The report firstly introduced Ultraviolet Ray Phototherapy Apparatus basic information included Ultraviolet Ray Phototherapy Apparatus definition classification application industry chain structure industry overview; international market analysis, China domestic market analysis, Macroeconomic environment and economic situation analysis and influence, Ultraviolet Ray Phototherapy Apparatus industry policy and plan, Ultraviolet Ray Phototherapy Apparatus product specification, manufacturing process, product cost structure etc.. Browse Full Report with TOC @ http://www.qyresearchreports.com/report/global-and-china-ultraviolet-ray-phototherapy-apparatus-industry-2013-market-research-report.htm. Then statistics Global and China key manufacturers Ultraviolet Ray Phototherapy Apparatus capacity production cost price profit production value gross margin etc details information, at the same time, statistics these manufacturers Ultraviolet Ray Phototherapy Apparatus products customers application capacity ...
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Ultraviolet rays are electromagnetic rays that are invisible to the naked eye. Though long-term exposure to ultraviolet rays can...
I could not find anything related to using ultraviolet rays for energy in the ? areas I looked at. Ultraviolet rays are present 24hrs a day, rain snow or shine, has anyone come up with a way to use this abundent energy ...
As an attractive dielectric material, polyimide has been widely used in the field of electronics, aerospace, and automobiles due to its useful mechanical properties and good chemical resistance. UV irradiation was considered to be the main factor related to the damage and failure of polyimide. Here the effects of UV irradiation on the surface morphology and microscale mechanical properties of polyimide films are characterized by atomic force microscopy (AFM). The surface roughness of the UV-irradiated samples developed and the mechanical properties degraded with the radiation dose increased. For comparison, uniaxial tensile test was performed to obtain the macroscale Youngs modulus of polyimide film. The UV-irradiated damaging depth was simulated with finite element method (FEM).
Detail záznamu - Hyaluronan minimizes effects of UV irradiation on human keratinocytes - Detail záznamu - Knihovna Akademie věd České republiky
Behind the shades. For personal and professional reasons, Ive been spending a lot of time in Florida lately. And its an interesting place.. The fashions you see can leave you speechless. And the "unfashions" are even worse. The plaid pants…bright gold jogging suits…and those huge wraparound sunglasses!. Where are these people shopping?!. Turns out the people donning those curious sunglasses may not be fashionistas but they are pretty smart about protecting their eyes.. Those mega-wraparound sunglasses block nearly 100 percent of ultraviolet rays. Anything less than that increases risk of photokeratitis, which is sunburn of the cornea.. Ouch! And not only is it painful, but it can also damage and kill superficial corneal cells. And that sets up the potential for serious, long-term damage.. Of course, you dont HAVE to wear those oversized sunglasses to protect your eyes. But when you understand the consequences of UV damage, you may actually want to!. Ray of hope. Photokeratitis is an ...
There are many things we consider invasive for our skin: chemical products, pollution, stress and even aging are on our list when it comes to things which will badly affect the texture and color of the skin. However, what many people tend to ignore when it comes to their skin is the harmful effect of the sun.. Sun is one of the worst enemies the human skin could have. First of all because there are very few ways in which we can stay out of its way. Everywhere we go we have to meet the dangerous sun rays, especially during the hot days of summer. Because we got so used with it, sun no longer is seen as a threat. Moreover, there are people who benevolently expose their skin to the powerful sun rays without any protection, thus damaging their skin willingly.. But why is sun a threat to human skin after all? Well, the ultraviolet rays which come from the sun are the ones which affect the skin. People with lighter color of skin feel the solar attacks more acutely than people with darker types of ...
the 3, photo sources does not have the mercury, in the light beam not to contain the ultraviolet ray. The LED illumination is the solid illumination photo source,LED lamps the green bosom, is suitable specially for the perfume shop, the slum joint, the museum, the art museum and so on specialized place, may satisfy its demonstration commodity to the illumination special request; the 4, state system illuminations, the earthquake resistance performance is good, reliable reliable; the 5, energy conservation, the economy, exempts the maintenance; 6, dynamic color controls, light and shade adjustable, three primary colors LED illumination combinations may use PWM to realize the color change; 7, Shenzhen LED the display monitor LED illumination has the very strong illumination directivity, the luminous flux use factor is high, and the volume is small, easy lamps and lanterns outward appearance design and light intensity distributed control; 8th, the LED illumination may use the direct-current low ...
Semantic Scholar extracted view of [Additive effect of ultraviolet rays and triethylene glycol in air disinfection]. by L B Grun
Because Ultraviolet Rays have higher wavelengths than the visual light spectrum. Does that mean that Einsteins wrong, or did I miss something and am ...
The incidence of BCCs increases with age and with no sex predilection.10 However, in our study there were more women than men in all age categories except for those younger than 30 years (one young man affected and no women). The higher presence of women in our study is only partly explained by the demographics in our area.. The spectral sensitivity of the polysulphone film is restricted to wavelengths below 330 nm and consequently measures mainly erythema-producing UVB. The action spectrum for development of BCC is not known. However, the values at the different sites indicate the UVR exposure at that location and there is no reason to believe that different UV wavelengths should be differently distributed.. Sliney11 discussed the difficulties in estimating ocular exposure to UVR. Clearness of the sky, time of the day, time of the year, latitude, altitude, ground reflectance are some of the variables that influence ambient UVR. The fraction of ambient UVR that affects the skin of the eyelids ...
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Ultraviolet ray absorbent colored glass for buildings and vehicles, which consists essentially of from 65 to 75 wt % of SiO2, from 0.1 to 5.0 wt % of Al2 O3 , from 10 to 18 wt % of Na2 O, from 0 to 5 wt % of K2 O, from 5 to 15 wt % of CaO, from 1 to 6 wt % of MgO, from 0.05 to 1.0 wt % of SO3, from 0.08 to 0.20 wt % of vanadium as calculated as V2 O5, from 0.36 to 0.65 wt % of MnO2, from 0 to 0.0020 wt % of CoO and from 0.06 to 0.18 wt % of iron as calculated as Fe2 O3, wherein from 0 to 10 wt % of the total iron content is FeO.
