O:13:\PanistOpenUrl\:36:{s:10:\\u0000*\u0000openUrl\;N;s:6:\\u0000*\u0000idc\;N;s:6:\\u0000*\u0000fmt\;s:7:\journal\;s:6:\\u0000*\u0000doi\;s:0:\\;s:6:\\u0000*\u0000pii\;s:0:\\;s:7:\\u0000*\u0000pmid\;s:0:\\;s:9:\\u0000*\u0000atitle\;s:87:\CIRCADIAN RHYTHMICITY OF TYROSINE AMINOTRANSFERASE ACTIVITY IN DROSOPHILA MELANOGASTER.\;s:9:\\u0000*\u0000jtitle\;s:0:\\;s:9:\\u0000*\u0000stitle\;s:0:\\;s:7:\\u0000*\u0000date\;s:4:\1977\;s:9:\\u0000*\u0000volume\;s:0:\\;s:8:\\u0000*\u0000issue\;s:0:\\;s:8:\\u0000*\u0000spage\;s:0:\\;s:8:\\u0000*\u0000epage\;s:0:\\;s:8:\\u0000*\u0000pages\;s:0:\\;s:7:\\u0000*\u0000issn\;s:0:\\;s:8:\\u0000*\u0000eissn\;s:0:\\;s:9:\\u0000*\u0000aulast\;s:6:\TAUBER\;s:10:\\u0000*\u0000aufirst\;s:1:\H\;s:9:\\u0000*\u0000auinit\;N;s:10:\\u0000*\u0000auinitm\;N;s:5:\\u0000*\u0000au\;a:2:{i:0;s:8:\TAUBER H\;i:1;s:11:\HARDELAND ...
Flt3 - Fetal Liver Tyrosine Kinase 3. Looking for abbreviations of Flt3? It is Fetal Liver Tyrosine Kinase 3. Fetal Liver Tyrosine Kinase 3 listed as Flt3
Williams Jr., J. N. ; Sreenivasan, A. (1953) The stability and activation of the liver tyrosine oxidase system The Journal of Biological Chemistry, 203 (2). pp. 613-623. ISSN 0021-9258 ...
Jansen, Hans-Michael; Strähle, Uwe; Gloss, Bernd; Stewart, Francis; Schmid, Wolfgang; Boshart, Michael; Miksicek, Richard und Schlitz, Günther (1987): Cooperativity of Glucocorticoid Response Elements Located Far Upstream of the Tyrosine Aminotransferase Gene. In: Cell, Vol. 49, Nr. 1: S. 29-38 [PDF, 1MB] ...
Nitsch, Doris; Ruppert, Siegfried; Kelsey, G. D.; Schedl, A.; Weih, Falk; Stewart, A. F.; Strähle, Uwe; Schmid, Wolfgang; DeVack, Carol; Reik, A.; Boshart, Michael und Schütz, Günther (1991): Hormonal and liver-specific control of expression of the tyrosine aminotransferase gene. In: Cohen, P. und Foulkes, J. G. (Hrsg.): Molecular Aspects of Cellular Regulation. Amsterdam: Elsevier. S. 433-444 [PDF, 1MB] ...
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Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
Ywhaq - Ywhaq (untagged ORF) - Rat tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide (Ywhaq), (10 ug) available for purchase from OriGene - Your Gene Company.
Looking for online definition of tyrosine aminotransferase in the Medical Dictionary? tyrosine aminotransferase explanation free. What is tyrosine aminotransferase? Meaning of tyrosine aminotransferase medical term. What does tyrosine aminotransferase mean?
We previously reported that the administration of dexamethasone to adult male rats significantly induced SULT2 mRNA and protein levels in the liver (Runge-Morris et al., 1996). In primary cultured rat hepatocytes, SULT2 mRNA expression continued to increase as the dexamethasone dose was augmented from 10−8 to 10−5 M (Runge-Morris et al., 1996). These findings contrasted sharply with those obtained for expression of tyrosine aminotransferase, a gene that is regulated via a classical glucocorticoid receptor-mediated mechanism (Shinomiya et al., 1984). In hepatocytes, lower doses of dexamethasone (10−8M compared with 10−5 M) produced more substantial increases in tyrosine aminotransferase mRNA expression, and cotreatment with dexamethasone and the glucocorticoid receptor antagonist RU486 had a greater inhibitory effect on dexamethasone-induced tyrosine aminotransferase than on dexamethasone-induced SULT2 mRNA expression (Runge-Morris et al., 1996). These data implicated the involvement of ...
