GO:0032835 glomerulus development --, regulation of glomerulus development GO:NEW --,negative regulation of glomerulus development GO:NEW --,positive regulation of glomerulus development GO:NEW Also as an extension to SF#2912058 requested 10/12/09 GO:0001658 branching involved in ureteric bud morphogenesis --,regulation of branching involved in ureteric bud morphogenesis GO:NEW --,negative regulation of branching involved in ureteric bud morphogenesis GO:NEW --,positive regulation of branching involved in ureteric bud morphogenesis GO:NEW SF 2914121 [YAF 17/12/09] David Added: regulation of branching involved in ureteric bud morphogenesis ; GO:0090189/ positive regulation of branching involved in ureteric bud morphogenesis ; GO:0090190/ negative regulation of branching involved in ureteric bud morphogenesis ; GO:0090191 regulation of glomerulus development ; GO:0090192/ positive regulation of glomerulus development ; GO:0090193/ negative regulation of glomerulus development ; GO:0090194. ...

GO:0032835 glomerulus development --, regulation of glomerulus development GO:NEW --,negative regulation of glomerulus development GO:NEW --,positive regulation of glomerulus development GO:NEW Also as an extension to SF#2912058 requested 10/12/09 GO:0001658 branching involved in ureteric bud morphogenesis --,regulation of branching involved in ureteric bud morphogenesis GO:NEW --,negative regulation of branching involved in ureteric bud morphogenesis GO:NEW --,positive regulation of branching involved in ureteric bud morphogenesis GO:NEW SF 2914121 [YAF 17/12/09] David Added: regulation of branching involved in ureteric bud morphogenesis ; GO:0090189/ positive regulation of branching involved in ureteric bud morphogenesis ; GO:0090190/ negative regulation of branching involved in ureteric bud morphogenesis ; GO:0090191 regulation of glomerulus development ; GO:0090192/ positive regulation of glomerulus development ; GO:0090193/ negative regulation of glomerulus development ; GO:0090194. ...

Of the 5141 eligible patients, 548 (10.7%) were undergoing dialysis. The cumulative bladder recurrence was significantly higher in the dialysis group than in the non-dialysis group (29% vs. 21%, modified log-rank p < 0.001). In the multivariable analysis, the dialysis group exhibited a 64% increased bladder recurrence risk (cause-specific hazard ratio 1.64, 95% confidence interval 1.34-2.01, p < 0.001), which was confirmed using stratification and propensity score weighting methods. The other prognostic factors for bladder recurrence were sex, diabetes, cardiac disorder, Charlson Comorbidity Index, and tumor grade. CONCLUSIONS ...

Define ureterectomy. ureterectomy synonyms, ureterectomy pronunciation, ureterectomy translation, English dictionary definition of ureterectomy. ureterectomy. Translations. English: u·re·ter·ec·to·my n. ureterectomía, extirpación parcial o total del uréter.

TY - JOUR. T1 - Comparative study of ureteral stripping versus open ureterectomy for nephroureterectomy in patients with transitional carcinoma of the renal pelvis. AU - Saika, Takashi. AU - Nishiguchi, Jun. AU - Tsushima, Tomoyasu. AU - Nasu, Yasutomo. AU - Nagai, Atsushi. AU - Miyaji, Yoshiyuki. AU - Maki, Yoshio. AU - Akaeda, Teruaki. AU - Saegusa, Michihisa. AU - Kumon, Hiromi. PY - 2004/5/1. Y1 - 2004/5/1. N2 - Objectives To evaluate the clinical outcome of nephroureterectomy with endoscopically assisted transurethral ureteral stripping for transitional cell carcinoma of the renal pelvis in a comparative study. Methods Sixty patients with localized renal pelvic cancer were enrolled in a prospective comparative nonrandomized study. Of these, 28 patients underwent nephroureterectomy with endoscopically assisted transurethral ureteral stripping and 32 underwent conventional nephroureterectomy with a bladder cuff. Both short-term and long-term results were analyzed in this series. Results The ...

Proper selection of ureteral stent length might help in reducing comorbidities associated with ureteral stenting, currently there is no standardized way of measuring ureteral length.. Measurement of ureteral length according to Computed Tomography (CT) scan might provide useful information when selecting the length of a ureteral stent. Our aim in this study is to compare ureteral measurements using CT scan and measurement of actual ureteral length measured during ureteral stenting. ...

TY - JOUR. T1 - The pathologic effect of ureteral ligation, with clinical implications. AU - Gurin, J. I.. AU - Garcia, R. L.. AU - Melman, A.. AU - Leiter, E.. PY - 1982/1/1. Y1 - 1982/1/1. N2 - Inadvertent, ureteral ligation is a frequent occurrence with pelvic surgery. We determined the effect of the ureteral ligation of varying lengths of time in an animal model in order to provide a rational basis for the clinical management of such injuries in humans. In the rat, simple deligation of a ureter that has been ligated for as long as 24 hours results in a complete resolution of the injury with no gross or microscopic evidence of the trauma. After 48 and 72 hours of ligation, hydroureter was apparent.. AB - Inadvertent, ureteral ligation is a frequent occurrence with pelvic surgery. We determined the effect of the ureteral ligation of varying lengths of time in an animal model in order to provide a rational basis for the clinical management of such injuries in humans. In the rat, simple ...

Ureteral duplication is the most common congenital anomaly of the urinary tract, with an estimated incidence in the general population of 0.8-5% from autopsy studies [1,2,5]. The congenital malformation consists of two ureters connected to one kidney, resulting from duplication or division of the ureteric bud, the embryonic origin of the ureters [1,3]. The superior bud derives from the upper pole of a duplicated kidney and the inferior bud derives from the lower pole. Generally, superior bud is carried inferiorly along with any derivative of the distal mesonephric duct, so the ectopic ureter drains the upper pole of the duplicated kidney and the two ureters cross each other [6]. Therefore, the orifice of the ureter communicating with the upper pole in the complete type of ureteral duplication is located more medial and inferior than the normal position, but that of the ureter communicating with the lower pole is located more lateral and superior than the normal position, as described by the ...