UV radiation causes several forms of DNA damage; the most prominent of these are cyclobutane pyrimidine dimers (CPDs) and 6-4 pyrimidine-photoproducts (6-4 PPs). Nucleotide excision repair (NER) is a repair process that repairs these DNA lesions. Defects in the NER pathway lead to cancer-related diseases such as xeroderma pigmentosum (XP) that is caused by a defect in the XPA to XPG genes that are involved in the NER pathway. To investigate protein recruitment to chromatin after DNA damage, SV40 minichromosomes containing pyrimidine-rich DNA were established to create a tool with high sensitivity to UV for in vivo studies. Using this tool these findings suggest that p54nrb, which exhibits multi-functional characteristics in a variety of cellular processes, including DNA and RNA binding, nuclear RNA processing and regulation of transcription, is a novel protein putatively involved in UV DNA damage response. The objective of this study was to gain a better insight into the mechanism(s) by which ...
Age spots and blemishes are a group of skin-aging pigmented skin diseases that usually appear in faces chronically exposed to ultraviolet rays. Blemishes appear as marks after sudden exposure to the sun, or as dermatitis, folliculitis and external injuries. Age spots, which appear as a phenomenon of skin-aging problems, look uneven mantises or appear as brown, flat, and round specks. They are caused by excessively thickly growing epidermis and deposits of pigment. The ultraviolet rays begin in spring, become strongest in summer and weaken in winter. As a result, freckles and blemishes also seriously appear in spring and summer and may be eased in winter. In addition to getting treatment, it is important to prevent the skin from becoming dark by blocking ultraviolet rays. ...
(1) x 62mm UV Protection Filter- UV-protection filter for Canon and Nikon lenses will provide basic reduction of ultraviolet light, eliminating the hazy, foggy,
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Kripke, M L. and Fidler, I J., "Enhanced experimental metastasis of ultraviolet light-induced fibrosarcomas in ultraviolet light-irradiated syngeneic mice." (1980). Subject Strain Bibliography 1980. 2588 ...
Proficiency in the Kemetic language isnt needed to comprehend the message being displayed in the above illustration, it is quite obvious. Clearly, these ancient Africans are telling us here that they understood that the same relationship that the plants have with our Sun is equally shared with us. We cannot separate ourselves from nature, for nature is not just our environment, we are nature itself. If this divine agreement, understanding, and obligation are violated the consequences will be severe, like what we are facing today due to our anti-Sun ways of life. Some people are adversely affected by ultraviolet (UV) rays, while others need them to obtain optimal health. Being affected by something doesnt automatically make it bad for everyone else; neither does it make it bad in general. The human biology is a microcosmic Sun; Melanin (eumelanin) is a physical embodiment of natural light and all of its components, including the ultraviolet range. Contrary to common beliefs, ultraviolet ...
The influence of enhanced UV-B radiation (280-320 nm) on wheat ( Triticum aestivumcv. Florida 301) yield, and disease incidence and severity was investigated for two growing seasons under field...
Precis of the Global Panel Solar Simulator Market 2017 Research Report Explore Professional Survey, Market Professional, and more!. The market research report provides a detailed analysis and data about the Panel Solar Simulator market statistical study, the key players, growth dynamics, and geographical analysis. The report provides the information concerning the factors that impel the growth of the Panel Solar Simulator global industry. The Panel Solar Simulator market constitute of the leading groups which play a vital role in the product sales, manufacturing, production, distribution of the products in order to meet the supply and demand chain. A detailed study of the global market share of the past and the future along with the predictable forecast trends is also mentioned in the present report.. ...
Elevated levels of UV-B radiation will have many direct and indirect effects on plants (Fig. 3). Even present-day levels of UV-B radiation affect the growth and development of plants. The direct effects of UV-B radiation on plant cells are mostly damaging, because UV-B photons have enough energy to create lesions in important UV-B-absorbing biomolecules such as nucleic acids and proteins. It is known that the photoproducts of DNA formed by UV-B radiation, cyclobutane pyrimidine dimers and pyrimidine (6-4) pyrimidone and (6-4) photoproducts, are all toxic and mutagenic. In addition, the altered DNA and RNA structures may interfere with transcription and replication; and therefore protein synthesis may be slowed down during UV-B stress. In order to avoid the effects of DNA damage, plants have efficient systems for DNA repair, including photoreactivation and excision repair, which are involved in restoring the structure of genetic material during exposure to UV-B radiation. However, the indirect ...
The aim of the present work was to evaluate the antioxidant and photoprotective effect of blanch water (BW), a byproduct of the almond processing industry. The polyphenolic content of a BW extract, the level of proanthocyanidins and the vanillin index determination were determined. The antioxidant activity and the radical scavenging activity of the BW were evaluated by a range of in vitro tests. The in vivo photoprotective effect was investigated using a formulation containing 2% of the BW extract on skin erythema induced by acute UV-B exposure in twelve volunteers. Results confirmed the presence of added-value antioxidant compounds in the industrial BW extract, and the most representative compounds were naringenin-7-O-glucoside and kaempferol-7-O-rutinoside. The proanthocyanidin content was 71.84 ± 5.21 cyanidin equivalents/g of BW extract. The good antiradical activity of the BW extract was demonstrated in both the DPPH• test and in the Reducing Power test. The percentage inhibition of erythema
Required for DNA repair. Binds to DDB1 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also appears to function as the substrate recognition module for the DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex DDB1-CUL4-ROC1 (also known as CUL4-DDB-ROC1 and CUL4-DDB-RBX1). The DDB1-CUL4-ROC1 complex may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair. The DDB1-CUL4-ROC1 complex also ubiquitinates XPC, which may enhance DNA-binding by XPC and promote NER. Isoform D1 and isoform D2 inhibit UV-damaged DNA repair ...