Fingerprint Dive into the research topics of Organ specificity of glucocorticoid-sensitive tyrosine aminotransferase. Separation from aspartate aminotransferase isoenzymes. Together they form a unique fingerprint. ...
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This study has demonstrated that GC may affect the cytotoxicity of cisplatin in the GR-rich human carcinoma cell line, SiHa. Since GC is commonly co-administered with cisplatin, this influence of GC on cytotoxicity may affect the response to cisplatin treatment in carcinoma patients.. GC mediates its effects by binding to and activation of GR. Activated GR exerts its cellular effect by either transactivating its downstream GRE-containing genes or interacting with other transcriptional factors. In the former transactivation mechanism, GC binds to its cytoplasmic receptor, dimerizes, enters the nucleus, and finally binds to GREs to transactivate the target genes, such as tyrosine aminotransferase and alanine aminotransferase (Beato et al. 1995). However, some major effects of GC, including its anti-inflammatory and immunosuppressive effects, are achieved by regulating genes that do not contain GREs in their promoters (McEwan et al. 1997, Van der Burg et al. 1997, Cato & Wade 1996). This finding ...
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TY - JOUR. T1 - The Influence of Thyroxine and Thiouracil on Rats Fed Excess Tyrosine (34572). AU - Boctor, Amal M.. AU - Rogers, Quinton. AU - Harper, A. E.. PY - 1970/1/1. Y1 - 1970/1/1. N2 - Addition of thiouracil to a high tyrosine diet alleviated signs of tyrosine toxicity in the rat, whereas, daily injections of thyroxine aggravated them. Plasma tyrosine concentration and liver tyrosine transaminase activity were high in rats fed a high tyrosine diet; thyroxine administration increased them further, but depressed slightly the activity of liver p-hydroxyphenylpyruvate hydroxylase.. AB - Addition of thiouracil to a high tyrosine diet alleviated signs of tyrosine toxicity in the rat, whereas, daily injections of thyroxine aggravated them. Plasma tyrosine concentration and liver tyrosine transaminase activity were high in rats fed a high tyrosine diet; thyroxine administration increased them further, but depressed slightly the activity of liver p-hydroxyphenylpyruvate hydroxylase.. UR - ...
Citrate accumulation and secretion are physiological functions of the normal prostate gland in most species. Prolactin (PRL) stimulates citrate accumulation in the rat lateral prostate (LP) and pig prostate by increasing the expression of mitochondrial aspartate aminotransferase (mAAT), the enzyme that catalyzes aspartate transamination. In the present studies, we established the role of PRL and the phorbol ester 12-O-tetra-decanoylphorbol 13-acetate (TPA) in the regulation of mAAT in LNCaP and PC-3 cells. We isolated total RNA from the cells and hybridize it with a mAAT cDNA. Next, we assayed protein kinase C (PKC) activity and expression in PRL and TPA treated prostate cells. We, then determined the effect of PRL and TPA on gene transcription using a mAAT-chloramphenicol acetyltransferase (CAT) reporter gene construct, transiently transfected into PC-3 cells. A fragment of the 5{dollar}\sp\prime{dollar} gene region containing putative TPA response elements (TRE) was cloned into the ...
TY - JOUR. T1 - Acute renal failure after treatment with sunitinib in a patient with multiple myeloma. AU - Leung, Nelson. AU - Saucier, Nathan A.. AU - Zeldenrust, Steven R.. AU - Gunderson, Heidi D.. AU - Cornell, Lynn D.. PY - 2009/8. Y1 - 2009/8. N2 - Sunitinib is a multiple tyrosine kinase receptors inhibitor that is approved for the treatment of advanced renal cell carcinoma. Amongst its targets are fetal liver tyrosine kinase receptor 3 (FLT 3) and vascular endothelial growth factor receptor (VEGFR). Renal toxicity has not been reported from the trials, but several patients have been reported to develop a pre-eclampsia-like syndrome. We report the first case of acute tubular necrosis in a patient with multiple myeloma following treatment with sunitinib.. AB - Sunitinib is a multiple tyrosine kinase receptors inhibitor that is approved for the treatment of advanced renal cell carcinoma. Amongst its targets are fetal liver tyrosine kinase receptor 3 (FLT 3) and vascular endothelial growth ...