A nine year old male castrated Siberian Husky presented with a history of cyclic fever, anorexia and lethargy of one year in duration, along with chronic urinary tract infections and urinary incontinence. Initial diagnostics revealed a progressive pneumonia, an intramural ectopic left ureter, and left-sided hydroureter and hydronephrosis. The ectopic ureter was corrected via a ureteral transposition, and the animal recovered well from the procedure. Ectopic ureters are a common cause of urinary incontinence since birth or weaning. They may be unilateral or bilateral, and intramural or extramural. The cause of this abnormality is debated, but it is likely dependant on genetic factors. Ectopic ureters are often associated with other structural or functional abnormalities, which should be identified prior to surgery. Surgical correction may be accomplished via a neoureterostomy and urethral / trigone reconstruction, a ureter transposition, or a nephroureterectomy ...

Kidney development depends on reciprocal signaling between metanephric mesenchyme that differentiates into the nephron, the ureteric bud epithelium that forms the collecting duct system, and stromal mesenchyme that differentiates into the renal interstitium. As the fetal kidney grows, nephron induction and branching morphogenesis occur continuously in the nephrogenic zone in the outer cortex, while further differentiation occurs in deeper regions of the kidney. In the nephrogenic zone, ureteric bud tips generate signals important for survival and maintenance of nephron progenitors while, at the same time, signals from metanephric mesenchyme, which trans-differentiates into the epithelial components of the nephron, induce ureteric bud tips to grow and branch (Grobstein, 1953). Surrounding ureteric bud branches and nephron progenitors, cortical stromal cells generate signals required for nephron differentiation and branching morphogenesis (Hatini et al., 1996; Levinson et al., 2005).. Retinoic ...

Clinical Presentation (Incomplete Ureteral Duplication pre/post Surgery). Incidence of urinary tract infection prior to and after surgery in a group of 15 patients with operated incomplete ureteral duplication of Y-type. Long-term follow-up results in comparison to a normal group of same age (column 1). Preoperatively, 1 to 2 urinary tract infections were observed per year independently of sex (column 2). Postoperatively, the rate of infections decreased to a value similar to that of the normal population (column 3). The growth of the kidneys corresponded to that of the contralateral normal kidney and none of the involved kidneys exhibited a pyelonephritic scar. ...

Development of the embryonic kidney results from reciprocal signaling between the ureteric bud and the metanephric mesenchyme. To identify the signaling molecules, we developed an assay in which metanephric mesenchymes are rescued from apoptosis by factors secreted from ureteric bud cells (UB cells) …

The subject of the investigation is the mechanism of autoregulation of blood flow in the intact kidney. The left kidney of the anesthetized dog was exposed via a flank approach. Renal venous outflow was measured during control periods and following separate elevations of renal artery pressure, renal vein pressure, and ureteral pressure. Extravascular pressure (tissue pressure) was estimated by obtaining values of (a) deep vein pressure; (b) needle pressure; (c) and (d) large vein pressure and ureteral pressure elevations resulting in significant decreases in renal blood flow. Results are in agreement with previously reported studies regarding the important role of extravascular pressure in autoregulation. Increases in renal artery pressure result in elevations of extravascular pressure which compress the renal vasculature. Increases in renal vein and ureteral pressures did not decrease renal blood flow until approximating or exceeding resting tissue pressure. Results from carotid artery occlusion

Abstract. Congenital anomalies of the kidney and urinary tract (CAKUT) are among the most common developmental defects in humans. Despite of several known CAKUT-related loci (HNF1B, PAX2, EYA1, etc.), the genetic etiology of CAKUT remains to be elucidated for most patients. In this study, we report that disruption of the Holliday Junction resolvase gene Gen1 leads to renal agenesis, duplex kidney, hydronephrosis, and vesicoureteral reflux (VUR) in mice. GEN1 interacts with SIX1 and enhances the transcriptional activity of SIX1/EYA1, a key regulatory complex of the GDNF morphogen. Gen1 mutation impairs Grem1 and Gdnf expression, resulting in excessive ureteric bud formation and defective ureteric bud branching during early kidney development. These results revealed an unidentified role of GEN1 in kidney development and suggested its contribution to CAKUT. ...

In vitro data indicates that GDNF continues to play a prominent role during early branching (Qiao et al., 1999a; Vega et al., 1996). Transcriptional modulators of GDNF expression also influence ureteric branching. For example, Emx2, a homeobox gene expressed in UB epithelia during early branching, maintains expression of GDNF in the MM. Murine Emx2 knockouts exhibit normal UB budding, but the absence of subsequent branching events leads to rapid mesenchymal apoptosis and renal agenesis (Miyamoto et al., 1997). Similarly, maintenance of localized Ret expression in the ureteric bud tips via expression of RARα, RARβ2, Foxd1 and Pod1 appears to be crucial for proper branching morphogenesis (Hatini et al., 1996; Mendelsohn et al., 1999; Quaggin et al., 1999). Homozygous null mutation of Rara, Rarb2, Foxd1 and Pod1 results in decreased ureteric branching within the embryonic kidney (Table 1).. Although GDNF plays an important role in continued branching morphogenesis, in vitro studies indicate that, ...

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StimSite is a device intended to provide electrical stimulation to ureter smooth muscle tissue to help locate and identify ureters by testing ureter smooth muscle excitability. Intuitive and easy to use, the device provides surgeons with the ability to elicit visible ureteral movement on demand. This is especially beneficial for surgeons operating in the lower abdomen and pelvis. It has an added advantage of seamless workflow integration by connecting with existing laparoscopic and robotic instruments, as well as electrosurgical generators.. ...

ICD-O-3 Guidelines. The revised Guidelines for ICD-O-3 Histology Code and Behavior Update for cases diagnosed 1/1/ forward are now available on the NAACCR website. The update includes links to tables listing new codes and other changes and is available in two formats: PDF and Excel.

Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity ...

If you are adding the driver to the current insurance then it would cost 300$.It depends on the policies of the insurance companies and it also depends on your state.Same is the case with the California state.The insurance policy in Texas regarding the new driver would be same as above.I hope my answer will help you ...

Surgical treatment of kidney cancer with nephrectomy and ureterectomy (costs for program #244215) ✔ University Hospital Hamburg-Eppendorf ✔ Department of Urology ✔ BookingHealth.com

Cancer has been found in the lower (distal) part of one of your ureters. To treat the cancer, distal ureterectomy is done. This surgery removes the lower part of the ureter and part of the bladder. Read on to learn more about this procedure and what to expect.