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In the stratosphere, ozone is created primarily by ultraviolet radiation. When high-energy ultraviolet rays strike ordinary oxygen molecules (O2), they split the molecule into two single oxygen atoms, known as atomic oxygen. A freed oxygen atom then combines with another oxygen molecule to form a molecule of ozone. There is so much oxygen in our atmosphere, that these high-energy ultraviolet rays are completely absorbed in the stratosphere.
Collagen is the main protein of connective tissue. It has great tensile strength, and is the main component of ligaments and tendons. It is responsible for
The insulin-like growth factor-1 (IGF-1) and its downstream effector Akt have been documented as survival factors in response to a variety of stress signals. In this study, we show that IGF-1 activates p21 protein expression in a p53-dependent manner. Inhibition of PI-3 kinase or ectopic expression of a dominant-negative Akt blocks the effect of IGF-1 on the upregulation of p21 expression. In addition, IGF-1 prevents the UV irradiation-mediated suppression of p21 and MDM2 expression. Furthermore, p21 is important for IGF-1-mediated cell survival upon UV irradiation. Taken together, these data indicate that IGF-1 may activate p21 in executing its survival function upon genotoxic insults.. ...
Lysates of HeLa cells treated with UV or untreated cells for use as controls in western blotting to analyze UV-induced DNA damage and/or apoptosis.
Involvement of MIF in Basement Membrane Damage in Chronically UVB-Exposed Skin in Mice. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
UV system : The Ultraviolet rays are a strong disinfectant. Ultraviolet rays damage the cells of microorganisms by destroying them instantly.. Chloroxym : Sodium hypochlorite generator. The only requirements for our generator to work are a supply of salt, water and electricity. [see the website ] ...
... the monitoring of uv sources is an important precautionary measure to avoid health hazards when handling short-wave radiation. in the case of water treatment thorough monitoring is even prescribed
We propose that nanophase iron-oxide-bearing materials provided important niches for ancient photosynthetic microbes on the Earth that ultimately led to the oxygenation of the Earths atmosphere and the formation of iron-oxide deposits. Atmospheric oxygen and ozone attenuate ultraviolet radiation on the Earth today providing substantial protection for photosynthetic organisms. With ultraviolet radiation fluxes likely to have been even higher on the early Earth than today, accessing solar radiation was particularly risky for early organisms. Yet, we know that photosynthesis arose early and played a critical role in subsequent evolution. Of primary importance was protection below 290 nm, where peak nucleic acid (~260 nm) and protein (~280 nm) absorptions occur. Nanophase ferric oxide/oxyhydroxide minerals absorb, and thus block, the lethal ultraviolet radiation, while transmitting light through much of the visible and near-infrared regions of interest to photosynthesis (400 to 1100 nm). ...
Ultraviolet Blood Irradiation is often referred to as UVBI or photoluminescence. UVBI involves drawing a small amount of blood from a person, adding an anticoagulant to keep it from clotting, exposing the blood to ultraviolet light at a specific frequency as it passes through a sterile crystal tube (cuvette) in a closed, airtight circuit, and immediately administering the blood that has been irradiated or illuminated by the ultraviolet light back into the same person by intravenous infusion at the same place in the vein from which it had been drawn. Ultraviolet Blood Irradiation is a tested and proven therapy that is safe and effective for a wide range of health problems with virtually no side effects when performed correctly. It is common knowledge that, for many years, ultraviolet light has been used for disinfection. Exposing blood to ultraviolet light also kills bacteria, viruses and fungi in the blood that is exposed to UV light and when that UV irradiated blood is reintroduced into the ...
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New York, NY (UPDATED September 1, 2015) - Ultraviolet radiation-emitting nail lamps have become a regular part of most trips to the nail salon, causing many patrons to question manicure safety. These lamps are typically used to speed-dry regular manicures, and they are actually necessary to set gel manicures. Some nail lamps are called "UV" lamps, and some are called LED lamps, but both emit UV radiation. They predominantly produce UVA rays, which have been linked to both premature skin aging and skin cancer. However, even the most intense of these devices presents only a moderate UV risk - a far lower risk than that presented by UV tanning devices. To play it safe with gel manicures, The Skin Cancer Foundation recommends applying a broad spectrum (UVA/UVB) sunscreen to hands 20 minutes prior to UV light exposure. If getting a regular manicure, the safest bet is to allow nails to air-dry naturally, avoiding the drying lamps altogether. Remember, all nail lamps produce UV radiation. --Skin ...
Dr. Kira responded: Maybe. Some studies have shown a link between cataracts and sunlight exposure but the cornea absorbs most of the uv. Regardless, uv protection is a good thing to have and is incorporated into most |a href="/topics/glasses" track_data="{
Suzuki, M.; Nakabayashi, R.; Ogata, Y.; Sakurai, N.; Tokimatsu, T.; Goto, S.; Suzuki, M.; Jasinski, M.; Martinoia, E.; Otagaki, S.; Matsumoto, S.; Saito, K.; Shiratake, K., Multi omics in grape berry skin revealed specific induction of stilbene synthetic pathway by UV-C irradiation Plant Physiol. 168, 47-59 (2015) [pubmed ...
Knowing your familys history when it comes to eye disease can really be beneficial to you. The sooner you catch something, the sooner treatment can start to help maintain your eye health longer.. Omega-3 fatty acids are great for excellent eye care. It would be a great idea to make use of foods that contain this nutrient into your diet. Foods such as tuna, salmon, salmon and dark, leafy green vegetables. Get one serving eaten every day you can.. Wearing good sunglasses help keep your eyes protected from UV rays. Too much UV exposure can cause damage to the eyes. Find ones that address UVB rays and UVA rays. You also have the choice of wraparound glasses that protect all possible angles.. Help your eyes healthy by wearing a pair of good quality sunglasses. They can keep your eyes protected from damaging ultraviolet rays. The sunglasses you choose should block all UVA and UVB rays. They also help you reduce any glare. Even with contacts that have UV protection, wearing sunglasses is still ...