Because of the interest in the relationship between cholesteryl ester (CE) accumulation and atherosclerosis, we have attempted to select an easily grown tissue culture cell which accumulates CE when...
Phosphatidylcholine, phosphatidylethanolamine, and triglycerides were isolated from minimal deviation hepatoma 7288C cells cultured as monolayers to confluency in roller flasks containing Swims 77...
ㄟ......這個我實在不太會說耶,剛收到HTC 新聞稿,好不容易HTC Sensation在亞洲出現,結果第一個地區是在韓國,由該地電信業者SK TELECOM開賣。也許HTC有他的想法與做法,因此在今天於韓國發表感覺機。當然,我是相信台灣的市場很小啦,不過既然都已經不是首次發表會了,讓台灣發表會盡早一點有這麼困難嗎? 至於新聞稿中提到HTC與韓國合作多密切這種事,我就懶得貼了。
Vodafone has announced that the HTC One M9 is now available to pre-order on their network in the UK and prices start at £19 up front on their £43.50 per month Vodafone Red 4G Price Plan.
TY - JOUR. T1 - Mutation of regulatory serines of rat tyrosine hydroxylase to glutamate. T2 - Effects on enzyme stability and activity. AU - Royo, Montserrat. AU - Fitzpatrick, Paul F.. AU - Daubner, S. Colette. PY - 2005/2/15. Y1 - 2005/2/15. N2 - Tyrosine hydroxylase is phosphorylated at four serine residues in its amino-terminus by multiple kinases. Phosphorylation of serine 40 by cAMP-dependent protein kinase results in alleviation of dopamine inhibition [J. Biol. Chem. 267 (1992) 12639]. The other serines are at positions 8, 19, and 31. The effect of phosphorylation at these serines has been investigated using mutated forms of tyrosine hydroxylase containing glutamates at the positions of the serines. The S8E, S19E, and S31E tyrosine hydroxylase variants have similar steady-state kinetic parameters and similar binding affinity for catecholamines to wild-type enzyme. The S8E, S19E, S31E, and S40E variants differ in stability at elevated temperatures. The S40E variant is the least stable, ...
Cloning and characterization of highly polymorphic porcine microsatellites. The extension coat color locus and the loci for blood group O and tyrosine aminotransferase are on pig chromosome 6
Searcy, G.K.; Senter, S.D.; Wilson, R.L., 1995: Glutamic-Oxaloacetic Transaminase Activity: A Potential End-Point-Temperature Indicator for Imported Cooked Beef †
CP000386.PE405 Location/Qualifiers FT CDS complement(443797..445194) FT /codon_start=1 FT /transl_table=11 FT /locus_tag=Rxyl_0412 FT /product=aminotransferase FT /EC_number=2.6.1.- FT /note=TIGRFAM: 2,4-diaminobutyrate 4-transaminase; PFAM: FT aminotransferase class-III; KEGG: ava:Ava_2839 FT diaminobutyrate--2-oxoglutarate aminotransferase FT /db_xref=EnsemblGenomes-Gn:Rxyl_0412 FT /db_xref=EnsemblGenomes-Tr:ABG03386 FT /db_xref=GOA:Q1AYZ2 FT /db_xref=InterPro:IPR004637 FT /db_xref=InterPro:IPR005814 FT /db_xref=InterPro:IPR015421 FT /db_xref=InterPro:IPR015422 FT /db_xref=InterPro:IPR015424 FT /db_xref=UniProtKB/TrEMBL:Q1AYZ2 FT /protein_id=ABG03386.1 FT /translation=MREGENTLRAESTAAFRARKGLSEGLLERQAARESNARTYPRSIP FT IAVSRARGPYVWDADGRRYLDCLSGAGTLALGHNHPVVVEAIREVLDRGGPLHTLDLAT FT PVKDRFVEELFGSLPRRFAERARIHFCGPAGADAVEAAVKLAKTATGRETVLSFSGGYH FT GMTHGALSLTGKLAPKEPLAGLMPGVHFLPYPYGYRCPFGVGGEDGWRVGARYVERLLD FT DPESGVKRPAAMVLEVVQGEGGSIPAPDGWVREMRRITRERGIPLIVDEIQTGLGRTGT FT ...