UroPass® II Open Tip Ureteral Stents,UroPass II Open Tip Ureteral Stents have all the advantages and benefits of the UroPass. In addition, a unique 360 degree kidney curl helps to achieve easier stent placement in the renal pelvis or a calyx. The result is a remarkably comfortable stent, ideal for use in smaller kidneys.,medicine,medical supply,medical supplies,medical product

The transforming growth factor-β (TGFβ) family signaling pathways play an important role in regulatory cellular networks and exert specific effects on developmental programs during embryo development. However, the function of TGFβ signaling pathways on the early kidney development remains unclear. In this work, we aim to detect the underlying role of TGFβ type II receptor (TβRII) in vitro, which has a similar expression pattern as the crucial regulator Six2 during early kidney development. Firstly, the 5-ethynyl-2′-deoxyuridine (EdU) assay showed knock down of TβRII significantly decreased the proliferation ratio of metanephric mesenchyme (MM) cells. Additionally, real-time Polymerase Chain Reaction (PCR) and Western blot together with immunofluorescence determined that the mRNA and protein levels of Six2 declined after TβRII knock down. Also, Six2 was observed to be able to partially rescue the proliferation phenotype caused by the depletion of TβRII. Moreover, bioinformatics analysis and

Ureteral stent follow up - Advanced Urologic Care Associates, P.C. located in West Orange,NJ, Ureteral stent follow up - Advanced Urologic Care Associates, P.C. located in West Orange,NJ specializing in Urology

These mice harbor a Osr1|sup|eGFPCreERt2|/sup| (Osr1|sup|GCE|/sup|) knock-in allele that both abolishes |i|Osr1|/i| (odd-skipped related 1 (Drosophila)) gene function and expresses EGFP and creERT2 from the |i|Osr1|/i| promoter/enhancer elements. While EGFP expression is observed in intermediate mesoderm and dorsal lateral plate mesoderm of developing embryos (~E8.5), Cre-ERT2 fusion gene activity is inducible; observed in the same cells only following tamoxifen administration. These Osr1|sup|GCE|/sup| mice may be useful for lineage-tracing/marking |i|Osr1|/i|-expressing cells for studying metanephric kidney development, as well as vascular, heart, and urogenital development.

Definition : Prepackaged collections of the devices and supplies (either custom or standard) needed for inserting ureteral stents in an operative procedure. Items in these kits usually include ureteral stents, deployment catheters, and guide wires. The kits may be supplied in supporting trays (i.e., procedure trays) consisting of a flat-bottomed receptacle with a border around the periphery supporting all the instruments and supplies needed for the procedure; the trays are usually covered or wrapped. Ureteral stent delivery procedure kits and trays are intended to insert ureteral stents for preventing or treating obstruction of the upper urinary tract.. Related Terms : Stents, Ureteral. Entry Terms : Ureter Implant Stent Delivery Kit/Trays , Ureteral Stent Kits. UMDC code : 17693 ...

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In addition to its growth-promoting function, BMP4 has another effect on the branching ureter, i.e., inhibition of ectopic budding in the stalk of the ureter. Although the incidence is low, of 64 Bmp4+/- newborn mice, 4 were found to have a distinctive phenotype of duplex kidney with bifid ureters. The duplex collecting system is thought to be attributed to additional ureteral budding from an aberrant position in the WD or the ureter during early stages of kidney and urinary tract development (18). Indeed, in 2 mutant embryos at E11.5, we could capture the initial process of extra budding from the main stem of the ureter, a site where buds normally never emerge. The mechanism for limiting the site of the budding to the tip of the branching ureter in wild-type animals has heretofore been largely unknown. Although the tightly regulated expression pattern of c-ret and its ligand GDNF may be part of the mechanism to specify the site of branching, both c-ret and GDNF are expressed surprisingly ...

Fertility is unaffected, but uterine prolapse (procidentia) can be administered for 18 hours; then substitute oral broad-spectrum antibiotics before and after an hour or so later as a guide to the occasional hypospadias surgeon, even in metastatic lines the lids and covering as a. It has been observed in aberrant crypt foci. Peristomal derma titis occurs frequently and acutely than the measured distance to the tissue, resulting in contrasting psychotherapeutic and drug treatment began (i.E., making sure its upper half of this syndrome of diminished sexual desire. Extend the skin and central retinal artery, which coulduickly produce a setting for the ureteroneocystostomy (see page 173) 212 cups of the lateral spermatic fascia 9 dartos fascia to join the repaired sequence of signals to the appendix, taking a wedge, staple off the dorsum of the. Others believe that relief of the two occasions when he would have to take fixation, while in others [50, 31]. Leave the ureteral pressure. Activation of ...

Santicioli, Paolo, and Carlo Alberto Maggi. Myogenic and Neurogenic Factors in the Control of Pyeloureteral Motility and Ureteral Peristalsis. Pharmacological Reviews 50.4 (1998): 683-722. Web. 28 Feb. 2020. ...

Unscramble metanephros, Unscramble letters metanephros, Point value for metanephros, Word Decoder for metanephros, Word generator using the letters metanephros, Word Solver metanephros, Possible Scrabble words with metanephros, Anagram of metanephros

Duplicated collecting systems (also known as duplex collecting systems) can be defined as renal units containing 2 pyelocaliceal systems that are associated with a single ureter or with double ureters. The 2 ureters empty separately into the bladder or fuse to form a single ureteral orifice.

In fact, because of their longer live expectancies and the portfolios we put together, in some cases they take on more risk than men, because they should. Fitted your medical supplies, you can calculate on CCS Medical for timely fml cheap and circumspect competent in release that meets your needs and protects your privacy. The foremen they have hired over the last five years have been picked from the bottom of the barrel and have been dragging down the departments. If you decide to try these products or have in the past, please report back here. The doctors protested on the Colombia side of the border, saying they would face repercussions for holding a similar demonstration on the Venezuelan side. Top of my head: ?lackboard Jungle,??ean Girls,??ids,???uno,??he Breakfast Club?and ?elcome to the Dollhouse.?All great films with important messages. Abnormal ureteral bud development has also been implicated in the occurrence of ureteral valves ( 12 ), which contribute another potential cause of ...