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PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Overexposure to UVB radiation not only can cause sunburn but also some forms of skin cancer. However, the degree of redness and eye irritation (which are largely not caused by UVA) do not predict the long-term effects of UV, although they do mirror the direct damage of DNA by ultraviolet.[51]. All bands of UV radiation damage collagen fibers and accelerate aging of the skin. Both UVA and UVB destroy vitamin A in skin, which may cause further damage.[52]. UVB radiation can cause direct DNA damage.[53] This cancer connection is one reason for concern about ozone depletion and the ozone hole. The most deadly form of skin cancer, malignant melanoma, is mostly caused by DNA damage independent from UVA radiation. This can be seen from the absence of a direct UV signature mutation in 92% of all melanoma.[54] Occasional overexposure and sunburn are probably greater risk factors for melanoma than long-term moderate exposure.[55] UVC is the highest-energy, most-dangerous type of ultraviolet radiation, and ...
In CsA-treated transplant recipients, immunosuppression has been widely accepted as the major cause of increased skin carcinogenesis. However, consistent with epidemiologic data supporting the critical role of UV radiation, we have used controlled laboratory in vitro and in vivo models to show that CsA impairs the DNA repair and DDR in the response of keratinocytes to UVB. As a consequence, in immunocompromised nude mice, CsA increased skin tumorigenesis in which UVB damage and PI3K/AKT activation are required. At the molecular level, CsA downregulates the DNA repair protein XPC and upregulates the CsA-binding partner CypA through activating the PI3K/AKT pathway. Blocking UVB damage or inhibiting the PI3K/AKT pathway prevents CsA-sensitized skin tumorigenesis. Our findings further support a cell-autonomous action of CsA on skin tumorigenesis.. Following UVB damage, CsA inhibited UVB-induced DNA damage repair through suppressing XPC transcription. Consistent with recent studies using human ...
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The Earths ecosystems are protected from the dangerous part of the solar ultraviolet (UV) radiation by stratospheric ozone, which absorbs most of the harmful UV wavelengths. Severe depletion of stratospheric ozone has been observed in the Antarctic region, and to a lesser extent in the Arctic and midlatitudes. Concern about the effects of increasing UV radiation on human beings and the natural environment has led to ground based monitoring of UV radiation. In order to achieve high-quality UV time series for scientific analyses, proper quality control (QC) and quality assurance (QA) procedures have to be followed. In this work, practices of QC and QA are developed for Brewer spectroradiometers and NILU-UV multifilter radiometers, which measure in the Arctic and Antarctic regions, respectively. These practices are applicable to other UV instruments as well. The spectral features and the effect of different factors affecting UV radiation were studied for the spectral UV time series at Sodankylä. ...
A quartz monochromator has been used to measure the relative response of several synthetic phosphors in the region of 2200A to 3150A. The deactivating effect of copper and nickel on certain substances is represented graphically. With a vacuum grating spectrograph the response characteristics of zinc silicate and calcium tungstate have been extended to the Schumann ultraviolet region.. © 1939 Optical Society of America. Full Article , PDF Article ...
Ultraviolet (UV) radiation comprising the wavelength range from 100 nm to 400 nm is the most energetic part of optical radiation. It adjoins directly to the range of ionising radiation. In the short wavelength range UV radiation can have similar effects as ionising radiation. According to different biological effects UV radiation is subdivided into three wavelength ranges: UV-A radiation (400 - 315 nm), UV-B radiation (315 - 280 nm) and UV-C radiation (280 - 100 nm). UV radiation is not visible for humans and cannot be perceived by other sense organs. Depending on wavelength and intensity UV radiation can produce numerous health effects mainly to eye and skin.. ...
There are mainly three types of skin cancer namely: 1.BASAL-CELL CARINOMA 2.SQUAMOUS-CELL CARCINOMA 3.MELANOMA The malignancies of the skin remain restricted in the epidermis, mostly due to invisible ultraviolet rays emitted by the sun. The ozone gas present in the air absorb most of the suns radiation, so that only a small percentage of ultraviolet radiation of longest wave length (UVA) and ultraviolet radiation of shortest wave length (DYB) reaches the earths surface. The UVB rays are known to burn the skin more easily and have cancer-causing potential. The disease usually occurs as a small, pearly bump on the face, neck, hands or the nose. If left untreated, the basel-cell carcinomas can crust, bleed or ulcerate. These tumors take months or years to grow_ to half an inch in diameter. They root under the skin, causing disfigurement and damage underlying bone, cartilage and muscle. It has a cure rate of better than ninety-nine per cent if detected early. A dermatologist (a physician ...
Endothelium derived nitric oxide (NO) regulates vascular tone and blood pressure in man. NO also inhibits platelet aggregation and mediates a variety of beneficial anti-inflammatory and repair mechanisms. NO may also be a mediator in the release of the endogenous fibrinolytic factor, tissue-plasminogen activating factor (t-PA) from the endothelium.1 Via these actions it plays a very important role in protection of the vasculature from atherothrombosis and clinical sequelae such as myocardial infarction and stroke.. Visible and ultraviolet (UV) light relax vascular smooth muscles by producing NO in a phenomenon known as photorelaxation.2 The investigators have demonstrated significant stores of pre-formed, bound NO and other nitrosospecies in human skin, which are rapidly released upon exposure to UVA.3 The investigators have demonstrated recently that serum nitrite and nitroso-species are increased after standing in a UVA phototherapy cabinet and that local UVA exposure is associated with ...