Rabbit anti Rat tyrosine hydroxylase (pSer31) antibody recognizes tyrosine hydroxylase (TH), also known as tyrosine 3-monooxygenase, when
Reuber, M, Morphologic and biologic correlation of hyperplastic and neoplastic hepatic lesions occurring spontaneously in c3h x y hybrid mice. (1971). Subject Strain Bibliography 1971. 1817 ...
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Аланинаминотрансфераза (АлАТ, АЛТ, GPT) - внутриклеточный фермент из группы аминотрансфераз, катализирующих взаимопревращения аминокислот и кетокислот путем переноса аминогруппы.. Наиболее высокая активность аланинаминотрансферазы выявляется в печени и почках, меньшая - в сердце, скелетных мышцах, поджелудочной железе, селезенке, легких, эритроцитах. Активность фермента в сыворотке крови у мужчин несколько выше, чем у женщин. Содержание АлАТ в сыворотке крови здоровых людей невелико. Но при разрушении или повреждении клеток, богатых АлАТ ...
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Tryptophan oxygenase (tryptophan 2,3-dioxygenase) activity increases immediately before the initiation of actinomycin D production by Streptomyces parvullus. We have attempted to discern whether this increase is due to a release from catabolite repression or to the synthesis of an inducer substance. The standard culture medium (glutamic acid-histidine-fructose medium) used in antibiotic production studies with S. parvullus contains l-glutamate as a major constituent. l-Glutamate is almost totally consumed before the onset of actinomycin D synthesis. The addition of 10 mM l-glutamate at this stage completely abolished actinomycin D production as well as tryptophan oxygenase synthesis. Fourteen amino acids were tested for a similar effect. Of these, l-glutamate and l-aspartate had the most dramatic effect on tryptophan oxygenase and beta-galactosidase (beta-d-galactosidase), another inducible enzyme. Standard glutamic acid-histidine-fructose medium, preincubated for 23 h to remove l-glutamate, allowed the
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tr:F2QGR3_STROU] alaT; aminotransferase AlaT, aminotransferase, class I; K14260 alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] ...
Earlier in the week the HTC Desire 310 was made official for China, and now HTC have announced the handset for Taiwan. The HTC Desire 310 is equipped with
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Hi, I use HTML component (HTC) to create my own dropdown list and i use an input type text in my .htc to represent my dropdown field. The problem I hav
Google and HTC reached an agreement for $1.1 billion in which HTC will transfer over certain employees and provide access to HTCs intellectually property.
HTC will be announcing its latest One M9 flagship in Barcelona next Sunday and theres a possibility that more than one device will be announced. HTC USA has tweeted a couple of teasers indicating something huge is coming very soon. We dont expect anything huge from its One M9 as…
The retail box of the HTC Desire HD has pretty standard contents: a USB charger, standard microUSB data cable and the usual paperwork. Theres a...
First of all, the present invention provides (a) a polynucleotide comprising a polynucleotide of the nucleotide sequence represented by SEQ ID NO:l or SEQ ID NO:3; and (b) a polynucleotide comprising a polynucleotide coding for a protein of the amino acid sequence represented by SEQ ID NO:2 or SEQ ID NO:4. The polynucleotide can be DNA or RNA. The target polynucleotide of the present invention is not limited to the polynucleotide coding for a branched-chain amino acid aminotransferase gene from beer yeast and may include other polynucleotide coding for proteins having equivalent functions to said protein. Proteins with equivalent functions include, for example, (c) a protein of an amino acid sequence represented by SEQ ID NO:2 or SEQ ID NO:4 with one or more amino acids thereof being deleted, substituted, inserted and/or added and having a branched-chain amino acid aminotransferase activity. Such proteins include a protein consisting of an amino acid sequence represented by SEQ ID NO:2 or SEQ ID ...
