inoculum. Sham animals received 5% dextrose water, i.p. Echocardiography was performed at baseline, 3 days and 7 days post-sepsis/sham. NE (0.6 μgkg(-1)h(-1)) was infused for 2h, before the end of day 3 of echocardiography. At the end of day 7, rats were euthanized and heart tissues harvested for isolation of total RNA. PCR was performed using RT(2) profiler™ PCR array PARN-012 (Rat apoptosis array; SuperArray, MD) using RT(2) Real-Time™ SYBR Green PCR master mix PA-012. KEY FINDINGS: NE-infusion resulted in a significant decrease in the left ventricular ejection fraction (EF) (62.56±2.07 from the baseline 71.11±3.23, p SIGNIFICANCE: The data suggest that upregulation of a series of pro-apoptotic molecules could be
The third ventricle is one of the four ventricles in the brain that communicate with one another. As with the other ventricles of the brain, it is filled with cerebrospinal fluid, which helps to protect the brain from injury and transport nutrients and waste.
The ejection fraction is a measurement of the hearts efficiency and can be used to estimate the function of the left ventricle, which pumps blood to the rest of the body.. The left ventricle pumps only a fraction of the blood it contains. The ejection fraction is the amount of blood pumped divided by the amount of blood the ventricle contains. A normal ejection fraction is more than 55% of the blood volume. If the heart becomes enlarged, even if the amount of blood being pumped by the left ventricle remains the same, the relative fraction of blood being ejected decreases. For example:. ...
Physiological effects of percutaneous interventions / Coronary stenting in challenging cases 1244 , Loss of functional recovery In regional wall motion Is predictive for restenosis of the supplying angloplasty vessel - follow-up echocardtographlc study after high-risk angloplasty Adrian C. Borges, Franz Xaver Kleber, Dorothee SchOrger, Qert Baumann, Rosa Sicari, Alessandro Plngitore, Eugenio Rcano 1 . Medical Department I, Humbotdt-Unlverslty BerSn (Charite), Germany;1 Physiologic CSnic, CNR Pisa, Italy, on behalf of the VIDA (Viability Identification with Dobutantine-CHpyiidamote Adrrfnistmtion}Study Group The prediction of functional regional recovery Is possible wtth pharmacological stress echocarcbography and has In patients with severe left ventricular dysfunction and coronary artery disease a great prognostic Impact The aim of the study was to evaluate If the loss of recovery of regional left ventricular function after successful revascuiarization can predict a restenosis of the target ...
Overview Normal LV contraction Global & regional indices of LV systolic Function Angiographic assessments Echocardiography MRI Computed Tomography Nuclear Imaging Take home message
Diabetic patients were well-matched with controls (Figure 1). Myocardial energetics were disturbed (PCr/ATP ratio: 1.44 ± 0.35 vs. 1.98 ± 0.18, p , 0.001) and myocardial triglyceride content increased (1.06 ± 0.61 vs. 0.48 ± 0.24%, p = 0.01), despite the relatively short disease duration. Peak systolic circumferential strain was reduced, indicating subtle regional LV dysfunction. However, left ventricular volumes, mass and ejection fraction, as well as echocardiographic indices of diastolic function were similar in both groups. Furthermore, despite the metabolic abnormalities observed in diabetics, there was no difference in native T1 values (as a measure of myocardial fibrosis) between diabetic patients and controls (1181 ± 28 ms vs. 1195 ± 33 ms, p = 0.30 ...
Objective: To evaluate the value of two-dimensional strain rate imaging (STE) in detecting the alteration of regionally left ventricular long-axis sys..
Alterations of LVEDP during IR; left ventricular end diastolic pressure (LVEDP); control-ischemia reperfusion (C-IR), C-ischemic postconditioning (C-IPost), hyp
When we have to decide which of two drugs, interventions, or management strategies is the better, the most secure evidence is generally obtained from a randomised controlled trial. The primary objective of randomisation is to ensure that all other factors that might influence the outcome will be equally represented in the two groups, leaving the treatment under test as the only dissimilarity. Any difference in outcome can then be attributed to the treatment effect. But how realistic is this assumption in practice?. When published a randomised trial typically includes a table listing all the prior factors known actually or possibly to influence outcome. The average age and its distribution in each group and the proportion of men and women usually head the list, followed by other likely determinants of outcome. In the case of heart disease these will probably include details of left ventricular function; the proportions in each group with diabetes, hypertension, hyperlipidaemia, or a smoking ...
The ABC-VT score accurately predicts adverse events in patients with frequent PVCs and preserved left ventricular function -- a group whose management remains unclear.