What is ultraviolet radiation? What are some sources of ultraviolet radiation? What are some health effects of exposure to UV radiation?
A method of inactivating microorganisms such as viruses within a fluid such as a biological fluid is disclosed. The method includes the steps of providing a UV reactor, which may take the form of an elongated generally annular reaction chamber surrounding at least one elongated UV lamp, moving the fluid within the reaction chamber in a primary flow directed along the length of the UV lamp, and inducing a circulating secondary flow within the fluid with the secondary flow being superimposed on the primary flow. As the fluid moves through the reaction chamber in the primary flow, it is circulated repeatedly toward and away from the UV lamp in the circulating secondary flow to provide uniform and controllable exposure of the entire volume of fluid to ultraviolet radiation. Microorganisms such as viruses are thus inactivated while desirable components in the fluid, such as proteins, are preserved without the use of a free radical scavenger.
Cdc48/p97 is an essential ATPase whose role in targeting substrates to the ubiquitin-proteasome system (UPS) remains unclear. Existing models posit that Cdc48 acts upstream of UPS receptors. To address this hypothesis, we examined the association of ubiquitin (Ub) conjugates with 26S proteasomes. Unexpectedly, proteasomes isolated from cdc48 mutants contain high levels of Ub conjugates, and mass spectrometry identified numerous nonproteasomal proteins, including Rpb1, the largest subunit of RNA Pol II. UV-induced turnover of Rpb1 depends upon Cdc48-Ufd1-Npl4, Ubx4, and the uncharacterized adaptor Ubx5. Ubiquitinated Rpb1, proteasomes, and Cdc48 accumulate on chromatin in UV-treated wild-type cells, and the former two accumulate to higher levels in mutant cells, suggesting that degradation of Rpb1 is facilitated by Cdc48 at sites of stalled transcription. These data reveal an intimate coupling of function between proteasomes and Cdc48 that we suggest is necessary to sustain processive degradation of
Skin cancer is the most frequent type of cancer in the Western World, and the strongest known risk factor is exposure to UV light. The high-energy UV-B and UV-C light only constitute a small fraction of the total UV light in sunlight. UV-B and UV-C light induce pyrimidine dimers that are repaired by nucleotide excision repair. The majority of the UV light in sunlight is UV-A light. UV-A light is absorbed in keratinocytes, giving rise to formation of reactive oxygen species, among them hydrogen peroxide (1). Hydrogen peroxide accumulation may directly or through reaction products, such as hydroxyl radicals, cause oxidative stress and oxidative DNA damage. Glutathione peroxidase is part of the defense system that neutralizes hydrogen peroxide. Heterozygous and homozygous carriers of the variant allele of the GPX Pro198Leu polymorphism are at 1.8-fold (95% confidence interval 1.2-2.8) and 2.3-fold (95% confidence interval 1.3-3.8) higher risk of lung cancer, respectively (2). Homozygous carriers of ...
Solar simulators provide a broadband spectrum close to that of the sun from the UV to the IR. The main part of the solar simulator is a xenon arc lamp th...
2) Keep your sunglasses handy. UV protection isnt just for your skin; UV rays can cause vision issues, too. And even in cloudy cities like Pittsburgh, UV protection is a year long necessity. So any time you leave your house this season, make sure a pair of sunglasses is in your bag, pocket, car - wherever you need to keep them to ensure that your eyes get the UV protection they need.. 3) Take out contacts at the end of the day (as well as when you nap).While contacts are a convenient vision aid for many, improperly wearing and using them is a huge eye health risk. Long-term wear of contacts deprives the eye of oxygen that it needs to stay healthy, and can increase your risk of developing eye infections; overnight use also often increases the risk of developing a corneal ulcer. So even if your contacts are approved for overnight use, youre better off removing them and properly cleaning them if you plan on getting any amount of shut eye - its better to be safe than sorry!. 4) Never sleep in eye ...
Now that the sun has finally got his hat on, its important not to overlook eye protection whether you are staying at home or going on holiday.
Abstract. Erythemaly weighted UV and total UV-A irradiance measured at the ALOMAR (Arctic Lidar Observatory for Middle Atmosphere Research; 69° N, 16° E) in June 2007 by two Kipp & Zonen UV broadband meters type, UV-S-EA-T, are examined. One unit is mounted on rotating vertical plane and the other is permanently fixed horizontally. The UV broadband meters measure simultaneously to compare UV irradiances on vertical and horizontal planes. The entire range of such relative exposure variations during clear-sky and overcast conditions over ALOMAR in the period March-June 2007 is examined using STAR and Radonic1 model (developed at the Meteorological Institute, University of Munich) for various action spectra: erythema, UV-A, and vitamin D3. The model and observations support that the daily means of relative exposures are quite stable, i.e., vary within the range 0.4-0.6 with the mean around 0.5 when the averaged intra-day, day-to-day, and seasonal changes of the relative erythemal exposures are ...
The Exo Terra Explorarium provides optimal ventilation - very important for a number of reptile species (e.g. Chameleons). An incandescent light fixture (e.g. Exo Terras Glow Light) can be easily mounted inside the enclosure. The nylon mesh allows ultraviolet rays from fluorescent UVB lights to penetrate deep inside the enclosure. The Explorarium can also be positioned in front of windows, without the risk of overheating, as is common with glass terrariums. The included Flextray can be used to hold substrate and/or contain liquids inside the enclosure ...
Some traits can be inherited through genetics. Some of these genetic traits like fair hair, fair skin and blue eyes do not cause cancer but may make people more susceptible to some kinds of carcinogens like ultraviolet (UV) light. People with these traits have less melanin (a pigment found in skin that absorbs UV) which makes them more susceptible to skin damage caused by ultraviolet radiation. Some studies suggest that people with low melanin may have developed this trait in order to adapt to areas with low UV due to northern location and dense cloud cover. In order for the skin to synthesize Vitamin D in low UV areas, skin must be able to absorb ultraviolet light and must therefore have less UV absorbing melanin. Now that people whose ancestors had adapted to living in low UV areas are living in high UV areas, people with these traits need to be particularly careful to reduce overexposure to UV rays.. For students continuing their science education beyond the standards, what they know and are ...