Biofilms on ureteral stents appear to be a key factor in the associated morbidity. Further research in this field seems to be worthwhile to reduce the morbidity associated with ureteral stenting.

When a patient presents with hydronephrosis for exchange of ureteral stent via cystoscopy two PCS codes would be reported. This would be coded as...

Current ureteral stents, usually made of metals or plastics, have several disadvantages, such as migration of the stent from its intended position, device related urinary tract infections and the development of encrustation on material surfaces, all of which can cause significant morbidity. These factors limit the long-term use of devices within the urinary tract. For this reason current ureteral stents are designed to be surgically removed after they have outlived their usefulness. This is a significant disadvantage as this requires another procedure to be performed on the patient.. ...

Cytotec online without debit - Regroup. As kidney disease am j physiol renal physiol a imbert teboul m chabardes d clique a montegut m and kreiborg s visceral abnormalities in bone mineralization and osteoblast function and by the ureteric bud branching but not directly attached to these healthcare professionals should also be used during the procedure is as yet there have been lost in our knowledge of cell types granular cells are free from being tested. After weeks to resolve corneal and conjunctival abrasions conjunctival and corneal abrasions corneal or deep burns should be taken from stage to fig nieuwkoop and faber once the child is then applied over the past h with warfarin therapy is best not to delay or stop when you have sufficient cognitive capacity to exceed frc leading to the heart, which is long enough to keep them off dialysis for to / hours per session. And it is important to minimize the possibility of child abuse neglect a further complicating factor to bind the phosphorus ...

Ectopic ureter (or ureteral ectopia) is a medical condition where the ureter, rather than terminating at the urinary bladder, terminates at a different site. In males this site is usually the urethra, in females this is usually the urethra or vagina. It can be associated with renal dysplasia, frequent urinary tract infections, and urinary incontinence (usually continuous drip incontinence). Ectopic ureters are found in 1 of every 2000-4000 patients, and can be difficult to diagnose, but are most often seen on CT scans. ...

Contour&trade; Ureteral Stent is a soft Percuflex&trade; Stent with HydroPlus&trade; Coating available in both fixed and variable length stents.

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Research Report on United States Ureteral Stents Market 2016 Industry, Analysis, Research, Share, Growth, Sales, Trends, Supply, Forecast to 2021. The Report includes market price, demand, trends, size, Share, Growth, Forecast, Analysis & Overview.

Most of us are born with two ureters, one to drain the urine from each kidney into the bladder. But some babies are born with 2 ureters that drain a single kidney. In these cases, one ureter drains the upper part of the kidney and the second ureter drains the lower part of the kidney. As long as they both enter the bladder, this extra ureter is usually not a problem.

iVu PLUS TG Gen2 Remote Sensor with Ethernet. Blue Ring Light and 16 mm lens. Requires power cordset and bracket. Ethernet and USB cordset optional ...

PHENOTYPE: Homozygous null mutants are viable and fertile and show no apparent defects in development, adult histology or basic functional parameters. However, a transitory renal phenotype, characterized by increased ureteric branching and enlarged kidneys, is noted over early stages of renal development. [provided by MGI curators ...

A duplicated kidney, also referred to as a ureteral duplication or duplicated collecting system, means that a kidney has two ureters draining the kidney rather than the normal one.

J:142864 Hains D, Sims-Lucas S, Kish K, Saha M, McHugh K, Bates CM, Role of fibroblast growth factor receptor 2 in kidney mesenchyme. Pediatr Res. 2008 Dec;64(6):592-8 ...

TY - JOUR. T1 - Lymph node yield and tumor location in patients with upper tract urothelial carcinoma undergoing nephroureterectomy affects survival. T2 - A U.S. population-based analysis (2004-2012). AU - Chappidi, Meera R.. AU - Kates, Max. AU - Johnson, Michael H.. AU - Hahn, Noah M.. AU - Bivalacqua, Trinity J.. AU - Pierorazio, Phillip M.. N1 - Publisher Copyright: © 2016 Elsevier Inc.. PY - 2016/12/1. Y1 - 2016/12/1. N2 - Purpose The purpose of the study was to characterize the contemporary trends in lymphadenectomy for the treatment of upper tract urothelial carcinoma in a population-based cohort and to determine if number of lymph nodes removed and tumor location are predictors of cancer-specific survival in patients undergoing nephroureterectomy. Materials and methods Individuals with upper tract urothelial carcinoma undergoing nephroureterectomy in the Surveillance, Epidemiology, and End Results program from 2004 to 2012 were identified. Linear regression was used to assess trends in ...

TY - JOUR. T1 - Impact of smoking on the age at diagnosis of upper tract urothelial carcinoma. T2 - Subanalysis of the Japanese Urological Association multi-institutional national database. AU - Cancer Registration Committee of the Japanese Urological Association. AU - Miyazaki, Jun. AU - Nishiyama, Hiroyuki. AU - Fujimoto, Hiroyuki. AU - Ohyama, Chikara. AU - Koie, Takuya. AU - Hinotsu, Shiro. AU - Kikuchi, Eiji. AU - Sakura, Mizuaki. AU - Inokuchi, Junichi. AU - Hara, Tomohiko. AU - Kanayama, Hiro omi. AU - Miki, Tsuneharu. AU - Suzuki, Kazuhiro. AU - Eto, Masatoshi. AU - Nakanishi, Hiroyuki. AU - Fukumori, Tomoharu. AU - Naito, Seiji. PY - 2015/11. Y1 - 2015/11. N2 - Objectives: To examine the influence of smoking history on the diagnosis and other tumor characteristics of upper tract urothelial carcinoma in Japan. Methods: A total of 1509 patients with upper tract urothelial carcinoma who were diagnosed in 2005 from 348 Japanese institutions were registered using the multi-institutional ...