We have recently found that ketoconazole inhibits adrenal steroidogenesis; in this paper we investigated whether imidazole antimycotic drugs additionally interact with glucocorticoid receptor sites in target tissues. Our approach was to assess the ability of three drugs: ketoconazole, clotrimazole, and RS 49910, to inhibit [3H]dexamethasone binding to hepatoma tissue culture (HTC) cell cytosol. The results indicated dose-dependent, competitive displacement of [3H]dexamethasone binding that was in the potency sequence: clotrimazole greater than ketoconazole greater than RS 49910. We then examined the functional response of this binding by measuring tyrosine aminotransferase (TAT) activity in HTC cells. The antimycotics did not exhibit TAT agonist activity and inhibition of basal enzyme levels was not detected. However, the drugs were potent antagonists of dexamethasone-induced TAT activity and the effect was temporally reversible. This antagonist activity was in the same sequence and closely ...
Accepted name: cysteine transaminase. Reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate. For diagram click here (mechanism).. Other name(s): cysteine aminotransferase; L-cysteine aminotransferase; CGT. Systematic name: L-cysteine:2-oxoglutarate aminotransferase. Comments: A pyridoxal-phosphate protein.. Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9030-32-4. References: 1. Chatagner, F. and Sauret-Ignazi, G. Role des transamination et du phosphate de pyridoxal dans la formation enzymatique de H2S a partir de la cystéine par le foie du rat en anaérobiose. Bull. Soc. Chim. Biol. 38 (1956) 415-428.. ...
Aminotransferase (AST) is an enzyme thats present in various parts of your body. Your doctor can order an AST test to check the level of aspartate aminotransferase in your blood. Abnormal results may be a sign of liver damage or disease. Learn more about this test.
Sigma-Aldrich offers abstracts and full-text articles by [Carlos Spichiger, Claudia Torres-Farfan, Hugo A Galdames, Natalia Mendez, Pamela Alonso-Vazquez, Hans G Richter].
Aspartate Aminotransferase (AST/GOT) Activity Assay Kit(谷草转氨酶活性测定试剂盒)(ab105135)比色法;敏感度大于10 mU.检测各种样本中谷草转氨酶的活性。
Biosystems Aspartate Aminotransferase (AST-GOT) stabil olmak kaydıyla, yaygın kullanım alanına sahip Biosystems reaktif Ve Cihazlarının
A study of the colorimetric dinitrophenyl-hydrazine method for the determination of serum glutamic oxalacetic transaminase activity.:
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cop:Cp31_1915 K14260 alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] , (GenBank) aspC; Aspartate aminotransferase (A) MSKKDTAPESALLGSAGNPLRRKRRTFDQSDKLKNVLYEIRGPVTALAEKMELDGNTILK LNTGNPAIFGFEAPDVIMRDMIAALSTSQGYSTSKGIIPARRAIVTRYEVIPGFPAFDVD DVYLGNGVSELIMMTMQALLDNGDEVLIPMPDYPLWTAATSLSGGTPVHYLCDEDDDWNP SIEDIRSKVTEKTKAIVVINPNNPTGAVYSPEVLRDIVQVAREHDLLILVDEIYDRILYD GAVHTSIATLAPDLLCITYNGLSKAYRVAGYRAGWMVITGPKHYAHGFIEGIDLLSGTRL CSNVPAQHAIQVALGGRQSIYDLTSEGGRLLEQRNVAWEKLNQIPGVSCVKPMGALYAFP KIDLDYYDIHDDAQLMLDLLRAEKILMVQGTGFNWPQPDHFRVVTLPWAADLAVAMDRLG NFLSSYKQ ...
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It was only recently that Nokia won an injunction against HTC products in the UK, although the ban was later relaxed. Nokia had also recently gone...
The HTC Desire 500 comes in a pillbox-shaped retail package, similar to what debuted last year with the One series. Inside, youll find a set of all-white...