Exposure to ultraviolet (UV) irradiation can often be harmful to DNA, causing damage and mutations. Researchers have just uncovered the mechanism by which DNA protects itself from UV light, preventing harmful changes in the genetic code.. According to research conducted at Kiel University in Germany, in collaboration with The University of Bristol in the UK, cells funnel the energy from UV light into an innocuous reaction which protects DNA from damage. The results of the study were published in the journal, Angewandte Chemie (Applied Chemistry).. DNA consists of four nitrogenous bases: cytosine, guanine, adenine and thymine. The researchers used a tool called femtosecond spectroscopy - a technique where extremely short blasts of light are directed at the guanine-cytosine base pairs - to determine the effect of UV light on the DNA.. The researchers used that particularly fast method of spectroscopy to monitor the molecular changes, because the DNAs reaction to UV light occurred within a few ...
Ultraviolet rays are an invisible form of radiation streaming from the sun. There are three ranges of UV ray lengths: UVA, UVB, and UVC. UVA is the most abundant; this form can penetrate past the top layer of skin. Researchers believe that UVA can damage the bodys connective tissue, boosting a persons risk for developing skin cancer. Much of the UVB rays are absorbed by the ozone layer in the earths atmosphere. The UVB rays that do reach your skin can be damaging, even though they dont penetrate as deeply as UVA. UVC is very hazardous to the skin, but fortunately, all of these rays are absorbed by the ozone layer ...
Although the warmth of the summer sun is greatly enjoyable, it can cause immense damage to our bodies. · We are all aware of the damage caused to our skin by UV rays and that the best solution is to wear a high SPF sunscreen and cover any areas of our body that are exposed to direct sunlight whenever possible, but did you know how damaging sunlight can be to our eyes? · Eye exposure to ultraviolet rays can lead to eye damage that includes vision impairment or even vision loss. o Extensive or intense exposure to UV rays can cause sunburn on the surface of your eye. o Excessive exposure to UV rays is connected to the development of many eye conditions including cataracts and age-related macular degeneration. · Protection options for eyes include: o Wearing sunglasses that block out 99 to 100 percent of UV-A and UV-B rays o Wearing a wide brimmed hat that keeps rays out of your eyes. This tip is brought to you by St. Marys Regional Center for Cancer and Blood Disorders ...
The major finding of the current study is that overexpression of a PKCδKD mutant protects INS-1 cells against apoptosis induced by both STZ and IL-1β. The corresponding PKCα mutant was without effect. Identical KD mutants have been widely used in functional studies to inhibit endogenous PKC in an isozyme-specific manner (12,31-34,36). The current results suggest for the first time that PKCδ plays a specific and important role in mediating apoptosis in pancreatic β-cells. Our findings also confirm and extend earlier studies in which pharmacological inhibitors of PKCδ inhibited spontaneous apoptosis in neutrophils (21), as well as the cytotoxic effects of ultraviolet radiation on keratinocytes (19) and of etoposide on salivary cells (20). However, the specificity of the pharmacological agents used in these earlier studies, and especially the use of rottlerin as a PKCδ inhibitor, is now open to doubt (37). Therefore, molecular approaches, such as those used here, are increasingly the methods ...
Article UV-radiation 1983-2003 measured at Norrköping, Sweden. Total ozone has been monitored with high accuracy at many sites for a relative long period of time. This is not the case for UV. The main reason is that UV is difficult to measure accurat...
Ultraviolet rays (UVR) are sneaky. Not only can they cause skin cancer and visible signs of aging, theyre also very good at finding you. They can bounce off water, off sand, and they can penetrate glass. Which means that even if youre inside your car or house, if youre sitting next to a window with sunlight streaming in, youre at risk for UV damage. Window film is an increasingly effective solution, offering substantial indoor protection by blocking up to 99.9 percent of UVA radiation.. ...
Youd be surprised. Theres a difference between preventing sunburn and preventing other types of skin damage. Some sunscreens can do both, but others cant. Sun damage, as you may have heard, is caused by exposure to ultraviolet rays, or UV rays.
The Genetics Society of America (GSA), founded in 1931, is the professional membership organization for scientific researchers and educators in the field of genetics. Our members work to advance knowledge in the basic mechanisms of inheritance, from the molecular to the population level.. Online ISSN: 1943-2631. ...
Ultraviolet (UV) radiation comprising the wavelength range from 100 nm to 400 nm is the most energetic part of optical radiation. It adjoins directly to the range of ionising radiation. In the short wavelength range UV radiation can have similar effects as ionising radiation. According to different biological effects UV radiation is subdivided into three wavelength ranges: UV-A radiation (400 - 315 nm), UV-B radiation (315 - 280 nm) and UV-C radiation (280 - 100 nm). UV radiation is not visible for humans and cannot be perceived by other sense organs. Depending on wavelength and intensity UV radiation can produce numerous health effects mainly to eye and skin.. ...
Cardiovascular disease, often associated with high blood pressure, accounts for 30 per cent of deaths globally each year. Blood pressure and cardiovascular disease are known to vary according to season and latitude, with higher levels observed in winter and in countries further from the equator, where ultraviolet radiation from the sun is lower. During the study, the skin of 24 healthy individuals was exposed to ultraviolet (UVA) light from tanning lamps for two sessions of 20 minutes each. In one session, the volunteers were exposed to both the UVA rays and the heat of the lamps. In another, the UV rays were blocked so that only the heat of the lamps affected the skin.. The results suggest that UVA exposure dilates blood vessels, significantly lowers blood pressure, and alters NO metabolite levels in the circulation, without changing vitamin D levels. Further experiments indicate that pre-formed stores of NO in the upper skin layers are involved in mediating these effects. The data are ...