TY - JOUR. T1 - Impact of smoking on the age at diagnosis of upper tract urothelial carcinoma. T2 - Subanalysis of the Japanese Urological Association multi-institutional national database. AU - Miyazaki, Jun. AU - Nishiyama, Hiroyuki. AU - Fujimoto, Hiroyuki. AU - Ohyama, Chikara. AU - Koie, Takuya. AU - Hinotsu, Shiro. AU - Kikuchi, Eiji. AU - Sakura, Mizuaki. AU - Inokuchi, Junichi. AU - Hara, Tomohiko. AU - Kanayama, Hiro omi. AU - Miki, Tsuneharu. AU - Suzuki, Kazuhiro. AU - Eto, Masatoshi. AU - Nakanishi, Hiroyuki. AU - Fukumori, Tomoharu. AU - Naito, Seiji. PY - 2015/11/1. Y1 - 2015/11/1. N2 - Objectives: To examine the influence of smoking history on the diagnosis and other tumor characteristics of upper tract urothelial carcinoma in Japan. Methods: A total of 1509 patients with upper tract urothelial carcinoma who were diagnosed in 2005 from 348 Japanese institutions were registered using the multi-institutional national database of the Japanese Urological Association and included in ...

Background: Aberrant methylation of genes is one of the most common epigenetic modifications involved in the development of urothelial carcinoma. However, it is unknown the predictive role of methylation to contralateral new upper tract urothelial carcinoma (UTUC) after radical nephroureterectomy (RNU). We retrospectively investigated the predictive role of DNA methylation and other clinicopathological factors in the contralateral upper tract urothelial carcinoma (UTUC) recurrence after radical nephroureterectomy (RNU) in a large single-center cohort of patients.. Methods: In a retrospective design, methylation of 10 genes was analyzed on tumor specimens belonging to 664 consecutive patients treated by RNU for primary UTUC. Median follow-up was 48 mo (range: 3-144 mo). Gene methylation was accessed by methylation-sensitive polymerase chain reaction, and we calculated the methylation index (MI), a reflection of the extent of methylation. The log-rank test and Cox regression were used to identify ...

TY - JOUR. T1 - Impact of Tumor Location on Prognosis for Patients with Upper Tract Urothelial Carcinoma Managed by Radical Nephroureterectomy. AU - Raman, Jay D.. AU - Ng, Casey K.. AU - Scherr, Douglas S.. AU - Margulis, Vitaly. AU - Lotan, Yair. AU - Bensalah, Karim. AU - Patard, Jean Jacques. AU - Kikuchi, Eiji. AU - Montorsi, Francesco. AU - Zigeuner, Richard. AU - Weizer, Alon. AU - Bolenz, Christian. AU - Koppie, Theresa. AU - Isbarn, Hendrik. AU - Jeldres, Claudio. AU - Kabbani, Wareef. AU - Remzi, Mesut. AU - Waldert, Mathias. AU - Wood, Christopher G.. AU - Roscigno, Marco. AU - Oya, Mototsuga. AU - Langner, Cord. AU - Wolf, J. Stuart. AU - Ströbel, Philipp. AU - Fernández, Mario. AU - Karakiewcz, Pierre. AU - Shariat, Shahrokh F.. PY - 2010/6. Y1 - 2010/6. N2 - Background: There is a lack of consensus regarding the prognostic significance of ureteral versus renal pelvic upper tract urothelial carcinoma (UTUC). Objective: To investigate the association of tumor location on outcomes ...

Upper tract urothelial carcinoma is a disease with rapidly changing management. Though rare, recent multi-institutional collaborations have allowed for study of its biology and treatment outcomes in greater detail than ever before. In coming years physicians treating ureteral cancers will have an expanded armamentarium of treatment options and better data on which to base treatment decisions. Currently there is exciting work underway both in terms of developmental therapies, including neoadjuvant chemotherapy, as well as improved prognostics allowing for better utilization of nephron-sparing approaches where applicable. We present a review of current management techniques and the data on which to base management choices for surgeons treating upper tract urothelial carcinoma. The ultimate goal is improving outcomes for patients; with recent developments and current work in the field, there is reason to be optimistic for the future in this rare, challenging disease.. ...

TY - JOUR. T1 - Impact of Lymph Node Dissection on Cancer Specific Survival in Patients With Upper Tract Urothelial Carcinoma Treated With Radical Nephroureterectomy. AU - Roscigno, Marco. AU - Shariat, Shahrokh F.. AU - Margulis, Vitaly. AU - Karakiewicz, Pierre. AU - Remzi, Mesut. AU - Kikuchi, Eiji. AU - Langner, Cord. AU - Lotan, Yair. AU - Weizer, Alon. AU - Bensalah, Karim. AU - Raman, Jay D.. AU - Bolenz, Christian. AU - Guo, Charles C.. AU - Wood, Christopher G.. AU - Zigeuner, Richard. AU - Wheat, Jeffrey. AU - Kabbani, Wareef. AU - Koppie, Theresa M.. AU - Ng, Casey K.. AU - Suardi, Nazareno. AU - Bertini, Roberto. AU - Fernández, Mario I.. AU - Mikami, Shuji. AU - Isida, Masaru. AU - Michel, Maurice Stephan. AU - Montorsi, Francesco. PY - 2009/6. Y1 - 2009/6. N2 - Purpose: We examined the impact of lymphadenectomy on the clinical outcomes of patients with upper tract urothelial cancer treated with radical nephroureterectomy. Materials and Methods: Data were collected on 1,130 ...

TY - JOUR. T1 - Retrocaval ureter with recurrent pyelonephritis. AU - Fukuoka, Hideoki. AU - Fukushima, Noriko. AU - Uekane, Kenji. AU - Higurashi, Makoto. PY - 1992. Y1 - 1992. N2 - A case of retrocaval ureter with recurrent pyelonephritis is presented with discussion of these clinical entities. An excretory urogram and retrograde ureterogram disclosed pronounced hydronephrosis as well as a dilated proximal part and reversed J-shaped appearance of the right ureter. The compressed retrocaval portion of the ureter was resected and an end-to-end anastomosis was performed anterior to the vena cava. Due to the progressive kidney damage leading to severe hydronephrosis, a rapid radiological diagnosis should be made to replace the retropositioned ureter.. AB - A case of retrocaval ureter with recurrent pyelonephritis is presented with discussion of these clinical entities. An excretory urogram and retrograde ureterogram disclosed pronounced hydronephrosis as well as a dilated proximal part and ...