Quit smoking or never start. Research has linked smoking to an increased risk of developing age-related macular degeneration, cataracts and optic nerve damage, all of which can lead to blindness.. • Be cool and wear your shades. Sunglasses protect your eyes from the suns ultraviolet rays. Look for ones that block out 99 to 100 percent of both UV-A and UV-B radiation.. • Give your eyes a rest. If you spend a lot of time at the computer or focusing on any one thing, you sometimes forget to blink and your eyes can get fatigued. Try the 20-20-20 rule: Every 20 minutes, look away about 20 feet in front of you for 20 seconds. This can help reduce eyestrain.. • Clean your hands and your contact lenses-properly. Always wash your hands thoroughly before putting in or taking out your contact lenses. Disinfect contact lenses as instructed and replace them as appropriate.. To learn more, visit www.nei.nih.gov/healthyeyes.. North American Precis Syndicate, Inc.. ...
TY - JOUR. T1 - A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functions. AU - Inga, Alberto. AU - Nahari, Dorit. AU - Velasco-Miguel, Susana. AU - Friedberg, Errol C.. AU - Resnick, Michael A.. PY - 2002/8/22. Y1 - 2002/8/22. N2 - A mutation in codon 122 of the mouse p53 gene resulting in a T to L amino acid substitution (T122→L) is frequently associated with skin cancer in UV-irradiated mice that are both homozygous mutant for the nucleotide excision repair (NER) gene Xpc (Xpc-/-) and hemizygous mutant for the p53 gene. We investigated the functional consequences of the mouse T122→L mutation when expressed either in mammalian cells or in the yeast Saccharomyces cerevisiae. Similar to a non-functional allele, high expression of the T122→L allele in p53-/- mouse embryo fibroblasts and human Saos-2 cells failed to suppress growth. However, the T122→L mutant p53 showed wild-type transactivation levels with Bax and MDM2 promoters when ...
TY - JOUR. T1 - ADA-07 suppresses solar ultraviolet-induced skin carcinogenesis by directly inhibiting TOPK. AU - Gao, Ge. AU - Zhang, Tianshun. AU - Wang, Qiushi. AU - Reddy, Kanamata. AU - Chen, Hanyong. AU - Yao, Ke. AU - Wang, Keke. AU - Roh, Eunmiri. AU - Zykova, Tatyana. AU - Ma, Weiya. AU - Ryu, Joohyun. AU - Curiel, Clara N. AU - Alberts, David S. AU - Dickinson, Sally E. AU - Bode, Ann M.. AU - Xing, Ying. AU - Dong, Zigang. PY - 2017/9/1. Y1 - 2017/9/1. N2 - Cumulative exposure to solar ultraviolet (SUV) irradiation is regarded as the major etiologic factor in the development of skin cancer. The activation of the MAPK cascades occurs rapidly and is vital in the regulation of SUV-induced cellular responses. The T-LAK cell-originated protein kinase (TOPK), an upstream activator of MAPKs, is heavily involved in inflammation, DNA damage, and tumor development. However, the chemopreventive and therapeutic effects of specific TOPK inhibitors in SUV-induced skin cancer have not yet been ...
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features superior eye and UV protection. The Airwear polycarbonate material helps protect against UV transmission on the front side of the lens, while Crizal Kids UV no-glare technology reduces UV reflections off the backside of the lens. Additionally, the lenses offer an Eye-Sun Protection Factor (E-SPF®) of 25, which means young patients eyes are 25 times more protected than wearing no lenses at all.. "Essilor strongly believes in the importance of offering children the safest, most comfortable vision options to ensure quality of life and to enhance their education and learning," said Howard Purcell, O.D., FAAO, senior vice president of customer development, Essilor of America. "We are pleased to offer now to children the same superior clarity of vision benefits and the additional UV protection that adults receive from Crizal lenses.". Crizal Kids UV lenses are designed for children ages 5 to 12 years old and offer Essilors Broad Spectrum Technology™ coatings on safe, shatterproof Airwear ...
July is National Ultraviolet Safety Month so it is the perfect time for the Ipswich Department of Public Health to help raise awareness of the risks of sun damage and spread the message of sun safety.Ultraviolet rays from the sun are the main cause of skin cancer. Everyone is at risk for skin cancer, but the risk is greatest for people with white or light-colored skin with freckles, blond or red hair and blue or green eyes. Also, people who spend a lot of time outdoors are more likely to get
IN a letter on this subject published in NATURE, May 13, I showed that sodium vapour, stimulated by the second line of the principal series at wave-length 3303 in the ultra-violet, fluoresces with emission of the D line, which is the first member of the principal series.
In the perennial clash between man and microbe, ultraviolet light has emerged as one of mans powerful tools against many pathogens. Although ultraviolet light can wipe out several germs, the exact mechanisms that orchestrate the radiations damaging action have long been elusive. Texas A&M scientists can now explain how it works
Sunglasses help you in two important ways. They filter light and they protect your eyes from damaging UV rays. Mounting evidence shows that exposure to UV rays
There are three main types of UV radiation from the sun. The most dangerous UV-C rays are completely absorbed by the ozone layer. The remaining two types, UV-A and UV-B, each have a different effect on the human body.. UV-A (400 - 315 nanometers). UV-A radiation does not cause sunburn. Because of this, it was previously discounted as a potential cause of skin cancer, but new research has proven the link between UV-A and skin cancer.. The long waves of UV-A radiation penetrate the skin more deeply into the lower layers, where they produce a deep tan. They damage the connective tissue in these layers, causing premature ageing, wrinkles and loss of skin tone.. UV-B (315 - 280 nanometers). Most of the UV-B radiation that reaches the Earths atmosphere is intercepted by the ozone layer. However, depletion in this layer has led to an increase in UV-B rays reaching ground level.. The short waves of UV-B radiation penetrate the upper layers of the skin, damaging DNA and causing it to tan as an attempt ...