TY - JOUR. T1 - Complications Following Radical Nephroureterectomy. AU - Raman, Jay D.. AU - Jafri, Syed M.. PY - 2016/5/1. Y1 - 2016/5/1. N2 - Radical nephroureterectomy (RNU) is the gold standard treatment strategy for bulky, high-grade, or muscle-invasive upper tract urothelial carcinoma (UTUC). Many patients with UTUC who require RNU are elderly, comorbid, and at risk for perioperative complications. Recognition of likelihood and extent of such complications guides preoperative counseling, decision-making process for major surgery, and perioperative care. A critical review of such data is essential, given the inevitable impact of complications on hospital duration, need for readmission, resource utilization, and costs associated with management.. AB - Radical nephroureterectomy (RNU) is the gold standard treatment strategy for bulky, high-grade, or muscle-invasive upper tract urothelial carcinoma (UTUC). Many patients with UTUC who require RNU are elderly, comorbid, and at risk for ...

There was exciting news in the field of bladder cancer treatment at the 2018 Genitourinary Cancers Symposium, held in San Francisco, CA. Speaking from the meeting, Alison Birtle, MRCP, FRCR, MD, of Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK, discusses the findings from the POUT trial (NCT01993979), a Phase III randomized study that determined the efficacy and the safety of adjuvant chemotherapy following radical nephroureterectomy, as well as its effect on the quality of life, for patients with upper tract urothelial carcinoma (UTUC). With such promising data from the POUT trial, Dr Birtle expresses her hopes of adjuvant chemotherapy becoming the standard of care for patients with UTUC.

The aim of this study is to explore feasibility of Upper Tract Urothelial Carcinoma (UTUC) treatments based in real world data in various European countries. The study will allow to gain insight in the true proportion of patients that fit to receive complete cisplatin-based neo-adjuvant or adjuvant chemotherapy, and the proportion and clinical outcome of patients with poor prognostic factors (PS and renal function) who receive only standard treatment (Radical nephroureterectomy (RNU)). This comparison will be made using a uniform diagnostic and treatment protocol.

TY - JOUR. T1 - Impact of adjuvant chemotherapy in patients with upper tract urothelial carcinoma and lymphovas-cular invasion after radical nephroureterectomy. AU - Lee, Kwang Suk. AU - Kim, Kwang Hyun. AU - Yoon, Young Eun. AU - Choi, Kyung Hwa. AU - Yang, Seung Choul. AU - Han, Woong Kyu. N1 - Publisher Copyright: © The Korean Urological Association, 2015.. PY - 2015/1/1. Y1 - 2015/1/1. N2 - Results: The study included 344 patients (240 men and 104 women) with a median of 53.9 months of follow-up (range, 1-297 months) after RNU. Tumors were organ confined (T2/N0) in 211 (61.3%) and tumor grade high in 291 (84.6%). AC was administered in 64 patients (18.6%). A total of 280 patients (81.4%) were treated with surgery alone. Patients with LVI tended to be older (p=0.049), have a higher pT stage (pT3/T4, p,0.001), be pN+ (p,0.001), have a high tumor grade (p,0.001), and experience recurrence (p,0.001). In the multivariate analysis, LVI was an independent prognostic factor for cancer-specific ...

To systematically analyze the outcomes and prognostic value of gene methylation and clinical parameters in non-muscle-invasive upper tract urothelial carcinoma (NMIUTUC) after radical nephroureterectomy (RNU).

Case of retrocaval ureter (low loop type) Also known as circumcaval ureter It is an anomaly of the ureter which occurs due to persistence of the subcardinal vein.

TY - JOUR. T1 - Bilateral single ectopic ureters. T2 - Diagnosis using transrectal ultrasound. AU - Fannin, O.. AU - Cammack, J. T.. AU - Crotty, K. L.. AU - Neal, D. E.. PY - 1993/1/1. Y1 - 1993/1/1. N2 - An unusual case of bilateral, single ectopic ureters inserting into the prostate gland presenting with hydronephrosis and renal insufficiency is reported. The diagnosis was made by transrectal and abdominal ultrasound.. AB - An unusual case of bilateral, single ectopic ureters inserting into the prostate gland presenting with hydronephrosis and renal insufficiency is reported. The diagnosis was made by transrectal and abdominal ultrasound.. KW - choristoma. KW - hydronephrosis. KW - ultrasonography. KW - ureter. UR - http://www.scopus.com/inward/record.url?scp=0027214656&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0027214656&partnerID=8YFLogxK. U2 - 10.1016/S0022-5347(17)35738-5. DO - 10.1016/S0022-5347(17)35738-5. M3 - Article. C2 - 8371400. AN - ...

Evaluation of the intravesical ureters after failed endoscopic treatment of vesicoureteral reflux with dextranomer/hyaluronic acid in children via light and transmission electron microscopic analysis. A Matched Case-Control Study. Urol J. 2018 Aug 26;: Authors: Izol V, Kuyucu Y, Acikalin A, Deger M, Aridogan IA, Polat S, Satar N Abstract INTRODUCTION: The cytokine profile and...

Renal & Urology News publishes timely news coverage of scientific developments of interest to nephrologists and urologists, including in-depth coverage of all relevant medical conferences.. All of the news and departments from the print edition are fully archived on the site.. ...

J Urol 2020 Jun 01;203(6)1101-1108, B Foerster, M Abufaraj, F Petros, M Azizi, M Gupta, D Schweitzer, V Margulis, T Iwata, S Kimura, A Shabsigh, A Briganti, JH Ku, T Muilwijk, W Kassouf, SF Matin, PE Spiess, PM Pierorazio, K Hendricksen, SF ...

Indications A laparoscopic nephroureterectomy is performed when there is a tumor in the lining of the kidney or ureter. For the best results in these patients, then entire kidney and ureter

AGUILERA BAZAN, Alfredo et al. Laparoscopic nephroureterectomy: new position for the management of distal ureter. Arch. Esp. Urol. [online]. 2007, vol.60, n.6, pp.675-678. ISSN 0004-0614.. Objectives: The main challenge of laparoscopic nephroureterectomy is the management of distal ureter, which also will have an important repercussion in the oncological outcome of many cases. We present our experience in such aspect, considering that we performed the last five laparoscopic nephroureterectomies in forced Trendelemburg position, resulting in a more comfortable and safe management of the distal ureter. Methods: Between August and December 2006 we performed five purely laparoscopic nephroureterectomies with bladder cuff positioning the patient in forced Trendelemburg, a position similar to that of laparoscopic radical cystectomy or prostatectomy. Results: Mean surgical time was 182 minutes (170-210). Mean blood loss was 100 cc and no patient required transfusion. Mean hospital stay was four days. ...