There are three main types of UV radiation from the sun. The most dangerous UV-C rays are completely absorbed by the ozone layer. The remaining two types, UV-A and UV-B, each have a different effect on the human body.. UV-A (400 - 315 nanometers). UV-A radiation does not cause sunburn. Because of this, it was previously discounted as a potential cause of skin cancer, but new research has proven the link between UV-A and skin cancer.. The long waves of UV-A radiation penetrate the skin more deeply into the lower layers, where they produce a deep tan. They damage the connective tissue in these layers, causing premature ageing, wrinkles and loss of skin tone.. UV-B (315 - 280 nanometers). Most of the UV-B radiation that reaches the Earths atmosphere is intercepted by the ozone layer. However, depletion in this layer has led to an increase in UV-B rays reaching ground level.. The short waves of UV-B radiation penetrate the upper layers of the skin, damaging DNA and causing it to tan as an attempt ...
Principal Investigator:MUKAI Yuzuru, Project Period (FY):1997 - 1999, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:林学
Strid Ake , Chow W.S. , Anderson Jan M. Plant and cell physiology 37(1), 61-67, 1996 CiNii 外部リンク 機関リポジトリ 参考文献23件 被引用文献2件 ...
There is a common myth that UV radiation brings only harm to our health. But that is not the case always, the benefits of ultraviolet radiation ranges from vitamin D production to sun tanning
Vitamin D is a hormone produced by human skin in response to the Sun and to other sources of ultraviolet-B (UVB) light. Our vitamin D blood levels are lower in the winter due to the lower angle of the sun and the resulting reduced amount of natural UVB light. Blood levels are "highest in late […]. View Post ...
The Ultra-Violet Differential Optical Adsorption Spectrometer is a fixed continuous emissions monitor. The system provides real-time multi-gas measurements.
Besides damaging your skin, the summer suns ultraviolet rays can also hurt your eyes. Over time, exposure to UV rays can can raise the risk for cataracts and other eye problems. Take care by wearing proper sunglasses.
shrinks from 150 to 40 nanometers.. As anyone who has played with a powerful laser or just suffered a bad sunburn can attest, light has an impressive power to physically change objects. And now we know that light can make nanoparticles expand and contract like miniature Hoberman Spheres. MIT and Harvard researchers engineered nanoparticles that shrink to less than a third of their original size when exposed to ultraviolet rays; in the darkness or under visible light, they open back up to their more stable, larger size.. Nanoparticles have been touted as an effective way to deliver cancer-killing drugs straight to tumors without harming healthy cells in the process. But the structure of a tumor can block all but the smallest particles-those less than 100 nanometers (billionths of a meter)-from penetrating to the cancers heart. To deliver drugs to the entire tumor, the researchers suggest that the particles could be deployed while UV light keeps them in their smaller form, about 40 nanometers. ...
Wed of course do anything to stay young, however the unfortunate truth is; ageing is unstoppable. Nevertheless, there could be ways and means to reduce the effect of it on us. If we identify signs of ageing beforehand itself, such as thinning hair, spots on skin, fine lines and wrinkles, sore feet etc. we could take measures to prevent them, or rather delay the process. So here are such few good habits you could practice.. Stay away from the sun. Sun damage is one of the most common factors that contribute to ageing. It is obvious you cannot avoid going out in broad daylight with our busy lives, however you need to take measures to prevent direct exposure. The ultraviolet rays of the sun will damage the elastic fibers that keep the skin firm and intact, which then causes sagging and wrinkles. It also generates spots on skin which are known as liver spots. The extent of sun damage will differ from person to person according to his or lifetime exposure to sun, skin type etc. Avoid direct ...
It is also important to not only wear sunscreen while out in the sun, but to also wear protective sunglasses. Ultraviolet rays can cause eyes damage, and the incidence of cataracts increase with sun exposure, and corneal sunburn and growths on the surface of the eye are thought to be related to long term sun exposure, according to Smith ...
With summer vacation just starting and the Fourth of July quickly approaching, you may be planning trips to the beach, lazy days in the backyard hammock, and neighborhood barbecues that last well into the evening-so youre going to need plenty of ways to protect yourself from the ultraviolet rays (UV) and heat of the sun! If youre concerned about sun damage such as wrinkles or brown spots-kick-start your sun protection regimen by following these simple tips for healthier, radiant-looking skin all season long!
Provides Water and Filtration Solutions, Large selection of ultraviolet drinking water systems and Pura Whole House Ultraviolet Treatment Systems, reverse osmosis with ultraviolet light and more
Most people living in Australia have a skin type which is not suitable for the intense sun in this country.. Damage to our health caused by the sun (UVA, UVB radiation) is not just about getting sun burnt (red skin). The effect responsible for skin cancer and other health problems is often not felt and may not be seen immediately.. Intense UV radiation causes direct harm to our skin and eyes and other medical conditions can be made worse by UV exposure. UVB causes skin cancer however brief UVB exposure is essential for Vitamin D production. In fact, UVB is crucial for our survival in the absence of other dietary sources of Vitamin D.. UV radiation can be a threat to our life or help to sustain us. It is a matter of getting the balance right!. There is a need for good Sun Safety education. Nature does not adjust to us - we have to adjust to nature! We have to learn, how to live with the conditions given here in Australia or wherever we go.. ...
UNDATED) - Hoosiers welcome the warmer weather and sunshine this time of year.. However, many people will not take precautions against the harmful ultraviolet rays and wear sunscreen. Skin cancer is the number one cancer in America and yet it can be highly preventable. Statistics reveal that melanoma, a form of the disease, takes the life of one American every hour. Today is "Melanoma Monday," the kick-off of may Melanoma Awareness Month. People are encouraged to examine their skin for skin cancer.. ...