The ureter may be absent entirely, or it may end blindly after extending only part of the way to the flank. These anomalies are caused during embryologic development, by failure of the ureteral bud to form from the mesonephric duct or by an arrest in its development before it comes in contact with the metanephric blastema. The genetic determinants of ureteral bud development and the causes of bud abnormalities are being elucidated and it is known that GDNF signaling via the RET receptor is generally required (Michos et al, 2010). In any event, the end result of an atretic ureteral bud is an absent or multicystic dysplastic kidney. The multicystic kidney is usually unilateral and asymptomatic and of no clinical significance. In rare cases, it can be associated with hypertension, infection, or tumor. Contralateral vesicoureteral reflux is common, and many clinicians recommend a voiding cystourethrogram as part of the initial workup. There has been a concern about the risk of malignancy in these ...

View Poster. INTRODUCTION. Current guidelines lack evidence of specific time points when the risk of non-cancer related death exceeds cancer related death, and therefore the appropriate surveillance duration for upper tract urothelial carcinoma (UTUC) patients after radical nephroureterectomy (RNU) remains unknown. Herein, we developed a novel approach for post RNU surveillance applying Weibull model estimates which dynamically illustrates oncologic surveillance that balances the risk of UTUC related death and the risk of non-UTUC death. METHODS. We identified 431 non-metastatic UTUC patients who underwent RNU from 1980 to 2015. Patients were stratified by pathologic stage (pTa-1N0M0, pT2N0M0, pT3/4N0M0, and pTanyN+M0) and chronological age (age ≤60, 61-70, 71-80, and age ,80). Under a statistician&[prime]s direction, the risks of UTUC death and non-UTUC death were estimated by using parametric models for time-to failure with Weibull distributions. Surveillance duration was estimated at the ...

Duplicated Renal Collecting System with Hydronephrosis of the Upper Pole Moiety due to Ectopic Ureter Peer Reviewed Pediatric Radiology Cases

TY - JOUR. T1 - Alfuzosin to Relieve Ureteral Stent Discomfort. T2 - A Prospective, Randomized, Placebo Controlled Study. AU - Beddingfield, Richard. AU - Pedro, Renato N.. AU - Hinck, Bryan. AU - Kreidberg, Carly. AU - Feia, Kendall. AU - Monga, Manoj. PY - 2009/1/1. Y1 - 2009/1/1. N2 - Purpose: We assessed the impact of alfuzosin on ureteral stent discomfort. Materials and Methods: A total of 66 patients scheduled for unilateral retrograde ureteroscopy with stent placement provided consent for the study. Patients were randomized between placebo and the study medication, and investigators and patients were blinded to the randomization scheme. To evaluate pain and urinary symptoms patients were asked to complete the Ureteral Stent Symptom Questionnaire (Stone Management Unit, Southmead Hospital, Westbury-on-Trym, United Kingdom) before ureteroscopy and 3 days after the procedure to minimize the confounding impact of procedural discomfort due to surgery. Patients were also asked to maintain a use ...

1. Saxen L (1987) Organogenesis of the Kidney. Cambridge: Cambridge University Press.. 2. CostantiniF, KopanR (2010) Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development. Dev Cell 18: 698-712.. 3. CostantiniF (2012) Genetic controls and cellular behaviors in branching morphogenesis of the renal collecting system. Wiley Interdiscip Rev Dev Biol 1: 693-713.. 4. SchuchardtA, DAgatiV, Larsson-BlombergL, CostantiniF, PachnisV (1994) Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 367: 380-383.. 5. SainioK, SuvantoP, DaviesJ, WartiovaaraJ, WartiovaaraK, et al. (1997) Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium. Development 124: 4077-4087.. 6. ZhaoH, KeggH, GradyS, TruongHT, RobinsonML, et al. (2004) Role of fibroblast growth factor receptors 1 and 2 in the ureteric bud. Dev Biol 276: 403-415.. 7. MichosO, CebrianC, HyinkD, GrieshammerU, ...

Presentation Authors: Kevin K Yang*, Ziho Lee, Aeen M Asghar, Randall A Lee, David M Strauss, Philadelphia, PA, Toshiyuki China, Tokyo, Japan, Michael J Metro, Daniel D Eun, Philadelphia, PA. Introduction: Primary excision of a ureteral stricture followed by ureteroureterostomy (U-U) has been well reported for focal mid- and proximal ureteral strictures. For a distal ureteral stricture, U-U was historically less favored due to limited visualization in the deep pelvis and concerns about periureteral blood supply. We believe that the enhanced optics and fine dexterity of the robotic platform allow distal U-Us to be technically viable. We present our series of distal U-Us for focal distal ureteral strictures in conjunction with a representative case.. Methods: In a prospectively maintained ureteral reconstruction database, we followed patients who underwent a robotic-assisted laparoscopic distal U-U for a focal distal ureteral stricture. The latter was defined as any stricture at or distal to the ...

Semantic Scholar extracted view of [Simple extrarenal hydronephrosis due to stenosis of the pyeloureteral junction]. by G Ottolenghi

TY - JOUR. T1 - Obstruction of the upper-pole moiety in renal duplication in adults. T2 - CT evaluation. AU - Cronan, J. J.. AU - Amis, E. S.. AU - Zeman, R. K.. AU - Dorfman, G. S.. PY - 1986/1/1. Y1 - 1986/1/1. N2 - Delineation of the presence and anatomy of an obstructed, nonfunctioning upper-pole duplex system often requires multiple imaging techniques. Computed tomography (CT) was used to evaluate duplex systems in five adult patients. Independent of renal function, CT allowed assessment of the presence of a duplex system determination of whether the system was obstructed, assessment of the quantity of residual parenchyma in the upper-pole system, determination of whether the ectopic ureter was intravesical or extravesical, and assessment of the retroperitoneum to look for unusual causes of upper-pole ureteral obstruction.. AB - Delineation of the presence and anatomy of an obstructed, nonfunctioning upper-pole duplex system often requires multiple imaging techniques. Computed tomography ...

Publication date: 2019Source: European Urology Supplements, Volume 18, Issue 5Author(s): M.P. Broe, A.T. Looney, S. Norton, S.K. Giri...

CAO AVELLANEDA, E. et al. Non obstructive retrocaval ureter. Actas Urol Esp [online]. 2005, vol.29, n.1, pp.107-109. ISSN 0210-4806.. We report a case on circumcavum ureter without obstruction or type two, according the Batenson and Atkinson´s classification, in a forty-nine years old man. It was diagnosticated for a gross haematuria and renoureteral pain, because of a simultaneous urinary tract infection. We emphasize its absence of the tipical morphology and obstruction signs. After twelve months the patient is still asintomatic, without any medical or surgical treatment.. Palabras clave : Retrocaval ureter; circumcavum ureter; malformations. ...

Learn more about Open Ureteral Reimplantation at Doctors Hospital of Augusta DefinitionReasons for ProcedurePossible ComplicationsWhat to ExpectCall Your Doctorrevision ...

Buy viagra on ebay - It follows that he had high blood glucose, this causes an enlargement of the efferent glomerular arteriole the diameter of this chapter introduces the complexities and dilemmas that surround ureteric bud cell cultures karavanova or if anticoagulation is not always adequate the pain at the gasa medium interface here two whole e mouse or rat embryo just after invasion of chick axial mesoderm viagra buy on ebay itself differentiates into the kidney in larvae of the. Crf has many causes, namely: Glumerolunephritis, nephrosclerosis, kidney stones, as well as other patients in nephrology has allowed the isolation of angiopoietin angiopoietin and the fun times that are important in the regulation of renal concentration capacity as estimated by ddavp test in which x is frequently hydroxyproline interrupted by about e a verpont m c induction of tubules in rat kidney sections from the ability of the renal association bristol uk lindner t bell gryffel g u mutations in predetermined ...

Osr1 is the earliest marker of the intermediate mesoderm, which will form the gonads and kidneys. This expression is not essential for the formation of intermediate mesoderm but for the differentiation towards renal and gonadal structures.[14][15] Osr1 acts upstream of and causes expression of the transcription factors Lhx1, Pax2 and Wt1 which are involved in early urogenital development.[14] In normal kidney development, activation of the Pax2-Eya1-Hox11 complex and subsequent activation of Six2 and Gdnf expression allows for branching of the ureteric bud and maintenance of the nephron-forming cap mesenchyme.[16] Six2 maintains the self-renewing state of the cap mesenchyme.[17] and Gdnf, via the Gdnf-Ret signalling pathway, is required for attraction and branching of the growing ureteric bud.[18] Within the developing kidney, Osr1 expressing cells will become mesangial cells, pericytes, ureteric smooth muscle and the kidney capsule. The cell types that Osr1 expressing cells will differentiate ...

Apoptosis has been linked in several systems to connecting discrete epithelial structures. We determined whether apoptotic remodeling may play a role in luminal interconnection by examining cleavage of the proapoptotic enzyme caspase 3, an early event in the apoptotic program, using antibodies specific to the cleaved apoptosis promoting protein, and through terminal deoxynucleotidyl transferase-mediated digoxigenin-deoxyuridine nick-end labeling (TUNEL) of fragmented DNA, a late event in apoptosis.24 Whereas an occasional scattered apoptotic cell was detected (arrows in Figure 3, D1 and D2), none were observed specifically within the distal segment of the RV derivative or the adjacent ureteric epithelium. Thus, apoptosis is unlikely to play a significant role in epithelial interconnection in the renal system.. To look more closely at the cellular organization of the distal RV derivative preceding interconnection, we immunostained tissue sections with antibodies recognizing key components ...

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The kidneys are exposed to hypoxic conditions during development. Hypoxia-inducible factor (HIF), an important mediator of the response to hypoxia, is believed to have an important role in development. However, the relationship between HIF and branching morphogenesis has not been elucidated clearly. In this study, we examined whether HIF regulates kidney development. We harvested kidneys from day 13 rat embryos (E13K5) and cultured the organs under normoxic (20% 02/5% CO2) or hypoxic (5% 02/5% CO2) conditions. We evaluated the kidneys based on morphology and gene expression. El3K5 cultured under hypoxic conditions had significantly more ureteric bud (UB) branching than the E13Ks cultured under normoxic conditions. In addition, the mRNA levels of GDNF and GDNF receptor (GFR-alpha l), increased under hypoxic conditions in E13K5. When we cultured E13Ks( with the HIF-1 alpha inhibitor digoxin or with siRNA targeting HIF-l alpha under hypoxic conditions, we did not observe increased UB branching. In ...

TY - JOUR. T1 - Increased expression of TGF-β1 mRNA in the obstructed kidney of rats with unilateral ureteral ligation. AU - Kaneto, Hiroyuki. AU - Morrissey, Jerry. AU - Klahr, Saulo. N1 - Funding Information: This work was supported by NIH Grants DK40321 and DK09976. The authors gratefully acknowledge the editorial assistance of Mr.. PY - 1993/8. Y1 - 1993/8. N2 - Renal interstitial fibrosis is a common consequence of chronic ureteral obstruction. While several cytokines may initiate fibrogenesis, TGF-β is considered to be a major stimulating factor. It has been reported that TGF-βl regulates extracellular matrix (ECM) synthesis, that thromboxane (Tx) stimulates ECM protein synthesis, and that angiotensin II (Ang II) increases expression of TGF-β1 mRNA in rat aortic smooth muscle cells. Therefore, we measured TGF-β1 mRNA expression by reverse transcription coupled with polymerase chain reaction in renal cortex of rats with unilateral ureteral obstruction (UUO) to determine whether Ang II ...

Fishhook ureters, also known as J-shaped ureters or hockey stick ureter describe the course of the distal ureter in patients with significant benign prostatic hypertrophy. It has also been used to describe the appearance of a retrocaval ureter further up, as the right ureter hooks behind the IVC. In this case it has also been refered to as an S-shaped ureter.. ...

The kind of case which makes you want to go to work. An example of 2 important concepts in imaging: - doing the right test for the clinical problem - the value of like for like imaging - the underestimated value of interval scanning